Research Topics
| T C ErrenSummaryAffiliation: University of Cologne Country: Germany Publications
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Detail Information
Publications
How to have an effective academic sabbatical: recommendations for what to do and what to avoidThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Lindenthal, Germany
Neuro Endocrinol Lett 31:725-7. 2010..Here we provide practical recommendations [1-4: pre-sabbatical; 5-8: intra-sabbatical; 9-10: post-sabbatical] for making your sabbatical a satisfying endeavor...
What do we know 40 years after nixon declared the 'war on cancer'? On the origin, prevention and treatment of cancerThomas C Erren
Institute and Policlinic for Occupational, Social and Environmental Medicine and Prevention Research, School of Medicine and Dentistry, University of Cologne, Kerpener Str 62, 50937, Cologne, Germany
J Cancer Educ 27:597-600. 2012....
Chronomedicine: an old concept's fledging? A selective literature searchThomas C Erren
Institute and Policlinic for Occupational Medicine, University of Cologne, Lindenthal, Germany
Neuro Endocrinol Lett 33:357-60. 2012..Overall, due to the "maturing" of chronomedicine as a field, the near future might bring a section dedicated to chronomedicine in existing journals, or even a "Journal of Chronomedicine" as vectors of ideas and research...
Sleep duration and cancer risk: time to use a "sleep-years" index?Thomas C Erren
Cancer Causes Control 23:1399-403. 2012....
A perinatal signature of light on chronobiology? If so, numerous questions arise and experimental animal research must provide more informationThomas C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
Neuro Endocrinol Lett 33:318-20. 2012....
A possible role of perinatal light in mood disorders and internal cancers: reconciliation of instability and latitude conceptsThomas C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
Neuro Endocrinol Lett 33:314-7. 2012....
Defining chronodisruptionThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Koln, Lindenthal, Germany
J Pineal Res 46:245-7. 2009..We hope that defining CD can contribute to studies which may help to find clues to a background incidence of epidemic internal cancers for which--so far in many cases--we lack causal explanations...
A generalized theory of carcinogenesis due to chronodisruptionThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Cologne, Germany
Neuro Endocrinol Lett 29:815-21. 2008....
Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health questionThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Strasse 62, 50937 Cologne, Lindenthal, Germany
Int Arch Occup Environ Health 82:997-1004. 2009..This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis...
Chronodisruption and cancerThomas C Erren
School of Medicine and Dentistry, University of Cologne, Cologne, Germany
Naturwissenschaften 95:367-82. 2008....
Attributing the burden of cancer at work: three areas of concern when examining the example of shift-workThomas C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Germany
Epidemiol Perspect Innov 8:4. 2011..Overall, causal, practical and methodological areas of concern should be diligently considered when performing and interpreting AF or BOD computations which - at least at the present time - may not be defensible...
Shift work, chronodisruption and cancer?--The IARC 2007 challenge for research and prevention and 10 theses from the Cologne Colloquium 2008Thomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Str 62, 50937 Koln, Germany
Scand J Work Environ Health 35:74-9. 2009..This overview summarizes the key ideas presented at the Cologne Colloquium and offers 10 theses concerning the need for targeted studies and the necessity to develop possible means of prevention...
Light Hygiene: Time to make preventive use of insights--old and new--into the nexus of the drug light, melatonin, clocks, chronodisruption and public healthThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Kerpener Strasse 62, 50937 Koln, Lindenthal, Germany
Med Hypotheses 73:537-41. 2009....
Research into the chronodisruption-cancer theory: the imperative for causal clarification and the danger of causal reductionismThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Kerpener Strasse 62, 50937 Koln, Lindenthal, Germany
Neuro Endocrinol Lett 31:1-3. 2010..Second, we emphasize the importance of considering the Zeitgeber multiplicity to avoid causal reductionism in epidemiologic - but also other - chronodisruption research...
Shift work and cancer: the evidence and the challengeThomas C Erren
Institut und Poliklinik für Arbeitsmedizin, Umweltmedizin und Präventionsforschung, Universitat zu Koln, Koln, Germany
Dtsch Arztebl Int 107:657-62. 2010..This review provides background and practical information with regard to the open question "does shift-work cause cancer?"..
Shift work, cancer and "white-box" epidemiology: Association and causationThomas C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research University of Cologne, Kerpener Straße 62, Haus 11 B, 50937 Koln, Germany
Epidemiol Perspect Innov 7:11. 2010..Sir Richard Doll 1...
Axelrod, the pineal and the melatonin hypothesis: lessons of 50 years to shape chronodisruption researchThomas C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Lindenthal, Germany
Neuro Endocrinol Lett 31:585-7. 2010....
Meta-analyses of published epidemiological studies, 1979-2006, point to open causal questions in silica-silicosis-lung cancer researchT C Erren
Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Germany
Med Lav 102:321-35. 2011..The objective was to examine in depth whether current data allows to answer the pressing question "does silica cause lung cancer in the absence of silicosis"?..
Clockwork blue: on the evolution of non-image-forming retinal photoreceptors in marine and terrestrial vertebratesT C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Kerpener Strasse 62, Koln, Lindenthal, Germany
Naturwissenschaften 95:273-9. 2008....
Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisitedT C Erren
Institut und Poliklinik für Arbeits und Sozialmedizin der Universität zu Köln, Cologne Lindenthal, Germany
Med Hypotheses 53:1-5. 1999..Since these observations are consistent with our corollary and the associated prediction, we suggest that research on a melatonin-inhibited carcinogenesis in the low-risk populations of the Arctic should be pursued...
The chronosense -- what light tells man about biological timeThomas C Erren
Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln, Lindenthal, Germany
Med Hypotheses 63:1074-80. 2004..We conclude that syndisciplinary research into the physiology and pathophysiological implications of the chronosense is warranted and summarize a series of research questions...
The quest for questions -- on the logical force of scienceThomas C Erren
Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry University of Cologne, Germany
Med Hypotheses 62:635-40. 2004..It is concluded that questions and hypotheses as their formal expression must be strongly encouraged: appropriate answers and crucial tests will ultimately follow...
Can fat explain the human brain's big bang evolution?-Horrobin's leads for comparative and functional genomicsT C Erren
Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln Lindenthal, Germany
Prostaglandins Leukot Essent Fatty Acids 70:345-7. 2004....
Light, timing of biological rhythms, and chronodisruption in manThomas C Erren
Institute and Polyclinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924, Cologne, Germany
Naturwissenschaften 90:485-94. 2003..We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention...
Preventive research and interventive research: in favour of to act rather than to reactT C Erren
Institut und Poliklinik für Arbeitsmedizin, Sozialmedizin und Sozialhygiene, Klinikum der Universität zu Köln, Joseph Stelzmann Strasse 9, 50924 Cologne Lindenthal, Germany
Med Hypotheses 59:215-22. 2002..Based also on conceptual considerations it is concluded that, while both research approaches are needed, a strategy with more emphasis on preventive research and taking action at an earlier stage may lead to more community success...
ELF-EMF, endocrine disruptors, light: what if we apply triage to research?T C Erren
Institut und Poliklinik für Arbeitsmedizin, Sozialmedizin und Sozialhygiene, Klinikum der Universität zu Köln, Joseph Stelzmann Strasse 9, 50924 Cologne Lindenthal, Germany
Med Hypotheses 59:212-4. 2002....
Does light cause internal cancers? The problem and challenge of an ubiquitous exposureThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Köln Lindenthal, Germany
Neuro Endocrinol Lett 23:61-70. 2002....
[Light, melatonin and internal cancers - recent facts and research perspectives]T C Erren
Institut und Poliklinik für Arbeits und Sozialmedizin, Klinikum der Universität zu Köln, Germany
Gesundheitswesen 64:278-83. 2002..Further epidemiological investigations can contribute to the understanding of the patho-physiological relationships between light, melatonin and human biology...
A meta-analysis of epidemiologic studies of electric and magnetic fields and breast cancer in women and menT C Erren
Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Germany
Bioelectromagnetics . 2001..The paramount methodological problem inhibiting valid conclusions about an association between EMF and breast cancer is the probable misclassification of exposure and the possible misclassification of the disease itself...
Could visible light contribute to the development of leukaemia and other cancers in children?Thomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Str 9, 50924 Köln, Lindenthal, Germany
Med Hypotheses 64:864-71. 2005..In fact, it could be much easier -- and much more effective -- to reevaluate and modify lighting systems than to manipulate other possible determinants of the chronic processes of cancer such as genetic, nutritional or lifestyle factors...
The case for a posteriori hypotheses to fuel scientific progressThomas C Erren
Institute and Policlinic for Occupational and Social Medicine, School of Medicine and Dentistry, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Köln, Lindenthal, Germany
Med Hypotheses 69:448-53. 2007..In this vein, a posteriori hypotheses should be encouraged as a thinker's prime tool rather than be discouraged. Indeed, it is suggested, that information on a posteriori hypotheses should be formally required when research is published...
Epigenetics: origins and implications for cancer epidemiologyMelissa S Nise
Institute and Policlinic for Occupational and Social Medicine, University of Cologne, Cologne Lindenthal, Germany
Med Hypotheses 74:377-82. 2010....
Urinary 6-sulfatoxymelatonin excretion in humans during domestic exposure to 50 hertz electromagnetic fieldsPierluigi Cocco
Department of Public Health, Occupational Health Section, University of Cagliari, Italy
Neuro Endocrinol Lett 26:136-42. 2005..We investigated the effects of residential exposure to ELF-EMF on the excretion of urinary 6-sulfatoxymelatonin (6-OHMS), the major melatonin metabolite, as an indicator of nocturnal melatonin secretion...
The long and thorny road to publication in quality journalsThomas C Erren
PLoS Comput Biol 3:e251. 2007
Prizes to solve problems in and beyond medicine, big and small: it can workThomas C Erren
Med Hypotheses 68:732-4. 2007..Provided that glittering prizes are offered and awarded with care, they can lead to effective problem-solving in medicine and related biomedical sciences as well...
Neanderthal, chimp and human genomes: hypotheses wanted for research into brain evolutionThomas C Erren
Med Hypotheses 70:4-7. 2008..Rather than pursuing black box genomics, we suggest that genetic analyses should be guided by hypotheses. One plausible candidate in this regard is the"fat-utilization" hypothesis proposed by the late David Horrobin...
Hamming's "open doors" and group creativity as keys to scientific excellence: the example of CambridgeThomas C Erren
Med Hypotheses 70:473-7. 2008....
Ten simple rules for a good poster presentationThomas C Erren
PLoS Comput Biol 3:e102. 2007
"Simple rules for editors"? Here is one rule to tackle neglected problems of publishingThomas C Erren
PLoS Comput Biol 3:e88; discussion e89. 2007
Ten simple rules for doing your best research, according to HammingThomas C Erren
PLoS Comput Biol 3:1839-40. 2007
Biologically based study of magnetic field exposure and female breast cancer--will there be a sensible interpretation without information on a likely culprit?Thomas C Erren
Epidemiology 14:129-30. 2003
Frog transparency led to discovery of melatoninThomas C Erren
Nature 451:127. 2008
Health clues from polar regionsThomas C Erren
Science 316:540. 2007
Results of rush to sequence genomes may be nonsenseThomas C Erren
Nature 452:151. 2008
Not all shifts are equal: it's time for comprehensive exposure metrics in chronodisruption researchThomas C Erren
Cancer Res 68:4011. 2008
Comparing Neanderthal and human genomesThomas C Erren
Science 315:1664; author reply 1664. 2007
Silica and lung cancerThomas C Erren
Epidemiology 18:521; author reply 521-2. 2007
