Osman El-Maarri

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. El Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz Lacava A, et al. Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles. PLoS ONE. 2011;6:e16252 pubmed publisher
    ..In conclusion, neither natural cycle of hormones nor age has a detectable effect on the LINE-1 methylation in peripheral blood cells, while gender remains an important factor. ..
  2. request reprint
    El Maarri O, Singer H, Klein C, Watzka M, Herbiniaux U, Brackmann H, et al. Lack of F8 mRNA: a novel mechanism leading to hemophilia A. Blood. 2006;107:2759-65 pubmed
    ..These findings strongly suggest that the cause of HA in this patient is either absence or rapid degradation of the F8 mRNA, which points to a novel mechanism leading to HA. ..
  3. El Maarri O, Kareta M, Mikeska T, Becker T, Diaz Lacava A, Junen J, et al. A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum Mol Genet. 2009;18:1755-68 pubmed publisher
    ....

Detail Information

Publications3

  1. El Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz Lacava A, et al. Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles. PLoS ONE. 2011;6:e16252 pubmed publisher
    ..In conclusion, neither natural cycle of hormones nor age has a detectable effect on the LINE-1 methylation in peripheral blood cells, while gender remains an important factor. ..
  2. request reprint
    El Maarri O, Singer H, Klein C, Watzka M, Herbiniaux U, Brackmann H, et al. Lack of F8 mRNA: a novel mechanism leading to hemophilia A. Blood. 2006;107:2759-65 pubmed
    ..These findings strongly suggest that the cause of HA in this patient is either absence or rapid degradation of the F8 mRNA, which points to a novel mechanism leading to HA. ..
  3. El Maarri O, Kareta M, Mikeska T, Becker T, Diaz Lacava A, Junen J, et al. A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum Mol Genet. 2009;18:1755-68 pubmed publisher
    ....