T Engelhorn

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint What is effective in malignant middle cerebral artery infarction: reperfusion, craniectomy, or both? An experimental study in rats
    T Engelhorn
    Department of Neuroradiology, University of Essen, Germany
    Stroke 33:617-22. 2002
  2. ncbi request reprint Multilocal magnetic resonance perfusion mapping comparing the cerebral hemodynamic effects of decompressive craniectomy versus reperfusion in experimental acute hemispheric stroke in rats
    T Engelhorn
    Department of Neuroradiology, Essen University School of Medicine, Hufelandstrasse 55, D 45122 Essen, Germany
    Neurosci Lett 344:127-31. 2003
  3. ncbi request reprint Transcortical or transcallosal approach to ventricle-associated lesions: a clinical study on the prognostic role of surgical approach
    Siamak Asgari
    Department of Neurosurgery, University Hospital of Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Neurosurg Rev 26:192-7. 2003
  4. ncbi request reprint Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats
    Tobias Engelhorn
    Department of Neuroradiology, University of Erlangen, School of Medicine, Schwabachanlage 6, D 91054 Erlangen, Germany
    Neurosci Lett 406:92-6. 2006
  5. ncbi request reprint 1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG
    Thilo Hammen
    Center Epilepsy Erlangen, Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Epilepsia 48:263-9. 2007
  6. ncbi request reprint Decompressive craniectomy in acute cerebral ischemia in rats. Is there any benefit in smaller thromboembolic infarcts?
    Tobias Engelhorn
    Department of Neuroradiology, University of Essen, School of Medicine, Hufelandstrasse 55, D 45122 Essen, Germany
    Neurosci Lett 370:85-90. 2004
  7. ncbi request reprint The angiotensin II type 1-receptor blocker candesartan increases cerebral blood flow, reduces infarct size, and improves neurologic outcome after transient cerebral ischemia in rats
    Tobias Engelhorn
    Department of Neuroradiology, Essen University, Essen, Germany
    J Cereb Blood Flow Metab 24:467-74. 2004
  8. ncbi request reprint Feasibility of cerebral blood volume mapping by flat panel detector CT in the angiography suite: first experience in patients with acute middle cerebral artery occlusions
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuernberg, Erlangen, Germany
    AJNR Am J Neuroradiol 33:618-25. 2012
  9. ncbi request reprint Flat detector CT in the evaluation of brain parenchyma, intracranial vasculature, and cerebral blood volume: a pilot study in patients with acute symptoms of cerebral ischemia
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    AJNR Am J Neuroradiol 31:1462-9. 2010
  10. ncbi request reprint Monitoring of acute generalized status epilepticus using multilocal diffusion MR imaging: early prediction of regional neuronal damage
    T Engelhorn
    Department of Neuroradiology, University of Erlangen, Erlangen, Germany
    AJNR Am J Neuroradiol 28:321-7. 2007

Detail Information

Publications31

  1. ncbi request reprint What is effective in malignant middle cerebral artery infarction: reperfusion, craniectomy, or both? An experimental study in rats
    T Engelhorn
    Department of Neuroradiology, University of Essen, Germany
    Stroke 33:617-22. 2002
    ..We sought to evaluate the effects of reperfusion and craniectomy treatment at different time points after middle cerebral artery (MCA) occlusion on infarct volume and neurological outcome in MCA infarction in rats...
  2. ncbi request reprint Multilocal magnetic resonance perfusion mapping comparing the cerebral hemodynamic effects of decompressive craniectomy versus reperfusion in experimental acute hemispheric stroke in rats
    T Engelhorn
    Department of Neuroradiology, Essen University School of Medicine, Hufelandstrasse 55, D 45122 Essen, Germany
    Neurosci Lett 344:127-31. 2003
    ..PWI is well suited to non-invasively monitor perfusion alterations after aggressive therapeutical approaches in stroke...
  3. ncbi request reprint Transcortical or transcallosal approach to ventricle-associated lesions: a clinical study on the prognostic role of surgical approach
    Siamak Asgari
    Department of Neurosurgery, University Hospital of Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Neurosurg Rev 26:192-7. 2003
    ..Additionally, the incidence of postoperative seizures and subdural fluid collections after transcortical surgery is high...
  4. ncbi request reprint Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats
    Tobias Engelhorn
    Department of Neuroradiology, University of Erlangen, School of Medicine, Schwabachanlage 6, D 91054 Erlangen, Germany
    Neurosci Lett 406:92-6. 2006
    ..Combined treatment was superior to rosuvastatin alone, but not to candesartan. The therapeutic benefit of both agents was at least in parts mediated by eNOS-activation...
  5. ncbi request reprint 1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG
    Thilo Hammen
    Center Epilepsy Erlangen, Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Epilepsia 48:263-9. 2007
    ..In this study, hippocampal metabolite alterations in (1)H-MR spectroscopy ((1)H-MRS) were correlated to the findings of intensive video-EEG monitoring and duration of seizure symptoms in patients with temporal lobe epilepsy (TLE)...
  6. ncbi request reprint Decompressive craniectomy in acute cerebral ischemia in rats. Is there any benefit in smaller thromboembolic infarcts?
    Tobias Engelhorn
    Department of Neuroradiology, University of Essen, School of Medicine, Hufelandstrasse 55, D 45122 Essen, Germany
    Neurosci Lett 370:85-90. 2004
    ..3 mm3 and 82.7 +/- 21.5 mm3, respectively. There was no significant difference between the two groups (P > 0.79). In conclusion, our results demonstrate that for small thromboembolic MCA infarction early craniectomy is not beneficial...
  7. ncbi request reprint The angiotensin II type 1-receptor blocker candesartan increases cerebral blood flow, reduces infarct size, and improves neurologic outcome after transient cerebral ischemia in rats
    Tobias Engelhorn
    Department of Neuroradiology, Essen University, Essen, Germany
    J Cereb Blood Flow Metab 24:467-74. 2004
    ..Apart from pretreatment, other treatment regimens result in significantly improved neuroscores. In the acute phase of cerebral ischemia, candesartan increases CBF...
  8. ncbi request reprint Feasibility of cerebral blood volume mapping by flat panel detector CT in the angiography suite: first experience in patients with acute middle cerebral artery occlusions
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuernberg, Erlangen, Germany
    AJNR Am J Neuroradiol 33:618-25. 2012
    ..We tested the hypothesis that findings in FPCT CBV and FPCT would correlate with those obtained using MSCT and PCT...
  9. ncbi request reprint Flat detector CT in the evaluation of brain parenchyma, intracranial vasculature, and cerebral blood volume: a pilot study in patients with acute symptoms of cerebral ischemia
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    AJNR Am J Neuroradiol 31:1462-9. 2010
    ..We tested the hypothesis that when used in conjunction with IV contrast, FD-CT imaging would provide both anatomic and physiologic information that would correlate well with that obtained by using standard multisection CT techniques...
  10. ncbi request reprint Monitoring of acute generalized status epilepticus using multilocal diffusion MR imaging: early prediction of regional neuronal damage
    T Engelhorn
    Department of Neuroradiology, University of Erlangen, Erlangen, Germany
    AJNR Am J Neuroradiol 28:321-7. 2007
    ..The aim of this study was to investigate the evolution of acute phase changes in different brain regions during experimental status epilepticus (SE) using DWI correlated with SE-induced neuronal cell loss...
  11. ncbi request reprint MR contrast agents in acute experimental cerebral ischemia: potential adverse impacts on neurologic outcome and infarction size
    A Doerfler
    Department of Neuroradiology, University of Essen Medical School, D 45122 Essen, Germany
    J Magn Reson Imaging 11:418-24. 2000
    ....
  12. ncbi request reprint Flat panel detector angiographic CT in the management of aneurysmal rupture during coil embolization
    T Engelhorn
    Department of Neuroradiology, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    AJNR Am J Neuroradiol 29:1581-4. 2008
    ..Additionally, ACT revealed pronounced rebleeding within the time between conventional CT and onset of treatment. In the management of aneurysmal rupture during coil embolization, ACT may be a valuable adjunct...
  13. ncbi request reprint Monitoring of balloon test occlusion of the internal carotid artery by parametric color coding and perfusion imaging within the angio suite: first results
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuermberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Clin Neuroradiol 23:285-92. 2013
    ....
  14. ncbi request reprint Combination of decompressive craniectomy and mild hypothermia ameliorates infarction volume after permanent focal ischemia in rats
    A Doerfler
    Department of Neuroradiology, University of Essen, Germany
    Stroke 32:2675-81. 2001
    ..This study was designed to evaluate the effect of combined DC and hypothermia on infarction size and neurological outcome in a rat model of MCA occlusion (MCAO)...
  15. doi request reprint Flat-panel detector volumetric CT for visualization of subarachnoid hemorrhage and ventricles: preliminary results compared to conventional CT
    M Doelken
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Neuroradiology 50:517-23. 2008
    ..The aim of this study was to compare flat-panel volumetric CT (VCT) to conventional CT (cCT) in the visualization of the extent of subarachnoid hemorrhage (SAH) and the width of the ventricles in patients with acute SAH...
  16. ncbi request reprint Early diffusion-weighted MRI predicts regional neuronal damage in generalized status epilepticus in rats treated with diazepam
    T Engelhorn
    Department of Neuroradiology, University of Erlangen, Erlangen, Germany
    Neurosci Lett 417:275-80. 2007
    ..Using ADC-mapping, verification of early anticonvulsive therapy in SE seems to be possible as there is good correlation between the maximal decrease in ACD in the acute phase of SE and late neuronal cell loss...
  17. ncbi request reprint Cerebral perfusion alterations during the acute phase of experimental generalized status epilepticus: prediction of survival by using perfusion-weighted MR imaging and histopathology
    T Engelhorn
    Department of Neuroradiology, University of Essen, Germany
    AJNR Am J Neuroradiol 26:1563-70. 2005
    ..Because perfusion-weighted MR imaging (PWI) allows noninvasive CP-determination, the aim of this study was to investigate CP alterations during acute experimental SE correlated with SE-induced neuronal cell loss...
  18. ncbi request reprint Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients
    I E Sandalcioglu
    Department of Neurosurgery, University of Essen, Essen, Germany
    Spinal Cord 43:34-41. 2005
    ..To analyze factors with impact on the functional outcome for patients with surgically treated intramedullary spinal cord tumors (IMSCT) and to point out characteristics of the different histological entities...
  19. ncbi request reprint (1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy
    M T Doelken
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Seizure 17:490-7. 2008
    ....
  20. ncbi request reprint Endovascular treatment of middle cerebral artery aneurysms with electrolytically detachable coils
    A Doerfler
    Department of Neuroradiology, University of Essen Medical School, Essen, Germany
    AJNR Am J Neuroradiol 27:513-20. 2006
    ..Our purpose was to analyze the feasibility, safety, and efficacy of coil embolization in a consecutive series of MCA aneurysms chosen for endovascular treatment...
  21. ncbi request reprint Fibromyxoma of the iliac wing
    C A Kuhne
    Department of Traumatology, University of Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Skeletal Radiol 32:170-3. 2003
    ..Final diagnosis by radiological characteristics was not conclusive and histopathological examination suggested the diagnosis of a myxoma/fibromyxoma...
  22. ncbi request reprint Angiographic C-arm CT visualization of the Woven EndoBridge cerebral aneurysm embolization device (WEB): first experience in an animal aneurysm model
    T Struffert
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Clin Neuroradiol 24:43-9. 2014
    ..Our hypothesis was that the imaging of these implants C-arm CT would provide useful information regarding their positioning and deployment...
  23. ncbi request reprint Flat panel detector angiographic CT for stent-assisted coil embolization of broad-based cerebral aneurysms
    G Richter
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    AJNR Am J Neuroradiol 28:1902-8. 2007
    ..The purpose of this work was to evaluate angiographic CT (ACT) in the combined application of a self-expanding neurovascular stent and detachable platinum coils in the management of broad-based and fusiform intracranial aneurysms...
  24. doi request reprint Visualization and monitoring of acute epistaxis during endovascular treatment using a flat detector CT
    S Ott
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    Minim Invasive Neurosurg 54:187-90. 2011
    ..Then the suspected bleeding point is treated by endovascular embolization based on the clinical suspicion...
  25. ncbi request reprint Intra-operative characterization of gliomas by near-infrared spectroscopy: possible association with prognosis
    S Asgari
    Department of Neurosurgery, University Hospital, Essen, Germany
    Acta Neurochir (Wien) 145:453-59; discussion 459-60. 2003
    ....
  26. ncbi request reprint Surgical prognosis in hindbrain related syringomyelia
    S Asgari
    Department of Neurosurgery, University Hospital Essen, Hufelandstr 55, Essen, Germany
    Acta Neurol Scand 107:12-21. 2003
    ..The recommended operative treatment against hindbrain related syringomyelia is suboccipital decompression. The aim of the study was to define prognostic factors for surgical outcome in this disease...
  27. ncbi request reprint Perfusion- and diffusion-weighted magnetic resonance imaging for monitoring decompressive craniectomy in animals with experimental hemispheric stroke
    Arnd Doerfler
    Department of Neuroradiology, University of Essen Medical School, Germany
    J Neurosurg 96:933-40. 2002
    ..The aim of this study was to use two types of serial magnetic resonance (MR) imaging-perfusion-weighted (PW) and diffusion-weighted (DW)-to monitor craniectomy in rats with hemispheric stroke...
  28. ncbi request reprint Does a relative perfusion measure predict cerebral infarct size?
    Tobias Engelhorn
    Department of Neuroradiology, University Hospital, Erlangen, Germany
    AJNR Am J Neuroradiol 26:2218-23. 2005
    ..The present study tested whether a relative measure of cerebral blood flow such as is obtained with PWI is sufficient to predict irreversible tissue damage following focal cerebral ischemia and reperfusion in the rat suture model...
  29. ncbi request reprint Intramedullary spinal cord cavernous malformations: clinical features and risk of hemorrhage
    Ibrahim Erol Sandalcioglu
    Department of Neurosurgery, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Neurosurg Rev 26:253-6. 2003
    ..Based on the significant risk of rehemorrhage and the gratifying functional results, surgery is indicated for symptomatic IMSC cavernous malformations...
  30. ncbi request reprint Intraoperative measurement of cortical oxygen saturation and blood volume adjacent to cerebral arteriovenous malformations using near-infrared spectroscopy
    Siamak Asgari
    Department of Neurosurgery, University Hospital, Hufelandstrasse 55, 45147 Essen, Germany
    Neurosurgery 52:1298-304; discussion 1304-6. 2003
    ..Among a series of patients with cerebral arteriovenous malformations, we examined the problem of hyperemia after embolization/resection or resection with the intraoperative application of near-infrared spectroscopy...
  31. ncbi request reprint Impaired resting perfusion in viable myocardium distal to chronic coronary stenosis in rats
    Christiane Waller
    Universit├Ątsklinik W├╝rzburg, Medizinische Klinik, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Am J Physiol Heart Circ Physiol 288:H2588-93. 2005
    ..05). These results indicate that resting perfusion in viable poststenotic myocardium is moderately reduced. Alterations in global and regional LV function are therefore secondary to both patchy fibrosis and reduced resting perfusion...