Research Topics
| Diego F CalvisiSummaryAffiliation: University of Greifswald Country: Germany Publications
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Detail Information
Publications
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinomaDiego F Calvisi
Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
Gastroenterology 140:1071-83. 2011..De novo lipogenesis is believed to be involved in oncogenesis. We investigated the role of aberrant lipid biosynthesis in the pathogenesis of human hepatocellular carcinoma (HCC)...
[De novo lipogenesis: role in hepatocellular carcinoma]D F Calvisi
Institut fur Pathologie, Ernst Moritz Arndt Universitätsmedizin, Friedrich Löffler Str 23e, 17489, Greifswald, Deutschland
Pathologe 32:174-80. 2011....
V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesisMatthias Evert
Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
Hepatology 55:1473-84. 2012..Thus, inhibition of AKT/mTOR and related metabolic changes might represent a novel preventive and therapeutic approach to effectively inhibit insulin-induced hepatocarcinogenesis...
Pathogenetic and Prognostic Significance of Inactivation of RASSF Proteins in Human Hepatocellular CarcinomaDiego F Calvisi
Institut fur Pathologie, Universitätsmedizin Greifswald, 17489 Greifswald, Germany
Mol Biol Int 2012:849874. 2012..Also, the present findings speak in favour of therapeutic strategies aimed at reexpressing RASSF1A, RASSF2, and RASSF5 genes and/or inactivating the RASSF cellular inhibitors for the treatment of human liver cancer...
NORE1A tumor suppressor candidate modulates p21CIP1 via p53Diego F Calvisi
Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
Cancer Res 69:4629-37. 2009..Thus, we define the molecular basis of NORE1A-mediated growth inhibition and implicate NORE1A as a potential component of the ill-defined connection between Ras and p53...
