Research Topics
| B ChristSummaryAffiliation: University of Freiburg Country: Germany Publications
| Collaborators
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Detail Information
Publications
The development of the avian vertebral columnB Christ
Institute of Anatomy, University of Freiburg, Germany
Anat Embryol (Berl) 202:179-94. 2000..The development of the vertebral column is a consequence of a segment-specific balance between proliferation, apoptosis and differentiation of cells...- SF/HGF is a mediator between limb patterning and muscle developmentM Scaal
Institute of Anatomy, University of Freiburg, Albertstrasse 17, D 79104 Freiburg, Germany
Development 126:4885-93. 1999..We present a model for a crucial role of SF/HGF during migration and early patterning of muscle precursor cells in the vertebrate limb... - Expression pattern of BMPs during chick limb developmentP Geetha-Loganathan
Institute of Anatomy and Cell Biology, University of Freiburg, Albertstrasse 17, 79104, Freiburg, Germany
Anat Embryol (Berl) 211:87-93. 2006..All these BMPs are found to be expressed in the developing feather buds from day 8 onwards... - Regulation of Epha4 expression in paraxial and lateral plate mesoderm by ectoderm-derived signalsC Schmidt
Institut of Anatomy, University of Freiburg, D-79001 Freiburg, Germany
Dev Dyn 220:377-86. 2001..We suggest that signaling occurs between the somites and the lateral plate mesoderm and provide evidence that retinoic acid is involved in this communication... - Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesisF Prols
Institute of Anatomy II, Albert Ludwigs University, Freiburg, 79104, Germany
Exp Cell Res 269:42-53. 2001..These data suggest that Mdg1 is involved in the control of cell cycle arrest taking place during terminal cell differentiation and under stress conditions... - An avian model for studies of embryonic lymphangiogenesisJ Wilting
Anatomisches Institut der Albert Ludwigs Universität, Freiburg, Germany
Lymphology 33:81-94. 2000..Together with the early lymph sacs, the lymphangioblasts form the embryonic lymphatic system. Our studies demonstrate the importance of lymphangioblasts and lymphangiogenic growth factors in embryonic lymphangiogenesis... - The lymphatic endothelium of the avian wing is of somitic originJ Wilting
Anatomisches Institut II der Albert Ludwigs Universität Freiburg, Germany
Dev Dyn 217:271-8. 2000..This shows that not only the blood vascular cells but also the lymphatic endothelial cells of the avian wing are born in the paraxial/somitic mesoderm... - Embryonic lymphangiogenesisJ Wilting
Anatomisches Institut der Albert Ludwigs Universität Freiburg, Albertstrasse 17, D 79104 Freiburg, Germany
Cell Tissue Res 297:1-11. 1999..The greatest advantage resides in the fact that the lymphatics of the chorioallantoic membrane are easily accessible for experimental studies... - Genetic and epigenetic control of muscle development in vertebratesB Brand-Saberi
Anatomisches Institut II, Universitat Freiburg, Albertstrasse 17, D 79104 Freiburg, Germany
Cell Tissue Res 296:199-212. 1999..Future investigations will have to show how signalling molecules and their receptors interact in the process of fine-tuning muscle formation in the embryo... - Segmentation of the vertebrate bodyB Christ
Anatomisches Institut der Universitat Freiburg, Germany
Anat Embryol (Berl) 197:1-8. 1998..The expression of homologous genes indicates that the process of segmentation in vertebrates and invertebrates is homologous, derived by descent from a common ancestor... - Expression of the avian VEGF receptor homologues Quek1 and Quek2 in blood-vascular and lymphatic endothelial and non-endothelial cells during quail embryonic developmentJ Wilting
Anatomisches Institut II der Albert Ludwigs Universität, Albertstrasse 17, D 79104 Freiburg, Germany
Cell Tissue Res 288:207-23. 1997..Endothelial cells of lymph nodes and the periaortal lymphatic vessels are Quek2-positive in later stages. A few non-endothelial cells express Quek2... - Expression pattern of VEGFR-2 (Quek1) during quail developmentS Nimmagadda
Institute of Anatomy and Cell Biology II, University of Freiburg, Albertstrasse 17, 79104 Freiburg, Germany
Anat Embryol (Berl) 208:219-24. 2004..Our results confirm the angiogenic potential of the mesoderm and suggest that VEGFR-2 expressing cells represent multiple pools of mesodermal precursors of the hematopoietic and angiopoietic lineages... - Temporal and spatial protease nexin 1 expression during chick developmentM Rodriguez-Niedenführ
Institute of Anatomy II, University of Freiburg, PO Box 111, D 79001, Freiburg, Germany
Gene Expr Patterns 3:611-4. 2003..At these stages, expression was no longer observed in the Wolffian duct. At HH-stage 36, Pn-1 was expressed in the vertebral bodies, in the neural tube, and in the metanephros... - The role of Emx2 during scapula formationF Prols
Institute of Anatomy and Cell Biology II, University of Freiburg, D 79001 Freiburg, Germany
Dev Biol 275:315-24. 2004.... - Embryonic central nervous system angiogenesis does not involve blood-borne endothelial progenitorsH Kurz
Institute of Anatomy II, University of Freiburg, D 79104 Freiburg, Germany
J Comp Neurol 436:263-74. 2001.... - Arterial identity of endothelial cells is controlled by local cuesK Othman-Hassan
, Albertstrasse 17, 79104 Freiburg, Germany
Dev Biol 237:398-409. 2001..The studies show that the expression of the arterial marker ephrin-B2 is controlled by local cues in arterial vessels of older embryos. Physical forces or the media smooth muscle cells may be involved in this process... - Molecular and cellular analysis of embryonic avian tongue developmentR Huang
, Freiburg, Germany
Anat Embryol (Berl) 204:179-87. 2001..Data from this study suggests that the epithelium and mesenchyme express quite different genes during development. However BMP activity acts to inhibit growth in both tissues... 
Hepatocytes derived from adult stem cellsP Stock
First Department of Medicine, Martin Luther University of Halle Wittenberg, Halle, Germany
Transplant Proc 40:620-3. 2008..We characterized the functional properties of mesenchymal stem cells from various human tissues for their potential to differentiate into hepatocyte-like cells in vitro...- The homeobox transcription factor Prox1 is highly conserved in embryonic hepatoblasts and in adult and transformed hepatocytes, but is absent from bile duct epitheliumJ Dudas
Department of Gastroenterology and Endocrinology, Georg August University Gottingen, Robert Koch Strasse 40, Gottingen, Germany
Anat Embryol (Berl) 208:359-66. 2004..Its absence from bile duct epithelial cells suggests a function for the specification of hepatoblasts into hepatocytes. The genes controlled by Prox1 need to be studied in the future... - Expanding hepatocytes in vitro before cell transplantation: donor age-dependent proliferative capacity of cultured human hepatocytesJ Walldorf
First Dept of Medicine, Martin Luther University Halle Wittenberg, Halle Salle, Germany
Scand J Gastroenterol 39:584-93. 2004..The aim of this study was to identify differences in the proliferative capacity of cultured primary human hepatocytes related to the age of the liver donors... - Control of the temporal and spatial Uncx4.1 expression in the paraxial mesoderm of avian embryosJ Schrägle
Institute of Anatomy and Cell Biology II, Albert Ludwigs University, Albertstrasse 17, Freiburg, Germany
Anat Embryol (Berl) 208:323-32. 2004..1 expression in the caudal somite half. The neural tube is necessary for providing sufficient Uncx4.1 positive sclerotomal material to enable development of pedicles of the neural arches and transverse processes... - Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblastsM Rodriguez-Niedenführ
Anatomisches Institut der Albert Ludwigs Universität Freiburg, Germany
Anat Embryol (Berl) 204:399-406. 2001..In contrast, lymphangioblasts are present in the deep and superficial compartments of the early mesoderm, independently giving rise to the deep and superficial lymphatics... - Endogenous origin of the lymphatics in the avian chorioallantoic membraneM Papoutsi
, Albertstrasse 17, 79104 Freiburg, Germany
Dev Dyn 222:238-51. 2001..The latter can be identified with Prox1 antibodies and mRNA probes in the allantoic mesoderm of day 4 embryos (stage 21 HH). Prox1 is a specific marker of the lymphatic endothelium throughout CAM development... - The role of Pax-1 in axial skeleton developmentJ Wallin
Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, FRG
Development 120:1109-21. 1994..Our observations suggest that Pax-1 function is required for essential steps in ventral sclerotome differentiation, i.e. for the transition from the mesenchymal stage to the onset of chondrogenesis... - Patterning of fast and slow fibers within embryonic muscles is established independently of signals from the surrounding mesenchymeW Nikovits
Department of Medicine, Stanford University School of Medicine, Stanford, California 94305-5151, USA
Development 128:2537-44. 2001..These results demonstrate in vivo an intrinsic commitment to fiber-type on the part of the myoblast, independent of extrinsic signals it receives from the mesenchymal stroma in which it differentiates... - Inductive signals from the somatopleure mediated by bone morphogenetic proteins are essential for the formation of the sternal component of avian ribsH Sudo
Department of Molecular Embryology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan
Dev Biol 232:284-300. 2001..BMP4 alone, however, could not completely replace inductive signals from the somatopleure, suggesting the involvement of additional signals for rib formation... 
Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liverS Modaressi
Institut fur Biochemie und Molekulare Zellbiologie, Georg August Universitat, Gottingen, Germany
Biochem J 315:807-14. 1996..25 kb long, about 0.6 kb shorter than the mRNA of the cytosolic PCK. Primer extension experiments showed that the 5'-untranslated region of mitochondrial PCK mRNA was 134 nucleotides in length...- Hepatic progenitor cells from adult human livers for cell transplantationT S Weiss
Department of Surgery, Center for Liver Cell Research, University of Regensburg Hospital, Regensburg, Germany
Gut 57:1129-38. 2008..Histological studies implied that resident cells in adult liver can proliferate, have bipotential character and may be a suitable source for cell transplantation...