Volker Daniel

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi request reprint CD4+ CD25+ Foxp3+ IFNγ+ CD178+ human induced Treg (iTreg) contribute to suppression of alloresponses by apoptosis of responder cells
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany
    Hum Immunol 74:151-62. 2013
  2. doi request reprint CD4(+)CD25(+)Foxp3(+)IFNγ(+) Treg are immunosuppressive in vitro and increase with intensity of the alloresponse in pretransplant MLC
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany
    Transpl Immunol 27:114-21. 2012
  3. pmc In-vitro inhibition of IFNγ+ iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Germany
    BMC Immunol 13:47. 2012
  4. ncbi request reprint Association of IL-12+ DC with High CD3+CD4-DR+ lymphocyte counts in long-term HIV-infected hemophilia patients with clinically stable disease
    Volker Daniel
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    J Clin Immunol 28:58-72. 2008
  5. ncbi request reprint Normal or even increased dendritic cell and peripheral blood lymphocyte subsets with regulatory phenotype in clinically stable long-term HIV-infected patients with hemophilia on highly active antiretroviral therapy
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    J Acquir Immune Defic Syndr 47:1-15. 2008
  6. doi request reprint Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transpl Int 21:646-60. 2008
  7. doi request reprint Association of high IFN-gamma plasma levels with low B-cell counts in renal transplant recipients with stable long-term graft function
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Clin Transplant 24:281-9. 2010
  8. ncbi request reprint Association of circulating interleukin (IL)-12- and IL-10-producing dendritic cells with time posttransplant, dose of immunosuppression, and plasma cytokines in renal-transplant recipients
    Volker Daniel
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, S 69120 Heidelberg, Germany
    Transplantation 79:1498-506. 2005
  9. ncbi request reprint Clinical relevance of immune monitoring in solid organ transplantation
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Int Rev Immunol 28:155-84. 2009
  10. doi request reprint CD4+CD25+Foxp3+IFN-γ+ human induced T regulatory cells are induced by interferon-γ and suppress alloresponses nonspecifically
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Hum Immunol 72:699-707. 2011

Collaborators

Detail Information

Publications54

  1. doi request reprint CD4+ CD25+ Foxp3+ IFNγ+ CD178+ human induced Treg (iTreg) contribute to suppression of alloresponses by apoptosis of responder cells
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany
    Hum Immunol 74:151-62. 2013
    ....
  2. doi request reprint CD4(+)CD25(+)Foxp3(+)IFNγ(+) Treg are immunosuppressive in vitro and increase with intensity of the alloresponse in pretransplant MLC
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany
    Transpl Immunol 27:114-21. 2012
    ..Quantity of induced IFNγ(+) iTreg depends on the strength of the alloresponse and both parameters are inversely associated with long-term graft outcome...
  3. pmc In-vitro inhibition of IFNγ+ iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Germany
    BMC Immunol 13:47. 2012
    ..To study the mechanism of immunosuppression, we attempted to block cell surface receptors and thereby inhibited the function of this iTreg subset in-vitro using monoclonal antibodies and recombinant proteins...
  4. ncbi request reprint Association of IL-12+ DC with High CD3+CD4-DR+ lymphocyte counts in long-term HIV-infected hemophilia patients with clinically stable disease
    Volker Daniel
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    J Clin Immunol 28:58-72. 2008
    ..These data suggest that long-term HIV-infected hemophilia patients with clinically stable disease have normal levels of functional IL-10(+) DC and IL-12(+) DC that might be involved in halting the progression of disease...
  5. ncbi request reprint Normal or even increased dendritic cell and peripheral blood lymphocyte subsets with regulatory phenotype in clinically stable long-term HIV-infected patients with hemophilia on highly active antiretroviral therapy
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    J Acquir Immune Defic Syndr 47:1-15. 2008
    ..Increased CD8 PBL counts imply immunocompetence. Increased CD8 PBL counts and normal or even upregulated immunoregulatory cells might stabilize our long-term HIV-infected patients with hemophilia clinically...
  6. doi request reprint Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transpl Int 21:646-60. 2008
    ..Our data support an immunoregulatory role of CD3+CD4+CD25+Foxp3+IFN-gamma+ cells in a subgroup of transplant recipients with good graft acceptance...
  7. doi request reprint Association of high IFN-gamma plasma levels with low B-cell counts in renal transplant recipients with stable long-term graft function
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Clin Transplant 24:281-9. 2010
    ..High IFN-gamma plasma levels might prevent the development of an immunological alloresponse and thereby contribute to the maintenance of graft acceptance...
  8. ncbi request reprint Association of circulating interleukin (IL)-12- and IL-10-producing dendritic cells with time posttransplant, dose of immunosuppression, and plasma cytokines in renal-transplant recipients
    Volker Daniel
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, S 69120 Heidelberg, Germany
    Transplantation 79:1498-506. 2005
    ..We investigated DC and plasma cytokine patterns early and late after transplantation...
  9. ncbi request reprint Clinical relevance of immune monitoring in solid organ transplantation
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Int Rev Immunol 28:155-84. 2009
    ..A multiparametric immune monitoring program, performed frequently and lifelong, might be the appropriate approach to predict dysfunction of the graft before clinical symptoms occur...
  10. doi request reprint CD4+CD25+Foxp3+IFN-γ+ human induced T regulatory cells are induced by interferon-γ and suppress alloresponses nonspecifically
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Hum Immunol 72:699-707. 2011
    ..Circulating CD4(+)CD25(+)Foxp3(+)IFN-γ(+) PBL could suppress allogeneic T-cell responses in patients and may be involved in inhibition of the posttransplant alloresponse...
  11. ncbi request reprint Associations of dichlorodiphenyltrichloroethane (DDT) 4.4 and dichlorodiphenyldichloroethylene (DDE) 4.4 blood levels with plasma IL-4
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Arch Environ Health 57:541-7. 2002
    ..The authors hypothesized that clinical symptoms, such as the frequent infections reported by many patients, could be a consequence of these immunological abnormalities...
  12. doi request reprint Increased peripheral blood leukocyte subsets with regulatory phenotype in clinically stable long-term HIV-infected hemophilia patients on HAART may be beneficial and contribute to a decrease in autoimmunity
    Volker Daniel
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Viral Immunol 23:87-97. 2010
    ..Increased immunoregulatory T PBL might decrease autoimmunity, thereby contributing to immunological reconstitution and stabilization of long-term HIV-infected hemophilia patients on HAART...
  13. pmc Proteasome inhibition suppresses essential immune functions of human CD4+ T cells
    Carsten Berges
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Immunology 124:234-46. 2008
    ..Thus, the proteasome is required for essential immune functions of activated CD4(+) T cells and can be defined as a molecular target for the suppression of deregulated and unwanted T-cell-mediated immune responses...
  14. ncbi request reprint Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    AIDS Res Hum Retroviruses 23:886-90. 2007
    ..Our data suggest that decreasing sCD30 and increasing IFN-gamma plasma levels are indicators of effective HAART treatment and CD4 Th1 cell recovery in HIV-infected patients...
  15. doi request reprint Decreasing plasma soluble IL-1 receptor antagonist and increasing monocyte activation early post-transplant may be involved in pathogenesis of delayed graft function in renal transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, D 69120 Heidelberg, Germany
    Clin Transplant 24:415-23. 2010
    ..Blocking of monocyte activity after renal transplantation may be considered a potential approach for improving graft outcome...
  16. doi request reprint Association of pretransplant soluble glycoprotein 130 (sgp130) plasma levels and posttransplant acute tubular necrosis in renal transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, D 69120 Heidelberg, Germany
    Transplantation 88:266-71. 2009
    ..Previously, we reported that high pretransplant sIL-6R plasma levels are associated with posttransplant acute tubular necrosis (ATN). In this study, we examined associations of pretransplant plasma levels of sgp130 with ATN...
  17. doi request reprint Proteasome inhibition activates the mitochondrial pathway of apoptosis in human CD4+ T cells
    Carsten Berges
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    J Cell Biochem 108:935-46. 2009
    ..These results provide novel insights into the mechanisms of apoptosis induced by proteasome inhibition in activated T cells and underscore the future use of proteasome inhibitors for immunosuppression...
  18. doi request reprint Helenalin suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms
    Carsten Berges
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    Mol Immunol 46:2892-901. 2009
    ..Thus, helenalin can be defined as a new immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses...
  19. doi request reprint Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 88:1109-16. 2009
    ..BKV-associated nephropathy develops in approximately 5% to 8% of renal transplant recipients, and its prognosis is poor. The relationship between urine cytokines and BK viruria in kidney recipients has not been defined...
  20. ncbi request reprint Dissociation of CD4(+) cell counts from viral load and association with immune complexes in HIV(+) hemophilia patients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120, Heidelberg, Germany
    Immunol Lett 91:23-32. 2004
    ..In this retrospective study, we investigated whether HIV causes CD4 depletion by direct cytotoxicity or indirectly by induction of a host autoimmune response...
  21. pmc Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells
    Cord Naujokat
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Immunology 120:120-32. 2007
    ....
  22. doi request reprint Plasmapheresis adjusts inflammatory responses in potential kidney transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 95:1021-9. 2013
    ..The effect of PP on lymphocyte subpopulations, plasma neopterin, and cytokines in renal transplant recipients was investigated in this study...
  23. ncbi request reprint Evidence for IFN-gamma up- and IL-4 downregulation late post-transplant in patients with good kidney graft outcome
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Clin Transplant 21:449-59. 2007
    ..These data suggest that increased plasma IFN-gamma and decreased plasma IL-4 late post-transplant might be involved in the induction of mechanisms that facilitate good long-term graft outcome...
  24. doi request reprint Increased pretransplantation plasma kynurenine levels do not protect from but predict acute kidney allograft rejection
    Imad Lahdou
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Hum Immunol 71:1067-72. 2010
    ..Although informative in overall terms, at the present stage, Kyn levels do not allow the concise risk differentiation of individual patients...
  25. doi request reprint Epidemiology of pretransplant EBV and CMV serostatus in relation to posttransplant non-Hodgkin lymphoma
    Gerhard Opelz
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 88:962-7. 2009
    ..CMV serostatus was not independently associated with risk of NHL after kidney transplantation. Surprisingly, in liver transplantation, the risk of NHL was virtually unaffected by EBV serostatus...
  26. doi request reprint Dysregulated cytokine responses during cytomegalovirus infection in renal transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 86:275-85. 2008
    ..The aim of this study was to examine whether there are differences in plasma cytokine levels pretransplant, before and during CMV replication in renal transplant recipients...
  27. ncbi request reprint Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transpl Int 18:177-85. 2005
    ....
  28. ncbi request reprint Antithymocyte globulins suppress dendritic cell function by multiple mechanisms
    Cord Naujokat
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 83:485-97. 2007
    ..Although immunosuppressive mechanisms of ATGs on T cells are well studied, less is known about their impact on dendritic cells (DCs)...
  29. ncbi request reprint Evaluation of hepatocyte growth factor as a sensitive marker for early detection of acute renal allograft rejection
    Khaled Mahmoud
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 83:1035-40. 2007
    ..In the present study we investigated whether HGF can serve as a marker for detection of acute rejection in the early posttransplantation period...
  30. doi request reprint HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway
    Dominik Fuchs
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    Biochem Biophys Res Commun 374:309-14. 2008
    ..Thus, simvastatin overcomes bortezomib-induced apoptosis resistance by inhibiting synthesis of GGPP and disrupting a GGPP-dependent survival pathway...
  31. ncbi request reprint Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells
    Dominik Fuchs
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, D 69120 Heidelberg, Germany
    J Cell Biochem 103:270-83. 2008
    ....
  32. doi request reprint Strong association of phenylalanine and tryptophan metabolites with activated cytomegalovirus infection in kidney transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, D 69117 Heidelberg, Germany
    Hum Immunol 73:186-92. 2012
    ..Moreover, tryptophan metabolite levels correlate with disease severity. Measurement of these amino acids is an inexpensive and fast method expected to complete conventional diagnostic assays...
  33. ncbi request reprint High urine sIL-6R as a predictor of late graft failure in renal transplant recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany mahmoud sadeghi med uni heidelberg de
    Transplantation 76:1190-4. 2003
    ..Chronic allograft nephropathy is an important cause of late renal transplant failure. Although numerous studies on cytokines have been carried out, the pathogenetic role of cytokines in chronic renal allograft nephropathy remains unclear...
  34. ncbi request reprint Association of high pretransplant sIL-6R plasma levels with acute tubular necrosis in kidney graft recipients
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 81:1716-24. 2006
    ....
  35. doi request reprint Increased serum levels of quinolinic acid indicate enhanced severity of hepatic dysfunction in patients with liver cirrhosis
    Imad Lahdou
    Department of Transplantation Immunology, University of Heidelberg, Germany
    Hum Immunol 74:60-6. 2013
    ..Here we investigate whether the degree of systemic inflammation (QuinA, neopterin, CRP and IL-6) correlates with clinical liver dysfunction according to the MELD Score...
  36. pmc Cytokine expression during early and late phase of acute Puumala hantavirus infection
    Mahmoud Sadeghi
    Department of Transplantation Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany
    BMC Immunol 12:65. 2011
    ..An immune-mediated pathogenesis is discussed for both syndromes. The aim of our study was to investigate cytokine expression during the course of acute Puumala hantavirus infection...
  37. doi request reprint Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells
    Dominik Fuchs
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    Biochem Biophys Res Commun 390:743-9. 2009
    ..Thus, salinomycin should be considered as a novel and effective anticancer agent that overcomes multiple mechanisms of apoptosis resistance in human cancer cells...
  38. doi request reprint Pharmacokinetics and immunodynamics of basiliximab in pediatric renal transplant recipients on mycophenolate mofetil comedication
    Britta Höcker
    Department of Pediatrics I, University Children s Hospital Heidelberg, Heidelberg, Germany
    Transplantation 86:1234-40. 2008
    ....
  39. ncbi request reprint Role of human corneal endothelial cells in T-cell-mediated alloimmune attack in vitro
    Imad Lahdou
    University Hospital Heidelberg, Department of Immunology, Heidelberg, Germany
    Invest Ophthalmol Vis Sci 55:1213-21. 2014
    ....
  40. ncbi request reprint Disassociation between risk of graft loss and risk of non-Hodgkin lymphoma with induction agents in renal transplant recipients
    Gerhard Opelz
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 81:1227-33. 2006
    ..It is widely assumed that the graft-enhancing properties of antilymphocyte induction agents and their lymphoma-inducing potential are intimately related...
  41. ncbi request reprint Cell cycle- and activation-dependent regulation of cyclosporin A-induced T cell apoptosis
    Cord Naujokat
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    Biochem Biophys Res Commun 310:347-54. 2003
    ....
  42. ncbi request reprint Effect of cytomegalovirus prophylaxis with immunoglobulin or with antiviral drugs on post-transplant non-Hodgkin lymphoma: a multicentre retrospective analysis
    Gerhard Opelz
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Lancet Oncol 8:212-8. 2007
    ..No reliable methods for the prevention of EBV infection and lymphoma are available. We aimed to elucidate the effect of prophylactic treatment for cytomegalovirus (CMV) infection on the incidence of post-transplant lymphomas...
  43. ncbi request reprint Longitudinal analysis of T-helper cell phenotypes in renal-transplant recipients undergoing growth hormone therapy
    Anette Melk
    Department of Transplantation Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 78:1792-801. 2004
    ..We therefore evaluated the immune phenotypes of pediatric renal-transplant recipients and controls in response to rhGH with regard to a possible shift toward a T-helper (TH)1-type response...
  44. ncbi request reprint A cell line model for the differentiation of human dendritic cells
    Carsten Berges
    Institute of Immunology, Department of Transplantation Immunology, University of Heidelberg, Im Neuenheimer Feld 305, D 69120 Heidelberg, Germany
    Biochem Biophys Res Commun 333:896-907. 2005
    ....
  45. doi request reprint The collaborative transplant study registry
    Gerhard Opelz
    Department of Transplantation Immunology, University of Heidelberg, D 61920 Heidelberg, Germany
    Transplant Rev (Orlando) 27:43-5. 2013
    ..Participation is voluntary and the study has strictly scientific objectives. Analyses of the CTS database serve as an international reference source in the field of solid organ transplantation...
  46. ncbi request reprint Effectivity of a T-cell-adapted induction therapy with anti-thymocyte globulin (Sangstat)
    Achim Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    J Heart Lung Transplant 24:708-13. 2005
    ..Therefore, we investigated whether reduced T-cell-adapted ATG induction therapy could be performed without increasing the risk of graft loss by rejection and whether reductions in infection rates and costs are possible...
  47. ncbi request reprint Interferon-gamma producing regulatory T cells as a diagnostic and therapeutic tool in organ transplantation
    Volker Daniel
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Int Rev Immunol 33:195-211. 2014
    ....
  48. ncbi request reprint Evaluation of posttransplantation soluble CD30 for diagnosis of acute renal allograft rejection
    Steffen Pelzl
    Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Transplantation 75:421-3. 2003
    ..Posttransplantation measurement of soluble CD30 (sCD30) may be useful for identifying kidney graft recipients at risk of impending graft rejection in the early posttransplantation period...
  49. doi request reprint The role of IL-8 in patients with fibromyalgia: a prospective longitudinal study of 6 months
    Haili Wang
    Department of Orthopedic Surgery, Ruprecht Karls University of Heidelberg, Heidelberg, Germany
    Clin J Pain 25:1-4. 2009
    ....
  50. doi request reprint Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency
    Johann Greil
    Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany
    J Allergy Clin Immunol 131:1376-83.e3. 2013
    ..They are clinically highly relevant per se because in patients with severe combined immunodeficiency (SCID), infections caused by opportunistic pathogens are typically life-threatening early in life...
  51. ncbi request reprint Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases
    Jakub Golab
    Department of Immunology, Center of Biostructure Research, The Medical University of Warsaw, Warsaw, Poland
    Clin Chim Acta 340:27-40. 2004
    ..Future research should lead to an improved understanding of the pathophysiology of the ubiquitin-proteasome pathway with the aim of allowing the development of subtle diagnostic strategies...
  52. ncbi request reprint ATG induction therapy: long-term effects on Th1 but not on Th2 responses
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transpl Int 18:226-36. 2005
    ....
  53. ncbi request reprint Mycophenolate mofetil-based immunosuppression and cytokine genotypes: effects on monokine secretion and antigen presentation in long-term renal transplant recipients
    Rolf Weimer
    Department of Internal Medicine, University of Giessen, Giessen, Germany
    Transplantation 75:2090-9. 2003
    ..It has been suggested that increased monocyte responses might play a role in chronic allograft rejection...