Katharina Buerger

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Clin Psychiatry 72:556-63. 2011
  2. doi request reprint Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, Munich 80336, Germany
    Biol Psychiatry 65:979-84. 2009
  3. doi request reprint Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
    Katharina Buerger
    Department of Psychiatry, Ludwig Maximilian University Munich, Munich, Germany
    Exp Gerontol 44:579-85. 2009
  4. ncbi request reprint CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Department of Psychiatry, Ludwig Maximilian University Munich, Germany
    Brain 129:3035-41. 2006
  5. ncbi request reprint Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Neurobiol Aging 27:10-5. 2006
  6. ncbi request reprint Phosphorylated tau predicts rate of cognitive decline in MCI subjects: a comparative CSF study
    K Buerger
    Memory Clinic, Alzheimer Memorial Center, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Neurology 65:1502-3. 2005
  7. ncbi request reprint Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Neurosci Lett 391:48-50. 2005
  8. ncbi request reprint Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study
    Harald Hampel
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Gen Psychiatry 61:95-102. 2004
  9. doi request reprint Effects of a 6-month cognitive intervention on brain metabolism in patients with amnestic MCI and mild Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 26:337-48. 2011
  10. doi request reprint Effects of a newly developed cognitive intervention in amnestic mild cognitive impairment and mild Alzheimer's disease: a pilot study
    Verena C Buschert
    Department of Psychiatry Ludwig Maximilians University, Munich, Germany
    J Alzheimers Dis 25:679-94. 2011

Detail Information

Publications29

  1. doi request reprint Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Clin Psychiatry 72:556-63. 2011
    ....
  2. doi request reprint Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, Munich 80336, Germany
    Biol Psychiatry 65:979-84. 2009
    ..We hypothesized that this set of blood-based (micro)circulation parameters is altered in AD...
  3. doi request reprint Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
    Katharina Buerger
    Department of Psychiatry, Ludwig Maximilian University Munich, Munich, Germany
    Exp Gerontol 44:579-85. 2009
    ..Data of the pilot European-ADNI (E-ADNI) biological marker programme of cerebrospinal fluid (CSF) and plasma candidate biomarkers are reported...
  4. ncbi request reprint CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Department of Psychiatry, Ludwig Maximilian University Munich, Germany
    Brain 129:3035-41. 2006
    ..There was a correlation between P-tau231P in CSF and brain homogenates. These findings indicate that CSF P-tau231P may serve as an in vivo surrogate biomarker of neurofibrillary pathology in Alzheimer's disease...
  5. ncbi request reprint Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Neurobiol Aging 27:10-5. 2006
    ..Our findings indicate a dissociation in the direction of change in CSF levels of t-tau and p-tau231 in CJD when compared to AD...
  6. ncbi request reprint Phosphorylated tau predicts rate of cognitive decline in MCI subjects: a comparative CSF study
    K Buerger
    Memory Clinic, Alzheimer Memorial Center, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Neurology 65:1502-3. 2005
  7. ncbi request reprint Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Neurosci Lett 391:48-50. 2005
    ..Our study indicates that the apoE epsilon4 carrier status should be considered when CSF P-tau(231P) is evaluated as biomarker candidate of AD in MCI subjects...
  8. ncbi request reprint Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study
    Harald Hampel
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Gen Psychiatry 61:95-102. 2004
    ..Different tau phosphoepitopes can be sensitively detected in cerebrospinal fluid (CSF)...
  9. doi request reprint Effects of a 6-month cognitive intervention on brain metabolism in patients with amnestic MCI and mild Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 26:337-48. 2011
    ..A six-month cognitive intervention imparted cognitive benefits in patients with aMCI, which were concurrent with an attenuated decline of glucose metabolism in cortical regions affected by neurodegenerative AD...
  10. doi request reprint Effects of a newly developed cognitive intervention in amnestic mild cognitive impairment and mild Alzheimer's disease: a pilot study
    Verena C Buschert
    Department of Psychiatry Ludwig Maximilians University, Munich, Germany
    J Alzheimers Dis 25:679-94. 2011
    ..In contrast, AD patients showed no significant benefit from intervention. The findings in this small sample support the use of the intervention in larger scales studies with an extended follow-up period to determine long-term effects...
  11. ncbi request reprint Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Am J Psychiatry 160:376-9. 2003
    ..The authors asked whether p-tau(231) levels improve the differential diagnosis between geriatric major depression and Alzheimer's disease...
  12. doi request reprint Antihypertensive therapy is associated with reduced rate of conversion to Alzheimer's disease in midregional proatrial natriuretic peptide stratified subjects with mild cognitive impairment
    Philine Schneider
    Alzheimer Memorial Center, Department of Psychiatry, Klinikum Grosshadern, Ludwig Maximilian University, Munich, Germany
    Biol Psychiatry 70:145-51. 2011
    ..Midregional proatrial natriuretic peptide (MR-proANP), an inactive surrogate molecule of the mature atrial natriuretic peptide, is related to circulatory function and hypertension...
  13. ncbi request reprint Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Arch Neurol 59:1267-72. 2002
    ....
  14. ncbi request reprint Advances in the development of biomarkers for Alzheimer's disease: from CSF total tau and Abeta(1-42) proteins to phosphorylated tau protein
    Harald Hampel
    Department of Psychiatry, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Ludwig Maximilian University, D 80336 Munich, Germany
    Brain Res Bull 61:243-53. 2003
    ....
  15. doi request reprint Effects of a 6-month cognitive intervention program on brain metabolism in amnestic mild cognitive impairment and mild Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 25:695-706. 2011
    ..A six-month cognitive intervention imparted cognitive benefits in patients with aMCI, which were concurrent with an attenuated decline of glucose metabolism in cortical regions affected by neurodegenerative AD...
  16. ncbi request reprint Levels of total tau and tau protein phosphorylated at threonine 181 in patients with incipient and manifest Alzheimer's disease
    Peter Schönknecht
    Department of Psychiatry, University of Heidelberg, Voss Strasse 4, D 69115, Heidelberg, Germany
    Neurosci Lett 339:172-4. 2003
    ..These findings suggest that total and phosphorylated tau protein may facilitate early detection and differential diagnosis of AD...
  17. ncbi request reprint Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    Jens Wiltfang
    Department of Psychiatry, University Erlangen Nurnberg, Germany
    Ann Neurol 54:263-7. 2003
    ..We conclude that the immunoblot shows disease-specific CSF Abeta peptide patterns in CJD and AD and suppose that measurement of the Abeta peptide pattern seems to be a promising diagnostic tool in the differential diagnosis of dementias...
  18. doi request reprint Perspectives for multimodal neurochemical and imaging biomarkers in Alzheimer's disease
    Stefan J Teipel
    Department of Psychiatry, University of Rostock, Rostock, Germany
    J Alzheimers Dis 33:S329-47. 2013
    ..Critical testing of these predictions will help us to modify or even falsify the currently hold assumptions on the pathogenesis of AD based on in vivo evidence in humans...
  19. doi request reprint Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls
    Markus J Schwarz
    Institute for Laboratory Medicine, University of Munich, Nussbaumstr 7, 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 263:345-52. 2013
    ..Our data therefore indicate an enhanced availability of 3-HK in the brain of AD patients, which may be related to the previously reported higher production of QUIN in AD brains...
  20. doi request reprint Biological marker candidates of Alzheimer's disease in blood, plasma, and serum
    Philine Schneider
    Department of Psychiatry, Ludwig Maximilian University, Alzheimer Memorial Center, Munich, Germany
    CNS Neurosci Ther 15:358-74. 2009
    ..The status and emerging perspectives on hypothesis and exploratory-based candidate biomarkers derived from blood, plasma, and serum are reviewed and discussed...
  21. ncbi request reprint Reliable manual segmentation of the frontal, parietal, temporal, and occipital lobes on magnetic resonance images of healthy subjects
    Arun L W Bokde
    Dementia and Neuro imaging Research Section, Alzheimer s Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, Station D2, 80336 Munich, Germany
    Brain Res Brain Res Protoc 14:135-45. 2005
    ..It is a challenge to reliably measure the lobar volumes from magnetic resonance imaging (MRI) data...
  22. ncbi request reprint Pharmacological treatment of Alzheimer's dementia: state of the art and current dilemmas
    Muamer Omerovic
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 9:69-75. 2008
    ..Furthermore, we discuss current difficulties regarding AD treatment by looking for explanations for a still unsatisfying rate of state-of-the-art treatment of AD-patients...
  23. ncbi request reprint Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia
    Stefan Lorenzl
    Department of Neurology and Neurosience, Weill Medical College of Cornell University, New York, USA
    Int Psychogeriatr 20:67-76. 2008
    ....
  24. doi request reprint Functional representation of olfactory impairment in early Alzheimer's disease
    Stefan Forster
    Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
    J Alzheimers Dis 22:581-91. 2010
    ....
  25. ncbi request reprint Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease
    Annica Johansson
    Department of Clinical Neuroscience, Unit of Neurochemistry, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Dement Geriatr Cogn Disord 20:367-74. 2005
    ..006, OR = 1.57, 95% CI 1.13-2.17). Our results provide further evidence for an involvement of cdc2 in the pathogenesis of AD...
  26. ncbi request reprint Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients
    Annika Olsson
    Institute of Clinical Neuroscience, Experimental Neuroscience Section, Goteborg University, Sahlgrenska University Hospital, Molndal, Sweden
    Exp Neurol 183:74-80. 2003
    ..Neither the levels of CSF-beta-sAPP nor CSF-Abeta(42) differed when comparing ApoE4 allele-positive with allele-negative individuals...
  27. ncbi request reprint Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease
    Richard Dodel
    Department of Neurology, Philipps University Marburg, Germany
    Ann Neurol 52:253-6. 2002
    ..This study provides evidence that intravenous immunoglobulin or purified Abeta antibodies may modify Abeta and Abeta(1-42) levels, suggesting potential utility as a therapy for Alzheimer disease...
  28. ncbi request reprint No correlation between CSF tau protein phosphorylated at threonine 181 with neocortical neurofibrillary pathology in Alzheimer's disease
    Katharina Buerger
    Brain 130:e82. 2007
  29. ncbi request reprint Procalcitonin is elevated in the cerebrospinal fluid of patients with dementia and acute neuroinflammation
    Andrea Ernst
    SphingoTec GmbH, Tulpenweg 6, D 16556 Borgsdorf, Germany
    J Neuroimmunol 189:169-74. 2007
    ..Our results indicate a central production of PCT and suggest PCT as a valuable marker candidate for the monitoring of dementia and acute neuroinflammation...