S A Eming

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Efficacy and safety of the freeze-dried cultured human keratinocyte lysate, LyphoDerm 0.9%, in the treatment of hard-to-heal venous leg ulcers
    Keith G Harding
    Department of Surgery, Wound Healing Research Unit, University of Wales, College of Medicine, Cardiff, United Kingdom
    Wound Repair Regen 13:138-47. 2005
  2. pmc A case of linear porokeratosis superimposed on disseminated superficial actinic porokeratosis
    Rebecca Löhrer
    Department of Dermatology, University of Cologne, Cologne, Germany
    Case Rep Dermatol 2:130-4. 2010
  3. ncbi request reprint Interrelation of immunity and tissue repair or regeneration
    Sabine A Eming
    Department of Dermatology, University of Cologne, Germany
    Semin Cell Dev Biol 20:517-27. 2009
  4. pmc Accelerated wound closure in mice deficient for interleukin-10
    Sabine A Eming
    Department of Dermatology, University of Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Am J Pathol 170:188-202. 2007
  5. ncbi request reprint Inflammation in wound repair: molecular and cellular mechanisms
    Sabine A Eming
    Department of Dermatology, University of Cologne, Cologne, Germany
    J Invest Dermatol 127:514-25. 2007
  6. doi request reprint Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds
    Sabine A Eming
    Department of Dermatology, Center for Molecular Medicine Cologne CMMC, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases CECAD, Institute for Oral and Musculoskeletal Biology, University of Cologne, Cologne, Germany
    J Proteome Res 9:4758-66. 2010
  7. ncbi request reprint Regulation of angiogenesis: wound healing as a model
    Sabine A Eming
    Department of Dermatology, University of Cologne, Joseph Stelzmann Street 9, 50931 Koln, Germany
    Prog Histochem Cytochem 42:115-70. 2007
  8. ncbi request reprint Gene transfer in tissue repair: status, challenges and future directions
    Sabine A Eming
    University of Cologne, Department of Dermatology, Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Expert Opin Biol Ther 4:1373-86. 2004
  9. ncbi request reprint Increased expression of VEGF in glomeruloid reactive angioendotheliomatosis
    Sabine A Eming
    Department of Dermatology, University of Cologne, Cologne, Germany
    Dermatology 207:398-401. 2003
  10. ncbi request reprint [Chronic wounds. Novel approaches in research and therapy]
    S A Eming
    Klinik und Poliklinik fur Dermatologie und Venerologie, Universitat zu Koln, Joseph Stelzmann Strasse 9, 50931 Koln
    Hautarzt 58:939-44. 2007

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Efficacy and safety of the freeze-dried cultured human keratinocyte lysate, LyphoDerm 0.9%, in the treatment of hard-to-heal venous leg ulcers
    Keith G Harding
    Department of Surgery, Wound Healing Research Unit, University of Wales, College of Medicine, Cardiff, United Kingdom
    Wound Repair Regen 13:138-47. 2005
    ....
  2. pmc A case of linear porokeratosis superimposed on disseminated superficial actinic porokeratosis
    Rebecca Löhrer
    Department of Dermatology, University of Cologne, Cologne, Germany
    Case Rep Dermatol 2:130-4. 2010
    ..Molecular analysis of cases of type 2 segmental involvement may help elucidate the genetic defect causing DSAP...
  3. ncbi request reprint Interrelation of immunity and tissue repair or regeneration
    Sabine A Eming
    Department of Dermatology, University of Cologne, Germany
    Semin Cell Dev Biol 20:517-27. 2009
    ..Finally, we report on new mechanistic insights on how these inflammatory pathways impair healing under pathological conditions and discuss therapeutic implications...
  4. pmc Accelerated wound closure in mice deficient for interleukin-10
    Sabine A Eming
    Department of Dermatology, University of Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Am J Pathol 170:188-202. 2007
    ..These results show for the first time that IL-10 can impede wound repair...
  5. ncbi request reprint Inflammation in wound repair: molecular and cellular mechanisms
    Sabine A Eming
    Department of Dermatology, University of Cologne, Cologne, Germany
    J Invest Dermatol 127:514-25. 2007
    ..In this paper, we review cellular and molecular mechanisms controlling inflammation in cutaneous tissue repair and provide a rationale for targeting the inflammatory phase in order to modulate the outcome of the healing response...
  6. doi request reprint Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds
    Sabine A Eming
    Department of Dermatology, Center for Molecular Medicine Cologne CMMC, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases CECAD, Institute for Oral and Musculoskeletal Biology, University of Cologne, Cologne, Germany
    J Proteome Res 9:4758-66. 2010
    ..This analysis therefore represents an important basis for the search for potential biomarkers, which give rise to a better understanding and monitoring of disease progression in chronic wounds...
  7. ncbi request reprint Regulation of angiogenesis: wound healing as a model
    Sabine A Eming
    Department of Dermatology, University of Cologne, Joseph Stelzmann Street 9, 50931 Koln, Germany
    Prog Histochem Cytochem 42:115-70. 2007
    ..The article provides a rationale for targeting the angiogenic response in order to modulate the outcome of the healing response...
  8. ncbi request reprint Gene transfer in tissue repair: status, challenges and future directions
    Sabine A Eming
    University of Cologne, Department of Dermatology, Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Expert Opin Biol Ther 4:1373-86. 2004
    ..This article summarises repair mechanisms and their failure, and gives an overview of techniques and studies applied to gene transfer in tissue repair. It also provides perspectives on potential targets for gene transfer technology...
  9. ncbi request reprint Increased expression of VEGF in glomeruloid reactive angioendotheliomatosis
    Sabine A Eming
    Department of Dermatology, University of Cologne, Cologne, Germany
    Dermatology 207:398-401. 2003
    ..This case suggests a possible role of epidermally derived VEGF in endothelial cell proliferation in RAE...
  10. ncbi request reprint [Chronic wounds. Novel approaches in research and therapy]
    S A Eming
    Klinik und Poliklinik fur Dermatologie und Venerologie, Universitat zu Koln, Joseph Stelzmann Strasse 9, 50931 Koln
    Hautarzt 58:939-44. 2007
    ..This review focuses on new developments in wound healing research and the resulting non-operative therapeutic implications...
  11. doi request reprint Extracellular matrix in angiogenesis: dynamic structures with translational potential
    Sabine A Eming
    Department of Dermatology, University of Cologne, Koln, Germany
    Exp Dermatol 20:605-13. 2011
    ..Finally, this article will provide a rationale for targeting the ECM-morphogen interplay for therapeutic angiogenesis...
  12. ncbi request reprint Molecular mechanisms of VEGF-A action during tissue repair
    Sabine A Eming
    Department of Dermatology, University of Cologne, Cologne, Germany
    J Investig Dermatol Symp Proc 11:79-86. 2006
    ..These observations support the concept that VEGF-A and VEGF-A receptors are important mediators in tissue repair. Further, our data provide mechanisms how VEGF-A-mediated interactions are disturbed during impaired healing...
  13. pmc Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair
    Detlev Roth
    Department of Dermatology, University of Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Am J Pathol 168:670-84. 2006
    ..Inactivation of the plasmin cleavage site Arg110/Ala111 may preserve the biological function of VEGF165 in therapeutic angiogenesis under conditions in which proteases are highly active, such as wound repair and inflammation...
  14. ncbi request reprint Generation of a novel proteolysis resistant vascular endothelial growth factor165 variant by a site-directed mutation at the plasmin sensitive cleavage site
    Gereon Lauer
    Department of Dermatology, University of Cologne, Cologne, Germany
    FEBS Lett 531:309-13. 2002
    ..These results suggest that the plasmin cleavage site Arg110/Ala111 and the carboxyl-terminal domain play an important role in the mitogenic activity of VEGF165...
  15. doi request reprint [Autoinflammatory diseases as cause of wound healing defects]
    R Lohrer
    Klinik und Poliklinik fur Dermatologie und Venerologie, Universitat zu Koln, Kerpenerstr 62, 50937, Koln, Deutschland
    Hautarzt 62:524-33. 2011
    ..Furthermore, the article will be complemented by an overview of those inflammatory diseases that are associated with non-ulcerative cutaneous manifestations...
  16. pmc Alternative proteolytic processing of hepatocyte growth factor during wound repair
    Nils Buchstein
    Professor of Dermatology, Department of Dermatology, University of Cologne, Joseph Stelzmann Str 9, 50931 Koln, Germany
    Am J Pathol 174:2116-28. 2009
    ....
  17. doi request reprint Differential roles of macrophages in diverse phases of skin repair
    Tina Lucas
    Department of Dermatology, University of Cologne, Cologne, Germany
    J Immunol 184:3964-77. 2010
    ..These results demonstrate that macrophages exert distinct functions during the diverse phases of skin repair, which are crucial to control the natural sequence of repair events...
  18. pmc Gene therapy and wound healing
    Sabine A Eming
    Department of Dermatology, University of Cologne, D 50937 Cologne, Germany
    Clin Dermatol 25:79-92. 2007
    ..We have summarized the molecular and cellular basis of repair mechanisms and their failure, and we give an overview of techniques and studies applied to gene transfer in tissue repair...
  19. ncbi request reprint Treatment of chronic wounds: state of the art and future concepts
    Sabine A Eming
    Department of Dermatology, University of Cologne, Germany
    Cells Tissues Organs 172:105-17. 2002
    ....
  20. ncbi request reprint [Delayed wound healing during therapy of cutaneous graft-versus-host disease with everolimus]
    A Brown
    Klinik und Poliklinik fur Dermatologie und Venerologie, Uniklinik Köln, Kerpener Str 62, 50937, Koln, Deutschland
    Hautarzt 65:553-5. 2014
    ..We describe a patient with chronic cutaneous GvHD who developed massive skin ulcerations after changing the immunosuppressive therapy to a mammalian target of rapamycin (mTOR)-inhibitor. ..
  21. ncbi request reprint A novel property of povidon-iodine: inhibition of excessive protease levels in chronic non-healing wounds
    Sabine A Eming
    J Invest Dermatol 126:2731-3. 2006
  22. pmc The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms
    Athanasios N Athanasopoulos
    Experimental Immunology Branch, NCI, NIH, Center Dr, Rm 4B17, Bethesda, MD 20892, USA
    Blood 107:2720-7. 2006
    ..Eap may also serve as a lead compound for new anti-inflammatory and antiangiogenic therapies in several pathologies...
  23. ncbi request reprint Particle-mediated gene therapy of wounds
    Jeffrey M Davidson
    Department of Pathology, Vanderbilt University School of Medicine, Department of Veterans Affairs Medical Center, Nashville, TN, USA
    Methods Mol Med 78:433-52. 2003
  24. ncbi request reprint Increased levels of the soluble variant of the vascular endothelial growth factor receptor VEGFR-1 are associated with a poor prognosis in wound healing
    Sabine A Eming
    J Invest Dermatol 123:799-802. 2004