Fabian Fehlauer

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint [Treatment results following breast-conserving therapy in primary breast cancer]
    F Fehlauer
    Universitatsklinikum Schleswig Holstein, Campus Lubeck, Klinik für Strahlentherapie und Nuklearmedizin
    Zentralbl Gynakol 127:31-6. 2005
  2. ncbi request reprint Late effects and cosmetic results of conventional versus hypofractionated irradiation in breast-conserving therapy
    Fabian Fehlauer
    Department of Radiation Oncology, University Medical Clinic Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Strahlenther Onkol 181:625-31. 2005
  3. ncbi request reprint Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue
    Fabian Fehlauer
    Department of Radiation Oncology, University of Luebeck, Germany
    Oncol Rep 15:97-105. 2006
  4. ncbi request reprint Effects of irradiation and cisplatin on human glioma spheroids: inhibition of cell proliferation and cell migration
    Fabian Fehlauer
    Department of Radiation Oncology, Universitätsklinikum Eppendorf, University of Hamburg, Martinistr 52, 20254, Hamburg, Germany
    J Cancer Res Clin Oncol 131:723-32. 2005
  5. ncbi request reprint Effect of single dose irradiation on human glioblastoma spheroids in vitro
    Fabian Fehlauer
    Department of Radiation Oncology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Oncol Rep 11:477-85. 2004
  6. ncbi request reprint Health-related quality of life in long term breast cancer survivors treated with breast conserving therapy: impact of age at therapy
    Fabian Fehlauer
    Department of Radiation Oncology, University Clinic Hamburg Eppendorf, Germany
    Breast Cancer Res Treat 92:217-22. 2005
  7. ncbi request reprint Long-term radiation sequelae after breast-conserving therapy in women with early-stage breast cancer: an observational study using the LENT-SOMA scoring system
    Fabian Fehlauer
    Department of Radiation Oncology, University Hospital of Hamburg, Hamburg, Germany
    Int J Radiat Oncol Biol Phys 55:651-8. 2003
  8. ncbi request reprint The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation
    Fabian Fehlauer
    Department of Radiation Oncology, University Clinic Hamburg Eppendorf, UKE, University of Hamburg, D 20246 Hamburg, Germany
    Oncol Rep 17:941-5. 2007
  9. ncbi request reprint Functional outcome and survival after radiotherapy of metastatic spinal cord compression in patients with cancer of unknown primary
    Dirk Rades
    Department of Radiation Oncology, University Hospital Schleswig Holstein, Luebeck, Germany
    Int J Radiat Oncol Biol Phys 67:532-7. 2007
  10. ncbi request reprint Cosmesis from the patient's and the doctor's view
    Ulrike Hoeller
    Department of Radiotherapy and Radiation Oncology, University Hospital, Hamburg, Germany
    Int J Radiat Oncol Biol Phys 57:345-54. 2003

Collaborators

Detail Information

Publications28

  1. ncbi request reprint [Treatment results following breast-conserving therapy in primary breast cancer]
    F Fehlauer
    Universitatsklinikum Schleswig Holstein, Campus Lubeck, Klinik für Strahlentherapie und Nuklearmedizin
    Zentralbl Gynakol 127:31-6. 2005
    ..To evaluate mono-institutional results concerning tumor free survival, overall survival, local tumor control and rate of distant metastasis following breast-conserving therapy...
  2. ncbi request reprint Late effects and cosmetic results of conventional versus hypofractionated irradiation in breast-conserving therapy
    Fabian Fehlauer
    Department of Radiation Oncology, University Medical Clinic Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Strahlenther Onkol 181:625-31. 2005
    ..As the prognosis is general good following BCT, late morbidity and cosmesis are important. The present study compares two different radiation schedules with respect to these two endpoints...
  3. ncbi request reprint Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue
    Fabian Fehlauer
    Department of Radiation Oncology, University of Luebeck, Germany
    Oncol Rep 15:97-105. 2006
    ..Only minor morphological damage was observed. Confocal laser scanning microscopy identified an increased dead cell core after dFdC + RT (50%). In conclusion, dFdC can lead to an additively radioenhancement in CLS and individual OMS...
  4. ncbi request reprint Effects of irradiation and cisplatin on human glioma spheroids: inhibition of cell proliferation and cell migration
    Fabian Fehlauer
    Department of Radiation Oncology, Universitätsklinikum Eppendorf, University of Hamburg, Martinistr 52, 20254, Hamburg, Germany
    J Cancer Res Clin Oncol 131:723-32. 2005
    ....
  5. ncbi request reprint Effect of single dose irradiation on human glioblastoma spheroids in vitro
    Fabian Fehlauer
    Department of Radiation Oncology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Oncol Rep 11:477-85. 2004
    ..Particularly early changes in proliferation and apoptosis can be observed in spheroids. Individual response differences suggest spheroids of human gliomas to be useful for monitoring radiosurgery effects...
  6. ncbi request reprint Health-related quality of life in long term breast cancer survivors treated with breast conserving therapy: impact of age at therapy
    Fabian Fehlauer
    Department of Radiation Oncology, University Clinic Hamburg Eppendorf, Germany
    Breast Cancer Res Treat 92:217-22. 2005
    ..Aim was to compare the functional status in long-term breast cancer survivors related to age at diagnosis and to asses the effects of adjuvant therapy on health-related quality of life (HRQoL)...
  7. ncbi request reprint Long-term radiation sequelae after breast-conserving therapy in women with early-stage breast cancer: an observational study using the LENT-SOMA scoring system
    Fabian Fehlauer
    Department of Radiation Oncology, University Hospital of Hamburg, Hamburg, Germany
    Int J Radiat Oncol Biol Phys 55:651-8. 2003
    ..To evaluate the long-term toxicity after breast-conserving therapy in women with early-stage breast cancer...
  8. ncbi request reprint The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation
    Fabian Fehlauer
    Department of Radiation Oncology, University Clinic Hamburg Eppendorf, UKE, University of Hamburg, D 20246 Hamburg, Germany
    Oncol Rep 17:941-5. 2007
    ..7/1.8 (0.025 mmol TZM), and 1.5/1.4 (0.05 mmol TZM). In terms of inhibition of proliferation and migration, irradiation can lead to an enhancement of the TZM effect in human glioma spheroids, which is less than additive...
  9. ncbi request reprint Functional outcome and survival after radiotherapy of metastatic spinal cord compression in patients with cancer of unknown primary
    Dirk Rades
    Department of Radiation Oncology, University Hospital Schleswig Holstein, Luebeck, Germany
    Int J Radiat Oncol Biol Phys 67:532-7. 2007
    ..Patients with cancer of unknown primary (CUP) account for about 10% of patients with metastatic spinal cord compression (MSCC). This study aims to define the appropriate radiation regimen for these patients...
  10. ncbi request reprint Cosmesis from the patient's and the doctor's view
    Ulrike Hoeller
    Department of Radiotherapy and Radiation Oncology, University Hospital, Hamburg, Germany
    Int J Radiat Oncol Biol Phys 57:345-54. 2003
    ..Factors that determine judgment of cosmesis are analyzed. Also, a patient questionnaire was designed to screen for normal tissue reactions and is evaluated...
  11. ncbi request reprint Prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Germany
    J Clin Oncol 24:3388-93. 2006
    ..To evaluate potential prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression (MSCC)...
  12. pmc Well-differentiated neurocytoma: what is the best available treatment?
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Neuro Oncol 7:77-83. 2005
    ..A radiation dose of 54 Gy appeared sufficient. Application of postoperative radiotherapy should be decided individually, taking into account the risk of local failure, the need for another craniotomy, and potential radiation toxicity...
  13. ncbi request reprint Dose-effect relationship for radiotherapy after incomplete resection of atypical neurocytomas
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Radiother Oncol 74:67-9. 2005
    ..001) and survival (P=0.02). Doses (EQD2) >54 Gy were associated with better 5-year local control (84% versus 55%, P=0.05) and 5-year-survival (84% versus 65%, P=0.18) than doses < or =54 Gy...
  14. ncbi request reprint Toxicity of two cisplatin-based radiochemotherapy regimens for the treatment of patients with stage III/IV head and neck cancer
    Dirk Rades
    Department of Radiation Oncology, University Hospital Schleswig Holstein, Campus Luebeck, Luebeck, Germany
    Head Neck 30:235-41. 2008
    ..This nonrandomized study compared 2 radiochemotherapy regimens for toxicity in 128 patients with stage III/IV head and neck cancer...
  15. ncbi request reprint Reducing the overall treatment time for radiotherapy of metastatic spinal cord compression (MSCC): 3-year results of a prospective observational multi-center study
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg, Hamburg, Germany
    J Neurooncol 70:77-82. 2004
    ..This prospective multi-center study investigates a reduction of the overall treatment time for radiotherapy of MSCC, which is important for these mostly disabled patients...
  16. ncbi request reprint Prognostic value of the MIB-1 labeling index for central neurocytomas
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Neurology 62:987-9. 2004
    ..The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004)...
  17. ncbi request reprint Is there a life-long risk of brachial plexopathy after radiotherapy of supraclavicular lymph nodes in breast cancer patients?
    Amira Bajrovic
    Department of Radiotherapy and Radiation Oncology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Radiother Oncol 71:297-301. 2004
    ..To contribute to the question whether the risk of radiation-related brachial plexopathy increases, remains constant or decreases with time after treatment...
  18. ncbi request reprint Treatment of atypical neurocytomas
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Cancer 100:814-7. 2004
    ..The objective of this analysis was to define the optimal treatment for patients with these atypical tumors...
  19. ncbi request reprint Prognostic factors in head-and-neck cancer patients treated with surgery followed by intensity-modulated radiotherapy (IMRT), 3D-conformal radiotherapy, or conventional radiotherapy
    Dirk Rades
    Department of Radiation Oncology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Oral Oncol 43:535-43. 2007
    ..The three radiation techniques provided similar disease control. IMRT was effective in significantly reducing xerostomia...
  20. ncbi request reprint Defining the best available treatment for neurocytomas in children
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Cancer 101:2629-32. 2004
    ..Since this entity was introduced in 1982, approximately 60 cases have been reported among patients age </= =18 years of age. The current analysis was performed to define the best available neurocytoma therapy in children...
  21. ncbi request reprint A prospective evaluation of two radiotherapy schedules with 10 versus 20 fractions for the treatment of metastatic spinal cord compression: final results of a multicenter study
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg, Hamburg, Germany
    Cancer 101:2687-92. 2004
    ..The current observational multicenter study, performed prospectively by the authors, evaluated two radiotherapy (RT) schedules and prognostic factors with respect to functional outcome..
  22. ncbi request reprint Increasing the rate of late toxicity by changing the score? A comparison of RTOG/EORTC and LENT/SOMA scores
    Ulrike Hoeller
    Department of Radiation Oncology, University Hospital Eppendorf, Hamburg, Germany
    Int J Radiat Oncol Biol Phys 55:1013-8. 2003
    ..The impact of the classification system on grading late effects was evaluated...
  23. ncbi request reprint Serious adverse effects of amifostine during radiotherapy in head and neck cancer patients
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg D 20246, Germany
    Radiother Oncol 70:261-4. 2004
    ..This is the first report focusing on amifostine related adverse effects leading to discontinuation of amifostine treatment...
  24. ncbi request reprint Defining the optimal dose of radiation after incomplete resection of central neurocytomas
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Germany
    Int J Radiat Oncol Biol Phys 55:373-7. 2003
    ..Central neurocytomas are uncommon benign central nervous system tumors. There is uncertainty regarding the most appropriate radiation dose after incomplete resection. This analysis was performed to determine the optimal dose...
  25. ncbi request reprint Treatment options for central neurocytoma
    Dirk Rades
    Department of Radiation Oncology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Neurology 59:1268-70. 2002
    ..The data suggest that complete resection leads to significantly better local control and survival than incomplete resection. After incomplete resection, patients benefit from postoperative radiotherapy...
  26. ncbi request reprint Randomized phase III trial of postoperative radiochemotherapy +/- amifostine in head and neck cancer. Is there evidence for radioprotection?
    Peter Vacha
    Department of Radiation Oncology and Nuclear Medicine, University of Lubeck, Germany
    Strahlenther Onkol 179:385-9. 2003
    ..We investigated this issue in a randomized trial comparing radiochemotherapy (RT + CT) versus radiochemotherapy plus amifostine (RC + CT + A) in patients with head and neck cancer...
  27. ncbi request reprint [Treatment for central neurocytoma: a meta-analysis based on the data of 358 patients]
    Dirk Rades
    Abteilung für Strahlentherapie und Radioonkologie, Universitatsklinikum Hamburg Eppendorf, Hamburg, Deutschland
    Strahlenther Onkol 179:213-8. 2003
    ....
  28. ncbi request reprint Letter to 'central neurocytoma with craniospinal dissemination' by H. Takao et al
    Dirk Rades
    J Neurooncol 67:127-8; author reply 128. 2004