Maura Dandri

Summary

Affiliation: University Medical Center Hamburg-Eppendorf
Country: Germany

Publications

  1. ncbi Experimental models and therapeutic approaches for HBV
    Maura Dandri
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Semin Immunopathol 35:7-21. 2013
  2. ncbi New insight in the pathobiology of hepatitis B virus infection
    Maura Dandri
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, D 20246, Hamburg, Germany
    Gut 61:i6-17. 2012
  3. ncbi In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
    Marc Lutgehetmann
    Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Hepatology 52:16-24. 2010
  4. ncbi Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia
    Maura Dandri
    Department of Medicine, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Hepatology 48:1079-86. 2008
  5. ncbi Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
    Marc Lutgehetmann
    Department of Internal Medicine, University Medical Hospital Hamburg Eppendorf, Hamburg, Germany
    Hepatology 55:685-94. 2012
  6. ncbi Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice
    Tassilo Volz
    Department of Internal Medicine, University Medical Center Hamburg, Hamburg, Germany
    Antivir Ther 17:623-31. 2012
  7. ncbi Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice
    Marc Lutgehetmann
    Department of Internal Medicine, University Medical Hospital Hamburg Eppendorf, Hamburg, Germany
    Gastroenterology 140:2074-83, 2083.e1-2. 2011
  8. ncbi The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
    Tassilo Volz
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Hepatol 58:861-7. 2013
  9. ncbi Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients
    Tassilo Volz
    Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Gastroenterology 133:843-52. 2007
  10. ncbi Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    Karsten Wursthorn
    Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany
    Hepatology 44:675-84. 2006

Collaborators

  • Ansgar W Lohse
  • John M Murray
  • Jorg Petersen
  • Gisa Tiegs
  • Gabriele Sass
  • Matthias Ocker
  • Smadar Cohen
  • Daniel Benten
  • Thomas Longerich
  • Karsten Wursthorn
  • Tassilo Volz
  • Marc Lutgehetmann
  • Lena Allweiss
  • Joerg M Pollok
  • Jeanette Bierwolf
  • Michael Warlich
  • Stephan Urban
  • Janine Kah
  • Till Bornscheuer
  • Kristoffer Weber
  • Eva Török
  • Jörg M Pollok
  • Alexander Alexandrov
  • Mounira Ben M Barek
  • Joerg Matthias Pollok
  • Huseyin Sirma
  • Eckart Matthes
  • Andrea Wüstenberg
  • Johannes Erbes
  • Martina Helbig
  • Bjoern Nashan
  • Lida V Mancke
  • Roberta Montalbano
  • Amelie Dorothea Keller
  • Steffen Deichmann
  • Boris Fehse
  • Maike Täger
  • Jörg Matthias Pollok
  • Jan Hendrick Bockmann
  • Kerstin Cornils
  • Michael Thomaschewski
  • Carol Stocking
  • Birte Niebuhr
  • Eberhard Fuchs
  • Eike Tigges
  • Tim Broja
  • Anne Köpke
  • Alexander Quaas
  • Anna Jacob
  • Paul Wachtler
  • Jochen Düllmann
  • Joerg-M Pollok
  • Xavier Rogiers
  • Klaus Siebert
  • Peter X Ma
  • Christian Vogel
  • Martin R Burda

Detail Information

Publications15

  1. ncbi Experimental models and therapeutic approaches for HBV
    Maura Dandri
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Semin Immunopathol 35:7-21. 2013
    ....
  2. ncbi New insight in the pathobiology of hepatitis B virus infection
    Maura Dandri
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, D 20246, Hamburg, Germany
    Gut 61:i6-17. 2012
    ....
  3. ncbi In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
    Marc Lutgehetmann
    Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Hepatology 52:16-24. 2010
    ..5-log loss of intrahepatic cccDNA loads (P = 0.02). Intrahepatic viral DNA sequences persisting at the end of the study were mostly present as replicative intermediates and not as integrated virus...
  4. ncbi Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia
    Maura Dandri
    Department of Medicine, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Hepatology 48:1079-86. 2008
    ..Notably, the lack of correlation between virion half-life and viremia in mice indicated that immune components significantly accelerate virion clearance rates in individuals with low titers...
  5. ncbi Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
    Marc Lutgehetmann
    Department of Internal Medicine, University Medical Hospital Hamburg Eppendorf, Hamburg, Germany
    Hepatology 55:685-94. 2012
    ..Treatment with the HBV entry inhibitor Myrcludex-B, efficiently hindered the establishment of HDV infection in vivo...
  6. ncbi Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice
    Tassilo Volz
    Department of Internal Medicine, University Medical Center Hamburg, Hamburg, Germany
    Antivir Ther 17:623-31. 2012
    ..The aim of this study was to determine the antiviral activity of l-Hyd4FC in HBV-infected human liver chimeric urokinase plasminogen activator (uPA)/SCID mice...
  7. ncbi Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice
    Marc Lutgehetmann
    Department of Internal Medicine, University Medical Hospital Hamburg Eppendorf, Hamburg, Germany
    Gastroenterology 140:2074-83, 2083.e1-2. 2011
    ..We investigated whether HBV infection reduced IFN-α-mediated induction of antiviral defense mechanisms in human hepatocytes...
  8. ncbi The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
    Tassilo Volz
    Department of Internal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Hepatol 58:861-7. 2013
    ..We aimed at investigating the ability of the lipopeptide Myrcludex-B to block HBV spreading post-infection...
  9. ncbi Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients
    Tassilo Volz
    Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Gastroenterology 133:843-52. 2007
    ....
  10. ncbi Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    Karsten Wursthorn
    Department of Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany
    Hepatology 44:675-84. 2006
    ..In conclusion, combination therapy with peg-IFN and ADV led to marked decreases in serum HBV-DNA and intrahepatic cccDNA, which was significantly correlated with reduced HBsAg...
  11. ncbi Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds
    Jeanette Bierwolf
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Tissue Eng Part A 18:1443-53. 2012
    ..Further, we demonstrate that livers from children with inherited metabolic disorders could serve as an alternative cell source for in vitro experiments...
  12. ncbi RGB marking facilitates multicolor clonal cell tracking
    Kristoffer Weber
    Research Department Cell and Gene Therapy, Clinic for Stem Cell Transplantation, University Cancer Center Hamburg, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Nat Med 17:504-9. 2011
    ..We conclude that RGB marking represents a useful tool for cell clonality studies in tissue regeneration and pathology...
  13. ncbi Morphological and functional analysis of rat hepatocyte spheroids generated on poly(L-lactic acid) polymer in a pulsatile flow bioreactor
    Eva Török
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Tissue Eng 12:1881-90. 2006
    ..Pulsatile flow culture on PLLA scaffolds is a promising new method of hepatic tissue engineering leading to liver neo-tissue formation...
  14. ncbi Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression
    Janine Kah
    Institute of Experimental Immunology and Hepatology, Department of Medicine I, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Oncol Rep 28:1077-83. 2012
    ..Additionally, our results implicate that anti-tumor activity of statins requires cell proliferation and is reduced by p53 overexpression...
  15. ncbi Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
    Maura Dandri
    Heinrich Pette Institute for Experimental Virology and Immunology, University of Hamburg, Hamburg, Germany
    Hepatology 35:217-23. 2002
    ....