D Eissner

Summary

Affiliation: University of Mainz
Country: Germany

Publications

  1. ncbi Occupancy of striatal D(2)-like dopamine receptors after treatment with the sigma ligand EMD 57445, a putative atypical antipsychotic
    G Grunder
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, D 55131 Mainz, Germany
    Psychopharmacology (Berl) 146:81-6. 1999
  2. ncbi [18F]Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors
    G Grunder
    Department of Psychiatry, University of Mainz, Germany
    Eur J Nucl Med 28:1463-70. 2001
  3. ncbi [Which properties make a neuroleptic "atypical"?]
    G Grunder
    Psychiatrische Klinik und Poliklinik, Universitat Mainz, Untere Zahlbacher Strasse 8, 55131 Mainz
    Nervenarzt 72:833-43. 2001
  4. ncbi Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride
    Gerhard Grunder
    Department of Psychiatry, University of Mainz, Mainz, Germany
    J Nucl Med 44:109-16. 2003
  5. ncbi Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo
    Gerhard Grunder
    Department of Psychiatry, University of Mainz, Germany
    Neuropsychopharmacology 28:787-94. 2003
  6. ncbi [The next generation of "atypical" antipsychotics: the role of positron emission tomography]
    G Grunder
    Psychiatrische Klinik und Poliklinik, Universitat Mainz, Germany
    Fortschr Neurol Psychiatr 71:415-20. 2003
  7. ncbi Regional cerebral blood flow in depression: associations with psychopathology
    S Schlegel
    Department of Psychiatry, University of Mainz, F R G
    J Affect Disord 17:211-8. 1989

Detail Information

Publications7

  1. ncbi Occupancy of striatal D(2)-like dopamine receptors after treatment with the sigma ligand EMD 57445, a putative atypical antipsychotic
    G Grunder
    Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, D 55131 Mainz, Germany
    Psychopharmacology (Berl) 146:81-6. 1999
    ..It has been reported recently to have antipsychotic activity in schizophrenia. However, its metabolite, EMD 59983, binds also to D(2) and D(3) dopamine (DA) receptors...
  2. ncbi [18F]Fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors
    G Grunder
    Department of Psychiatry, University of Mainz, Germany
    Eur J Nucl Med 28:1463-70. 2001
    ....
  3. ncbi [Which properties make a neuroleptic "atypical"?]
    G Grunder
    Psychiatrische Klinik und Poliklinik, Universitat Mainz, Untere Zahlbacher Strasse 8, 55131 Mainz
    Nervenarzt 72:833-43. 2001
    ..A variety of biological mechanisms characterizes a heterogeneous group of substances, which also substantially differ in their clinical properties...
  4. ncbi Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride
    Gerhard Grunder
    Department of Psychiatry, University of Mainz, Mainz, Germany
    J Nucl Med 44:109-16. 2003
    ..18)F-Desmethoxyfallypride ((18)F-DMFP) is a benzamide tracer with the advantage of an (18)F label. We optimized the synthesis and evaluated (18)F-DMFP in PET studies on healthy human volunteers...
  5. ncbi Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo
    Gerhard Grunder
    Department of Psychiatry, University of Mainz, Germany
    Neuropsychopharmacology 28:787-94. 2003
    ..We link an alteration in cerebral catecholamine metabolism in human brain with the therapeutic action of neuroleptic medication...
  6. ncbi [The next generation of "atypical" antipsychotics: the role of positron emission tomography]
    G Grunder
    Psychiatrische Klinik und Poliklinik, Universitat Mainz, Germany
    Fortschr Neurol Psychiatr 71:415-20. 2003
    ..PET like no other method is suitable to display in vivo a novel mechanism of "atypicality" of a new class of antipsychotics...
  7. ncbi Regional cerebral blood flow in depression: associations with psychopathology
    S Schlegel
    Department of Psychiatry, University of Mainz, F R G
    J Affect Disord 17:211-8. 1989
    ..Patients with 'reactive' features had higher CBF than patients without 'reactive' symptoms. Only patients without 'reactive' symptoms had a lower CBF than controls. 'Endogenous' features had no impact on CBF...