T Chakraborty

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. Zischka M, Künne C, Blom J, Wobser D, Sakιnç T, Schmidt Hohagen K, et al. Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40. BMC Genomics. 2015;16:175 pubmed publisher
    ..Molecular, genomic and phenotypic analysis of representative isolates of a major clone of E. faecalis MLST ST40 revealed new insights into the microbiology of a commensal bacterium which can turn into a conditional pathogen. ..
  2. Ghosh H, Doijad S, Bunk B, Falgenhauer L, Yao Y, Sproer C, et al. Detection of translocatable units in a blaCTX-M-15 extended-spectrum ?-lactamase-producing ST131 Escherichia coli isolate using a hybrid sequencing approach. Int J Antimicrob Agents. 2016;47:245-7 pubmed publisher
  3. Yao Y, Falgenhauer L, Kempf V, Hogardt M, Göttig S, Imirzalioglu C, et al. Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1. Genome Announc. 2017;5: pubmed publisher
    ..The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids indicating a large pool of transmissible antibiotic resistance genes. ..
  4. Falgenhauer L, Waezsada S, Yao Y, Imirzalioglu C, Käsbohrer A, Roesler U, et al. Colistin resistance gene mcr-1 in extended-spectrum ?-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis. 2016;16:282-3 pubmed publisher
  5. Pillich H, Loose M, Zimmer K, Chakraborty T. Diverse roles of endoplasmic reticulum stress sensors in bacterial infection. Mol Cell Pediatr. 2016;3:9 pubmed publisher
    ..In this review, we will describe the mechanisms used by bacteria to activate the ER stress sensors and discuss their role during infection. ..
  6. Falgenhauer L, Imirzalioglu C, Ghosh H, Gwozdzinski K, Schmiedel J, Gentil K, et al. Circulation of clonal populations of fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST410 in humans and animals in Germany. Int J Antimicrob Agents. 2016;47:457-65 pubmed publisher
    ..These data provide strong evidence for the clonal dissemination of specific clades of CTX-M-15-producing E. coli ST410 in human and animal populations. ..
  7. Pillich H, Puri M, Chakraborty T. ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor. Curr Top Microbiol Immunol. 2017;399:113-132 pubmed publisher
    ..These novel properties provide a new view of ActA and help explain its role as an essential virulence factor of L. monocytogenes. ..
  8. Yang G, Pillich H, White R, Czikora I, Pochic I, Yue Q, et al. Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells. Toxins (Basel). 2018;10: pubmed publisher
    ....
  9. Kuenne C, Billion A, Mraheil M, Strittmatter A, Daniel R, Goesmann A, et al. Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome. BMC Genomics. 2013;14:47 pubmed publisher
    ..These were comparatively analyzed in conjunction with publicly available data and assessed for pathogenicity in the Galleria mellonella insect model...
  10. Maurer J, Hupp S, Bischoff C, Foertsch C, Mitchell T, Chakraborty T, et al. Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins (Basel). 2017;9: pubmed publisher
    ..Thus, listeriolysin O demonstrated slower cell permeabilization and milder glial cell remodeling ability than did pneumolysin and lacked dendritic spine collapse capacity but exhibited equivalent dendritic pathology. ..

Locale

Detail Information

Publications12

  1. Zischka M, Künne C, Blom J, Wobser D, Sakιnç T, Schmidt Hohagen K, et al. Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40. BMC Genomics. 2015;16:175 pubmed publisher
    ..Molecular, genomic and phenotypic analysis of representative isolates of a major clone of E. faecalis MLST ST40 revealed new insights into the microbiology of a commensal bacterium which can turn into a conditional pathogen. ..
  2. Ghosh H, Doijad S, Bunk B, Falgenhauer L, Yao Y, Sproer C, et al. Detection of translocatable units in a blaCTX-M-15 extended-spectrum ?-lactamase-producing ST131 Escherichia coli isolate using a hybrid sequencing approach. Int J Antimicrob Agents. 2016;47:245-7 pubmed publisher
  3. Yao Y, Falgenhauer L, Kempf V, Hogardt M, Göttig S, Imirzalioglu C, et al. Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1. Genome Announc. 2017;5: pubmed publisher
    ..The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids indicating a large pool of transmissible antibiotic resistance genes. ..
  4. Falgenhauer L, Waezsada S, Yao Y, Imirzalioglu C, Käsbohrer A, Roesler U, et al. Colistin resistance gene mcr-1 in extended-spectrum ?-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis. 2016;16:282-3 pubmed publisher
  5. Pillich H, Loose M, Zimmer K, Chakraborty T. Diverse roles of endoplasmic reticulum stress sensors in bacterial infection. Mol Cell Pediatr. 2016;3:9 pubmed publisher
    ..In this review, we will describe the mechanisms used by bacteria to activate the ER stress sensors and discuss their role during infection. ..
  6. Falgenhauer L, Imirzalioglu C, Ghosh H, Gwozdzinski K, Schmiedel J, Gentil K, et al. Circulation of clonal populations of fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST410 in humans and animals in Germany. Int J Antimicrob Agents. 2016;47:457-65 pubmed publisher
    ..These data provide strong evidence for the clonal dissemination of specific clades of CTX-M-15-producing E. coli ST410 in human and animal populations. ..
  7. Pillich H, Puri M, Chakraborty T. ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor. Curr Top Microbiol Immunol. 2017;399:113-132 pubmed publisher
    ..These novel properties provide a new view of ActA and help explain its role as an essential virulence factor of L. monocytogenes. ..
  8. Yang G, Pillich H, White R, Czikora I, Pochic I, Yue Q, et al. Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells. Toxins (Basel). 2018;10: pubmed publisher
    ....
  9. Kuenne C, Billion A, Mraheil M, Strittmatter A, Daniel R, Goesmann A, et al. Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome. BMC Genomics. 2013;14:47 pubmed publisher
    ..These were comparatively analyzed in conjunction with publicly available data and assessed for pathogenicity in the Galleria mellonella insect model...
  10. Maurer J, Hupp S, Bischoff C, Foertsch C, Mitchell T, Chakraborty T, et al. Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins (Basel). 2017;9: pubmed publisher
    ..Thus, listeriolysin O demonstrated slower cell permeabilization and milder glial cell remodeling ability than did pneumolysin and lacked dendritic spine collapse capacity but exhibited equivalent dendritic pathology. ..
  11. Ghosh H, Bunk B, Doijad S, Schmiedel J, Falgenhauer L, Sproer C, et al. Complete Genome Sequence of blaCTX-M-27-Encoding Escherichia coli Strain H105 of Sequence Type 131 Lineage C1/H30R. Genome Announc. 2017;5: pubmed publisher
    ..Here, we present the complete genome sequence of the ST131 sublineage C1/H30R E. coli isolate harboring blaCTX-M-27 from Germany. ..
  12. Puri M, La Pietra L, Mraheil M, Lucas R, Chakraborty T, Pillich H. Listeriolysin O Regulates the Expression of Optineurin, an Autophagy Adaptor That Inhibits the Growth of Listeria monocytogenes. Toxins (Basel). 2017;9: pubmed publisher
    ..i>monocytogenes, either through induction or evasion, represents a key event in its intracellular life style and could lead to either cytosolic growth or persistence in intracellular vacuolar structures. ..