J Erdmann

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine II Cardiology, University of Regensburg, Regensburg, Germany
    Clin Genet 64:339-49. 2003
  2. ncbi request reprint KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction
    A Jeron
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    J Mol Cell Cardiol 36:287-93. 2004
  3. ncbi request reprint The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Mol Psychiatry 1:392-7. 1996
  4. ncbi request reprint Lack of association between polymorphisms of angiotensin II receptor genes and response to short-term angiotensin II infusion
    C Delles
    Department of Medicine and Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1573-8. 2000
  5. pmc APOE alleles are not associated with calcific aortic stenosis
    J R Ortlepp
    Interdisciplinary Intermediate Care, University Hospital of Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
    Heart 92:1463-6. 2006
  6. ncbi request reprint Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine, Charite, Humboldt University and Deutsches Herzzentrum, Berlin, Germany
    J Am Coll Cardiol 38:322-30. 2001
  7. ncbi request reprint Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Hum Genet 97:614-9. 1996
  8. ncbi request reprint Robust association of the APOE epsilon4 allele with premature myocardial infarction especially in patients without hypercholesterolaemia: the Aachen study
    F Schmitz
    University Hospital of Aachen, Germany
    Eur J Clin Invest 37:106-8. 2007
  9. ncbi request reprint Well kept secrets of the genome
    H Schunkert
    Eur Heart J 24:501-3. 2003
  10. ncbi request reprint Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations: prediction of clinical status--is molecular genetics a new tool for the management of hypertrophic cardiomyopathy in clini
    C Hengstenberg
    Cardiovasc Res 57:298-301. 2003

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine II Cardiology, University of Regensburg, Regensburg, Germany
    Clin Genet 64:339-49. 2003
    ..Systematic mutation screening in large samples of HCM patients leads to a genetic diagnosis in about 30% of unrelated index patients and in about 57% of patients with a positive family history...
  2. ncbi request reprint KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction
    A Jeron
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    J Mol Cell Cardiol 36:287-93. 2004
    ..Opening of the K(ATP) channel during ischemia results in action potential shortening in various studies and may therefore influence the outcome of AMI patients...
  3. ncbi request reprint The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Mol Psychiatry 1:392-7. 1996
    ..Our data suggests that genetic variation of the 5-HT7 receptor does not play a major role in the development of bipolar affective disorder and schizophrenia...
  4. ncbi request reprint Lack of association between polymorphisms of angiotensin II receptor genes and response to short-term angiotensin II infusion
    C Delles
    Department of Medicine and Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1573-8. 2000
    ..In this study, we examined the short-term effects of genetic polymorphisms of the angiotensin II AT1 - and AT2-receptor subtypes in humans by means of angiotensin II infusion...
  5. pmc APOE alleles are not associated with calcific aortic stenosis
    J R Ortlepp
    Interdisciplinary Intermediate Care, University Hospital of Aachen, Pauwelsstrasse 30, D 52057 Aachen, Germany
    Heart 92:1463-6. 2006
    ..To analyse the association of APOE alleles with aortic stenosis (AS) in a large study population...
  6. ncbi request reprint Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
    J Erdmann
    Department of Internal Medicine, Charite, Humboldt University and Deutsches Herzzentrum, Berlin, Germany
    J Am Coll Cardiol 38:322-30. 2001
    ..We studied the clinical and genetic features of hypertrophic cardiomyopathy (HCM) caused by mutations in the myosin-binding protein C gene (MYBPC3) in 110 consecutive, unrelated patients and family members of European descent...
  7. ncbi request reprint Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia
    J Erdmann
    Institute of Human Genetics, University of Bonn, Germany
    Hum Genet 97:614-9. 1996
    ..However, the reported association of the non-coding polymorphism 102T/C with the disease has also been detected in our sample (P=0.041, odds ratio=1.28, 95% confidence interval 1.012-1.623)...
  8. ncbi request reprint Robust association of the APOE epsilon4 allele with premature myocardial infarction especially in patients without hypercholesterolaemia: the Aachen study
    F Schmitz
    University Hospital of Aachen, Germany
    Eur J Clin Invest 37:106-8. 2007
    ..From many candidate genes the APOE (apolipoprotein E) with the major alleles epsilon2/epsilon3/epsilon4 is in the focus of interest...
  9. ncbi request reprint Well kept secrets of the genome
    H Schunkert
    Eur Heart J 24:501-3. 2003
  10. ncbi request reprint Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations: prediction of clinical status--is molecular genetics a new tool for the management of hypertrophic cardiomyopathy in clini
    C Hengstenberg
    Cardiovasc Res 57:298-301. 2003
  11. ncbi request reprint Aldosterone synthase (CYP11B2) -344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension
    C Delles
    Department of Medicine/Nephrology, University of Erlangen, , Germany
    J Am Coll Cardiol 37:878-84. 2001
    ..Differences in renal sodium handling across the genotypes might contribute to this finding...
  12. ncbi request reprint Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans
    R E Schmieder
    Department of Medicine IV Nephrology, University of Erlangen Nurnberg, Germany
    J Am Coll Cardiol 37:175-82. 2001
    ..Our study goal was to analyze whether gene variants of angiotensin II type 2-receptor (AT2-R) modulate the effects of angiotensin II on the left ventricle (LV)...
  13. ncbi request reprint Functional gene testing of the Glu298Asp polymorphism of the endothelial NO synthase
    M P Schneider
    Department of Medicine Nephrology, University of Erlangen Nurnberg, Germany
    J Hypertens 18:1767-73. 2000
    ..To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation...
  14. ncbi request reprint Genetic variants in the promoter (g983G>T) and coding region (A92T) of the human cardiotrophin-1 gene (CTF1) in patients with dilated cardiomyopathy
    J Erdmann
    Department of Internal Medicine and Cardiology, Charite, CVK, Humboldt University Berlin and Deutsches Herzzentrum Berlin, Germany
    Hum Mutat 16:448. 2000
  15. doi request reprint [Congestive heart failure is a common disease with complex inheritance--new perspectives through genome wide association studies]
    P Linsel-Nitschke
    Medizinische Klinik II, Universitat zu Lubeck, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Internist (Berl) 49:405-10, 412. 2008
    ..This review article will focus on congestive heart failure as a complex trait and will discuss the impact of new technology (genome wide association studies) on the elucidation of common genetic risk factors for congestive heart failure...