Diego F Calvisi

Summary

Affiliation: University of Greifswald
Country: Germany

Publications

  1. pmc Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
    Diego F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Gastroenterology 140:1071-83. 2011
  2. doi request reprint [De novo lipogenesis: role in hepatocellular carcinoma]
    D F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitätsmedizin, Friedrich Löffler Str 23e, 17489, Greifswald, Deutschland
    Pathologe 32:174-80. 2011
  3. doi request reprint V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis
    Matthias Evert
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Hepatology 55:1473-84. 2012
  4. doi request reprint Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis
    Silvia Ribback
    Institut fur Pathologie, Universitätsmedizin Greifswald, Germany
    J Hepatol 58:1147-56. 2013
  5. pmc Pathogenetic and Prognostic Significance of Inactivation of RASSF Proteins in Human Hepatocellular Carcinoma
    Diego F Calvisi
    Institut fur Pathologie, Universitätsmedizin Greifswald, 17489 Greifswald, Germany
    Mol Biol Int 2012:849874. 2012
  6. doi request reprint NORE1A tumor suppressor candidate modulates p21CIP1 via p53
    Diego F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Cancer Res 69:4629-37. 2009

Collaborators

  • Frank Dombrowski
  • Andrea Thiele
  • Xin Chen
  • Silvia Ribback
  • Matthias Evert
  • Matthias Birth
  • Verena Sailer
  • Jenny Rausch
  • Antonio Cigliano
  • Michele Peters
  • Claus Dieter Heidecke
  • Sandra Mattu
  • Giulia Destefanis
  • Antje Zimmermann
  • Sara Ladu
  • Gioia Gasparetti
  • Katja Evert
  • Salvatore Delogu
  • Sara Thiel
  • Valentina De Murtas

Detail Information

Publications6

  1. pmc Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma
    Diego F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Gastroenterology 140:1071-83. 2011
    ..De novo lipogenesis is believed to be involved in oncogenesis. We investigated the role of aberrant lipid biosynthesis in the pathogenesis of human hepatocellular carcinoma (HCC)...
  2. doi request reprint [De novo lipogenesis: role in hepatocellular carcinoma]
    D F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitätsmedizin, Friedrich Löffler Str 23e, 17489, Greifswald, Deutschland
    Pathologe 32:174-80. 2011
    ....
  3. doi request reprint V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis
    Matthias Evert
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Hepatology 55:1473-84. 2012
    ..Noticeably, metabolic abnormalities and proliferation driven by insulin were effectively reverted using the dual PI3K/mTOR inhibitor, NVP-BEZ235, both in vitro and in vivo...
  4. doi request reprint Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis
    Silvia Ribback
    Institut fur Pathologie, Universitätsmedizin Greifswald, Germany
    J Hepatol 58:1147-56. 2013
    ..e., clear cell foci (CCF) of altered hepatocytes. CCF have also been described in the human liver, but molecular and metabolic alterations within these foci remain to be determined...
  5. pmc Pathogenetic and Prognostic Significance of Inactivation of RASSF Proteins in Human Hepatocellular Carcinoma
    Diego F Calvisi
    Institut fur Pathologie, Universitätsmedizin Greifswald, 17489 Greifswald, Germany
    Mol Biol Int 2012:849874. 2012
    ..Also, the present findings speak in favour of therapeutic strategies aimed at reexpressing RASSF1A, RASSF2, and RASSF5 genes and/or inactivating the RASSF cellular inhibitors for the treatment of human liver cancer...
  6. doi request reprint NORE1A tumor suppressor candidate modulates p21CIP1 via p53
    Diego F Calvisi
    Institut fur Pathologie, Ernst Moritz Arndt Universitat, Greifswald, Germany
    Cancer Res 69:4629-37. 2009
    ..Thus, we define the molecular basis of NORE1A-mediated growth inhibition and implicate NORE1A as a potential component of the ill-defined connection between Ras and p53...