A Danek

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi The chorea of McLeod syndrome
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Munchen, Germany
    Mov Disord 16:882-9. 2001
  2. ncbi McLeod neuroacanthocytosis: genotype and phenotype
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Munchen, Germany
    Ann Neurol 50:755-64. 2001
  3. ncbi [Progress in molecular chorea diagnosis. McLeod syndrome and chorea acanthocytosis]
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Postfach 701260, 81366 München
    Nervenarzt 73:564-9. 2002
  4. ncbi Brain imaging and neuropsychology in late-onset dementia due to a novel mutation (R93C) of valosin-containing protein
    S Krause
    Neurologische Klinik, Ludwig Maximilians Universitat Munchen, Germany
    Clin Neuropathol 26:232-40. 2007
  5. pmc Reduction of striatal glucose metabolism in McLeod choreoacanthocytosis
    M Oechsner
    Neurologische Klinik, Universitaetsklinikum Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Neurol Neurosurg Psychiatry 70:517-20. 2001
  6. ncbi [Complexities of "reversible posterior leukoencephalopathy syndrome"]
    S Herberger
    Neurologische Klinik, Klinikum Grosshadern der LMU München, Marchioninistrasse 15, 81377, Munchen
    Nervenarzt 77:1218-22. 2006
  7. ncbi Obsessive-compulsive disorders due to neuroacanthocytosis treated with citalopram
    R H Walker
    1Department of Neurology, James J Peters Veterans Affairs Medical Center, Bronx, and Mount Sinai School of Medicine, New York, NY, USA
    Pharmacopsychiatry 40:132; author reply 132-3. 2007
  8. ncbi Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein
    M Ho
    Imperial Cancer Research Fund Laboratories, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, England
    Cell 77:869-80. 1994
  9. ncbi Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis
    C Dobson-Stone
    The Wellcome Trust Centre for Human Genetics, University of Oxford, UK
    Eur J Hum Genet 10:773-81. 2002
  10. ncbi A conserved sorting-associated protein is mutant in chorea-acanthocytosis
    L Rampoldi
    The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, United Kingdom
    Nat Genet 28:119-20. 2001

Collaborators

Detail Information

Publications18

  1. ncbi The chorea of McLeod syndrome
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Munchen, Germany
    Mov Disord 16:882-9. 2001
    ..This, together with the absence of dysphagia in McLeod syndrome, may help in differential diagnosis. Recent findings suggest a role for the endothelin system of the striatum in the pathogenesis of McLeod syndrome...
  2. ncbi McLeod neuroacanthocytosis: genotype and phenotype
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Munchen, Germany
    Ann Neurol 50:755-64. 2001
    ....
  3. ncbi [Progress in molecular chorea diagnosis. McLeod syndrome and chorea acanthocytosis]
    A Danek
    Neurologische Klinik, Ludwig Maximilians Universitat, Postfach 701260, 81366 München
    Nervenarzt 73:564-9. 2002
    ..Animal models are needed to understand the underlying mechanisms. A final common pathway is likely for the pathogenesis of these conditions and is most probably shared with Huntington's disease...
  4. ncbi Brain imaging and neuropsychology in late-onset dementia due to a novel mutation (R93C) of valosin-containing protein
    S Krause
    Neurologische Klinik, Ludwig Maximilians Universitat Munchen, Germany
    Clin Neuropathol 26:232-40. 2007
    ..This first comprehensive clinical and neuroimaging study in IBMPFD may raise the awareness among clinicians as well as basic scientists for this exemplary genetic model of dementia...
  5. pmc Reduction of striatal glucose metabolism in McLeod choreoacanthocytosis
    M Oechsner
    Neurologische Klinik, Universitaetsklinikum Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Neurol Neurosurg Psychiatry 70:517-20. 2001
    ..Frontal lobe metabolism was not affected. Basal ganglia dysfunction with early impairment of striatal glucose metabolism thus seems obligatory for McLeod syndrome, as found in other forms of chorea with or without acanthocytosis...
  6. ncbi [Complexities of "reversible posterior leukoencephalopathy syndrome"]
    S Herberger
    Neurologische Klinik, Klinikum Grosshadern der LMU München, Marchioninistrasse 15, 81377, Munchen
    Nervenarzt 77:1218-22. 2006
    ..The apparent diffusion coefficient helps to differentiate between reversible vasogenic edema and cytotoxic edema, the latter indicating irreversible neuronal death...
  7. ncbi Obsessive-compulsive disorders due to neuroacanthocytosis treated with citalopram
    R H Walker
    1Department of Neurology, James J Peters Veterans Affairs Medical Center, Bronx, and Mount Sinai School of Medicine, New York, NY, USA
    Pharmacopsychiatry 40:132; author reply 132-3. 2007
  8. ncbi Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein
    M Ho
    Imperial Cancer Research Fund Laboratories, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, England
    Cell 77:869-80. 1994
    ..Nucleotide sequence analysis of XK from two unrelated McLeod patients has identified point mutations at conserved splice donor and acceptor sites. These findings provide direct evidence that XK is responsible for McLeod syndrome...
  9. ncbi Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis
    C Dobson-Stone
    The Wellcome Trust Centre for Human Genetics, University of Oxford, UK
    Eur J Hum Genet 10:773-81. 2002
    ..The CHAC protein product, chorein, appears to have a certain tolerance to amino-acid substitutions since only two out of nine substitutions described here appear to be pathogenic...
  10. ncbi A conserved sorting-associated protein is mutant in chorea-acanthocytosis
    L Rampoldi
    The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, United Kingdom
    Nat Genet 28:119-20. 2001
    ..We identified a gene in the CHAC critical region and found 16 different mutations in individuals with chorea-acanthocytosis. CHAC encodes an evolutionarily conserved protein that is probably involved in protein sorting...
  11. ncbi [Type I neurofibromatosis. A model for the study of molecular principles of cognition]
    A Danek
    Neurologische Klinik und Poliklinik, , Klinikum Grosshadern, Marchioninistrasse 15,
    Nervenarzt 72:963-7. 2001
    ..In man, an early diagnosis of NF1 is presently essential in order to provide specific remedial education for children affected by the learning disorder of neurofibromatosis type I...
  12. pmc White matter abnormalities on MRI in neuroacanthocytosis
    D J Nicholl
    J Neurol Neurosurg Psychiatry 75:1200-1. 2004
  13. ncbi Neurologic phenotypes associated with acanthocytosis
    R H Walker
    Department of Neurology, James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Neurology 68:92-8. 2007
    ..As in other neurodegenerative conditions, animal models are a promising strategy for the development of such therapies...
  14. ncbi [Differential diagnosis of bilateral thalamic lesions]
    J Linn
    Abteilung fur Neuroradiologie, Universitätsklinikum München
    Rofo 179:234-45. 2007
    ..This review provides a synopsis of the radiological findings for the most important bithalamic lesions and an overview of the literature...
  15. pmc Chorea-acanthocytosis: genetic linkage to chromosome 9q21
    J P Rubio
    The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom
    Am J Hum Genet 61:899-908. 1997
    ..These findings provide strong evidence for the involvement of a single locus for CHAC and are the first step in positional cloning of the disease gene...
  16. ncbi Antisocial behaviour and neuroacanthocytosis
    A Danek
    Int J Clin Pract 61:1419; author reply 1419. 2007
  17. ncbi McLeod syndrome: a neurohaematological disorder
    H H Jung
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Vox Sang 93:112-21. 2007
    ..Therefore, asymptomatic carriers of the McLeod blood group phenotype should have a careful genetic counseling, neurological examination and a cardiologic evaluation for the presence of a treatable cardiomyopathy...
  18. ncbi [Cognitive impairment in adults with neurofibromatosis type 1]
    I Uttner
    Neurologische Klinik der Universität Ulm, Bereich RKU, Ulm
    Fortschr Neurol Psychiatr 71:157-62. 2003
    ..Observations are discussed in the context of studies investigating the association of cognitive deficits with either intracranial lesions or alterations in the neurofibromin expression...