Katharina Domschke

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:667-73. 2007
  2. ncbi Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women
    Katharina Domschke
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 7:183-8. 2004
  3. ncbi Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48143 Muenster, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:224-8. 2008
  4. doi Association of MAO-A variant with complicated grief in major depression
    Anette Kersting
    Department of Psychiatry, University of Munster, Munster, Germany
    Neuropsychobiology 56:191-6. 2007
  5. pmc Coincidence of paroxysmal supraventricular tachycardia and panic disorder: two case reports
    Katharina Domschke
    Department of Psychiatry, , , Germany
    Ann Gen Psychiatry 9:13. 2010
  6. pmc Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
    P F Sullivan
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Mol Psychiatry 14:359-75. 2009
  7. pmc Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain
    Bernhard T Baune
    Discipline of Psychiatry, School of Medicine, University of Adelaide, North Terrace, Adelaide, South Australia, Australia
    J Neuroinflammation 9:125. 2012
  8. pmc ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 37:759-69. 2012
  9. doi Interoceptive sensitivity in anxiety and anxiety disorders: an overview and integration of neurobiological findings
    Katharina Domschke
    Department of Psychiatry and Psychotherapy, University of Munster, Albert Schweitzer Strasse 11, D 48149 Munster, Germany
    Clin Psychol Rev 30:1-11. 2010
  10. doi Blushing propensity in social anxiety disorder: influence of serotonin transporter gene variation
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, 48149 Muenster, Germany
    J Neural Transm 116:663-6. 2009

Detail Information

Publications64

  1. ncbi Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:667-73. 2007
    ....
  2. ncbi Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women
    Katharina Domschke
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 7:183-8. 2004
    ..Our data support a role of the 472G/A (V158M) COMT polymorphism or a nearby locus in the pathogenesis of panic disorder in women...
  3. ncbi Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48143 Muenster, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 32:224-8. 2008
    ....
  4. doi Association of MAO-A variant with complicated grief in major depression
    Anette Kersting
    Department of Psychiatry, University of Munster, Munster, Germany
    Neuropsychobiology 56:191-6. 2007
    ..Therefore, in the present study, genetic variation in the MAO-A gene was investigated for its influence on complicated grief in major depression...
  5. pmc Coincidence of paroxysmal supraventricular tachycardia and panic disorder: two case reports
    Katharina Domschke
    Department of Psychiatry, , , Germany
    Ann Gen Psychiatry 9:13. 2010
    ..As both PSVT and PD require different treatments, potentially helpful differential clinical diagnostic criteria are proposed...
  6. pmc Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
    P F Sullivan
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Mol Psychiatry 14:359-75. 2009
    ..With the integrated replication effort, we present a specific hypothesis for further studies...
  7. pmc Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain
    Bernhard T Baune
    Discipline of Psychiatry, School of Medicine, University of Adelaide, North Terrace, Adelaide, South Australia, Australia
    J Neuroinflammation 9:125. 2012
    ..Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes. In this study the potential dual role of several IL-6 polymorphisms in brain morphology is investigated...
  8. pmc ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 37:759-69. 2012
    ..The present findings may eventually aid in improving primary and secondary prevention by sharpening the risk profiles of anxiety-prone individuals...
  9. doi Interoceptive sensitivity in anxiety and anxiety disorders: an overview and integration of neurobiological findings
    Katharina Domschke
    Department of Psychiatry and Psychotherapy, University of Munster, Albert Schweitzer Strasse 11, D 48149 Munster, Germany
    Clin Psychol Rev 30:1-11. 2010
    ....
  10. doi Blushing propensity in social anxiety disorder: influence of serotonin transporter gene variation
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, 48149 Muenster, Germany
    J Neural Transm 116:663-6. 2009
    ....
  11. ncbi Imaging genetics of anxiety disorders
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48149 Muenster, Germany
    Neuroimage 53:822-31. 2010
    ....
  12. ncbi Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:510-6. 2008
    ..However, in order to allow for conclusive evaluation of the present finding and to exclude a false positive result, further studies in larger, independent, preferably family based samples are warranted...
  13. ncbi Neuropeptide Y (NPY) gene: Impact on emotional processing and treatment response in anxious depression
    Katharina Domschke
    Dept of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 20:301-9. 2010
    ..The present results point towards a possible influence of functional NPY gene variation on antidepressant treatment response in anxious depression, potentially conveyed by altered emotional processing...
  14. doi Neuropeptide S receptor gene -- converging evidence for a role in panic disorder
    K Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Mol Psychiatry 16:938-48. 2011
    ..The present results provide converging evidence for a female-dominant role of NPSR gene variation in panic disorder potentially through heightened autonomic arousal and distorted processing of anxiety-relevant emotional stimuli...
  15. doi Dysbindin (DTNBP1)--a role in psychotic depression?
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, D 48143 Muenster, Germany
    J Psychiatr Res 45:588-95. 2011
    ....
  16. ncbi Genetics
    Katharina Domschke
    Department of Psychiatry, University of Munster, Albert Schweitzer Strasse 11, 48149, Munster, Germany
    Curr Top Behav Neurosci 2:63-75. 2010
    ..The pathomechanism of anxiety disorders and in particular panic disorder is considered to be multifactorial with converging evidence for a pivotal role of genetic factors in particular, which will be presented in detail in this chapter...
  17. doi COMT val158met influence on electroconvulsive therapy response in major depression
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:286-90. 2010
    ....
  18. doi Influence of the catechol-O-methyltransferase val158met genotype on amygdala and prefrontal cortex emotional processing in panic disorder
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Albert Schweitzer Str 11, D 48143 Muenster, Germany
    Psychiatry Res 163:13-20. 2008
    ..This COMT variant might increase the vulnerability to panic disorder by modulating dopaminergic tonus in relevant brain regions and thus altering neuronal processing of anxiety-related emotional cues...
  19. ncbi Altered auditory processing in patients with panic disorder: a pilot study
    Bettina Pfleiderer
    Department of Clinical Radiology, University of Muenster, Muenster, Germany pfl
    World J Biol Psychiatry 11:945-55. 2010
    ..Thus, habituation of neuronal activation after repeated sine tone stimulation was assessed by functional magnetic resonance imaging (fMRI) in patients with PD...
  20. doi Reduced amygdala-prefrontal coupling in major depression: association with MAOA genotype and illness severity
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 12:11-22. 2009
    ..We conclude that genetic variation in the MAOA gene may affect the course of major depression by disrupting cortico-limbic connectivity...
  21. doi Norepinephrine and serotonin transporter genes: impact on treatment response in depression
    Anna Baffa
    Department of Psychiatry, University of Munster, Munster, Germany
    Neuropsychobiology 62:121-31. 2010
    ....
  22. doi Effect of gender on processing threat-related stimuli in patients with panic disorder: sex does matter
    Patricia Ohrmann
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Depress Anxiety 27:1034-43. 2010
    ..g. panic disorder (PD)...
  23. ncbi Cannabinoid receptor 1 (CNR1) gene: impact on antidepressant treatment response and emotion processing in major depression
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 18:751-9. 2008
    ..This analysis provides preliminary support for a role of CNR1 gene variation in depression and anxiety, potentially mediated by subcortical hypo-responsiveness to social reward stimuli...
  24. ncbi Association analysis of Rgs7 variants with panic disorder
    Christa Hohoff
    Department of Psychiatry, University of Muenster, Muenster, Germany
    J Neural Transm 116:1523-8. 2009
    ..Our results argue against a major role of Rgs7 gene variants in the pathogenesis of PD, but are consistent with a minor gender-specific effect on PD, particularly PDAgP...
  25. ncbi Dopamine D₃ receptor gene variation: impact on electroconvulsive therapy response and ventral striatum responsiveness in depression
    Udo Dannlowski
    Department of Psychiatry, University of Muenster, Germany
    Int J Neuropsychopharmacol 16:1443-59. 2013
    ..002; sample 2: p=0.023). In summary, the present study suggests some impact of DRD3 gene variation on ECT response, potentially mediated by alteration of striatal engagement during the processing of emotionally rewarding stimuli...
  26. ncbi Association of the COMT val158met variant with antidepressant treatment response in major depression
    Bernhard T Baune
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 33:924-32. 2008
    ..This finding suggests a potentially beneficial effect of an antidepressive add-on therapy with substances increasing dopamine availability individually tailored according to COMT val158met genotype...
  27. doi Effects of ADORA2A gene variation and caffeine on prepulse inhibition: a multi-level risk model of anxiety
    Agnieszka Gajewska
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, D 97080 Wuerzburg, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 40:115-21. 2013
    ....
  28. doi Catechol-O-methyltransferase gene variation: impact on amygdala response to aversive stimuli
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany
    Neuroimage 60:2222-9. 2012
    ....
  29. ncbi Acute anxiolytic effects of quetiapine during virtual reality exposure--a double-blind placebo-controlled trial in patients with specific phobia
    Julia Diemer
    Department of Psychiatry, University of Muenster, Germany
    Eur Neuropsychopharmacol 23:1551-60. 2013
    ..The present results thus suggest a possible suitability of quetiapine in the acute treatment of anxiety, particularly with regard to somatic symptoms. ..
  30. doi Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations
    Andreas Reif
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Am J Med Genet B Neuropsychiatr Genet 159:786-93. 2012
    ..However, epigenetic mechanisms might obfuscate the genetic association, calling for ascertainment in larger samples as well as assessment of the MAOA promoter methylation status therein...
  31. doi Adenosine A(2A) receptor gene: evidence for association of risk variants with panic disorder and anxious personality
    Christa Hohoff
    Department of Psychiatry, University of Muenster, Albert Schweitzer Strasse 11, 48149 Muenster, Germany
    J Psychiatr Res 44:930-7. 2010
    ..Our data provide further support for an important role of ADORA2A variants in the pathogenesis of anxiety disorders and anxious personality reflecting their potential as basic susceptibility factors...
  32. ncbi Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Albert Schweitzer Strasse 11, Munster, Germany
    Biol Psychiatry 71:286-93. 2012
    ....
  33. ncbi Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Albert Schweitzer Str 11, 48149 Munster, Germany
    Neuroimage 53:893-8. 2010
    ..We conclude that 5-HTTLPR genotype predominantly impacts the central processing predominantly of negative environmental cues but not of emotionally salient stimuli in general...
  34. pmc Acute shift in glutamate concentrations following experimentally induced panic with cholecystokinin tetrapeptide--a 3T-MRS study in healthy subjects
    Peter Zwanzger
    Mood and Anxiety Disorders Research Unit, Department of Psychiatry and Psychotherapy, University of Muenster, Muenster, Germany
    Neuropsychopharmacology 38:1648-54. 2013
    ....
  35. doi Epigenetic signature of panic disorder: a role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany Department of Psychiatry, University of Wuerzburg, Germany Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:189-96. 2013
    ..Future studies are warranted to replicate the present finding in independent samples, preferably in a longitudinal design. ..
  36. ncbi Monoamine oxidase A gene DNA hypomethylation - a risk factor for panic disorder?
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany
    Int J Neuropsychopharmacol 15:1217-28. 2012
    ..Future studies are warranted to replicate the present finding in independent samples, preferably in a longitudinal design...
  37. pmc Gender differences in associations of glutamate decarboxylase 1 gene (GAD1) variants with panic disorder
    Heike Weber
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    PLoS ONE 7:e37651. 2012
    ..In a recent association study in depression, which is highly comorbid with panic disorder, GAD1 risk allele associations were restricted to females...
  38. doi Modification of caffeine effects on the affect-modulated startle by neuropeptide S receptor gene variation
    Katharina Domschke
    Department of Psychiatry and Psychotherapy, University of Muenster, Albert Schweitzer Campus 1, Gebaeude A9, 48149 Muenster, Germany
    Psychopharmacology (Berl) 222:533-41. 2012
    ..2006) and attenuating the stimulatory effects of NPS in rodents (Boeck et al., 2010)...
  39. pmc Neuropeptide-S (NPS) receptor genotype modulates basolateral amygdala responsiveness to aversive stimuli
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Munster, Germany
    Neuropsychopharmacology 36:1879-85. 2011
    ..Thereby, NPSR rs324981 apparently causes an indirect effect on anxiety-related traits and potentially contributes to the pathogenesis of anxiety disorders by shaping fear-related limbic activity...
  40. ncbi Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response
    Katharina Domschke
    Department of Psychiatry, University of Muenster, Germany
    Int J Neuropsychopharmacol 13:93-101. 2010
    ..Post-hoc analyses provide some preliminary support for a potential minor role of genetic variation in BDNF and antidepressant treatment outcome in the context of melancholic depression...
  41. pmc Affect-modulated startle: interactive influence of catechol-O-methyltransferase Val158Met genotype and childhood trauma
    Benedikt Klauke
    Department of Psychiatry and Psychotherapy, University of Muenster, Muenster, Germany
    PLoS ONE 7:e39709. 2012
    ....
  42. doi Serotonin transporter gene and childhood trauma--a G × E effect on anxiety sensitivity
    Benedikt Klauke
    Department of Psychiatry and Psychotherapy, University of Muenster, Muenster, Germany
    Depress Anxiety 28:1048-57. 2011
    ..Thus, a gene-environment interaction (G × E) study was conducted with respect to anxiety sensitivity (AS) as a promising intermediate phenotype of anxiety disorders...
  43. ncbi Association of the functional -1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder
    Katharina Domschke
    Department of Psychiatry, University of Munster, Germany
    Int J Neuropsychopharmacol 9:349-55. 2006
    ..These serotonergic polymorphisms might increase the risk for panic disorder by contributing to an altered processing of emotional stimuli...
  44. ncbi Norepinephrine transporter (NET) promoter and 5'-UTR polymorphisms: association analysis in panic disorder
    Yoo J Lee
    Department of Psychiatry, University of Munster, Albert Schweitzer Str 11, D 48149 Munster, Germany
    Neurosci Lett 377:40-3. 2005
    ..05; T/C (rs2242446): p < 0.01). While our data do not support a major function of the NET gene in the development of panic disorder, it may play a role in the subgroup of panic disorder without agoraphobia...
  45. ncbi fMRI amygdala activation during a spontaneous panic attack in a patient with panic disorder
    Bettina Pfleiderer
    Department of Radiology, University of Muenster, Muenster, Germany
    World J Biol Psychiatry 8:269-72. 2007
    ....
  46. doi Life events in panic disorder-an update on "candidate stressors"
    Benedikt Klauke
    Department of Psychiatry and Psychotherapy, University of Muenster, Germany
    Depress Anxiety 27:716-30. 2010
    ....
  47. doi Adjunctive antidepressant treatment with quetiapine in agitated depression: positive effects on symptom reduction, psychopathology and remission rates
    Udo Dannlowski
    Department of Psychiatry, University of Munster, Germany
    Hum Psychopharmacol 23:587-93. 2008
    ..To investigate the adjunctive effects of quetiapine on overall treatment response and on specific symptoms in agitated depression...
  48. doi Risk variants in the S100B gene predict elevated S100B serum concentrations in healthy individuals
    Christa Hohoff
    Department of Psychiatry, University of Muenster, Muenster, Germany
    Am J Med Genet B Neuropsychiatr Genet 153:291-7. 2010
    ....
  49. doi Neuropeptide S receptor gene (NPSR) and life events: G × E effects on anxiety sensitivity and its subdimensions
    Benedikt Klauke
    Department of Psychiatry and Psychotherapy, University of Muenster, Germany
    World J Biol Psychiatry 15:17-25. 2014
    ....
  50. ncbi Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response
    Katharina Domschke
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Germany
    Int J Neuropsychopharmacol 17:1167-76. 2014
    ..This pharmaco-epigenetic approach could eventually aid in establishing epigenetic biomarkers of treatment response and thereby a more personalized treatment of MDD. ..
  51. pmc Clinical and molecular genetics of psychotic depression
    Katharina Domschke
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    Schizophr Bull 39:766-75. 2013
    ..Additionally, pharmacogenetic studies might aid in the development of a more personalized treatment of psychotic depression with an individually tailored antidepressive/antipsychotic pharmacotherapy according to genotype...
  52. ncbi Genetics of anxiety disorders - status quo and quo vadis
    Katharina Domschke
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, D 97080 Wurzburg, Germany
    Curr Pharm Des 18:5691-8. 2012
    ..Genetic research in anxiety disorders will be discussed with respect to its potential benefit for future efforts to develop innovative and individually tailored therapeutic approaches for patients with anxiety disorders...
  53. doi Insertion/deletion polymorphism in the gene for angiotensin converting enzyme (ACE) in panic disorder: A gender-specific effect?
    Borwin Bandelow
    Department of Psychiatry and Psychotherapy, University of Gottingen, Gottingen, Germany
    World J Biol Psychiatry 11:66-70. 2010
    ..0195), respectively, was observed. The present results provide further support for a potentially male-specific role of the less active ACE I allele in the pathogenesis of panic disorder, possibly by altering substance P levels...
  54. ncbi A case of non-SIADH-induced hyponatremia in depression after treatment with reboxetine
    Katja Koelkebeck
    University of Muenster, Department of Psychiatry, Muenster, Germany
    World J Biol Psychiatry 10:609-11. 2009
    ..Proposing further examination of the underlying pathomechanism of hyponatremia as a side effect of NaRIs, we discuss the importance of careful monitoring of serum sodium levels in patients treated with NaRIs...
  55. doi Associations between cognitive performance and cortisol reaction to the DEX/CRH test in patients recovered from depression
    Andreas Behnken
    Department of Psychiatry and Psychotherapy, University of Munster, 48149 Munster, Germany
    Psychoneuroendocrinology 38:447-54. 2013
    ..In the present study we were interested, whether these subtle impairments in cognitive functioning observed in patients recovered from depression compared to healthy control subjects are associated with HPA axis feedback sensitivity...
  56. doi Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder
    Thomas Dresler
    Department of Psychiatry and Psychotherapy, University of Tuebingen, Calwerstr 14, 72076, Tubingen, Germany
    J Neural Transm 120:3-29. 2013
    ....
  57. pmc Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD
    Heike Weber
    Department of Psychiatry, Psychosomatics and Psychotherapy, Psychiatric Neurobiology and Bipolar Disorder Program, University of Wurzburg, Wurzburg, Germany
    Neuropsychopharmacology 36:2076-85. 2011
    ..We demonstrate an association of DGKH with BPD, UPD, and aADHD by applying a two-stage design. These disorders share the feature of mood instability, so that this phenotype might be associated with genetic variation in DGKH...
  58. ncbi The impact of depression on musical ability
    Paul Reker
    Department of Neurology, University of Munster, Albert Schweitzer Campus 1, 48149 Munster, Germany
    J Affect Disord 156:150-5. 2014
    ....
  59. ncbi Patho-genetics of posttraumatic stress disorder
    Katharina Domschke
    Department of Psychiatry, University of Wurzburg, Wurzburg, Germany
    Psychiatr Danub 24:267-73. 2012
    ..g., imaging genetics) as well as pharmaco- and psychotherapy-genetic studies. Genetic research in PTSD will be discussed with respect to its potential benefit regarding innovative and individually tailored therapeutic approaches in PTSD...
  60. doi Behavioral genetics of affective and anxiety disorders
    Katharina Domschke
    Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, D 97080, Wurzburg, Germany
    Curr Top Behav Neurosci 12:463-502. 2012
    ..Finally, there is some evidence for genetic factors potentially shared between affective and anxiety disorders pointing to a possible overlapping phenotype between anxiety disorders and depression...
  61. ncbi Interaction of serotonergic and noradrenergic gene variants in panic disorder
    Christine M Freitag
    Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany
    Psychiatr Genet 16:59-65. 2006
    ....
  62. ncbi Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children
    Katharina Domschke
    Department of Genetics, Trinity College Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 134:110-4. 2005
    ..These findings suggest the importance of the 941G/T MAO-A polymorphism in the development of ADHD at least in the Irish population...
  63. ncbi The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Exp Brain Res 163:352-60. 2005
    ..Against this background, the slower clearance of dopamine associated with the methionine variant of the COMT gene polymorphism may be disadvantageous to cognition in ADHD...
  64. ncbi Agoraphobic behavior and panic attack: a study of male twins
    Ming Tsuang
    Harvard Institute of Psychiatric Epidemiology and Genetics, Harvard, USA
    J Anxiety Disord 18:799-807. 2004
    ..Agoraphobia following panic attack does not seem to reflect severity as agoraphobic behavior in the proband was unrelated to risk of panic attacks in the co-twin...