Wolfgang Driever


Affiliation: University of Freiburg
Country: Germany


  1. Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W. A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis. Dev Biol. 2014;385:433-47 pubmed publisher
    ..We discuss mechanistic implications of simultaneous activation of transcriptional targets by ubiquitous, like Pou5f1, and region-specific inducers, emerging as a common regulatory motif in early development. ..
  2. Driever W. Developmental Biology: Reissner's Fiber and Straightening of the Body Axis. Curr Biol. 2018;28:R833-R835 pubmed publisher
    ..New research demonstrates that Reissner's fiber, an enigmatic structure within the spinal central canal, is essential for development of an extended trunk to tail axis. ..
  3. Reinig S, Driever W, Arrenberg A. The Descending Diencephalic Dopamine System Is Tuned to Sensory Stimuli. Curr Biol. 2017;27:318-333 pubmed publisher
    ..Together with the adjacent hypothalamic neurons, they may serve to set basic behavioral states. ..
  4. Schredelseker T, Driever W. Bsx controls pineal complex development. Development. 2018;145: pubmed publisher
    ..Several genes involved in rod-like or cone-like phototransduction are also abnormally expressed, indicating that Bsx has a pivotal role in the differentiation of multiple cell types in the zebrafish pineal complex. ..
  5. Onichtchouk D, Driever W. Zygotic Genome Activators, Developmental Timing, and Pluripotency. Curr Top Dev Biol. 2016;116:273-97 pubmed publisher
    ..We review the current knowledge of the roles of these genes in developing vertebrate embryos from fish to mammals and suggest a model for pluripotency gene regulatory network functions in early development. ..
  6. Eckerle S, Ringler M, Lecaudey V, Nitschke R, Driever W. Progesterone modulates microtubule dynamics and epiboly progression during zebrafish gastrulation. Dev Biol. 2018;434:249-266 pubmed publisher
    ..Progesterone may thus act as a non-cell-autonomous regulator of microtubule dynamics across the large yolk cell, and may adjust differing demands on microtubule dynamics and stability during initiation and progression phases of epiboly. ..
  7. Filippi A, Durr K, Ryu S, Willaredt M, Holzschuh J, Driever W. Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and noradrenergic neuronal development. BMC Dev Biol. 2007;7:135 pubmed
    ..A di-mesencephalic longitudinal domain of lmx1b expression may be the basis for the expansion and posterior shift of ventral di-/mesencephalic dopaminergic populations with ascending projections during evolution. ..
  8. Mahler J, Driever W. Expression of the zebrafish intermediate neurofilament Nestin in the developing nervous system and in neural proliferation zones at postembryonic stages. BMC Dev Biol. 2007;7:89 pubmed
  9. request reprint
    Driever W. The bicoid morphogen papers (II): account from Wolfgang Driever. Cell. 2004;116:S7-9, 2 p following S9 pubmed

More Information


  1. Driever W. A Cue for Driving Large-Scale Cell Movement. Dev Cell. 2016;37:201-2 pubmed publisher
    ..Reporting in Developmental Cell, Szabó et al. (2016) uncover a mechanism for morphogenesis based on complement system C3a/C3aR-directed chemotaxis. ..