J Erdmann

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine II Cardiology, University of Regensburg, Regensburg, Germany
    Clin Genet 64:339-49. 2003
  2. ncbi KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction
    A Jeron
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    J Mol Cell Cardiol 36:287-93. 2004
  3. ncbi The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Mol Psychiatry 1:392-7. 1996
  4. ncbi Lack of association between polymorphisms of angiotensin II receptor genes and response to short-term angiotensin II infusion
    C Delles
    Department of Medicine and Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1573-8. 2000
  5. ncbi APOE alleles are not associated with calcific aortic stenosis
    J R Ortlepp
    Interdisciplinary Intermediate Care, University Hospital of Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
    Heart 92:1463-6. 2006
  6. ncbi Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine, Charite, Humboldt University and Deutsches Herzzentrum, Berlin, Germany
    J Am Coll Cardiol 38:322-30. 2001
  7. ncbi Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Hum Genet 97:614-9. 1996
  8. ncbi Robust association of the APOE epsilon4 allele with premature myocardial infarction especially in patients without hypercholesterolaemia: the Aachen study
    F Schmitz
    University Hospital of Aachen, Germany
    Eur J Clin Invest 37:106-8. 2007
  9. ncbi Well kept secrets of the genome
    H Schunkert
    Eur Heart J 24:501-3. 2003
  10. ncbi Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations: prediction of clinical status--is molecular genetics a new tool for the management of hypertrophic cardiomyopathy in clini
    C Hengstenberg
    Cardiovasc Res 57:298-301. 2003

Collaborators

Detail Information

Publications15

  1. ncbi Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine II Cardiology, University of Regensburg, Regensburg, Germany
    Clin Genet 64:339-49. 2003
    ..Systematic mutation screening in large samples of HCM patients leads to a genetic diagnosis in about 30% of unrelated index patients and in about 57% of patients with a positive family history...
  2. ncbi KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction
    A Jeron
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    J Mol Cell Cardiol 36:287-93. 2004
    ..Opening of the K(ATP) channel during ischemia results in action potential shortening in various studies and may therefore influence the outcome of AMI patients...
  3. ncbi The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Mol Psychiatry 1:392-7. 1996
    ..Our data suggests that genetic variation of the 5-HT7 receptor does not play a major role in the development of bipolar affective disorder and schizophrenia...
  4. ncbi Lack of association between polymorphisms of angiotensin II receptor genes and response to short-term angiotensin II infusion
    C Delles
    Department of Medicine and Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1573-8. 2000
    ..In this study, we examined the short-term effects of genetic polymorphisms of the angiotensin II AT1 - and AT2-receptor subtypes in humans by means of angiotensin II infusion...
  5. ncbi APOE alleles are not associated with calcific aortic stenosis
    J R Ortlepp
    Interdisciplinary Intermediate Care, University Hospital of Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
    Heart 92:1463-6. 2006
    ..To analyse the association of APOE alleles with aortic stenosis (AS) in a large study population...
  6. ncbi Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine, Charite, Humboldt University and Deutsches Herzzentrum, Berlin, Germany
    J Am Coll Cardiol 38:322-30. 2001
    ..We studied the clinical and genetic features of hypertrophic cardiomyopathy (HCM) caused by mutations in the myosin-binding protein C gene (MYBPC3) in 110 consecutive, unrelated patients and family members of European descent...
  7. ncbi Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Hum Genet 97:614-9. 1996
    ..However, the reported association of the non-coding polymorphism 102T/C with the disease has also been detected in our sample (P=0.041, odds ratio=1.28, 95% confidence interval 1.012-1.623)...
  8. ncbi Robust association of the APOE epsilon4 allele with premature myocardial infarction especially in patients without hypercholesterolaemia: the Aachen study
    F Schmitz
    University Hospital of Aachen, Germany
    Eur J Clin Invest 37:106-8. 2007
    ..From many candidate genes the APOE (apolipoprotein E) with the major alleles epsilon2/epsilon3/epsilon4 is in the focus of interest...
  9. ncbi Well kept secrets of the genome
    H Schunkert
    Eur Heart J 24:501-3. 2003
  10. ncbi Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations: prediction of clinical status--is molecular genetics a new tool for the management of hypertrophic cardiomyopathy in clini
    C Hengstenberg
    Cardiovasc Res 57:298-301. 2003
  11. ncbi Aldosterone synthase (CYP11B2) -344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension
    C Delles
    Department of Medicine/Nephrology, University of Erlangen, , Germany
    J Am Coll Cardiol 37:878-84. 2001
    ..Differences in renal sodium handling across the genotypes might contribute to this finding...
  12. ncbi Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans
    R E Schmieder
    Department of Medicine IV Nephrology, University of Erlangen Nurnberg, Germany
    J Am Coll Cardiol 37:175-82. 2001
    ..Our study goal was to analyze whether gene variants of angiotensin II type 2-receptor (AT2-R) modulate the effects of angiotensin II on the left ventricle (LV)...
  13. ncbi Functional gene testing of the Glu298Asp polymorphism of the endothelial NO synthase
    M P Schneider
    Department of Medicine Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1767-73. 2000
    ..To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation...
  14. ncbi Genetic variants in the promoter (g983G>T) and coding region (A92T) of the human cardiotrophin-1 gene (CTF1) in patients with dilated cardiomyopathy
    J Erdmann
    Department of Internal Medicine and Cardiology, Charit, CVK, Humboldt University Berlin and Deutsches Herzzentrum Berlin, Germany
    Hum Mutat 16:448. 2000
  15. ncbi [Congestive heart failure is a common disease with complex inheritance--new perspectives through genome wide association studies]
    P Linsel-Nitschke
    Medizinische Klinik II, Universitat zu Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Internist (Berl) 49:405-10, 412. 2008
    ..This review article will focus on congestive heart failure as a complex trait and will discuss the impact of new technology (genome wide association studies) on the elucidation of common genetic risk factors for congestive heart failure...