Daniel Dirkmann

Summary

Affiliation: University of Duisburg-Essen
Country: Germany

Publications

  1. doi Recombinant tissue-type plasminogen activator-evoked hyperfibrinolysis is enhanced by acidosis and inhibited by hypothermia but still can be blocked by tranexamic acid
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Germany
    J Trauma Acute Care Surg 74:482-8. 2013
  2. doi Factor XIII and tranexamic acid but not recombinant factor VIIa attenuate tissue plasminogen activator-induced hyperfibrinolysis in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Anesth Analg 114:1182-8. 2012
  3. doi Hypothermia and acidosis synergistically impair coagulation in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 106:1627-32. 2008
  4. doi First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 115:1179-91. 2011
  5. doi Potential value of transfusion protocols in cardiac surgery
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Germany
    Curr Opin Anaesthesiol 26:230-43. 2013
  6. doi Coagulation management in patients undergoing mechanical circulatory support
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinkum Essen, Universitat Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Best Pract Res Clin Anaesthesiol 26:179-98. 2012
  7. doi The GNB3 C825T polymorphism influences platelet aggregation in human whole blood
    Fabian Dusse
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital, University of Duisburg Essen, Essen, Germany
    Pharmacogenet Genomics 22:43-9. 2012
  8. doi [Platelet function analysis with point-of-care methods]
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen
    Herz 33:297-305. 2008

Detail Information

Publications8

  1. doi Recombinant tissue-type plasminogen activator-evoked hyperfibrinolysis is enhanced by acidosis and inhibited by hypothermia but still can be blocked by tranexamic acid
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Germany
    J Trauma Acute Care Surg 74:482-8. 2013
    ....
  2. doi Factor XIII and tranexamic acid but not recombinant factor VIIa attenuate tissue plasminogen activator-induced hyperfibrinolysis in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany
    Anesth Analg 114:1182-8. 2012
    ....
  3. doi Hypothermia and acidosis synergistically impair coagulation in human whole blood
    Daniel Dirkmann
    Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Essen, Germany
    Anesth Analg 106:1627-32. 2008
    ..Hypothermia and acidosis were reported to influence coagulopathy in different clinical settings. We evaluated whole blood coagulation to determine the effects of hypothermia and/or acidosis on hemostasis...
  4. doi First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen, Germany
    Anesthesiology 115:1179-91. 2011
    ..We developed and implemented an algorithm for coagulation management in cardiovascular surgery based on first-line administration of coagulation factor concentrates combined with point-of-care thromboelastometry/impedance aggregometry...
  5. doi Potential value of transfusion protocols in cardiac surgery
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Universitat Duisburg Essen, Essen, Germany
    Curr Opin Anaesthesiol 26:230-43. 2013
    ..The 16 studies fitting these search criteria have evaluated the impact of the implementation of ROTEM/TEG based coagulation management algorithms on transfusion requirement and outcome in overall 8507 cardiovascular surgical patients...
  6. doi Coagulation management in patients undergoing mechanical circulatory support
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinkum Essen, Universitat Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Best Pract Res Clin Anaesthesiol 26:179-98. 2012
    ..However, coagulation management in patients undergoing mechanical circulatory support therapy is somehow like navigating between Scylla and Charybdis, and development of protocols based on POC testing seems to be beneficial...
  7. doi The GNB3 C825T polymorphism influences platelet aggregation in human whole blood
    Fabian Dusse
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital, University of Duisburg Essen, Essen, Germany
    Pharmacogenet Genomics 22:43-9. 2012
    ..We tested the hypothesis that the C825T polymorphism of the gene GNB3 encoding the G-protein β-3 subunit and the platelet GPIIIa Pl(A1)/(A2) polymorphism of the glycoprotein IIIa influence platelet aggregation...
  8. doi [Platelet function analysis with point-of-care methods]
    Klaus Görlinger
    Klinik für Anästhesiologie und Intensivmedizin, Universitatsklinikum Essen, Essen
    Herz 33:297-305. 2008
    ..On the other hand, this medication can result in an increased risk of perioperative bleeding. In both situations control of the efficiency of therapy or rather the assessment of the impairment of hemostasis is of vital importance...