T C Erren

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint A generalized theory of carcinogenesis due to chronodisruption
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Cologne, Germany
    Neuro Endocrinol Lett 29:815-21. 2008
  2. ncbi request reprint How to have an effective academic sabbatical: recommendations for what to do and what to avoid
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 31:725-7. 2010
  3. ncbi request reprint Shift work and cancer research: a thought experiment into a potential chronobiological fallacy of past and perspectives for future epidemiological studies
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, Environmental Medicine and Prevention Research, Uniklinik Köln, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 34:282-6. 2013
  4. doi request reprint Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine, and Prevention Research, University of Cologne, Lindenthal, Cologne, Germany
    Naturwissenschaften 100:291-8. 2013
  5. doi request reprint What do we know 40 years after nixon declared the 'war on cancer'? On the origin, prevention and treatment of cancer
    Thomas C Erren
    Institute and Policlinic for Occupational, Social and Environmental Medicine and Prevention Research, School of Medicine and Dentistry, University of Cologne, Kerpener Str 62, 50937, Cologne, Germany
    J Cancer Educ 27:597-600. 2012
  6. ncbi request reprint Chronomedicine: an old concept's fledging? A selective literature search
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:357-60. 2012
  7. ncbi request reprint Sleep duration and cancer risk: time to use a "sleep-years" index?
    Thomas C Erren
    Cancer Causes Control 23:1399-403. 2012
  8. ncbi request reprint A perinatal signature of light on chronobiology? If so, numerous questions arise and experimental animal research must provide more information
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:318-20. 2012
  9. ncbi request reprint A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude concepts
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:314-7. 2012
  10. doi request reprint Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Strasse 62, 50937 Cologne, Lindenthal, Germany
    Int Arch Occup Environ Health 82:997-1004. 2009

Detail Information

Publications49

  1. ncbi request reprint A generalized theory of carcinogenesis due to chronodisruption
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Cologne, Germany
    Neuro Endocrinol Lett 29:815-21. 2008
    ....
  2. ncbi request reprint How to have an effective academic sabbatical: recommendations for what to do and what to avoid
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 31:725-7. 2010
    ..Here we provide practical recommendations [1-4: pre-sabbatical; 5-8: intra-sabbatical; 9-10: post-sabbatical] for making your sabbatical a satisfying endeavor...
  3. ncbi request reprint Shift work and cancer research: a thought experiment into a potential chronobiological fallacy of past and perspectives for future epidemiological studies
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, Environmental Medicine and Prevention Research, Uniklinik Köln, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 34:282-6. 2013
    ..In addition, we consider first empirical evidence from recent research which avoided such bias. Methodological perspectives for future chronobiology-driven epidemiological research are outlined. ..
  4. doi request reprint Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine, and Prevention Research, University of Cologne, Lindenthal, Cologne, Germany
    Naturwissenschaften 100:291-8. 2013
    ..In an a priori way, we examine possible outcomes and perspectives for preventive measures following from our rationale and the suggested chronobiology-driven studies and close with overall advances of chronodisruption research...
  5. doi request reprint What do we know 40 years after nixon declared the 'war on cancer'? On the origin, prevention and treatment of cancer
    Thomas C Erren
    Institute and Policlinic for Occupational, Social and Environmental Medicine and Prevention Research, School of Medicine and Dentistry, University of Cologne, Kerpener Str 62, 50937, Cologne, Germany
    J Cancer Educ 27:597-600. 2012
    ....
  6. ncbi request reprint Chronomedicine: an old concept's fledging? A selective literature search
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:357-60. 2012
    ..Overall, due to the "maturing" of chronomedicine as a field, the near future might bring a section dedicated to chronomedicine in existing journals, or even a "Journal of Chronomedicine" as vectors of ideas and research...
  7. ncbi request reprint Sleep duration and cancer risk: time to use a "sleep-years" index?
    Thomas C Erren
    Cancer Causes Control 23:1399-403. 2012
    ....
  8. ncbi request reprint A perinatal signature of light on chronobiology? If so, numerous questions arise and experimental animal research must provide more information
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:318-20. 2012
    ....
  9. ncbi request reprint A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude concepts
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 33:314-7. 2012
    ....
  10. doi request reprint Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Strasse 62, 50937 Cologne, Lindenthal, Germany
    Int Arch Occup Environ Health 82:997-1004. 2009
    ..This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis...
  11. pmc Attributing the burden of cancer at work: three areas of concern when examining the example of shift-work
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Germany
    Epidemiol Perspect Innov 8:4. 2011
    ..Overall, causal, practical and methodological areas of concern should be diligently considered when performing and interpreting AF or BOD computations which - at least at the present time - may not be defensible...
  12. doi request reprint Light Hygiene: Time to make preventive use of insights--old and new--into the nexus of the drug light, melatonin, clocks, chronodisruption and public health
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Kerpener Strasse 62, 50937 Koln, Lindenthal, Germany
    Med Hypotheses 73:537-41. 2009
    ..And yet, since light possesses a rather unique and exclusive Zeitgeber role and in view of its ubiquitous nature, a specific, preventative focus on "light hygiene", as a contribution to a general "Zeitgeber hygiene", is warranted...
  13. ncbi request reprint Shift work, chronodisruption and cancer?--The IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Str 62, 50937 Koln, Germany
    Scand J Work Environ Health 35:74-9. 2009
    ..This overview summarizes the key ideas presented at the Cologne Colloquium and offers 10 theses concerning the need for targeted studies and the necessity to develop possible means of prevention...
  14. ncbi request reprint Clockwork blue: on the evolution of non-image-forming retinal photoreceptors in marine and terrestrial vertebrates
    T C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Strasse 62, Koln, Lindenthal, Germany
    Naturwissenschaften 95:273-9. 2008
    ....
  15. doi request reprint Defining chronodisruption
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Koln, Lindenthal, Germany
    J Pineal Res 46:245-7. 2009
    ..We hope that defining CD can contribute to studies which may help to find clues to a background incidence of epidemic internal cancers for which--so far in many cases--we lack causal explanations...
  16. ncbi request reprint Meta-analyses of published epidemiological studies, 1979-2006, point to open causal questions in silica-silicosis-lung cancer research
    T C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Germany
    Med Lav 102:321-35. 2011
    ..The objective was to examine in depth whether current data allows to answer the pressing question "does silica cause lung cancer in the absence of silicosis"?..
  17. ncbi request reprint Axelrod, the pineal and the melatonin hypothesis: lessons of 50 years to shape chronodisruption research
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
    Neuro Endocrinol Lett 31:585-7. 2010
    ....
  18. ncbi request reprint Research into the chronodisruption-cancer theory: the imperative for causal clarification and the danger of causal reductionism
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Kerpener Strasse 62, 50937 Koln, Lindenthal, Germany
    Neuro Endocrinol Lett 31:1-3. 2010
    ..Second, we emphasize the importance of considering the Zeitgeber multiplicity to avoid causal reductionism in epidemiologic - but also other - chronodisruption research...
  19. pmc Shift work, cancer and "white-box" epidemiology: Association and causation
    Thomas C Erren
    Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research University of Cologne, Kerpener Straße 62, Haus 11 B, 50937 Koln, Germany
    Epidemiol Perspect Innov 7:11. 2010
    ..Sir Richard Doll 1...
  20. doi request reprint Chronodisruption and cancer
    Thomas C Erren
    School of Medicine and Dentistry, University of Cologne, Cologne, Germany
    Naturwissenschaften 95:367-82. 2008
    ....
  21. ncbi request reprint A meta-analysis of epidemiologic studies of electric and magnetic fields and breast cancer in women and men
    T C Erren
    Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Germany
    Bioelectromagnetics . 2001
    ..The paramount methodological problem inhibiting valid conclusions about an association between EMF and breast cancer is the probable misclassification of exposure and the possible misclassification of the disease itself...
  22. ncbi request reprint [Light, melatonin and internal cancers - recent facts and research perspectives]
    T C Erren
    Institut und Poliklinik für Arbeits und Sozialmedizin, Klinikum der Universität zu Köln, Germany
    Gesundheitswesen 64:278-83. 2002
    ..Further epidemiological investigations can contribute to the understanding of the patho-physiological relationships between light, melatonin and human biology...
  23. ncbi request reprint Does light cause internal cancers? The problem and challenge of an ubiquitous exposure
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Köln Lindenthal, Germany
    Neuro Endocrinol Lett 23:61-70. 2002
    ....
  24. ncbi request reprint ELF-EMF, endocrine disruptors, light: what if we apply triage to research?
    T C Erren
    Institut und Poliklinik für Arbeitsmedizin, Sozialmedizin und Sozialhygiene, Klinikum der Universität zu Köln, Joseph Stelzmann Strasse 9, 50924 Cologne Lindenthal, Germany
    Med Hypotheses 59:212-4. 2002
    ....
  25. ncbi request reprint Preventive research and interventive research: in favour of to act rather than to react
    T C Erren
    Institut und Poliklinik für Arbeitsmedizin, Sozialmedizin und Sozialhygiene, Klinikum der Universität zu Köln, Joseph Stelzmann Strasse 9, 50924 Cologne Lindenthal, Germany
    Med Hypotheses 59:215-22. 2002
    ..Based also on conceptual considerations it is concluded that, while both research approaches are needed, a strategy with more emphasis on preventive research and taking action at an earlier stage may lead to more community success...
  26. ncbi request reprint Light, timing of biological rhythms, and chronodisruption in man
    Thomas C Erren
    Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924, Cologne, Germany
    Naturwissenschaften 90:485-94. 2003
    ..We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention...
  27. ncbi request reprint Can fat explain the human brain's big bang evolution?-Horrobin's leads for comparative and functional genomics
    T C Erren
    Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln Lindenthal, Germany
    Prostaglandins Leukot Essent Fatty Acids 70:345-7. 2004
    ....
  28. ncbi request reprint The quest for questions -- on the logical force of science
    Thomas C Erren
    Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry University of Cologne, Germany
    Med Hypotheses 62:635-40. 2004
    ..It is concluded that questions and hypotheses as their formal expression must be strongly encouraged: appropriate answers and crucial tests will ultimately follow...
  29. ncbi request reprint The chronosense -- what light tells man about biological time
    Thomas C Erren
    Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln, Lindenthal, Germany
    Med Hypotheses 63:1074-80. 2004
    ..We conclude that syndisciplinary research into the physiology and pathophysiological implications of the chronosense is warranted and summarize a series of research questions...
  30. ncbi request reprint Could visible light contribute to the development of leukaemia and other cancers in children?
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln, Lindenthal, Germany
    Med Hypotheses 64:864-71. 2005
    ..In fact, it could be much easier -- and much more effective -- to reevaluate and modify lighting systems than to manipulate other possible determinants of the chronic processes of cancer such as genetic, nutritional or lifestyle factors...
  31. pmc Shift work and cancer: the evidence and the challenge
    Thomas C Erren
    Institut und Poliklinik für Arbeitsmedizin, Umweltmedizin und Präventionsforschung, Universitat zu Koln, Koln, Germany
    Dtsch Arztebl Int 107:657-62. 2010
    ..This review provides background and practical information with regard to the open question "does shift-work cause cancer?"..
  32. ncbi request reprint The case for a posteriori hypotheses to fuel scientific progress
    Thomas C Erren
    Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Köln, Lindenthal, Germany
    Med Hypotheses 69:448-53. 2007
    ..In this vein, a posteriori hypotheses should be encouraged as a thinker's prime tool rather than be discouraged. Indeed, it is suggested, that information on a posteriori hypotheses should be formally required when research is published...
  33. ncbi request reprint Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisited
    T C Erren
    Institut und Poliklinik für Arbeits und Sozialmedizin der Universität zu Köln, Cologne Lindenthal, Germany
    Med Hypotheses 53:1-5. 1999
    ..Since these observations are consistent with our corollary and the associated prediction, we suggest that research on a melatonin-inhibited carcinogenesis in the low-risk populations of the Arctic should be pursued...
  34. doi request reprint Epigenetics: origins and implications for cancer epidemiology
    Melissa S Nise
    Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Cologne Lindenthal, Germany
    Med Hypotheses 74:377-82. 2010
    ....
  35. ncbi request reprint Urinary 6-sulfatoxymelatonin excretion in humans during domestic exposure to 50 hertz electromagnetic fields
    Pierluigi Cocco
    Department of Public Health, Occupational Health Section, University of Cagliari, Italy
    Neuro Endocrinol Lett 26:136-42. 2005
    ..We investigated the effects of residential exposure to ELF-EMF on the excretion of urinary 6-sulfatoxymelatonin (6-OHMS), the major melatonin metabolite, as an indicator of nocturnal melatonin secretion...
  36. pmc The long and thorny road to publication in quality journals
    Thomas C Erren
    PLoS Comput Biol 3:e251. 2007
  37. pmc Ten simple rules for a good poster presentation
    Thomas C Erren
    PLoS Comput Biol 3:e102. 2007
  38. ncbi request reprint Prizes to solve problems in and beyond medicine, big and small: it can work
    Thomas C Erren
    Med Hypotheses 68:732-4. 2007
    ..Provided that glittering prizes are offered and awarded with care, they can lead to effective problem-solving in medicine and related biomedical sciences as well...
  39. ncbi request reprint Comparing Neanderthal and human genomes
    Thomas C Erren
    Science 315:1664; author reply 1664. 2007
  40. ncbi request reprint Health clues from polar regions
    Thomas C Erren
    Science 316:540. 2007
  41. pmc "Simple rules for editors"? Here is one rule to tackle neglected problems of publishing
    Thomas C Erren
    PLoS Comput Biol 3:e88; discussion e89. 2007
  42. ncbi request reprint Silica and lung cancer
    Thomas C Erren
    Epidemiology 18:521; author reply 521-2. 2007
  43. ncbi request reprint Neanderthal, chimp and human genomes: hypotheses wanted for research into brain evolution
    Thomas C Erren
    Med Hypotheses 70:4-7. 2008
    ..Rather than pursuing black box genomics, we suggest that genetic analyses should be guided by hypotheses. One plausible candidate in this regard is the"fat-utilization" hypothesis proposed by the late David Horrobin...
  44. ncbi request reprint Hamming's "open doors" and group creativity as keys to scientific excellence: the example of Cambridge
    Thomas C Erren
    Med Hypotheses 70:473-7. 2008
    ....
  45. pmc Ten simple rules for doing your best research, according to Hamming
    Thomas C Erren
    PLoS Comput Biol 3:1839-40. 2007
  46. doi request reprint Frog transparency led to discovery of melatonin
    Thomas C Erren
    Nature 451:127. 2008
  47. doi request reprint Results of rush to sequence genomes may be nonsense
    Thomas C Erren
    Nature 452:151. 2008
  48. doi request reprint Not all shifts are equal: it's time for comprehensive exposure metrics in chronodisruption research
    Thomas C Erren
    Cancer Res 68:4011. 2008
  49. ncbi request reprint Biologically based study of magnetic field exposure and female breast cancer--will there be a sensible interpretation without information on a likely culprit?
    Thomas C Erren
    Epidemiology 14:129-30. 2003