Research Topics
| Adrian DraguSummaryAffiliation: University of Erlangen-Nuremberg Country: Germany Publications
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Detail Information
Publications
Evaluation of intra-operative abdominal wall perfusion in post-bariatric abdominal dermolipectomyAdrian Dragu
Department of Plastic and Hand Surgery, University Hospital, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
Obes Facts 5:651-9. 2012..Little is known about the regional perfusion patterns before and after post-bariatric abdominal dermolipectomy. This study focuses on assessment of intraoperative micro-perfusion patterns of the abdominal tissue...
Immunohistochemical evaluation after ex vivo perfusion of rectus abdominis muscle flaps in a porcine modelAdrian Dragu
Department of Plastic and Hand Surgery, Institute of Pathology, Friedrich Alexander University of Erlangen Nurnberg, University Hospital, Erlangen, Germany
Plast Reconstr Surg 130:265e-273e. 2012....
Online oxygen measurements in ex vivo perfused muscle tissue in a porcine model using dynamic quenching methodsAdrian Dragu
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen Nurnberg, University Hospital, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 132:655-61. 2012..Tissue--and in particular muscle tissue--is strongly sensitive to ischemia, thus after a critical period of oxygen depletion the risk of a partial or total flap loss is high...
Pseudotumors after primary abdominal lipectomy as a new sequela in patients with abdominal apronAdrian Dragu
Department of Plastic and Hand Surgery, University Clinic, University of Erlangen Nurnberg, Krankenhausstrasse 12, 91054 Erlangen, Germany
Obes Surg 19:1599-604. 2009..So far no common standard and long-term effectiveness is proven. In addition, there is no sufficient literature dealing with the postoperative risks of plication of the musculoaponeurotic wall...
Intrapulmonary and cutaneous siliconomas after silent silicone breast implant failureAdrian Dragu
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, University Hospital, 91054 Erlangen, Germany
Breast J 15:496-9. 2009....
[Commentary on the article of P. S. Harenberg and D. Erdmann: academic plastic surgery: a comparison of residency models in Germany and the USA]A Dragu
Klinik für Plastische und Handchirurgie, Universitätsklinikum Erlangen Nürnberg, Erlangen
Handchir Mikrochir Plast Chir 41:371-3. 2009..Nevertheless, further corrections are necessary. In the end only competent and well qualified board certified plastic surgeons are in the position to represent this specific field of surgery on a skilled and a political basis...
Expression of HIF-1α in ischemia and reperfusion in human microsurgical free muscle tissue transferAdrian Dragu
Department of Plastic and Hand Surgery, Nikolaus Fiebiger Center of Molecular Medicine, Friedrich Alexander University of Erlangen Nurnberg, University Hospital, Erlangen, Germany
Plast Reconstr Surg 127:2293-300. 2011..The aim of this study was to analyze the expression of hypoxia-inducible factor (HIF)-1α during ischemia and after reperfusion in muscle tissue in the context of microsurgical free muscle tissue transfer...
Scars and perforator-based flaps in the abdominal region: a contraindication?Adrian Dragu
Department of Plastic and Hand Surgery, University of Erlangen Nürnberg Medical Center, 91054 Erlangen, Germany
Can J Surg 53:137-42. 2010..To date, little research has been conducted on the regeneration potential of the abdominal wall's superficial vascular, perforator and choke vessel system after surgery using a vertical approache...
Gene expression analysis of ischaemia and reperfusion in human microsurgical free muscle tissue transferAdrian Dragu
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen Nurnberg, University Hospital, Erlangen, Germany
J Cell Mol Med 15:983-93. 2011..When inflammatory and apoptotic proteins are expressed at high levels, flap damage might occur and flap loss is likely. The sole expression on mRNA level might explain why flap loss is unlikely...
Wide topical negative pressure wound dressing treatment for patients undergoing abdominal dermolipectomy following massive weight lossAdrian Dragu
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen Nurnberg, University Hospital, Krankenhausstrasse 12, 91054, Erlangen, Germany
Obes Surg 21:1781-6. 2011....
Standards and interdisciplinary treatment of boxing injuries of the head in professional boxing on the basis of an IBF World Championship FightAdrian Dragu
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen Nurnberg, Medical Center, Erlangen, Germany
Med Sci Monit 16:CS149-52. 2010..A realistic short term aim would be to develop a national standard in order to unify the management and medical treatment of boxing injuries in professional boxing...
Extracorporeal perfusion of free muscle flaps in a porcine model using a miniaturized perfusion systemAdrian Dragu
Department of Plastic and Hand Surgery, University Hospital, Friedrich Alexander University of Erlangen Nurnberg, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 131:849-55. 2011....
Tensiometry as a decision tool for abdominal wall reconstruction with component separationAdrian Dragu
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, Medical Center, Krankenhausstrasse 12, 91054, Erlangen, Germany
World J Surg 33:1174-80. 2009..A number of authors even recommended separating the lateral components of the abdominal wall to preserve innervation and blood supply of the advanced parts...
Bilateral obstetric brachial plexus paralysis: a case reportA Dragu
Department of Plastic and Hand Surgery, University Hospital, University of Erlangen Nurnberg, Erlangen, Germany
Klin Padiatr 221:57-9. 2009....
[Forequarter amputation of the right upper chest: limitations of ultra radical interdisciplinary oncological surgery]A Dragu
Klinik für Plastische und Handchirurgie, Universitatsklinikum, Friedrich Alexander Universitat Erlangen Nurnberg, Deutschland
Chirurg 82:834-8. 2011..The English full-text version of this article is available at SpringerLink (under "Supplemental")...
Foreign body reaction after usage of tissue adhesives for skin closure: a case report and review of the literatureAdrian Dragu
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, University Clinic, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 129:167-9. 2009..However, so far the risks and possible complications after using 2-octyl cyanoacrylate are not sufficiently published and discussed...
Acute and diffuse postoperative bleeding after free latissimus dorsi flap--Factor XIII deficiency: a case report and review of the literatureAdrian Dragu
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, University Hospital, Erlangen, Germany
Med Sci Monit 15:CS1-4. 2009..This again leads to the wrong indication such as revision with the aim to find a surgical origin of bleeding. Instead a haematological deficiency such as Factor XIII is the reason for acute postoperative bleeding and haemorrhage...
Expression of leptin, leptin receptor, and connective tissue growth factor in degenerative disk lesions in the wristFrank Unglaub
Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
Arthroscopy 27:755-60. 2011..The purpose of this study was to identify whether leptin and connective tissue growth factor (CTGF) occur in the degenerative fibrocartilage disk and whether cartilage cells express leptin receptors...
Transverse cervical artery perforator propeller flap for reconstruction of supraclavicular defectsUlrich Kneser
Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Krankenhausstrasse 12, D 91054 Erlangen, Germany
J Plast Reconstr Aesthet Surg 64:952-4. 2011..This technique should be considered as an alternative to commonly used muscle or myocutanous flaps in selected cases...
Subjective outcome, neurophysiological investigations, postoperative complications and recurrence rate of partial medial epicondylectomy in cubital tunnel syndromeSaskia M Schnabl
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Krankenhausstrasse 12, Erlangen, Germany
Arch Orthop Trauma Surg 131:1027-33. 2011..2 m/s postoperatively. One patient developed a haematoma and three patients (10.3%) had to be classified as recurrence. High postoperative rates of patient satisfaction and improved neurophysiological results could be achieved by pME...
Decision-making in DIEP and ms-TRAM flaps: the potential role for a combined laser Doppler spectrophotometry systemJustus P Beier
Department of Plastic and Hand Surgery, University Hospital of Erlangen, Friedrich Alexander University of Erlangen Nurnberg, Krankenhausstr 12, 91054 Erlangen, Germany
J Plast Reconstr Aesthet Surg 66:73-9. 2013..In this study, a combined lased Doppler spectrophotometry (CLDS) system was applied intra-operatively to support the surgeon's decision-making process...
Expression of TRAIL and death receptor DR4 in Palmer type 2 TFCC lesionsFrank Unglaub
Department of Plastic and Hand Surgery, University Erlangen, Krankenhausstrasse 12, Erlangen, Germany
Arch Orthop Trauma Surg 130:1215-20. 2010..Apoptosis has been found to play a crucial role in fibrocartilage cell loss, however, the molecular mechanism and mediators are still poorly understood...
Double pedicled perforator flap to close flank defects: an alternative for closure of a large lumbar defect after basalioma excision--a case report and review of the literatureGunther Arco
Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Erlangen, Germany
Ann Plast Surg 63:422-4. 2009..The skin defect after excision was reconstructed using a novel concept based on 2 independent pedicled perforator flaps, a lumbar artery perforator, and a lateral intercostal artery perforator...
Cartilage cell proliferation in degenerative TFCC wrist lesionsFrank Unglaub
Department of Plastic and Hand Surgery, University Erlangen, Germany
Arch Orthop Trauma Surg 130:953-6. 2010..The central zone of the triangular fibrocartilage complex (TFCC) of the wrist is thought to be avascular and is generally considered to lack any healing potential...
Coverage of exposed bones and joints in critically ill patients: lower extremity salvage with topical negative pressure therapyRaymund E Horch
Department of Plastic and Hand Surgery, Institute of Radiology, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen, Germany
J Cutan Med Surg 12:223-9. 2008..A potential treatment with topical negative pressure may allow split-thickness skin grafting to the bone, which leads to limb salvage...
Acute postoperative infection with Aeromonas hydrophila after using medical leeches for treatment of venous congestionSaskia M Schnabl
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Krankenhausstrasse 12, Erlangen, Germany
Arch Orthop Trauma Surg 130:1323-8. 2010..The potential risks such as infections associated with leech therapy are generally underestimated and not sufficiently discussed in literature...
Directly auto-transplanted mesenchymal stem cells induce bone formation in a ceramic bone substitute in an ectopic sheep modelAnja M Boos
Department of Plastic and Hand Surgery, University Hospital of Erlangen, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
J Cell Mol Med 15:1364-78. 2011..Hence BMP-2 stimulation might become dispensable in the future, thus providing an attractive, clinically feasible approach to bone tissue engineering...
Nerve fiber staining investigations in traumatic and degenerative disc lesions of the wristFrank Unglaub
Department of Plastic and Hand Surgery, University Erlangen, Erlangen, Germany
J Hand Surg Am 36:843-6. 2011..We hypothesized that an ingrowth of nerve fibers causes ulnar-sided wrist pain associated with traumatic and degenerative disc lesions...
Aesthetic and functional correction of female, asymmetric funnel chest - a combined approachJustus P Beier
Department of Plastic and Hand Surgery, University Hospital of Erlangen, Erlangen, Germany
Breast 18:60-5. 2009..In conclusion we recommend correction of female asymmetric funnel chest by primary sternal reduction with secondary breast augmentation during metal plate removal 1 year after...
Factors influencing successful outcome in the arteriovenous loop model: a retrospective study of 612 loop operationsElias Polykandriotis
Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
J Reconstr Microsurg 27:11-8. 2011..Experience and practice are both significant predictors of successful outcome. Possible applications of the model for research purposes are discussed...
Incidence and distribution of blood vessels in punch biopsies of Palmer 1A disc lesions in the wristFrank Unglaub
Department of Plastic and Hand Surgery, University Erlangen, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 129:631-4. 2009..In addition, the study investigated if arthroscopic debridement can reach vascularized tissue to enable a reparative response of the tear...
Apoptotic pathways in degenerative disk lesions in the wristFrank Unglaub
Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
Arthroscopy 25:1380-6. 2009..We also investigated whether ulna length played an etiologic role in the occurrence of fibrocartilage cell loss...
Myocutaneous propeller flap based on the superior gluteal artery (SGA) for closure of large lumbosacral meningomyelocoele defects: a case reportVolker J Schmidt
Plastisch und Handchirurgische Klinik, Universitatsklinikum Erlangen, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen, Germany
J Plast Reconstr Aesthet Surg 65:521-4. 2012..The technique is reliable and straightforward and requires no skin grafts or relaxing incisions. The SGA-based myocutaneous propeller flap might be a promising alternative for complex meningomyelocoele reconstructions in the future...
Phlegmonous-infection in first degree Dupuytren's diseaseFrank Unglaub
Department of Plastic and Hand Surgery, University of Erlangen, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 129:445-8. 2009....
Comparison between distally based peroneus brevis and sural flaps for reconstruction of foot, ankle and distal lower leg: an analysis of donor-site morbidity and clinical outcomeUlrich Kneser
Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Krankenhausstrasse 12, D 91054 Erlangen, Germany
J Plast Reconstr Aesthet Surg 64:656-62. 2011..We aimed to compare functional outcome and donor-site morbidity following transfer of distally based delayed sural (DSFs) or peroneus brevis flaps (PBFs)...
Changes of anabolic processes at the cellular and molecular level in chronic wounds under topical negative pressure can be revealed by transcriptome analysisMareike Leffler
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, Medical Center, Krankenhausstrasse 12, Erlangen, Germany
J Cell Mol Med 15:1564-71. 2011....
Malignant Natural-Killer cell neoplasm presenting as a mucous cyst on the distal interphalangeal joint of the fingerFrank Unglaub
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Germany
Arch Orthop Trauma Surg 129:1613-6. 2009..The analysis revealed the presence of a Natural-Killer cell neoplasm. This case illustrates and stresses the importance of a pathohistological examination when doubts arise about the initial diagnosis of a benign tumorous lesion...
Reconstruction of a child's forefoot defect using a distally based pedicled medial plantar flapFrank Unglaub
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Germany
Arch Orthop Trauma Surg 130:155-8. 2010..Use of this particular kind of flap proves advantageous in that it provides good protection in the weight-bearing area of the foot, while causing only a minor donor site defect...
Perineal and vaginal wall reconstruction using a combined inferior gluteal and pudendal artery perforator flap: a case reportVolker J Schmidt
Department of Plastic and Hand Surgery, Erlangen University Hospital, Krankenhausstr 12, 91054 Erlangen, Germany
J Plast Reconstr Aesthet Surg 65:1734-7. 2012....
Tc-99m Sestamibi SPECT/CT as a New Tool for Monitoring Perfusion and Viability of Buried Perforator Based Free Flaps in Breast Reconstruction After Breast CancerAdrian Dragu
From the Department of Plastic and Hand Surgery, , University Hospital, Erlangen, Germany daggerClinic of Nuclear Medicine, , University Hospital, Erlangen, Germany and double daggerDivision of Molecular and Experimental Surgery, Department of Surgery, , University Hospital, Erlangen, Germany
Clin Nucl Med 35:36-7. 2010..The results confirmed the intraoperative clinical findings. Tc-99m-sestamibi-SPECT/CT may be a new tool for the postoperative evaluation of regional perfusion and viability of buried perforator based free flaps...
[Kienböck's disease. Diagnosis and therapy]R E Horch
Klinik für Plastische und Handchirurgie, Friedrich Alexander Universitat Erlangen Nurnberg, Krankenhausstrasse 12, 91054 Erlangen
Chirurg 79:452-60. 2008..Treatment methods extend from immobilization to revascularization surgery on the affected bone. There is still no gold standard for the treatment of Kienböck's disease...
Regression and persistence: remodelling in a tissue engineered axial vascular assemblyE Polykandriotis
Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
J Cell Mol Med 13:4166-75. 2009..Phenomena of remodelling were evaluated quantitatively in a neovascular network and variance could be proposed as a parameter of net vascular maturation...
Aplasia cutis congenita--plastic reconstruction of three scalp and skull defects with two opposed scalp rotation flaps and split thickness skin graftingS M Schnabl
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Erlangen, Germany
Neuropediatrics 40:134-6. 2009..We report on the successful treatment of three large defects of the scalp with skull involvement in a newborn girl by early debridement and defect closure with two opposed scalp rotation flaps and an occipital split-thickness skin graft...
[Economic aspects of surgical wound therapies]R E Horch
Plastische und Handchirurgische Klinik, Universitatsklinikum Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Deutschland
Chirurg 79:518-25. 2008..Health care insurers in Germany pay 5 billion Euros annually in materials alone for pressure ulcers, diabetic foot ulcers, and ulcus cruris. With such figures it is necessary to consider, economic aspects of treatment...
The use of the artificial dermis (Integra) in combination with vacuum assisted closure for reconstruction of an extensive burn scar--a case reportM Leffler
Department of Plastic and Hand Surgery, University Hospital Erlangen, Krankenhausstrasse 12, D 91054 Erlangen, Germany
J Plast Reconstr Aesthet Surg 63:e32-5. 2010..Hospital stay was shortened because the patient could be treated as an outpatient with an ambulant vacuum assisted closure device...
Objective outcome of partial medial epicondylectomy in cubital tunnel syndromeSaskia M Schnabl
Department of Plastic and Hand Surgery, Friedrich Alexander University of Erlangen, Krankenhausstrasse 12, 91054, Erlangen, Germany
Arch Orthop Trauma Surg 130:1549-56. 2010..Goal of the study was to evaluate the clinical outcome in cubital tunnel syndrome (CuTS) after partial medial epicondylectomy (pME) with objective parameters...
Bilateral atypical muscles causing acute bilateral carpal tunnel syndrome in recreational climberFrank Unglaub
Department of Plastic and Hand Surgery, University of Erlangen, Krankenhausstrasse 12, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 130:37-40. 2010..This case report describes the highly unusual case of the occurrence of bilateral flexor digitorum superficialis muscles in a recreational climber who developed CTS following his intensive training schedule...
An unusual case of gonococcal arthritis of the fingerSusanne B Thomas
Department of Plastic and Hand Surgery, University Erlangen, 91054 Erlangen, Germany
Arch Orthop Trauma Surg 129:1335-8. 2009..In this article, we describe the unexpected finding of septic arthritis in the proximal interphalangeal joint of a 50-year-old patient. The septic arthritis was caused by N. gonorrhoeae...
Radial collateral ligament repair of the thumb metacarpophalangeal joint using the abductor pollicis brevis tendonRaymund E Horch
Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Erlangen, Germany
Plast Reconstr Surg 117:491-6. 2006..The key concept is to reestablish joint stability by spanning the tendinous portion of the insertion of the abductor pollicis brevis over the radial side of the metacarpophalangeal joint...
Solving acne inversa (hidradenitis suppurativa) in Crohn disease with buried chip skin graftsOliver Bleiziffer
Department of Plastic and Hand Surgery, University of Erlangen Nurnberg, Medical Center, Erlangen, Germany
J Cutan Med Surg 13:164-8. 2009..Common treatment strategies of reconstructive surgery such as local flaps, free flaps, or split-thickness skin grafts are frequently problematic and associated with poor outcomes...
