Lygia T Budnik

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. pmc Circulating mitochondrial DNA as biomarker linking environmental chemical exposure to early preclinical lesions elevation of mtDNA in human serum after exposure to carcinogenic halo-alkane-based pesticides
    Lygia T Budnik
    Institute for Occupational and Maritime Medicine, Department of Occupational Health, School of Medicine, University of Hamburg, Hamburg, Germany
    PLoS ONE 8:e64413. 2013
  2. pmc Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks
    Lygia T Budnik
    Division of Occupational Toxicology and Immunology, Institute for Occupational and Maritime Medicine ZfAM, Medical Faculty, University of Hamburg, University Medical Center, Hamburg, Germany
    Environ Health 11:5. 2012
  3. ncbi request reprint Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor
    Lygia T Budnik
    Institute for Hormone and Fertility Research, Anatomy I, University Hospital Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
    J Lipid Res 46:930-41. 2005
  4. pmc Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies
    Lygia T Budnik
    Institute for Occupational Medicine and Maritime Medicine ZfAM, University Medical Center, Hamburg Eppendorf, Hamburg, Germany
    J Occup Med Toxicol 6:9. 2011
  5. doi request reprint Halogenated hydrocarbon pesticides and other volatile organic contaminants provide analytical challenges in global trading
    Lygia T Budnik
    Department of Occupational Toxicology and Molecular Biology, Institute for Occupational and Maritime Medicine ZfAM, Marckmannstrasse 129b, Hamburg, Germany
    J Environ Monit 12:936-42. 2010
  6. ncbi request reprint Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway?
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, D 20251 Hamburg, Germany
    Mol Endocrinol 17:1593-606. 2003
  7. doi request reprint Surprises perilous: toxic health hazards for employees unloading fumigated shipping containers
    Alexandra M Preisser
    Department of Clinical Occupational Medicine, Institute for Occupational and Maritime Medicine ZfAM, University Medical Center Hamburg Eppendorf, Seewartenstrasse 10, D 20459 Hamburg, Germany
    Sci Total Environ 409:3106-13. 2011
  8. ncbi request reprint Lysophosphatidic acid-induced nuclear localization of protein kinase C delta in bovine theca cells stimulated with luteinizing hormone
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, D 22529 Hamburg, Germany
    Biol Reprod 67:935-44. 2002
  9. pmc The assessment of environmental and occupational exposure to hazardous substances by biomonitoring
    Lygia T Budnik
    Ordinariat für Arbeitsmedizin des Universitätsklinikums Hamburg Eppendorf, Zentralinstitut für Arbeitsmedizin und Maritime Medizin, Hamburg, Germany
    Dtsch Arztebl Int 106:91-7. 2009
  10. pmc Lysophosphatidic acid, LPA: a bad boy becomes good
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, Centrum for Innovative Medicine, Falkenried 88, D 20251 Hamburg, Germany
    Reprod Biol Endocrinol 1:37. 2003

Collaborators

Detail Information

Publications12

  1. pmc Circulating mitochondrial DNA as biomarker linking environmental chemical exposure to early preclinical lesions elevation of mtDNA in human serum after exposure to carcinogenic halo-alkane-based pesticides
    Lygia T Budnik
    Institute for Occupational and Maritime Medicine, Department of Occupational Health, School of Medicine, University of Hamburg, Hamburg, Germany
    PLoS ONE 8:e64413. 2013
    ..Our findings indicate that mitochondrial DNA has a potential to serve as a biomarker recognizing vulnerable risk groups after exposure to toxic/carcinogenic chemicals...
  2. pmc Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks
    Lygia T Budnik
    Division of Occupational Toxicology and Immunology, Institute for Occupational and Maritime Medicine ZfAM, Medical Faculty, University of Hamburg, University Medical Center, Hamburg, Germany
    Environ Health 11:5. 2012
    ..g. in globalized transport and storage). The withdrawal of methyl bromide because of its environmental risk could fortuitously help in the containment of its human toxicity...
  3. ncbi request reprint Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor
    Lygia T Budnik
    Institute for Hormone and Fertility Research, Anatomy I, University Hospital Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
    J Lipid Res 46:930-41. 2005
    ..Surprisingly, however, exogenous S1P inhibits agonist-stimulated progesterone in both cell types by inhibiting cyclic AMP accumulation, suggesting different mechanisms of action...
  4. pmc Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies
    Lygia T Budnik
    Institute for Occupational Medicine and Maritime Medicine ZfAM, University Medical Center, Hamburg Eppendorf, Hamburg, Germany
    J Occup Med Toxicol 6:9. 2011
    ..abstract:..
  5. doi request reprint Halogenated hydrocarbon pesticides and other volatile organic contaminants provide analytical challenges in global trading
    Lygia T Budnik
    Department of Occupational Toxicology and Molecular Biology, Institute for Occupational and Maritime Medicine ZfAM, Marckmannstrasse 129b, Hamburg, Germany
    J Environ Monit 12:936-42. 2010
    ....
  6. ncbi request reprint Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway?
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, D 20251 Hamburg, Germany
    Mol Endocrinol 17:1593-606. 2003
    ..The findings indicate that LPA transiently stimulates MAPK ERK in LPA1/edg2-expressing theca cells and suggest an alternative mechanism regulating the activation of ERK that differs from the canonical EGF-Ras-MAPK kinase pathway...
  7. doi request reprint Surprises perilous: toxic health hazards for employees unloading fumigated shipping containers
    Alexandra M Preisser
    Department of Clinical Occupational Medicine, Institute for Occupational and Maritime Medicine ZfAM, University Medical Center Hamburg Eppendorf, Seewartenstrasse 10, D 20459 Hamburg, Germany
    Sci Total Environ 409:3106-13. 2011
    ..These findings also emphasize the necessity for international standards on permitted fumigants, appropriate labeling in the shipping documents and handling of fumigated containers...
  8. ncbi request reprint Lysophosphatidic acid-induced nuclear localization of protein kinase C delta in bovine theca cells stimulated with luteinizing hormone
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, D 22529 Hamburg, Germany
    Biol Reprod 67:935-44. 2002
    ..Because PKCdelta supports a luteotropic function in rodent models, a similar role in the bovine ovary is also likely...
  9. pmc The assessment of environmental and occupational exposure to hazardous substances by biomonitoring
    Lygia T Budnik
    Ordinariat für Arbeitsmedizin des Universitätsklinikums Hamburg Eppendorf, Zentralinstitut für Arbeitsmedizin und Maritime Medizin, Hamburg, Germany
    Dtsch Arztebl Int 106:91-7. 2009
    ....
  10. pmc Lysophosphatidic acid, LPA: a bad boy becomes good
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, Centrum for Innovative Medicine, Falkenried 88, D 20251 Hamburg, Germany
    Reprod Biol Endocrinol 1:37. 2003
  11. ncbi request reprint Lysophosphatidic acid and its role in reproduction
    Lygia T Budnik
    Institute for Hormone and Fertility Research, University of Hamburg, Grandweg 64, D 22529 Hamburg, Germany
    Biol Reprod 66:859-65. 2002
    ....
  12. ncbi request reprint Homologous and lysophosphatidic acid-induced desensitization of the atrial natriuretic peptide receptor, guanylyl cyclase-A, in MA-10 leydig cells
    Dieter Muller
    Institute of Anatomy and Cell Biology, Justus Liebig University, Giessen, Germany
    Endocrinology 147:2974-85. 2006
    ..The morphoregulatory activities exerted by LPA suggest a crucial role for Leydig cell physiology...