K Fink

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. pmc Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices
    K Fink
    Department of Pharmacology and Toxicology, University of Bonn Medical School, Reuterstrasse 2b, 53113 Bonn, Germany
    Br J Pharmacol 130:900-6. 2000
  2. ncbi request reprint Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex
    Klaus Fink
    Department of Pharmacology and Toxicology, University of Bonn Medical School, Reuterstrasse 2b, 53113 Bonn, Germany
    Neuropharmacology 42:229-36. 2002
  3. ncbi request reprint Effects of cytoskeletal modifications on Ca2+ influx after cerebral ischemia
    K B Fink
    Department of Pharmacology, University of Bonn, Bonn, Germany
    Amino Acids 23:325-9. 2002
  4. ncbi request reprint Ca2+ entry via P/Q-type Ca2+ channels and the Na+/Ca2+ exchanger in rat and human neocortical synaptosomes
    Klaus Fink
    Institut fur Pharmakologie und Toxikologie, Universitatsklinikum Bonn, Reuterstrasse 2b, 53113 Bonn, Germany
    Naunyn Schmiedebergs Arch Pharmacol 366:458-63. 2002
  5. ncbi request reprint 5-HT receptor regulation of neurotransmitter release
    Klaus B Fink
    Department of Pharmacology, Bonn University Clinic, Reuterstr 2b, 53113 Bonn, Germany
    Pharmacol Rev 59:360-417. 2007
  6. ncbi request reprint Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation
    Andreas Meisel
    Klinik und Poliklinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Neurochem 98:1019-31. 2006
  7. doi request reprint Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury
    Ferah Yildirim
    Klinik und Poliklinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Exp Neurol 210:531-42. 2008
  8. ncbi request reprint Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow
    Karen Gertz
    Klinik und Poliklinik fur Neurologie, Charite Campus Mitte, Berlin, Germany
    Circ Res 99:1132-40. 2006
  9. ncbi request reprint Echocardiographic assessment of left ventricular mass in neonatal and adult mice: accuracy of different echocardiographic methods
    Alexander Ghanem
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Bonn, Bonn, Germany
    Echocardiography 23:900-7. 2006
  10. ncbi request reprint Increasing myocardial contraction and blood pressure in C57BL/6 mice during early postnatal development
    Klaus Tiemann
    Department of Pharmacology, Universitätsklinik Bonn, Germany
    Am J Physiol Heart Circ Physiol 284:H464-74. 2003

Collaborators

  • Manfred Gothert
  • Hans Clusmann
  • M Endres
  • D J Dooley
  • Ulrich Laufs
  • Ulrich Dirnagl
  • Christoph Harms
  • Ferah Yildirim
  • Golo Kronenberg
  • Karen Gertz
  • Andreas Meisel
  • Julian Bösel
  • Alexander Ghanem
  • Klaus Tiemann
  • Ulrike Harms
  • Thorsten Lewalter
  • P Chryso Djoufack
  • Benjamin Winter
  • Oliver Dewald
  • Josef Priller
  • Shengbo Ji
  • Jan Schrickel
  • Willi Röll
  • Milan Milosevic
  • Michael Bohm
  • Helmut Schröck
  • Toktam Hashemi
  • Berndt Luderitz
  • Pierre Chryso Djoufack
  • Dirk Megow
  • Florin Gandor
  • Heide Hörtnagl
  • Michael Synowitz
  • Dirk Weyer
  • Christian Grohe
  • Rainer Meyer
  • Ulrike Dreiner

Detail Information

Publications11

  1. pmc Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices
    K Fink
    Department of Pharmacology and Toxicology, University of Bonn Medical School, Reuterstrasse 2b, 53113 Bonn, Germany
    Br J Pharmacol 130:900-6. 2000
    ..The latter effect leads to a reduced activation of AMPA receptors which contribute to K(+)-evoked noradrenaline release from noradrenergic varicosities, resulting in an indirect inhibition of noradrenaline release...
  2. ncbi request reprint Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex
    Klaus Fink
    Department of Pharmacology and Toxicology, University of Bonn Medical School, Reuterstrasse 2b, 53113 Bonn, Germany
    Neuropharmacology 42:229-36. 2002
    ....
  3. ncbi request reprint Effects of cytoskeletal modifications on Ca2+ influx after cerebral ischemia
    K B Fink
    Department of Pharmacology, University of Bonn, Bonn, Germany
    Amino Acids 23:325-9. 2002
    ..Hence, presynaptic Ca(2+) influx and subsequently neuronal vulnerability are attenuated by increased and are aggravated by decreased F-actin depolymerization...
  4. ncbi request reprint Ca2+ entry via P/Q-type Ca2+ channels and the Na+/Ca2+ exchanger in rat and human neocortical synaptosomes
    Klaus Fink
    Institut fur Pharmakologie und Toxikologie, Universitatsklinikum Bonn, Reuterstrasse 2b, 53113 Bonn, Germany
    Naunyn Schmiedebergs Arch Pharmacol 366:458-63. 2002
    ..In addition to the ability of mibefradil to block all voltage-operated Ca(2+) channels, this drug is a low potency inhibitor of the Na(+)/Ca(2+) exchanger...
  5. ncbi request reprint 5-HT receptor regulation of neurotransmitter release
    Klaus B Fink
    Department of Pharmacology, Bonn University Clinic, Reuterstr 2b, 53113 Bonn, Germany
    Pharmacol Rev 59:360-417. 2007
    ....
  6. ncbi request reprint Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation
    Andreas Meisel
    Klinik und Poliklinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Neurochem 98:1019-31. 2006
    ..In conclusion, we demonstrate that the enhancement of gelsolin gene expression correlates with neuroprotection induced by the inhibition of histone deacetylation...
  7. doi request reprint Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury
    Ferah Yildirim
    Klinik und Poliklinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Exp Neurol 210:531-42. 2008
    ..Our results suggest that HDAC inhibitors such as TSA are a promising therapeutic strategy for reducing brain injury following cerebral ischemia...
  8. ncbi request reprint Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow
    Karen Gertz
    Klinik und Poliklinik fur Neurologie, Charite Campus Mitte, Berlin, Germany
    Circ Res 99:1132-40. 2006
    ..Voluntary physical activity improves long-term stroke outcome by eNOS-dependent mechanisms related to improved angiogenesis and cerebral blood flow...
  9. ncbi request reprint Echocardiographic assessment of left ventricular mass in neonatal and adult mice: accuracy of different echocardiographic methods
    Alexander Ghanem
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Bonn, Bonn, Germany
    Echocardiography 23:900-7. 2006
    ..Echocardiographic assessment of LVM is feasible in hearts weighting less than 50 mg and can be estimated best in systole. Hearts weighting more than 50 mg are estimated most accurately by means of LVM-AL at diastole...
  10. ncbi request reprint Increasing myocardial contraction and blood pressure in C57BL/6 mice during early postnatal development
    Klaus Tiemann
    Department of Pharmacology, Universitätsklinik Bonn, Germany
    Am J Physiol Heart Circ Physiol 284:H464-74. 2003
    ..P21 myocytes developed positive staircases at 8 and 10 Hz, and adult myocytes also developed them at 6 Hz. Blood pressure increase during maturation until P50 may originate from increasing single cardiomyocyte contractility...
  11. ncbi request reprint Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones
    Julian Bösel
    Klinik und Poliklinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Neurochem 92:1386-98. 2005
    ..Taken together, atorvastatin exerts specific anti-excitotoxic effects independent of 3-hydroxy-3-methylglutaryl-CoA reductase inhibition, which has potential therapeutic implications...