Fabienne C Fiesel

Summary

Affiliation: University Eye Hospital
Country: Germany

Publications

  1. doi TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration
    Fabienne C Fiesel
    Department of Neurodegeneration, Faculty of Medicine, University of Tuebingen, Tuebingen, Germany
    FEBS J 278:3550-68. 2011
  2. pmc UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination
    Friederike Hans
    From the Graduate School of Cellular and Molecular Neuroscience, University of Tubingen, Tubingen 72076, Germany, Laboratory of Functional Neurogenetics, Department of Neurodegeneration, German Center for Neurodegenerative Diseases DZNE, Tubingen 72076, Germany, Laboratory of Functional Neurogenetics, Department of Neurodegeneration and
    J Biol Chem 289:19164-79. 2014
  3. pmc TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
    Fabienne C Fiesel
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University of Tubingen, 72076 Tubingen, Germany
    Nucleic Acids Res 40:2668-82. 2012
  4. pmc TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6
    Fabienne C Fiesel
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, Otfried Mueller Str, 27, Tuebingen, 72076, Germany
    Mol Neurodegener 6:64. 2011
  5. doi Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans
    Elena M Cornejo Castro
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, German Center for Neurodegenerative Diseases, University of Tubingen, Otfried Muller Strasse 27, 72076 Tubingen, Germany
    J Neural Transm 117:599-604. 2010

Collaborators

  • Philipp J Kahle
  • Jorg B Schulz
  • Friederike Hans
  • Wolfdieter Springer
  • Elena M Cornejo Castro
  • Jennifer C Strong
  • Tobias M Rasse
  • Sandra Jäckel
  • Sven Geisler
  • Aaron Voigt
  • Ingo B Autenrieth
  • Jens Waak
  • Monika Schütz
  • Stephanie S Weber
  • Philipp Oberhettinger

Detail Information

Publications5

  1. doi TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration
    Fabienne C Fiesel
    Department of Neurodegeneration, Faculty of Medicine, University of Tuebingen, Tuebingen, Germany
    FEBS J 278:3550-68. 2011
    ..In this minireview the specific functions of TDP-43 and FUS are described and discussed in the context of how TDP-43 and FUS may contribute to the pathogenesis of frontotemporal lobar degeneration and amyotrophic lateral sclerosis...
  2. pmc UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination
    Friederike Hans
    From the Graduate School of Cellular and Molecular Neuroscience, University of Tubingen, Tubingen 72076, Germany, Laboratory of Functional Neurogenetics, Department of Neurodegeneration, German Center for Neurodegenerative Diseases DZNE, Tubingen 72076, Germany, Laboratory of Functional Neurogenetics, Department of Neurodegeneration and
    J Biol Chem 289:19164-79. 2014
    ..Thus, UBE2E3 and UBPY participate in the regulation of TDP-43 ubiquitination, solubility, and neurodegeneration. ..
  3. pmc TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
    Fabienne C Fiesel
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University of Tubingen, 72076 Tubingen, Germany
    Nucleic Acids Res 40:2668-82. 2012
    ..This indicates a novel mechanism of deregulated translational control upon TDP-43 deficiency, which might contribute to pathogenesis of the protein aggregation diseases frontotemporal dementia and amyotrophic lateral sclerosis...
  4. pmc TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6
    Fabienne C Fiesel
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, Otfried Mueller Str, 27, Tuebingen, 72076, Germany
    Mol Neurodegener 6:64. 2011
    ..abstract:..
  5. doi Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans
    Elena M Cornejo Castro
    Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, German Center for Neurodegenerative Diseases, University of Tubingen, Otfried Muller Strasse 27, 72076 Tubingen, Germany
    J Neural Transm 117:599-604. 2010
    ..Thus, PD-associated DJ-1 contributes to regulation of innate immunity...