Research Topics
| N H BrockmeyerSummaryAffiliation: University of Essen Country: Germany Publications
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Detail Information
Publications
Effect of zidovudine therapy in patients with HIV infection on endogenous interferon plasma levels and the hepatic cytochrome P450 enzyme systemN H Brockmeyer
Klinik fur Dermatologie, Venerologie und Allergologie, Universitat Essen, Deutschland, Germany
Chemotherapy 44:174-80. 1998..9 +/- 2.6 U/ml, 1.9 +/- 1.3 U/ml after administration of ZDV), a decrease in antipyrine half-life, an elevation of the antipyrine clearance (49.8 +/- 15.7 ml/min, 57.3 +/- 13.7 ml/min) and an elevation of the clearances to metabolite...
Pharmacokinetic interaction of fluconazole and zidovudine in HIV-positive patientsN H Brockmeyer
Universitat Essen, Klinik fur Dermatologie, Venerologie und Allergologie, Hufelandstr 55, Essen D 45147, Germany
Eur J Med Res 2:377-83. 1997..High doses of fluconazole can inhibit the plasma elimination of both antipyrine and zidovudine, but the extent of this inhibitory effect is so small that no clinically relevant accumulation is to be expected...
