I R Buschmann

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi request reprint GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function
    I R Buschmann
    Research Group for Experimental and Clinical Arteriogenesis at the Department of Cardiology and Angiology, Albert Ludwigs University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg im Breisgau, Germany
    Atherosclerosis 159:343-56. 2001
  2. ncbi request reprint Arteriogenesis - is this terminology necessary?
    Ivo Buschmann
    Albert Ludwigs University Freiburg Medical Clinic III, Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Breisacher Str 66, Germany
    Basic Res Cardiol 98:1-5. 2003
  3. ncbi request reprint Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor
    Ivo R Buschmann
    Albert Ludwigs University, Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Breisacher Strasse 66, Freiburg im Breisgau, Germany
    Circulation 108:610-5. 2003
  4. ncbi request reprint Granulocyte-macrophage colony-stimulating factor stimulates arteriogenesis in a pig model of peripheral artery disease using clinically applicable infusion pumps
    Sebastian Grundmann
    Department of Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany
    J Vasc Surg 43:1263-9. 2006
  5. ncbi request reprint Anti-tumor necrosis factor-{alpha} therapies attenuate adaptive arteriogenesis in the rabbit
    Sebastian Grundmann
    Department for Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany
    Am J Physiol Heart Circ Physiol 289:H1497-505. 2005
  6. ncbi request reprint Design of the START-trial: STimulation of ARTeriogenesis using subcutaneous application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind, placebo-controlled trial
    Niels van Royen
    Department of Cardiology, University of Amsterdam, The Netherlands
    Vasc Med 8:191-6. 2003
  7. ncbi request reprint Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation
    Niels van Royen
    Max Planck Institute for Physiological and Clinical Research, Department of Experimental Cardiology, Bad Nauheim, Germany
    FASEB J 16:432-4. 2002
  8. ncbi request reprint Divergent effects of GM-CSF and TGFbeta1 on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12: a potential role during arteriogenesis
    Marco M Jost
    Research Group for Experimental and Clinical Arteriogenesis at the Department for Internal Medicine III, Albert Ludwigs University Freiburg, Germany
    FASEB J 17:2281-3. 2003
  9. ncbi request reprint Influence of inflammatory cytokines on arteriogenesis
    Ivo Buschmann
    Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Albert Ludwigs University, Freiburg, Germany
    Microcirculation 10:371-9. 2003
  10. ncbi request reprint Noninvasive imaging of angiogenesis with a 99mTc-labeled peptide targeted at alphavbeta3 integrin after murine hindlimb ischemia
    Jing Hua
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8017, USA
    Circulation 111:3255-60. 2005

Collaborators

Detail Information

Publications12

  1. ncbi request reprint GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function
    I R Buschmann
    Research Group for Experimental and Clinical Arteriogenesis at the Department of Cardiology and Angiology, Albert Ludwigs University of Freiburg, Hugstetter Strasse 55, 79106, Freiburg im Breisgau, Germany
    Atherosclerosis 159:343-56. 2001
    ..In conclusion we have discovered a new function of the hemopoietic stem cell factor GM-CSF, which is also a powerful arteriogenic peptide that acts via prolongation of the life cycle of monocytes/macrophages...
  2. ncbi request reprint Arteriogenesis - is this terminology necessary?
    Ivo Buschmann
    Albert Ludwigs University Freiburg Medical Clinic III, Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Breisacher Str 66, Germany
    Basic Res Cardiol 98:1-5. 2003
    ..It is outlined that large conductance arteries rather than capillary networks are needed to compensate for perfusion deficits due to atherosclerotic stenosis or occlusion...
  3. ncbi request reprint Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor
    Ivo R Buschmann
    Albert Ludwigs University, Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Breisacher Strasse 66, Freiburg im Breisgau, Germany
    Circulation 108:610-5. 2003
    ..Thus far, angiogenesis studies have failed to demonstrate improvement of stroke outcome. Arteriogenesis differs from angiogenesis in that it substitutes arterial collaterals for the occluded artery...
  4. ncbi request reprint Granulocyte-macrophage colony-stimulating factor stimulates arteriogenesis in a pig model of peripheral artery disease using clinically applicable infusion pumps
    Sebastian Grundmann
    Department of Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany
    J Vasc Surg 43:1263-9. 2006
    ..We also aimed to compare continuous and intermittent infusion regimens and to validate experimental and clinically available measurements of collateral artery growth...
  5. ncbi request reprint Anti-tumor necrosis factor-{alpha} therapies attenuate adaptive arteriogenesis in the rabbit
    Sebastian Grundmann
    Department for Internal Medicine III Cardiology and Angiology, University Hospital Freiburg, Freiburg, Germany
    Am J Physiol Heart Circ Physiol 289:H1497-505. 2005
    ..This is the first report showing a negative influence of TNF-alpha inhibitors on collateral artery growth...
  6. ncbi request reprint Design of the START-trial: STimulation of ARTeriogenesis using subcutaneous application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind, placebo-controlled trial
    Niels van Royen
    Department of Cardiology, University of Amsterdam, The Netherlands
    Vasc Med 8:191-6. 2003
    ..Iliac flow reserve and conductance will be measured by magnetic resonance imaging...
  7. ncbi request reprint Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation
    Niels van Royen
    Max Planck Institute for Physiological and Clinical Research, Department of Experimental Cardiology, Bad Nauheim, Germany
    FASEB J 16:432-4. 2002
    ..10.11 +/- 0.04 x 10(5), P<0.05). TGF-beta1 had no direct pro-angiogenic effect on human umbilical vein endothelial cells in a spheroid model of angiogenesis and inhibited the angiogenic effects of vascular endothelial growth factor...
  8. ncbi request reprint Divergent effects of GM-CSF and TGFbeta1 on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12: a potential role during arteriogenesis
    Marco M Jost
    Research Group for Experimental and Clinical Arteriogenesis at the Department for Internal Medicine III, Albert Ludwigs University Freiburg, Germany
    FASEB J 17:2281-3. 2003
    ..Selective modulation of these mechanisms as well as cell-based therapies supplying arteriogenic factors in vivo point toward new strategies to influence collateral artery growth...
  9. ncbi request reprint Influence of inflammatory cytokines on arteriogenesis
    Ivo Buschmann
    Research Group for Experimental and Clinical Arteriogenesis, Department for Cardiology and Angiology, Albert Ludwigs University, Freiburg, Germany
    Microcirculation 10:371-9. 2003
    ..However, the results indicate that further studies are needed before proangiogenic and proarteriogenic therapies are ready for clinical application...
  10. ncbi request reprint Noninvasive imaging of angiogenesis with a 99mTc-labeled peptide targeted at alphavbeta3 integrin after murine hindlimb ischemia
    Jing Hua
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520 8017, USA
    Circulation 111:3255-60. 2005
    ..The alpha(v)beta3 integrin is activated in angiogenic vessels and represents a potential target for noninvasive imaging of angiogenesis...
  11. ncbi request reprint START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease
    Niels van Royen
    Department of Cardiology, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Circulation 112:1040-6. 2005
    ..Experimental models showed beneficial effects of GM-CSF on collateral artery growth in the peripheral circulation. Thus, in the present study, we evaluated the effects of GM-CSF in patients with peripheral artery disease...
  12. doi request reprint Neural guidance molecules, tip cells, and mechanical factors in vascular development
    Ferdinand Le Noble
    Department of Angiogenesis and Cardiovascular Pathology, Max Delbrueck Center for Molecular Medicine, Robert Roessle Strasse 10, 13125 Berlin, Germany
    Cardiovasc Res 78:232-41. 2008
    ..Here, studies on vascular development and adaptation in response to haemodynamic and molecular factors are integrated, with emphasis on arterial-venous network development and structural adaptation of vessels...