- [Current developments in xenon research. Importance for anesthesia and intensive care medicine]A Brücken
Klinik fur Anasthesiologie, Universitätsklinikum der RWTH Aachen, Pauwelsstr 30, 52074 Aachen
Anaesthesist 59:883-95. 2010..As the high cost of xenon will probably preclude its wider use as a routine anesthetic, data from extensive tests in large numbers of high risk patients is needed to confirm its possible superiority in this setting...
- Dose dependent neuroprotection of the noble gas argon after cardiac arrest in rats is not mediated by KATP-Channel openingAnne Brücken
Department of Anaesthesiology, University Hospital RWTH Aachen, Aachen, Germany Electronic address
Resuscitation 85:826-32. 2014..In a rodent model, we investigated if the neuroprotective effects of argon are dose dependent and mediated by adenosine triphosphate dependent potassium (KATP) channels...
- Reducing the duration of 100% oxygen ventilation in the early reperfusion period after cardiopulmonary resuscitation decreases striatal brain damageAnne Brücken
Department of Anesthesiology, University Hospital RWTH Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
Resuscitation 81:1698-703. 2010..We retrospectively analyzed data from a porcine CA model and hypothesized that prolonged hyperoxic reperfusion would be associated with increased neurohistopathological damage and impaired neurological recovery...
- Combining xenon and mild therapeutic hypothermia preserves neurological function after prolonged cardiac arrest in pigsMichael Fries
Department of Surgical Intensive Care, University Hospital RWTH Aachen, Aachen, Germany
Crit Care Med 40:1297-303. 2012..Administering xenon may confer an additional neuroprotective effect after successful cardiopulmonary resuscitation due to its ability to stabilize cellular calcium homeostasis via N-methyl-D-aspartate-receptor antagonism...