S Chrubasik

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi request reprint A 1-year follow-up after a pilot study with Doloteffin for low back pain
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 12:1-9. 2005
  2. doi request reprint [German version of a validated instrument to measure the quality of life in patients with hypertension]
    C Chrubasik
    Institut für Rechtsmedizin der Universität Freiburg
    Gesundheitswesen 74:488-95. 2012
  3. pmc Harpgophytum procumbens for osteoarthritis and low back pain: a systematic review
    Joel J Gagnier
    Department of Health Policy Management and Evaluation, University of Toronto, Faculty of Medicine, Toronto, Canada
    BMC Complement Altern Med 4:13. 2004
  4. ncbi request reprint Expressing treatment-associated changes
    S Chrubasik
    Institute of Forensic Medicine, University of Freiburg, 79104 Freiburg, Germany
    Z Rheumatol 64:423-7. 2005
  5. ncbi request reprint Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 12:684-701. 2005
  6. ncbi request reprint Efficacy and tolerability of potato juice in dyspeptic patients: a pilot study
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 13:11-5. 2006
  7. ncbi request reprint Patient-perceived benefit during one year of treatment with Doloteffin
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 14:371-6. 2007
  8. doi request reprint The clinical effectiveness of chokeberry: a systematic review
    C Chrubasik
    Braun School of Public Health, Hadassah Medical Center, Hebrew University, Jerusalem, Israel
    Phytother Res 24:1107-14. 2010
  9. doi request reprint Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain
    S Chrubasik
    Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytother Res 24:1877-85. 2010
  10. doi request reprint Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat
    Sigrun Chrubasik
    Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104, Freiburg, Germany
    Eur Arch Otorhinolaryngol 269:571-7. 2012

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A 1-year follow-up after a pilot study with Doloteffin for low back pain
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 12:1-9. 2005
    ..To complete a year's follow-up on patients from a 6-week double-blind pilot comparison between 44 Doloteffin patients and 44 rofecoxib patients being treated for acute exacerbations of chronic low back pain...
  2. doi request reprint [German version of a validated instrument to measure the quality of life in patients with hypertension]
    C Chrubasik
    Institut für Rechtsmedizin der Universität Freiburg
    Gesundheitswesen 74:488-95. 2012
    ....
  3. pmc Harpgophytum procumbens for osteoarthritis and low back pain: a systematic review
    Joel J Gagnier
    Department of Health Policy Management and Evaluation, University of Toronto, Faculty of Medicine, Toronto, Canada
    BMC Complement Altern Med 4:13. 2004
    ..The objective of this review is to determine the effectiveness of Harpagophytum procumbens preparations in the treatment of various forms of musculoskeletal pain...
  4. ncbi request reprint Expressing treatment-associated changes
    S Chrubasik
    Institute of Forensic Medicine, University of Freiburg, 79104 Freiburg, Germany
    Z Rheumatol 64:423-7. 2005
    ..Until they do, authors should justify their choice of expression, particularly if it critically influences their conclusion, and/or present their data as fully as possible on a website...
  5. ncbi request reprint Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 12:684-701. 2005
    ..Pharmacokinetic data are only available for [6]-gingerol and zingiberene. Preclinical safety data do not rule out potential toxicity, which should be monitored especially following ginger consumption over longer periods...
  6. ncbi request reprint Efficacy and tolerability of potato juice in dyspeptic patients: a pilot study
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 13:11-5. 2006
    ..However, placebo-controlled studies with a longer treatment period are needed to confirm this...
  7. ncbi request reprint Patient-perceived benefit during one year of treatment with Doloteffin
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytomedicine 14:371-6. 2007
    ..Adverse events were few and none were serious...
  8. doi request reprint The clinical effectiveness of chokeberry: a systematic review
    C Chrubasik
    Braun School of Public Health, Hadassah Medical Center, Hebrew University, Jerusalem, Israel
    Phytother Res 24:1107-14. 2010
    ....
  9. doi request reprint Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain
    S Chrubasik
    Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytother Res 24:1877-85. 2010
    ..The results indicate that capsaicin cream is useful in patients with chronic soft tissue pain and is also efficacious in patients with chronic back pain for which effectiveness was already demonstrated in earlier clinical trials...
  10. doi request reprint Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat
    Sigrun Chrubasik
    Institute of Forensic Medicine, University of Freiburg, Albertstr 9, 79104, Freiburg, Germany
    Eur Arch Otorhinolaryngol 269:571-7. 2012
    ..Adverse events were not observed. Benzocaine lozenges are superior to placebo lozenges and a useful, well-tolerated treatment option to reduce painful pharyngeal discomfort...
  11. ncbi request reprint [Devil's claw extract as an example of the effectiveness of herbal analgesics]
    S Chrubasik
    Institut für Rechtsmedizin der Universität Freiburg
    Orthopade 33:804-8. 2004
    ..Treatment with devil's claw extract is associated with a lower risk of adverse events than treatment with synthetic analgesics, and may contribute in the majority of patients to the relief of pain...
  12. ncbi request reprint The quality of clinical trials with Harpagophytum procumbens
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Freiburg, Germany
    Phytomedicine 10:613-23. 2003
    ..To examine systematically the quality of the clinical trials investigating the effectiveness of Harpagophytum products...
  13. ncbi request reprint A randomized double-blind pilot study comparing Doloteffin and Vioxx in the treatment of low back pain
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, 79104 Freiburg, Germany
    Rheumatology (Oxford) 42:141-8. 2003
    ....
  14. ncbi request reprint Comparison of outcome measures during treatment with the proprietary Harpagophytum extract doloteffin in patients with pain in the lower back, knee or hip
    S Chrubasik
    Department of Forensic Medicine, University of Freiburg, Germany
    Phytomedicine 9:181-94. 2002
    ..Between 50% and 70% of the patients benefitted from Doloteffin with few adverse effects. Thus, Doloteffin is well worth considering for osteoarthritic knee and hip pain and nonspecific low back pain...
  15. ncbi request reprint Potential economic impact of using a proprietary willow bark extract in outpatient treatment of low back pain: an open non-randomized study
    S Chrubasik
    Institut fur Rechtsmedizin, University of Freiburg, Germany
    Phytomedicine 8:241-51. 2001
    ..Substituting established NSAIDs with COX-2 inhibitors might reduce the side effects, but at greater cost than with the Assalix...
  16. doi request reprint A one-year survey on the use of a powder from Rosa canina lito in acute exacerbations of chronic pain
    C Chrubasik
    Department of Forensic Medicine, University of Freiburg, Albertstr 9, 79104 Freiburg, Germany
    Phytother Res 22:1141-8. 2008
    ..There were no serious adverse events. The rose hip and seed powder, Litozin, seems to deserve further, more definitive studies as a possible option in long-term management of NSLBP with or without osteoarthritic pain...
  17. ncbi request reprint Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain
    J E Chrubasik
    Institute of Forensic Medicine, University of Freiburg im Breisgau, Albertstr 9 79104 Freiburg im Breisgau, Germany
    Phytother Res 21:675-83. 2007
    ....
  18. ncbi request reprint The evidence for clinical efficacy of rose hip and seed: a systematic review
    C Chrubasik
    Institute of Forensic Medicine, University of Freiburg i Br, Albertstr 9, 79104 Freiburg i Br, Germany
    Phytother Res 20:1-3. 2006
    ..The objective of this review is to evaluate whether clinical research has gained any evidence of effectiveness of Rosa canina preparations...
  19. ncbi request reprint Physicochemical properties of harpagoside and its in vitro release from Harpagophytum procumbens extract tablets
    S Chrubasik
    Institut fur Pharmazeutische Biologie, University of Heidelberg, Germany
    Phytomedicine 6:469-73. 2000
    ..5 mg of harpagoside per dose. Harpagoside content decreased by about 10% in artificial gastric fluid within a period of 3 hours and remained stable in artificial intestinal fluid for a period of 6 hours...
  20. ncbi request reprint Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitro
    B L Fiebich
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    Phytomedicine 11:135-8. 2004
    ..Our data further suggest that the proprietary Salix extract is a weak inhibitor of proinflammatory cytokines...
  21. ncbi request reprint Potential molecular basis of the chondroprotective effect of Harpagophytum procumbens
    J E Chrubasik
    Phytomedicine 13:598-600. 2006
  22. ncbi request reprint Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back pain
    S Chrubasik
    Herbal Medicines Research and Education Centre, University of Sydney, Sydney, NSW 2006, Australia
    Rheumatology (Oxford) 40:1388-93. 2001
    ..Treatment with rofecoxib was about 40% more expensive than that with Assalix. CONCLUSION: There was no significant difference in effectiveness between the two treatments at the doses chosen. Treatment with Assalix was less expensive...
  23. ncbi request reprint Addendum to the ESCOP monograph on Harpagophytum procumbens
    S Chrubasik
    Phytomedicine 11:691-5; author reply 696. 2004
  24. ncbi request reprint Addendum to a recent systematic review on ginger
    S Chrubasik
    Forsch Komplementarmed Klass Naturheilkd 12:168; author reply 168-9. 2005
  25. doi request reprint Systematic review on the safety of Harpagophytum preparations for osteoarthritic and low back pain
    J Vlachojannis
    Department of Orthodontics, Columbia University, 630 W 168th, VC 9, Rm 219 B 10032 NYC, NY, USA
    Phytother Res 22:149-52. 2008
    ..Since the dosage used in most of the studies is at the lower limit and since long-term treatment with Harpagophytum products is advisable, more safety data are urgently needed...
  26. ncbi request reprint Impact of herbal medicines on physical impairment
    C Chrubasik
    Abteilung für Rheumatologie und klinische Immunologie, Kerckhoff Klinik Bad Nauheim Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie der Justus Liebig Universität Giessen, Benekestr 2 8, D 61231 Bad Nauheim, Germany
    Phytomedicine 15:536-9. 2008
    ..There may be little to lose from omitting the time-consuming assessments of "physical impairment" in studies of the (primarily analgesic) effectiveness of herbal preparations...
  27. ncbi request reprint Effectiveness of devil's claw for osteoarthritis
    S Chrubasik
    Rheumatology (Oxford) 41:1332-3; author reply 1333. 2002
  28. ncbi request reprint Different views of health care professionals on the treatment of osteoarthritis including low back pain
    S Chrubasik
    Rheumatology (Oxford) 42:1020-1. 2003
  29. ncbi request reprint Further evidence on the effectiveness of potato juice in dyspeptic complaints
    S Chrubasik
    Phytomedicine 13:596-7. 2006
  30. ncbi request reprint Effectiveness of Petasites hybridus preparations in the prophylaxis of migraine: a systematic review
    R Agosti
    Headache Center Hirslanden, Münchhaldenstr 33, 8008 Zurich, Switzerland
    Phytomedicine 13:743-6. 2006
    ....
  31. ncbi request reprint [Effectiveness of herbal drugs]
    S Chrubasik
    Forsch Komplementarmed Klass Naturheilkd 10:40-1. 2003
  32. ncbi request reprint Harpagophytum extracts
    S Chrubasik
    Clin Pharmacol Ther 71:104-5. 2002
  33. ncbi request reprint Vitamin E for rheumatoid arthritis or osteoarthritis: low evidence of effectiveness
    S Chrubasik
    Z Rheumatol 62:491. 2003