Philipp Diehl

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi [The role of microparticles in vascular diseases]
    P Diehl
    Abteilung für Innere Medizin III, Kardiologie und Angiologie, Medizinische Universitatsklinik, Hugstetter Strasse 55, Freiburg
    Hamostaseologie 28:203-6. 2008
  2. ncbi Enhanced microparticles in ventricular assist device patients predict platelet, leukocyte and endothelial cell activation
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    Interact Cardiovasc Thorac Surg 11:133-7. 2010
  3. ncbi Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    J Thromb Thrombolysis 31:173-9. 2011
  4. ncbi Discontinuation of long term clopidogrel therapy induces platelet rebound hyperaggregability between 2 and 6 weeks post cessation
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    Clin Res Cardiol 100:765-71. 2011
  5. ncbi Increased levels of circulating microparticles in patients with severe aortic valve stenosis
    Philipp Diehl
    Dept for Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, D 79106 Freiburg, Germany
    Thromb Haemost 99:711-9. 2008
  6. ncbi Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, 79106 Freiburg, Germany
    Basic Res Cardiol 105:379-87. 2010
  7. ncbi BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1
    Thomas Helbing
    Department for Cardiology, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    Arterioscler Thromb Vasc Biol 30:554-60. 2010
  8. ncbi Krüppel-like factor 15 regulates BMPER in endothelial cells
    Thomas Helbing
    Department of Cardiology, University of Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
    Cardiovasc Res 85:551-9. 2010
  9. ncbi [Is stent thrombosis the new Achilles heel of interventional cardiology? State of the Art clinical trials, causes and approaches for prevention]
    T Grumann
    Abteilung III für Kardiologie und Angiologie, Medizinische Universititäsklinik, Hugstetterstrasse 55, 79106 Freiburg
    Hamostaseologie 27:344-50. 2007

Collaborators

Detail Information

Publications9

  1. ncbi [The role of microparticles in vascular diseases]
    P Diehl
    Abteilung für Innere Medizin III, Kardiologie und Angiologie, Medizinische Universitatsklinik, Hugstetter Strasse 55, Freiburg
    Hamostaseologie 28:203-6. 2008
    ..They are detectable in many acute and chronic vascular diseases as a surrogate marker for disease activity but also play a role in the pathophysiology of vascular diseases...
  2. ncbi Enhanced microparticles in ventricular assist device patients predict platelet, leukocyte and endothelial cell activation
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    Interact Cardiovasc Thorac Surg 11:133-7. 2010
    ....
  3. ncbi Increased platelet, leukocyte and endothelial microparticles predict enhanced coagulation and vascular inflammation in pulmonary hypertension
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    J Thromb Thrombolysis 31:173-9. 2011
    ..02). PH patients have increased levels of platelet-, leukocyte- and endothelial MP indicating an increased vascular pro-coagulation and inflammation which might be related to thrombo-embolic complications as well as PH progression...
  4. ncbi Discontinuation of long term clopidogrel therapy induces platelet rebound hyperaggregability between 2 and 6 weeks post cessation
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, 79106 Freiburg, Germany
    Clin Res Cardiol 100:765-71. 2011
    ..Stent thrombosis occurs frequently within the first weeks after cessation of longterm clopidogrel therapy. We investigated if rebound platelet hyperreactivity occurs to provide a mechanism for this clinical observation...
  5. ncbi Increased levels of circulating microparticles in patients with severe aortic valve stenosis
    Philipp Diehl
    Dept for Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr 55, D 79106 Freiburg, Germany
    Thromb Haemost 99:711-9. 2008
    ....
  6. ncbi Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes
    Philipp Diehl
    Department of Cardiology and Angiology, University Hospital Freiburg, 79106 Freiburg, Germany
    Basic Res Cardiol 105:379-87. 2010
    ..This interaction is abolished by clopidogrel. Therefore, clopidogrel may act directly on leukocytes via the P2Y(12) receptor. (2) Clopidogrel may be under dosed in obese patients...
  7. ncbi BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1
    Thomas Helbing
    Department for Cardiology, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    Arterioscler Thromb Vasc Biol 30:554-60. 2010
    ..We set out to investigate the effect of statins on BMP endothelial cell precursor-derived regulator (BMPER), a novel member of the BMP pathway...
  8. ncbi Krüppel-like factor 15 regulates BMPER in endothelial cells
    Thomas Helbing
    Department of Cardiology, University of Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
    Cardiovasc Res 85:551-9. 2010
    ..BMPER is a key regulator of BMP4 activity and a prerequisite for BMP pathway activation by BMP4 in endothelial cells. Here, we characterize the BMPER promoter and elucidate mechanisms of BMPER regulation...
  9. ncbi [Is stent thrombosis the new Achilles heel of interventional cardiology? State of the Art clinical trials, causes and approaches for prevention]
    T Grumann
    Abteilung III für Kardiologie und Angiologie, Medizinische Universititäsklinik, Hugstetterstrasse 55, 79106 Freiburg
    Hamostaseologie 27:344-50. 2007
    ..Therefore, individual determination of platelet function in each patient undergoing stent implantation may help to avoid prothrombotic as well as bleeding complications...