C Cursiefen

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. doi request reprint Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study
    Claus Cursiefen
    Department of Ophthalmology, University of Cologne, Cologne, Germany Electronic address
    Ophthalmology 121:1683-92. 2014
  2. doi request reprint [Descemetectomy as therapy option for visually disturbing roll in Descemet's membrane]
    C Cursiefen
    Zentrum für Augenheilkunde, Klinik und Poliklinik für Allgemeine Augenheilkunde, Universitat zu Koln, Deutschland
    Ophthalmologe 110:872-5. 2013
  3. doi request reprint [Prevention and management of complications in Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK)]
    C Cursiefen
    Universitätsaugenklinik Köln, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
    Ophthalmologe 110:614-21. 2013
  4. doi request reprint [Anti(lymph)angiogenic preconditioning prior to keratoplasty]
    C Cursiefen
    Universitatsaugenklinik, Universitat zu Koln, Kerpener Strasse 62, Koln
    Klin Monbl Augenheilkd 230:500-4. 2013
  5. doi request reprint [Perspectives of deep anterior lamellar keratoplasty]
    C Cursiefen
    Augenklinik des Universitätsklinikums Köln, Universitat zu Koln, Joseph Stelzmann Str 9, 50924, Koln, Deutschland
    Ophthalmologe 108:833-9. 2011
  6. doi request reprint Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable
    Claus Cursiefen
    Department of Ophthalmology, University of Cologne, Joseph Stelzmann Strasse 9 50924, Cologne, Germany
    Br J Ophthalmol 96:3-9. 2012
  7. doi request reprint Age-related changes in murine limbal lymphatic vessels and corneal lymphangiogenesis
    D Hos
    Department of Ophthalmology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen, Germany
    Exp Eye Res 87:427-32. 2008
  8. ncbi request reprint Ocular findings in ichthyosis follicularis, atrichia, and photophobia syndrome
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Arch Ophthalmol 117:681-4. 1999
  9. doi request reprint Regression of mature lymphatic vessels in the cornea by photodynamic therapy
    F Bucher
    Department of Ophthalmology, University of Cologne, Cologne, Germany
    Br J Ophthalmol 98:391-5. 2014
  10. ncbi request reprint Adenoma of the nonpigmented ciliary epithelium mimicking a malignant melanoma of the iris
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Arch Ophthalmol 117:113-6. 1999

Detail Information

Publications28

  1. doi request reprint Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study
    Claus Cursiefen
    Department of Ophthalmology, University of Cologne, Cologne, Germany Electronic address
    Ophthalmology 121:1683-92. 2014
    ..We aimed to confirm these results in a phase III study and investigated a potential clinical benefit on visual acuity (VA), quality of life (QoL), and need for transplantation...
  2. doi request reprint [Descemetectomy as therapy option for visually disturbing roll in Descemet's membrane]
    C Cursiefen
    Zentrum für Augenheilkunde, Klinik und Poliklinik für Allgemeine Augenheilkunde, Universitat zu Koln, Deutschland
    Ophthalmologe 110:872-5. 2013
    ..The aim was to demonstrate the feasibility of targeted removal of a central visually disturbing roll in Descemet's membrane after complicated cataract surgery...
  3. doi request reprint [Prevention and management of complications in Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK)]
    C Cursiefen
    Universitätsaugenklinik Köln, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
    Ophthalmologe 110:614-21. 2013
    ..The aim of this article is to describe strategies to prevent and manage complications in DMEK and DSAEK surgery...
  4. doi request reprint [Anti(lymph)angiogenic preconditioning prior to keratoplasty]
    C Cursiefen
    Universitatsaugenklinik, Universitat zu Koln, Kerpener Strasse 62, Koln
    Klin Monbl Augenheilkd 230:500-4. 2013
    ..The aim of this study is to describe novel therapeutic concepts to promote graft survival in high-risk keratoplasty by targeting (lymph)angiogenesis in the transplant context...
  5. doi request reprint [Perspectives of deep anterior lamellar keratoplasty]
    C Cursiefen
    Augenklinik des Universitätsklinikums Köln, Universitat zu Koln, Joseph Stelzmann Str 9, 50924, Koln, Deutschland
    Ophthalmologe 108:833-9. 2011
    ..The current indications, techniques, results and complications of deep anterior lamellar keratoplasty are described...
  6. doi request reprint Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable
    Claus Cursiefen
    Department of Ophthalmology, University of Cologne, Joseph Stelzmann Strasse 9 50924, Cologne, Germany
    Br J Ophthalmol 96:3-9. 2012
    ..In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs...
  7. doi request reprint Age-related changes in murine limbal lymphatic vessels and corneal lymphangiogenesis
    D Hos
    Department of Ophthalmology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen, Germany
    Exp Eye Res 87:427-32. 2008
    ..The lower lymphangiogenic potency of older mice may explain the better outcome of corneal transplantations in old recipients, supporting the concept that lymphangiogenesis is an important risk-factor for corneal transplant rejection...
  8. ncbi request reprint Ocular findings in ichthyosis follicularis, atrichia, and photophobia syndrome
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Arch Ophthalmol 117:681-4. 1999
    ..A defective tear film, recurrent atopic keratoconjunctival inflammations, or a primary anomaly of corneal epithelial adhesion are potential causes for the corneal defects. Photophobia is most likely due to corneal abnormalities...
  9. doi request reprint Regression of mature lymphatic vessels in the cornea by photodynamic therapy
    F Bucher
    Department of Ophthalmology, University of Cologne, Cologne, Germany
    Br J Ophthalmol 98:391-5. 2014
    ..Therefore we analysed the possibility to regress corneal lymphatic vessels by photodynamic therapy (PDT), after intrastromal verteporfin injection...
  10. ncbi request reprint Adenoma of the nonpigmented ciliary epithelium mimicking a malignant melanoma of the iris
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Arch Ophthalmol 117:113-6. 1999
    ..Postoperative visual acuity was 20/40 OD after 6 weeks. An adenoma of the nonpigmented ciliary epithelium may mimic an amelanotic malignant melanoma of the iris and should be considered in its differential diagnosis...
  11. doi request reprint [Immune reactions after DMEK, DSAEK and DALK]
    P Steven
    Zentrum für Augenheilkunde, Universität zu Köln Kerpener Strasse 62, Koln
    Klin Monbl Augenheilkd 230:494-9. 2013
    ..The aim of this study is to describe incidence, diagnosis and therapy for endothelial immune reactions after modern lamellar corneal transplantat surgery (DMEK, DSAEK, DALK)...
  12. doi request reprint "OSMO-UT-DSAEK" using THIN-C medium
    F Bucher
    Department of Ophthalmology, University of Cologne, Kerpenerstraße 62, 50924, Cologne, Germany
    Graefes Arch Clin Exp Ophthalmol 251:2181-5. 2013
    ..The aim of this study was to investigate whether additional osmotic deswelling prior to UT-DSAEK improves the quality of the cut surface and leads to a more reliable and deeper cut in UT-DSAEK ("OSMO-UT-DSAEK")...
  13. pmc Tumour-associated lymphangiogenesis in conjunctival malignant melanoma
    P Zimmermann
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Br J Ophthalmol 93:1529-34. 2009
    ..To evaluate whether tumour-associated lymphangiogenesis, that is the formation of new lymphatic vessels (LVs) induced by a tumour, occurs in and around conjunctival malignant melanoma (MM)...
  14. ncbi request reprint Bilateral zonular cataract associated with the mitochondrial cytopathy of Pearson syndrome
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Am J Ophthalmol 125:260-1. 1998
    ..To report a child with the mitochondrial cytopathy of Pearson syndrome and zonular cataract...
  15. ncbi request reprint Impact of short-term versus long-term topical steroids on corneal neovascularization after non-high-risk keratoplasty
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University, Erlangen Nurnberg, Germany
    Graefes Arch Clin Exp Ophthalmol 239:514-21. 2001
    ....
  16. doi request reprint [Long-term outcome after penetrating keratoplasty for bullous keratopathy - influence of preoperative visual acuity on final outcome]
    A Reimer
    Zentrum für Augenheilkunde, Universitat zu Koln, Koln
    Klin Monbl Augenheilkd 229:149-57. 2012
    ....
  17. ncbi request reprint Ocular findings in Fryns syndrome
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Acta Ophthalmol Scand 78:710-3. 2000
    ..The prevalence is about 0.7 per 10,000 births. Reported ocular features include microphthalmus, "cloudy cornea", irregularities of Bowman's layer, thickened posterior lens capsule and retinal dysplasia...
  18. ncbi request reprint Immunohistochemical localization of vascular endothelial growth factor, transforming growth factor alpha, and transforming growth factor beta1 in human corneas with neovascularization
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nurnberg, Germany
    Cornea 19:526-33. 2000
    ..To analyze presence and distribution of vascular endothelial growth factor (VEGF), transforming growth factor (TGF)alpha, and TGFbeta1 in human corneas with neovascularization due to different corneal diseases...
  19. doi request reprint Improved semiautomatic method for morphometry of angiogenesis and lymphangiogenesis in corneal flatmounts
    F Bock
    Department of Ophthalmology, University of Erlangen Nurnberg, Germany
    Exp Eye Res 87:462-70. 2008
    ..Therefore the semiautomatic method can be used to detect even small effects on hem and lymphangiogenesis in murine corneal flatmounts with greater precision...
  20. ncbi request reprint Oculocerebral non-Hodgkin's lymphoma with uveal involvement: development of an epibulbar tumor after vitrectomy
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Arch Ophthalmol 118:1437-40. 2000
    ..We conclude that, following vitrectomy, a primary ocular lymphoma may extend through the sclerotomy lesion and present as an epibulbar tumor. Uveal involvement may occur in oculocerebral non-Hodgkin's lymphoma...
  21. doi request reprint [Current aspects of eyelid, lacrimal and orbital surgery in childhood]
    G Avgitidou
    Zentrum für Augenheilkunde, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
    Ophthalmologe 112:102-9. 2015
    ..During childhood the spectrum of disorders of the eyelid, the lacrimal drainage system and the orbit as well as the subsequent therapeutic management differ from those in adults...
  22. doi request reprint [Decellularized collagen matrix from tilapia fish scales for corneal reconstruction (BioCornea)]
    D Hos
    Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str 62, 50924, Koln, Deutschland
    Ophthalmologe 111:1027-32. 2014
    ..The worldwide need for donor corneal tissue clearly exceeds the availability of transplantable human tissue; therefore, recent efforts aim to identify and characterize alternative tissues, such as decellularized collagen scaffolds...
  23. doi request reprint [Pediatric corneal surgery and corneal transplantation]
    B Bachmann
    Zentrum für Augenheilkunde, Universitat zu Koln, Kerpenerstr 62, 50937, Koln, Deutschland
    Ophthalmologe 112:110-7. 2015
    ..Moreover, posterior lamellar keratoplasty in children offers a faster visual recovery compared to penetrating keratoplasty and thus reduces the risk of amblyopia. ..
  24. pmc Two-step retrograde closed stenting: a novel method for treating canalicular lacerations in Chinese patients
    Y Bi
    1 Department of Ophthalmology, Tongji Hospital affiliated with Tongji University School of Medicine, Shanghai, China 2 Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany
    Eye (Lond) 27:1275-80. 2013
    ..The second step was canalicular anastomosis, which was performed in the operating room. In the one-step group (25 cases), all of the surgical procedures were performed when preoperative preparations were simultaneously available...
  25. ncbi request reprint Persisting retinal ganglion cell axons in blind atrophic human eyes
    C Cursiefen
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Graefes Arch Clin Exp Ophthalmol 239:158-64. 2001
    ..To evaluate enucleated blind atrophic human eyes for the persistence of retinal ganglion cell axons. This might be of relevance for contact to an electronic prosthesis in the future...
  26. doi request reprint [Significance of transcanalicular laser assisted dacryocystorhinostomy in modern lacrimal drainage surgery]
    K R Koch
    Zentrum für Augenheilkunde, Universitätsklinikum Köln, 50924, Koln, Deutschland
    Ophthalmologe 112:122-6. 2015
    ..Published success rates of 70-90% get close to the excellent results of Toti procedures. Besides describing therapy planning and surgical technique, pros and cons of TCL-DCR are discussed...
  27. doi request reprint [Glaucoma and dry eye. Current concepts and future perspectives]
    P Steven
    Universitätsaugenklinik Köln, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
    Ophthalmologe 110:1155-9. 2013
    ..Current concepts and future perspectives for therapy and prevention of dry eye in glaucoma patients are described...
  28. ncbi request reprint Recurrent optic nerve head infarctions associated with combined factor V Leiden- and factor II:G20210A-mutation
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Acta Ophthalmol Scand 77:625-7. 1999
    ..To demonstrate the association of bilateral recurrent optic nerve head infarctions with thrombophilia due to combined factor V:R506Q- and factor II:G20210A-mutation...