M Dietlein

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. pmc The implications of 18F-FDG PET for the diagnosis of endoprosthetic loosening and infection in hip and knee arthroplasty: results from a prospective, blinded study
    K St Delank
    Department of Orthopaedic Surgery Cologne University, Joseph Stelzmann Strasse 9, 50931 Koeln, Germany
    BMC Musculoskelet Disord 7:20. 2006
  2. ncbi request reprint [Reimbursement of the PET in oncology in Europe: a questionnaire based survey]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, 50924 Cologne
    Nuklearmedizin 42:80-5. 2003
  3. ncbi request reprint Management of multinodular goiter in Germany (Papillon 2005): do the approaches of thyroid specialists and primary care practitioners differ?
    M Dietlein
    Department of Nuclear Medicine, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Nuklearmedizin 46:65-75. 2007
  4. ncbi request reprint Development of anti-CD30 radioimmunoconstructs (RICs) for treatment of Hodgkin's lymphoma. Studies with cell lines and animal studies
    Markus Dietlein
    Department for Nuclear Medicine, University of Cologne, 50937 Cologne, Germany
    Nuklearmedizin 49:97-105. 2010
  5. ncbi request reprint [Therapy for non-toxic multinodular goiter: radioiodine therapy as attractive alternative to surgery]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 45:21-34; quiz N1-2. 2006
  6. ncbi request reprint [The incidentaloma of the thyroid. Over- or underuse of diagnostic procedure for an epidemiologic finding?]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln
    Nuklearmedizin 44:213-24; quiz N41-2. 2005
  7. ncbi request reprint [18F-Fluorodeoxyglucose positron emission tomography in restaging of colorectal cancer]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln, Germany
    Nuklearmedizin 42:145-56. 2003
  8. ncbi request reprint [Prevention, screening and therapy of thyroid diseases and their cost-effectiveness]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln, Germany
    Nuklearmedizin 42:181-9. 2003
  9. ncbi request reprint [Overtherapy or undertherapy for papillary thyroid microcarcinoma? Therapeutic considerations for radioiodine ablation]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universität zu Köln 50924 Köln
    Nuklearmedizin 43:107-14. 2004
  10. ncbi request reprint [Guideline for radioiodine therapy for benign thyroid diseases (version 3)]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Kerpener Strasse 62, 50924 Köln, Germany
    Nuklearmedizin 43:217-20. 2004

Collaborators

Detail Information

Publications89

  1. pmc The implications of 18F-FDG PET for the diagnosis of endoprosthetic loosening and infection in hip and knee arthroplasty: results from a prospective, blinded study
    K St Delank
    Department of Orthopaedic Surgery Cologne University, Joseph Stelzmann Strasse 9, 50931 Koeln, Germany
    BMC Musculoskelet Disord 7:20. 2006
    ..The aim of the current study was to evaluate the clinical value of 18F-Fluoro-deoxyglucose positron emission tomography (18F-FDG PET) as a diagnostic modality for inflammation and loosening in hip and knee joint prostheses...
  2. ncbi request reprint [Reimbursement of the PET in oncology in Europe: a questionnaire based survey]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, 50924 Cologne
    Nuklearmedizin 42:80-5. 2003
    ..The discussion in Germany about the reimbursement of the (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in oncology should make use of the experience from the other European countries...
  3. ncbi request reprint Management of multinodular goiter in Germany (Papillon 2005): do the approaches of thyroid specialists and primary care practitioners differ?
    M Dietlein
    Department of Nuclear Medicine, University of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Nuklearmedizin 46:65-75. 2007
    ..Large-scale survey to focus on management of multinodular goiter and to compare the approaches of practitioners in primary care and thyroid specialists in Germany...
  4. ncbi request reprint Development of anti-CD30 radioimmunoconstructs (RICs) for treatment of Hodgkin's lymphoma. Studies with cell lines and animal studies
    Markus Dietlein
    Department for Nuclear Medicine, University of Cologne, 50937 Cologne, Germany
    Nuklearmedizin 49:97-105. 2010
    ..Comparison of the binding affinity to a CD30-positive Hodgkin lymphoma (HL) cell line and biodistribution in HL bearing mice of new anti-CD30 radioimmunoconjugates (RICs) of varying structure and labelling nuclides...
  5. ncbi request reprint [Therapy for non-toxic multinodular goiter: radioiodine therapy as attractive alternative to surgery]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 45:21-34; quiz N1-2. 2006
    ..A phase I study for dose finding is running in the USA...
  6. ncbi request reprint [The incidentaloma of the thyroid. Over- or underuse of diagnostic procedure for an epidemiologic finding?]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln
    Nuklearmedizin 44:213-24; quiz N41-2. 2005
    ....
  7. ncbi request reprint [18F-Fluorodeoxyglucose positron emission tomography in restaging of colorectal cancer]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln, Germany
    Nuklearmedizin 42:145-56. 2003
    ....
  8. ncbi request reprint [Prevention, screening and therapy of thyroid diseases and their cost-effectiveness]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln, Germany
    Nuklearmedizin 42:181-9. 2003
    ..The ablative radioiodine dose-regime is cost-effective as a first line therapy if the risk of relapse after ATD exceeds 60%...
  9. ncbi request reprint [Overtherapy or undertherapy for papillary thyroid microcarcinoma? Therapeutic considerations for radioiodine ablation]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universität zu Köln 50924 Köln
    Nuklearmedizin 43:107-14. 2004
    ....
  10. ncbi request reprint [Guideline for radioiodine therapy for benign thyroid diseases (version 3)]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Kerpener Strasse 62, 50924 Köln, Germany
    Nuklearmedizin 43:217-20. 2004
    ..The pragmatic recommendations for the combined use of radioiodine and glucocorticoids remained unchanged in the 3rd version...
  11. ncbi request reprint Incidental multifocal papillary microcarcinomas of the thyroid: is subtotal thyroidectomy combined with radioiodine ablation enough?
    Markus Dietlein
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Nucl Med Commun 26:3-8. 2005
    ..The extent of thyroid resection and the necessity of lymph node dissection has become an issue of controversy in patients with incidental multifocal papillary microcarcinoma...
  12. ncbi request reprint Amiodarone-induced thyrotoxicosis due to destructive thyroiditis: therapeutic recommendations
    M Dietlein
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Exp Clin Endocrinol Diabetes 113:145-51. 2005
    ..Our hypothesis was that the common practice of thyroid testing before prescription of amiodarone would reduce the incidence of pure type 1 AIT, though a stringent classification may be difficult (mixed type AIT)...
  13. ncbi request reprint Administration of additional inactive iodide during radioiodine therapy for Graves' disease: who might benefit?
    M Dietlein
    Department of Nuclear Medicine, University of Cologne, 50924 Cologne, Germany
    Nuklearmedizin 46:77-84. 2007
    ..The consequence is rapid 131I turnover and impending failure of radioiodine therapy. Can administration of additional inactive iodide improve 131I kinetics?..
  14. doi request reprint Recombinant human TSH versus hypothyroidism. Cost-minimization-analysis in the follow-up care of differentiated thyroid carcinoma
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin des Universitätsklinikums Köln, Kerpener Str 62, 50937 Koln, Germany
    Nuklearmedizin 49:216-24. 2010
    ..The second aim was to determine patients' preference for one procedure or the other...
  15. ncbi request reprint [Procedure guideline for radioiodine test (Version 3)]
    M Dietlein
    Kliniken und Polikliniken für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 46:198-202. 2007
    ..The patient has to avoid iodine-containing medication and the possibility of additives of iodine in vitamin- and electrolyte-supplementation has to be considered...
  16. ncbi request reprint [Procedure guideline for thyroid scintigraphy (version 3)]
    M Dietlein
    Kliniken und Polikliniken für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 46:203-5. 2007
    ..For this, an imaging time of 10 minutes is generally needed using a high resolution collimator for thyroid imaging...
  17. ncbi request reprint [Procedure guideline for iodine-131 whole-body scintigraphy for differentiated thyroid cancer (version 3)]
    M Dietlein
    Kliniken und Polikliniken für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 46:206-12. 2007
    ..Increased anti-thyroglobulin-antibodies or incomplete recovery-testing make an individual strategy of follow-up care necessary, which include (131)I WBS...
  18. ncbi request reprint [Routine measurement of serum calcitonin in patients with nodular thyroid disorders?]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, Koln, Germany
    Nuklearmedizin 47:65-72. 2008
    ..All this and the choice of a skilled surgeon, experienced in thyroidectomy and lymphadenectomy with a low rate of local complications are the rationale to recommend calcitonin-screening primarily in centers for thyroid disorders...
  19. ncbi request reprint [Procedure guidelines for radioiodine therapy of differentiated thyroid cancer (version 3)]
    M Dietlein
    Kliniken und Polikliniken für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 46:213-9. 2007
    ..Regarding the best possible protection of salivary glands the evidence is insufficient to recommend a specific setting. To minimize the risk of dental caries due to xerostomia patients should use preventive strategies for dental hygiene...
  20. ncbi request reprint [Obesity, energy regulation and thyroid function: is borderline elevated TSH-level the cause or secondary phenomenon of obesity]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, Koln
    Nuklearmedizin 47:181-7. 2008
    ..As body weight gain is observed in all TSH groups, a special concept for prevention and therapy of obesity (diet, daily exercise, behaviour training) should be initiated early and additionally to medication...
  21. ncbi request reprint [Guideline for radioiodine therapy for benign thyroid diseases (version 4)]
    M Dietlein
    Kliniken und Polikliniken für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 46:220-3. 2007
    ..After counseling, the patient gives informed consent to the preferred therapy. The period after radioiodine therapy of benign disorders until conception of at least four months was adapted to the European recommendation...
  22. ncbi request reprint Survey of management of solitary thyroid nodules in Germany
    M Dietlein
    Department of Nuclear Medicine, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Nuklearmedizin 47:87-96. 2008
    ..To compare the opinions of practitioners in primary care with those of thyroid specialists in Germany on the management of solitary thyroid nodules (Papillon 2005)...
  23. ncbi request reprint Thoracic positron emission tomography using 18F-fluorodeoxyglucose for the evaluation of residual mediastinal Hodgkin disease
    M R Weihrauch
    Department of Internal Medicine I, University of Cologne, Germany
    Blood 98:2930-4. 2001
    ..On the other hand, a positive PET result indicates a significantly higher risk of relapse and demands further diagnostic procedures and a closer follow-up...
  24. ncbi request reprint Graves' disease and radioiodine therapy. Is success of ablation dependent on the choice of thyreostatic medication?
    C Kobe
    Department of Nuclear Medicine, University of Cologne, Kerpener Strasse 62, Cologne, Germany
    Nuklearmedizin 47:153-6. 2008
    ..This study was performed to analyse the impact of the choice of antithyroid drugs (ATD) on the outcome of ablative radioiodine therapy (RIT) in patients with Graves' disease...
  25. ncbi request reprint [Procedure guidelines for radioiodine therapy of differentiated thyroid cancer (version 2)]
    M Dietlein
    Klinik und Poliklinik fur Nuklearmedizin, Universität zu Köln 50924 Köln
    Nuklearmedizin 43:115-20. 2004
    ....
  26. ncbi request reprint [Procedure guideline for iodine-131 whole-body scintigraphy for differentiated thyroid cancer (version 2)]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Köln
    Nuklearmedizin 42:123-5. 2003
    ..Before planning the iodine-131 scintigraphy the patient has to avoid iodine-containing medication and the possibility of additives of iodine in vitamin- and electrolyte-supplementation has to be considered...
  27. ncbi request reprint Graves' disease and radioiodine therapy. Is success of ablation dependent on the achieved dose above 200 Gy?
    C Kobe
    Department of Nuclear Medicine, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Nuklearmedizin 47:13-7. 2008
    ..This study was performed to determine the results of ablative radioiodine therapy (RIT) when the achieved dose in the thyroid was above 200 Gy and to characterize predictive factors for treatment outcome...
  28. doi request reprint Calcitonin screening in patients with thyroid nodules. Diagnostic value
    C Schneider
    Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str 62, 50937 Cologne, Germany
    Nuklearmedizin 51:228-33. 2012
    ..The positive predictive value (PPV) of a slightly elevated basal calcitonin (CT) for the diagnosis of medullary thyroid cancer (MTC) is still under debate...
  29. ncbi request reprint Radioiodine therapy and thyrostatic drugs and iodine
    D Moka
    Department of Nuclear Medicine, University of Cologne, Joseph Stelzmannstrasse 9, 50924 Köln, Germany
    Eur J Nucl Med Mol Imaging 29:S486-91. 2002
    ..Thus, improving the biokinetics of radioiodine will allow lower activities to be administered with lower effective doses to the rest of the body, while achieving an equally effective target dose in the thyroid...
  30. doi request reprint No protection of the ovarian follicle pool with the use of GnRH-analogues or oral contraceptives in young women treated with escalated BEACOPP for advanced-stage Hodgkin lymphoma. Final results of a phase II trial from the German Hodgkin Study Group
    K Behringer
    German Hodgkin Study Group, First Department of Internal Medicine, University Hospital Cologne, Kerpener Strasse 62, Cologne, Germany
    Ann Oncol 21:2052-60. 2010
    ..Therefore, the GHSG investigated the use of gonadotropin-releasing hormone-analogues (GnRH-a) and oral contraceptives (OC) in young women with advanced-stage Hodgkin lymphoma (HL)...
  31. ncbi request reprint [Radioimmunotherapy with yttrium-90 ibritumomab tiuxetan. Clinical considerations, radiopharmacy, radiation protection, perspectives]
    K Schomacker
    Klinik und Poliklinik fur Nuklearmedizin, der Universität zu Köln, Kerpener Str 62, 50924 Köln
    Nuklearmedizin 44:166-77. 2005
    ..However, this procedure is not part of the approval...
  32. ncbi request reprint Disease-free survival in papillary and follicular thyroid carcinoma. Comparison between UICC 5th and 7th classifications of T stage, and the prognostic value of primary tumour size
    M Meixner
    Department of Nuclear Medicine, University Hospital of Cologne, Germany
    Nuklearmedizin 52:71-80. 2013
    ..T stage was redefined for patients with differentiated thyroid carcinoma (DTC) between the 5th and 7th versions of the UICC tumour classification system...
  33. ncbi request reprint [Procedure guideline for radioiodine test (version 2)]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Cologne
    Nuklearmedizin 42:116-9. 2003
    ..The patient has to avoid iodine-containing medication and the possibility of additives of iodide in vitamin- or electrolyte-supplementation has to be considered...
  34. ncbi request reprint [Procedure guideline for thyroid scintigraphy (version 2)]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, 50924 Cologne
    Nuklearmedizin 42:120-2. 2003
    ..The interpretation of the technetium-99m uptake requires the knowledge of TSH concentration...
  35. ncbi request reprint MIBI scintigraphy in hypofunctioning thyroid nodules--can it predict the dignity of the lesion?
    P Theissen
    Department of Nuclear Medicine, University of Cologne, Germany
    Nuklearmedizin 48:144-52. 2009
    ..The present study investigates whether the above claim is also valid in Germany, a country with a long-standing and persistent, mild iodine deficiency and a high incidence of nodules in large goiters with a low prevalence of malignancy...
  36. ncbi request reprint 18F-FDG PET for detecting recurrent head and neck cancer, local lymph node involvement and distant metastases. Comparison of qualitative visual and semiquantitative analysis
    M Schmidt
    Klinik und Poliklinik fur Nuklearmedizin, Klinikum der Universität zu Köln, Joseph Stelzmann Str 9, 50924 Köln, Germany
    Nuklearmedizin 43:91-101;quiz 102-4. 2004
    ..Assessment of the clinical value of (18)F-FDG-PET for detection of recurrent head and neck cancer, local lymph node involvement and distant metastases comparing a qualitative visual with a semiquantitative analysis (SUV values)...
  37. ncbi request reprint [Hodgkin's lymphoma in nuclear medicine: diagnostic and therapeutic aspects]
    J O Staak
    Klinik I fur Innere Medizin, Labor für Immuntherapie, Universitat zu Koln, 50924 Köln
    Nuklearmedizin 42:19-24. 2003
    ..Thus, a new radioimmunoconstruct consisting of the murine anti-CD30 antibody Ki-4 labeled with iodine-131 was developed for patients with relapsed or refractory HL...
  38. ncbi request reprint [FDG-PET in Hodgkin lymphoma]
    C Kobe
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Kerpener Str 62, 50937 Koln, Germany
    Nuklearmedizin 47:235-8; quiz N75-6. 2008
    ..The criteria used for the PET interpretation have been standardized by the German study groups for Hodgkin lymphoma patients and will be reevaluated in the current studies...
  39. ncbi request reprint Radioiodine therapy of Graves' hyperthyroidism in patients without pre-existing ophthalmopathy: can glucocorticoids prevent the development of new ophthalmopathy?
    B Dederichs
    Department of Nuclear Medicine, University of Cologne, Germany
    Exp Clin Endocrinol Diabetes 114:366-70. 2006
    ..Radioiodine therapy (RIT) combined with glucocorticoids is an effective therapy for Graves' disease, but it is debatable whether glucocorticoids should be applied in patients without Graves' ophthalmopathy (GO)...
  40. ncbi request reprint Risk stratification of patients with locally aggressive differentiated thyroid cancer. Results of the MSDS trial
    Burkhard Riemann
    Department of Nuclear Medicine, University Hospital, 48149 Muenster, Germany
    Nuklearmedizin 49:79-84. 2010
    ..The aim of the present study was to compare the survival of patients with minimum and extensive extrathyroidal growth according to the new AJCC/UICC TNM staging system 2009...
  41. ncbi request reprint [Established nuclear medicine techniques for tumour diagnosis (tumour SPECT): can they still compete with (18)F-FDG-PET?]
    M Schmidt
    Klinik und Poliklinik fur Nuklearmedizin, Klinikum der Universität zu Köln, Kerpener Str 62, 50937 Koln
    Nuklearmedizin 44:37-48; quiz N2-3. 2005
    ..Future developments concerning new SPECT radiopharmaceuticals and image fusion such as SPECT/CT are expected...
  42. ncbi request reprint Iterative reconstruction: an improvement of technetium-99m MIBI SPET for the detection of parathyroid adenomas?
    D Moka
    Department of Nuclear Medicine, University of Cologne, Germany
    Eur J Nucl Med 27:485-9. 2000
    ..There is a further improvement in sensitivity and image quality when iterative reconstruction is used instead of FBP...
  43. doi request reprint Recombinant human TSH increases uptake and effective half-life of radioiodine in thyroid hormone secreting metastases of follicular thyroid cancer
    C Schneider
    University Hospital of Cologne, Department of Nuclear Medicine, Cologne, Germany
    Exp Clin Endocrinol Diabetes 120:160-3. 2012
    ..These effects of rhTSH should be considered when fixed activities of ¹³¹I are prescribed...
  44. ncbi request reprint [Interactions between brain, psyche and thyroid]
    M Schmidt
    Klinik und Poliklinik fur Nuklearmedizin, Universitätsklinikum Köln, Kerpener Str 62, 50937 Koln
    Nuklearmedizin 47:225-34. 2008
    ..Psychiatric symptoms associated with hypothyroidism are usually reversible under levothyroxine within 4-8 weeks. The standard for hypothyroidism is mono-levothyroxine therapy...
  45. ncbi request reprint Guidelines on radioiodine therapy for differentiated thyroid carcinoma: impact on clinical practice
    M Biermann
    Department of Nuclear Medicine, Munster University, Albert Schweitzer Str 30 33, 48129 Munster, Germany
    Nuklearmedizin 44:229-34, 236-7. 2005
    ..For the examination of the impact on clinical practice of the guidelines for differentiated thyroid carcinoma (DTC), treatment data from the ongoing Multicenter Study Differentiated Thyroid Carcinoma (MSDS) were analyzed...
  46. doi request reprint The use of thyrogen in the treatment of differentiated thyroid carcinoma: an intraindividual comparison of clinical effects and implications of daily life
    C Dueren
    Department of Nuclear Medicine, University of Wuerzburg, Wuerzburg, Germany
    Exp Clin Endocrinol Diabetes 118:513-9. 2010
    ..Second aim was to determine a clear patient preference for the one method or the other...
  47. doi request reprint Guidelines for radioiodine therapy of differentiated thyroid cancer
    M Luster
    Department of Nuclear Medicine, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Eur J Nucl Med Mol Imaging 35:1941-59. 2008
    ....
  48. ncbi request reprint Is there a benefit of 131 I-MIBG therapy in the treatment of children with stage 4 neuroblastoma? A retrospective evaluation of The German Neuroblastoma Trial NB97 and implications for The German Neuroblastoma Trial NB2004
    M Schmidt
    Department of Nuclear Medicine, University of Cologne, Kerpener Strasse 62, 50937 Koln, Germany
    Nuklearmedizin 45:145-51; quiz N39-40. 2006
    ..131)I-meta-iodobenzylguanidine ((131)I-MIBG) therapy has been used in neuroblastoma treatment for many years but its value in high intensive first line treatment protocols is not exactly known...
  49. ncbi request reprint Fluorine-18 fluorodeoxyglucose positron emission tomography in medullary thyroid cancer: results of a multicentre study
    M Diehl
    Department of Nuclear Medicine, University of Frankfurt Main, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Eur J Nucl Med 28:1671-6. 2001
    ..It is concluded that FDG-PET is a useful method in the staging and follow-up of MTC...
  50. ncbi request reprint Localization of 131I-labelled monoclonal antibody ERIC1 in a subcutaneous xenograft model of neuroblastoma in SCID mice
    Christina Otto
    Department of Nuclear Medicine, University of Cologne, Germany
    Nucl Med Commun 27:171-8. 2006
    ..To evaluate a novel strategy of immunolocalization of human neuroblastoma by targeting the neural cell adhesion molecule (NCAM), which is over-expressed on neuroblastoma...
  51. ncbi request reprint [18F]-Fluorodeoxyglucose-positron emission tomography for the assessment of histopathologic response and prognosis after completion of neoadjuvant chemoradiation in esophageal cancer
    Daniel Vallbohmer
    General, Visceral, and Cancer Surgery, University of Cologne, Germany
    Ann Surg 250:888-94. 2009
    ....
  52. ncbi request reprint 99mTc-MIBI SPECT in primary hyperparathyroidism. Influence of concomitant vitamin D deficiency for visualization of parathyroid adenomas
    M Schmidt
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Nuklearmedizin 47:1-7. 2008
    ..AIM of the study was to analyse the influence of a concomitant vitamin D deficiency on the results of (99m)Tc-MIBI studies in patients (pts) with primary hyperparathyroidism (pHPT)...
  53. ncbi request reprint Diagnostic value and therapeutic impact of (18)F-FDG-PET/CT in differentiated thyroid cancer. Results of a German multicentre study
    B Riemann
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Campus 1, 48149 Munster, Germany
    Nuklearmedizin 52:1-6. 2013
    ..In addition, it was the aim to investigate the impact of (18)F-FDG-PET/CT on the therapeutic management...
  54. doi request reprint 123I-FP-CIT SPECT imaging of the dopaminergic state. Visual assessment of dopaminergic degeneration patterns reflects quantitative 2D operator-dependent and 3D operator-independent techniques
    D Kahraman
    Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Nuklearmedizin 51:244-51. 2012
    ..The aim of our study was to investigate if visual assessment according to a predefined image grading scale reflects the results of quantitative assessment techniques...
  55. ncbi request reprint Long-term follow-up of 82 patients with chronic disease of the thoracic aorta using spin-echo and cine gradient magnetic resonance imaging
    M Schmidta
    Klinik und Poliklinik fur Nuklearmedizin, Germany
    Magn Reson Imaging 18:795-806. 2000
    ..The results of magnetic resonance imaging provided the rationale for either (re-)operation or conservative management, thus guiding patient management...
  56. ncbi request reprint [18F]-fluorodeoxyglucose-positron emission tomography for the assessment of histopathologic response and prognosis after completion of neoadjuvant chemotherapy in gastric cancer
    D Vallbohmer
    Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany
    J Surg Oncol 102:135-40. 2010
    ..We evaluated the potential of FDG-PET for the assessment of response and prognosis in the multimodality treatment of gastric cancer...
  57. ncbi request reprint Non-Q-wave myocardial infarction: impaired myocardial energy metabolism in regions with reduced 99mTc-MIBI accumulation
    D Moka
    Department of Nuclear Medicine, University of Cologne, , Germany
    Eur J Nucl Med 28:602-7. 2001
    ..Our results indicate that morphological remodelling after NQWI is accompanied by fundamental changes in cardiac energy metabolism...
  58. ncbi request reprint [Graves' disease nd toxic nodular goiter--radioiodine therapy]
    H Schicha
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Deutschland
    Nuklearmedizin 41:63-70. 2002
    ..Comparing benefits, adverse effects, costs, and conveniences of both treatment strategies the authors conclude that radioiodine therapy should be preferred as first line therapy in 60-70% of the patients with Graves' hyperthyroidism...
  59. pmc Positron emission tomography has a high negative predictive value for progression or early relapse for patients with residual disease after first-line chemotherapy in advanced-stage Hodgkin lymphoma
    Carsten Kobe
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Blood 112:3989-94. 2008
    ..Until then, response adapted therapy guided by PET for HL patients seems to be a promising approach that should be further evaluated in clinical trials. This trial is registered at http://isrctn.org study as #ISRCTN32443041...
  60. doi request reprint Primary tumour size is a prognostic parameter in patients suffering from differentiated thyroid carcinoma with extrathyroidal growth: results of the MSDS trial
    Jan Alexander Krämer
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Strasse 33, Munster, Germany
    Eur J Endocrinol 163:637-44. 2010
    ....
  61. ncbi request reprint Whole-body positron emission tomography using 18F-fluorodeoxyglucose for initial staging of patients with Hodgkin's disease
    M R Weihrauch
    Department of Internal Medicine I, University of Cologne, Immunologisches Labor Haus 16, Joseph Stelzmann Str 9, 50924 Cologne, Germany
    Ann Hematol 81:20-5. 2002
    ..However, PET should not be used as the only imaging modality as it failed to detect CT-positive, active tumor regions in some cases...
  62. ncbi request reprint [Positron emission tomography 2008 in Germany - results of the query and current status]
    J Kotzerke
    Klinik und Poliklinik fur Nuklearmedizin, Universitatsklinikum Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Nuklearmedizin 49:58-64. 2010
    ..The working group on positron emission tomography (PET) of the DGN (German Society of Nuclear Medicine) initiated this first survey to collect and analyse information on the practise of PET in Germany in the year 2008...
  63. ncbi request reprint [Nuclear medical inpatient treatment in Germany - analysis of structured quality reports 2004-2008]
    R Lorenz
    Klinik und Poliklinik fur Nuklearmedizin, Universitat Wurzburg, Universitätsklinikum Haus A4, Oberdürrbacher Str 6, 97080 Wurzburg, Germany
    Nuklearmedizin 49:49-57. 2010
    ....
  64. ncbi request reprint [The lymph node staging of malignant testicular germ-cell tumors]
    B Krug
    Institut und Poliklinik für Radiologische Diagnostik, Universitat zu Koln
    Rofo 171:87-94. 1999
    ..The present review presents and discusses the current value of the available imaging procedures for staging and follow-up of malignant testicular germ cell tumors in relation to modern therapy regimens...
  65. ncbi request reprint [Cost-effectiveness of PET in the management algorithms of lung tumors: comparison of health economic data]
    M Dietlein
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, Deutschland
    Nuklearmedizin 40:122-8. 2001
    ..Economic data from the USA and Japan also demonstrated the cost-effectiveness of PET-based algorithms for the management of lung tumours...
  66. doi request reprint Radioiodine therapy of benign thyroid disorders: what are the effective thyroidal half-life and uptake of 131I?
    Carsten Kobe
    Department of Nuclear Medicine, University of Cologne, Cologne D 50924, Germany
    Nucl Med Commun 31:201-5. 2010
    ..We analyzed the radioiodine half-life and uptake in a large number of patients for use in a semi-individual calculation...
  67. doi request reprint [Should all patients with thyroid nodules > or = 1 cm undergo fine-needle aspiration biopsy?]
    Harald Schicha
    Klinik und Poliklinik für Nuklearmedizin der Universität zu Köln, Kerpener Str 62, 50937 Koln
    Nuklearmedizin 48:79-83. 2009
    ..A combination of sonographic criteria and scintigraphy, even in patients with normal TSH-levels, is suited to selected thyroid nodules for FNAB...
  68. doi request reprint Mean and maximum standardized uptake values in [18F]FDG-PET for assessment of histopathological response in oesophageal squamous cell carcinoma or adenocarcinoma after radiochemotherapy
    Matthias Schmidt
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Eur J Nucl Med Mol Imaging 36:735-44. 2009
    ..To evaluate the potential of [(18)F]fluorodeoxyglucose positron emission tomography (FDG-PET) for the assessment of histopathological response and survival after neoadjuvant radiochemotherapy in patients with oesophageal cancer...
  69. ncbi request reprint Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas
    Matthias Schmidt
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Joseph Stelzmann Strasse 9, 50924 Köln, Germany
    Eur J Nucl Med Mol Imaging 29:1571-80. 2002
    ..It is concluded that somatostatin receptor scintigraphy provides important information in patients with suspected paragangliomas of the head and neck region and has a strong impact on further therapeutic management...
  70. ncbi request reprint Prognostic significance of 18F-fluorodeoxyglucose positron emission tomography in lymphoma
    Martin R Weihrauch
    Department of Internal Medicine I, University of Cologne, Cologne, Germany
    Leuk Lymphoma 44:15-22. 2003
    ..To assess the prognostic implications of PET in the post-therapeutic setting, we performed a MedLine Search and reviewed the current available studies on this important issue together with our own data...
  71. ncbi request reprint Stability of radioactive colloids for radiation synovectomy: influence of X-ray contrast agents, anaesthetics and glucocorticoids in vitro
    Klaus Schomacker
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Nucl Med Commun 26:1027-35. 2005
    ....
  72. ncbi request reprint Cell death induced by 131 I in a differentiated thyroid carcinoma cell line in vitro: necrosis or apoptosis?
    Kathrin Marx
    Department of Nuclear Medicine, University of Cologne, Germany
    Nucl Med Commun 27:353-8. 2006
    ..The apoptotic and necrotic dose-response of thyroid carcinoma cells following irradiation with I was evaluated...
  73. ncbi request reprint Incidence of postradioiodine immunogenic hyperthyroidism/Graves' disease in relation to a temporary increase in thyrotropin receptor antibodies after radioiodine therapy for autonomous thyroid disease
    Matthias Schmidt
    Department of Nuclear Medicine, Informatics and Epidemiology, University of Cologne, Cologne, Germany
    Thyroid 16:281-8. 2006
    ....
  74. ncbi request reprint False-positive uptake of I-131 in a laryngocele mimicking thyroid remnant after thyroidectomy for papillary thyroid carcinoma
    Matthias Schmidt
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Clin Nucl Med 31:716-7. 2006
    ..The patient declined definitive operative revision of the laryngocele and is in good health 8 years after the diagnosis of papillary thyroid carcinoma...
  75. ncbi request reprint Is there a need for positron emission tomography imaging to stage the N0 neck in T1-T2 squamous cell carcinoma of the oral cavity or oropharynx?
    Ursula Schroeder
    Department of Otolaryngology Head and Neck Surgery, University of Cologne Medical Center, Cologne, Germany
    Ann Otol Rhinol Laryngol 117:854-63. 2008
    ....
  76. doi request reprint Yttrium-90 ibritumomab tiuxetan-induced complete remission in a patient with classical lymphocyte-rich Hodgkin's Lymphoma
    Roland Schnell
    Department I of Internal Medicine, University of Cologne, Germany
    Onkologie 31:49-51. 2008
    ..Thus, only very limited data of cHL patients treated with anti- CD20 immunoconstructs are available. To date, none of the patients treated with 90Y ibritumomab tiuxetan demonstrated any response...
  77. doi request reprint Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothyroxine
    Matthias Schmidt
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Thyroid 18:755-60. 2008
    ..The objective of the present study was to provide this information...
  78. ncbi request reprint [Assessment of endocrine disorders of the hypothalamic-pituitary axis by nuclear medicine techniques]
    M Schmidt
    Klinik und Poliklinik fur Nuklearmedizin, Universitat zu Koln, Deutschland
    Nuklearmedizin 41:80-90. 2002
    ..g. localization of small ACTH-producing pituitary adenomas, tumor localization in ectopic ACTH syndrome, localization of recurrent pituitary tissue, assessment of small incidentalomas, can not be definitely given yet...
  79. ncbi request reprint Thyroid hormone withdrawal in patients with differentiated thyroid carcinoma: a one hundred thirty-patient pilot survey on consequences of hypothyroidism and a pharmacoeconomic comparison to recombinant thyrotropin administration
    Markus Luster
    Department of Nuclear Medicine, University of Wurzburg, Germany
    Thyroid 15:1147-55. 2005
    ..In conclusion, hypothyroidism secondary to withdrawal causes important morbidity, safety risks, and productivity impairment. rhTSH avoids these drawbacks at roughly equivalent societal cost to that of withdrawal...
  80. ncbi request reprint Treatment of refractory Hodgkin's lymphoma patients with an iodine-131-labeled murine anti-CD30 monoclonal antibody
    Roland Schnell
    Department of Internal Medicine I, Department of Nuclear Medicine, University of Cologne, Germany
    J Clin Oncol 23:4669-78. 2005
    ..Thus, we developed a new radioimmunoconjugate consisting of the murine anti-CD30 monoclonal antibody (MAb) Ki-4 labeled with iodine-131 ((131)I)...
  81. doi request reprint Complete metabolic response in a patient with repeatedly relapsed non-small cell lung cancer harboring ROS1 gene rearrangement after treatment with crizotinib
    M Bos
    Department I of Internal Medicine, Center for Integrated Oncology Köln Bonn, University Hospital Cologne, Cologne, Germany
    Lung Cancer 81:142-3. 2013
    ..1). Our case exemplifies the need for rapid implementation of newly discovered rare genetic lung cancer subtypes in routine molecular diagnostics...
  82. ncbi request reprint Differentiation between healthy thyroid remnants and tumor tissue after radioiodine therapy in patients with differentiated thyroid carcinoma using in vitro phosphorus-31 magnetic resonance spectroscopy
    Detlef Moka
    Department of Nuclear Medicine, University of Cologne, Koln, Germany
    Am J Med 112:634-41. 2002
    ..We sought to determine whether plasma levels of several phospholipids could differentiate between healthy remnants of thyroid tissue and residual tumor tissue or metastases in patients with thyroid carcinoma...
  83. ncbi request reprint Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus
    Lucia Nogova
    Lung Cancer Group Cologne, Department I of Internal Medicine, Center for Integrated Oncology, University Hospital Cologne, Cologne, Germany
    J Nucl Med 50:1815-9. 2009
    ..Inhibition of glucose metabolism measured by (18)F-FDG PET was postulated to serve as a pharmacodynamic marker in everolimus-treated non-small cell lung cancer (NSCLC) patients...
  84. doi request reprint Radio-iodine therapy in differentiated thyroid cancer: indications and procedures
    Christoph Reiners
    Department of Nuclear Medicine, University of Wurzburg, Josef Schneider Strasse 2, 97080 Wurzburg, Germany
    Best Pract Res Clin Endocrinol Metab 22:989-1007. 2008
    ..The standard approach to preparation for 131I therapy in patients with metastases is endogenous hypothyroidism after thyroid hormone withdrawal...
  85. doi request reprint Radioiodine therapy for thyroid volume reduction of large goitres
    Juliane Bachmann
    Department of Nuclear Medicine, University Hospital of Cologne, Germany
    Nucl Med Commun 30:466-71. 2009
    ..To evaluate the effect of radioiodine therapy for volume reduction in large goitres...
  86. ncbi request reprint Imaging of central nervous system lymphomas with iodine-123 labeled rituximab
    Markus Dietlein
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Eur J Haematol 74:348-52. 2005
    ..If an uptake of therapeutic rituximab doses into PCNSL can be achieved remains questionable...
  87. doi request reprint PROLARA: prognosis-based lifetime attributable risk approximation for cancer from diagnostic radiation exposure
    Wolfgang Eschner
    Department of Nuclear Medicine, University of Cologne, 50924 Koeln, Germany
    Eur J Nucl Med Mol Imaging 37:131-5. 2010
    ..To evaluate the impact of the reduced life expectancy of patients (compared to a nonpatient group with the same age distribution) on their nominal risk of developing cancer from the diagnostic use of radiation...
  88. ncbi request reprint Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma
    Malik E Juweid
    Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
    J Clin Oncol 25:571-8. 2007
    ..To develop guidelines for performing and interpreting positron emission tomography (PET) imaging for treatment assessment in patients with lymphoma both in clinical practice and in clinical trials...
  89. ncbi request reprint Cost estimation of thyroid disorders in Germany
    George J Kahaly
    Department of Medicine I, Gutenberg University Hospital, Mainz, Germany
    Thyroid 12:909-14. 2002
    ..Sustainable elimination of iodine deficiency is technically possible, but it needs further commitment and support at all levels...