Stefan A Farkas

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice
    S Farkas
    Department of Surgery, Klinik und Poliklinik für Chirurgie, Klinikum der Universitat Regensburg, Regensburg, Germany
    Clin Exp Immunol 126:250-8. 2001
  2. pmc Short-term treatment with anti-CD44v7 antibody, but not CD44v4, restores the gut mucosa in established chronic dextran sulphate sodium (DSS)-induced colitis in mice
    S Farkas
    Department of Surgery, University of Regensburg, Germany
    Clin Exp Immunol 142:260-7. 2005
  3. ncbi request reprint Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:747-53. 2006
  4. doi request reprint Calcineurin inhibitor minimization protocols in liver transplantation
    Stefan A Farkas
    Department of Surgery, University Hospital Regensburg, Germany
    Transpl Int 22:49-60. 2009
  5. ncbi request reprint Preferential migration of CD62L cells into the appendix in mice with experimental chronic colitis
    S A Farkas
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Eur Surg Res 37:115-22. 2005
  6. ncbi request reprint Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:71-8. 2006
  7. ncbi request reprint Conditioning of liver grafts with prostaglandins improves bile acid transport
    S Farkas
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Transplant Proc 37:435-8. 2005
  8. doi request reprint Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?
    Jens M Werner
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    Transpl Immunol 25:27-33. 2011
  9. ncbi request reprint DX5+ NKT cells induce the death of colitis-associated cells: involvement of programmed death ligand-1
    Matthias Hornung
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Eur J Immunol 36:1210-21. 2006
  10. pmc Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study
    Andreas A Schnitzbauer
    Department of Surgery, Regensburg University Hospital, Regensburg, Germany
    BMC Nephrol 11:24. 2010

Collaborators

Detail Information

Publications21

  1. pmc Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice
    S Farkas
    Department of Surgery, Klinik und Poliklinik für Chirurgie, Klinikum der Universitat Regensburg, Regensburg, Germany
    Clin Exp Immunol 126:250-8. 2001
    ....
  2. pmc Short-term treatment with anti-CD44v7 antibody, but not CD44v4, restores the gut mucosa in established chronic dextran sulphate sodium (DSS)-induced colitis in mice
    S Farkas
    Department of Surgery, University of Regensburg, Germany
    Clin Exp Immunol 142:260-7. 2005
    ..Short-term treatment with anti-CD44v7 antibody blocks T cell extravasation and recruitment to the intestinal mucosa and cures established experimental colitis...
  3. ncbi request reprint Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:747-53. 2006
    ..The aim of the present study was to test the immunosuppressive mammalian target of rapamycin inhibitor rapamycin in an experimental model of chronic colitis and to compare its effectiveness with CsA...
  4. doi request reprint Calcineurin inhibitor minimization protocols in liver transplantation
    Stefan A Farkas
    Department of Surgery, University Hospital Regensburg, Germany
    Transpl Int 22:49-60. 2009
    ..This review gave an overview on CNI minimization protocols in liver transplantation also focusing on recently analyzed studies...
  5. ncbi request reprint Preferential migration of CD62L cells into the appendix in mice with experimental chronic colitis
    S A Farkas
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Eur Surg Res 37:115-22. 2005
    ..Clinical and experimental studies suggest that appendectomy can protect against development of ulcerative colitis and Crohn's disease. However, how T cells in the appendix affect the development of colitis has not been clarified...
  6. ncbi request reprint Blocking MAdCAM-1 in vivo reduces leukocyte extravasation and reverses chronic inflammation in experimental colitis
    Stefan Farkas
    Department of Surgery, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Int J Colorectal Dis 21:71-8. 2006
    ..Here, we investigate the pathophysiologic role of MAdCAM-1 in the intestinal microcirculation in vivo...
  7. ncbi request reprint Conditioning of liver grafts with prostaglandins improves bile acid transport
    S Farkas
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Transplant Proc 37:435-8. 2005
    ....
  8. doi request reprint Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?
    Jens M Werner
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    Transpl Immunol 25:27-33. 2011
    ..Here, we investigated whether the distribution of T, NK and CD3(+)CD56(+)NKT cells is altered in transplanted livers under different circumstances...
  9. ncbi request reprint DX5+ NKT cells induce the death of colitis-associated cells: involvement of programmed death ligand-1
    Matthias Hornung
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Eur J Immunol 36:1210-21. 2006
    ..Therefore, DX5+ NKT cells could be important in the regulation of immune responses associated with chronic colitis...
  10. pmc Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study
    Andreas A Schnitzbauer
    Department of Surgery, Regensburg University Hospital, Regensburg, Germany
    BMC Nephrol 11:24. 2010
    ..This is a single-center study pilot-study (PATRON07) investigating safety and efficacy of CNI-free, "bottom-up" immunosuppressive (IS) strategy in patients undergoing liver transplantation (LT) with renal impairment prior to LT...
  11. doi request reprint Double deficiency for RORγt and T-bet drives Th2-mediated allograft rejection in mice
    Manije Sabet-Baktach
    Department of Surgery, University Hospital Regensburg, University of Regensburg, 93053 Regensburg, Germany
    J Immunol 191:4440-6. 2013
    ..Moreover, Eomes may rescue Th1-mediated allograft rejection in the absence of IL-4, T-bet, and RORγt. ..
  12. doi request reprint Bile duct damage after cold storage of deceased donor livers predicts biliary complications after liver transplantation
    Stefan M Brunner
    Department of Surgery, University Medical Center Regensburg, Regensburg, Germany
    J Hepatol 58:1133-9. 2013
    ..The aim of this study was to examine the development of biliary epithelial damage between organ retrieval and transplantation and its clinical relevance for patients...
  13. pmc DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice
    Jens M Werner
    Department of Surgery, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    BMC Immunol 12:26. 2011
    ..Therefore, we investigated the expression of several T cell and NK cell markers, as well as functional parameters in spleen and liver subsets of DX5+NKT cells in NK1.1- Balb/c mice and compared our findings to NK1.1+ C57Bl/6 mice...
  14. doi request reprint Unconventional RORγt+ T cells drive hepatic ischemia reperfusion injury
    Elke Eggenhofer
    Department of Surgery, University Hospital Regensburg, University of Regensburg, 93053 Regensburg, Germany
    J Immunol 191:480-7. 2013
    ..Therefore, identification of CD27(-)γδTCR(+) and CD4(-)CD8(-) double-negative T cells as the major source of IL-17A via RORγt in hepatic IRI opens new therapeutic options to improve liver transplantation outcomes...
  15. doi request reprint Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings
    Andreas A Schnitzbauer
    Department of Surgery, University Hospital Regensburg, Regensburg, Germany
    Ann Surg 255:405-14. 2012
    ..To evaluate a new 2-step technique for obtaining adequate but short-term parenchymal hypertrophy in oncologic patients requiring extended right hepatic resection with limited functional reserve...
  16. ncbi request reprint Macrophages driven to a novel state of activation have anti-inflammatory properties in mice
    Beate G Brem-Exner
    Department of Surgery, University of Regensburg, Germany
    J Immunol 180:335-49. 2008
    ..We conclude that IFNgamma-MdC represent macrophages in a novel state of activation, possessing multiple T cell-suppressive effects with therapeutic potential for the treatment of autoimmune inflammation...
  17. ncbi request reprint Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
    Markus Guba
    Department of Surgery, University of Regensburg, Regensburg, Germany
    Nat Med 8:128-35. 2002
    ..Thus, the use of RAPA, instead of cyclosporine, may reduce the chance of recurrent or de novo cancer in high-risk transplant patients...
  18. ncbi request reprint rAAV-mediated stable expression of heme oxygenase-1 in stellate cells: a new approach to attenuate liver fibrosis in rats
    Tung Yu Tsui
    Center for the Study of Liver Disease, University of Hong Kong, Pokfulam, Hong Kong, China
    Hepatology 42:335-42. 2005
    ..With this approach, the severity of established micronodular cirrhosis was markedly reduced. In conclusion, these findings suggest a new approach for the treatment of liver fibrosis using adeno-associated virus-mediated gene transfer...
  19. ncbi request reprint RANTES/CCL5 polymorphisms as a risk factor for recurrent acute rejection
    Bernd Krüger
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Regensburg, Germany
    Clin Transplant 21:385-90. 2007
    ..1T/C) are associated with a different expression of this chemokine as well as the occurrence of cardiovascular disease. Therefore, we investigated the impact of these three polymorphisms on the outcome after renal transplantation...
  20. doi request reprint No effect of C-reactive protein (CRP) haplotypes on CRP levels and post-transplant morbidity and mortality in renal transplantation
    Bernd Krüger
    Klinik und Poliklinik fur Innere Medizin II, Universitat Regensburg, Regensburg, Germany
    Transpl Int 21:452-8. 2008
    ....
  21. ncbi request reprint Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils
    Anja A Kuhl
    Medizinische Klinik I, Campus Benjamin Franklin, Charite, Berlin, Germany
    Gastroenterology 133:1882-92. 2007
    ..The objective of this study was to evaluate whether blocking the invasion of neutrophils by anti-L-selectin monoclonal antibodies modulates chemically induced colitis and how this modulation is accomplished...