T Chakraborty


Affiliation: University of Giessen
Country: Germany


  1. Imirzalioglu C, Falgenhauer L, Schmiedel J, Waezsada S, Gwozdzinski K, Roschanski N, et al. Evaluation of a Loop-Mediated Isothermal Amplification-Based Assay for the Rapid Detection of Plasmid-Encoded Colistin Resistance Gene mcr-1 in Enterobacteriaceae Isolates. Antimicrob Agents Chemother. 2017;61: pubmed publisher
  2. Irrgang A, Hammerl J, Falgenhauer L, Guiral E, Schmoger S, Imirzalioglu C, et al. Diversity of CTX-M-1-producing E. coli from German food samples and genetic diversity of the blaCTX-M-1 region on IncI1 ST3 plasmids. Vet Microbiol. 2018;221:98-104 pubmed publisher
    ..Apart from conjugal transfer of IncI1 ST3 plasmids the transmission of the blaCTX-M-1 gene might be further promoted through mobilization due to its location within a recombination hot-spot of IncI1 plasmids. ..
  3. Mshana S, Fritzenwanker M, Falgenhauer L, Domann E, Hain T, Chakraborty T, et al. Molecular epidemiology and characterization of an outbreak causing Klebsiella pneumoniae clone carrying chromosomally located bla(CTX-M-15) at a German University-Hospital. BMC Microbiol. 2015;15:122 pubmed publisher
  4. Falgenhauer L, Ghosh H, Guerra B, Yao Y, Fritzenwanker M, Fischer J, et al. Comparative genome analysis of IncHI2 VIM-1 carbapenemase-encoding plasmids of Escherichia coli and Salmonella enterica isolated from a livestock farm in Germany. Vet Microbiol. 2017;200:114-117 pubmed publisher
  5. Fietz D, Markmann M, Lang D, Konrad L, Geyer J, Kliesch S, et al. Transfection of Sertoli cells with androgen receptor alters gene expression without androgen stimulation. BMC Mol Biol. 2015;16:23 pubmed publisher
    ..Studies using AR-transfected cells, subsequently stimulated, should consider alterations in AR-dependent gene expression as off-target effects of the AR transfection itself. ..
  6. Pati N, Doijad S, Schultze T, Mannala G, Yao Y, Jaiswal S, et al. Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection. Sci Rep. 2018;8:5392 pubmed publisher
    ..Further studies on the colonization and virulence potential of E. bugandensis and its association with septicemic infection is now warranted. ..
  7. Gwozdzinski K, Azarderakhsh S, Imirzalioglu C, Falgenhauer L, Chakraborty T. An Improved Medium for Colistin Susceptibility Testing. J Clin Microbiol. 2018;56: pubmed publisher
  8. request reprint
    Chakraborty T, Hain T, Domann E. Genome organization and the evolution of the virulence gene locus in Listeria species. Int J Med Microbiol. 2000;290:167-74 pubmed
    ..Thus, here we present an alternative view of the evolution of Listeria spp. and suggest that L. monocytogenes may be the primordial species of this genus. ..
  9. Zischka M, Künne C, Blom J, Wobser D, Sakιnç T, Schmidt Hohagen K, et al. Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40. BMC Genomics. 2015;16:175 pubmed publisher
    ..Molecular, genomic and phenotypic analysis of representative isolates of a major clone of E. faecalis MLST ST40 revealed new insights into the microbiology of a commensal bacterium which can turn into a conditional pathogen. ..

More Information


  1. Ghosh H, Doijad S, Bunk B, Falgenhauer L, Yao Y, Sproer C, et al. Detection of translocatable units in a blaCTX-M-15 extended-spectrum ?-lactamase-producing ST131 Escherichia coli isolate using a hybrid sequencing approach. Int J Antimicrob Agents. 2016;47:245-7 pubmed publisher
  2. Yao Y, Falgenhauer L, Kempf V, Hogardt M, Göttig S, Imirzalioglu C, et al. Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1. Genome Announc. 2017;5: pubmed publisher
    ..The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids indicating a large pool of transmissible antibiotic resistance genes. ..
  3. Pillich H, Puri M, Chakraborty T. ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor. Curr Top Microbiol Immunol. 2017;399:113-132 pubmed publisher
    ..These novel properties provide a new view of ActA and help explain its role as an essential virulence factor of L. monocytogenes. ..
  4. Yang G, Pillich H, White R, Czikora I, Pochic I, Yue Q, et al. Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells. Toxins (Basel). 2018;10: pubmed publisher
  5. Falgenhauer L, Imirzalioglu C, Ghosh H, Gwozdzinski K, Schmiedel J, Gentil K, et al. Circulation of clonal populations of fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST410 in humans and animals in Germany. Int J Antimicrob Agents. 2016;47:457-65 pubmed publisher
    ..These data provide strong evidence for the clonal dissemination of specific clades of CTX-M-15-producing E. coli ST410 in human and animal populations. ..
  6. Pillich H, Loose M, Zimmer K, Chakraborty T. Diverse roles of endoplasmic reticulum stress sensors in bacterial infection. Mol Cell Pediatr. 2016;3:9 pubmed publisher
    ..In this review, we will describe the mechanisms used by bacteria to activate the ER stress sensors and discuss their role during infection. ..
  7. Falgenhauer L, Waezsada S, Yao Y, Imirzalioglu C, Käsbohrer A, Roesler U, et al. Colistin resistance gene mcr-1 in extended-spectrum ?-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis. 2016;16:282-3 pubmed publisher
  8. Kuenne C, Billion A, Mraheil M, Strittmatter A, Daniel R, Goesmann A, et al. Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome. BMC Genomics. 2013;14:47 pubmed publisher
    ..These were comparatively analyzed in conjunction with publicly available data and assessed for pathogenicity in the Galleria mellonella insect model...
  9. Maurer J, Hupp S, Bischoff C, Foertsch C, Mitchell T, Chakraborty T, et al. Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins (Basel). 2017;9: pubmed publisher
    ..Thus, listeriolysin O demonstrated slower cell permeabilization and milder glial cell remodeling ability than did pneumolysin and lacked dendritic spine collapse capacity but exhibited equivalent dendritic pathology. ..
  10. Ghosh H, Bunk B, Doijad S, Schmiedel J, Falgenhauer L, Sproer C, et al. Complete Genome Sequence of blaCTX-M-27-Encoding Escherichia coli Strain H105 of Sequence Type 131 Lineage C1/H30R. Genome Announc. 2017;5: pubmed publisher
    ..Here, we present the complete genome sequence of the ST131 sublineage C1/H30R E. coli isolate harboring blaCTX-M-27 from Germany. ..
  11. Puri M, La Pietra L, Mraheil M, Lucas R, Chakraborty T, Pillich H. Listeriolysin O Regulates the Expression of Optineurin, an Autophagy Adaptor That Inhibits the Growth of Listeria monocytogenes. Toxins (Basel). 2017;9: pubmed publisher
    ..i>monocytogenes, either through induction or evasion, represents a key event in its intracellular life style and could lead to either cytosolic growth or persistence in intracellular vacuolar structures. ..