S Braun

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease
    S Braun
    I Frauenklinik, Klinikum Innenstadt, Ludwig Maximilians Universitat, Munich, Germany
    Int J Cancer 84:1-5. 1999
  2. ncbi request reprint Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients
    S Braun
    I Frauenklinik der Ludwig Maximilians Universität, Munich, Germany
    J Clin Oncol 18:80-6. 2000
  3. ncbi request reprint Monoclonal antibody therapy with edrecolomab in breast cancer patients: monitoring of elimination of disseminated cytokeratin-positive tumor cells in bone marrow
    S Braun
    I Frauenklinik, Klinikum Innenstsdt, Ludwig Maximilians Universitat, Munich, Germany
    Clin Cancer Res 5:3999-4004. 1999
  4. ncbi request reprint Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer
    S Braun
    I Frauenklinik, Klinikum Innenstadt, Ludwig Maximilians University, Munich, Germany
    N Engl J Med 342:525-33. 2000
  5. ncbi request reprint Isolated tumor cells in the bone marrow (ITC-BM) of breast cancer patients before and after anthracyclin based therapy: influenced by the HER2- and Topoisomerase IIalpha-status of the primary tumor?
    C Schindlbeck
    I Frauenklinik, Klinikum der Ludwig Maximilians Universität, Maistrasse 11, 80337 Munich, Germany
    J Cancer Res Clin Oncol 131:539-46. 2005
  6. ncbi request reprint Occult tumor cells in bone marrow of patients with locoregionally restricted ovarian cancer predict early distant metastatic relapse
    S Braun
    I Frauenklinik and Institute of Immunology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    J Clin Oncol 19:368-75. 2001
  7. ncbi request reprint The fate and prognostic value of occult metastatic cells in the bone marrow of patients with breast carcinoma between primary treatment and recurrence
    W Janni
    I Frauenklinik, Klinikum der Ludwig Maximilians Universtitaet, Muenchen, Germany
    Cancer 92:46-53. 2001
  8. ncbi request reprint Comparative analysis of micrometastasis to the bone marrow and lymph nodes of node-negative breast cancer patients receiving no adjuvant therapy
    S Braun
    I Frauenklinik and Department of Gynecological Pathology, Klinikum Innenstadt, Ludwig Maximilians University, Munchen, Gemany
    J Clin Oncol 19:1468-75. 2001
  9. ncbi request reprint Radiotherapy of the chest wall following mastectomy for early-stage breast cancer: impact on local recurrence and overall survival
    W Janni
    I Frauenklinik, Ludwig Maximilians Universtitaet, Maistr 11, D 80337, Muenchen, Germany
    Int J Radiat Oncol Biol Phys 48:967-75. 2000
  10. doi request reprint Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy
    D Sibbing
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:1685-93. 2010

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease
    S Braun
    I Frauenklinik, Klinikum Innenstadt, Ludwig Maximilians Universitat, Munich, Germany
    Int J Cancer 84:1-5. 1999
    ..Thus, defining target antigens expressed by the actual target cells emerges as a crucial first step in selecting appropriate therapeutic targets...
  2. ncbi request reprint Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients
    S Braun
    I Frauenklinik der Ludwig Maximilians Universität, Munich, Germany
    J Clin Oncol 18:80-6. 2000
    ..This study was designed to evaluate whether monitoring of micrometastases in bone marrow can predict the response to systemic chemotherapy in breast cancer...
  3. ncbi request reprint Monoclonal antibody therapy with edrecolomab in breast cancer patients: monitoring of elimination of disseminated cytokeratin-positive tumor cells in bone marrow
    S Braun
    I Frauenklinik, Klinikum Innenstsdt, Ludwig Maximilians Universitat, Munich, Germany
    Clin Cancer Res 5:3999-4004. 1999
    ..Selection of EpCAM-/ CK+ tumor clones showed that further antibodies directed against tumor-associated antigens are warranted to improve the efficacy of monospecific approaches...
  4. ncbi request reprint Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer
    S Braun
    I Frauenklinik, Klinikum Innenstadt, Ludwig Maximilians University, Munich, Germany
    N Engl J Med 342:525-33. 2000
    ..Cytokeratins are specific markers of epithelial cancer cells in bone marrow. We assessed the influence of cytokeratin-positive micrometastases in the bone marrow on the prognosis of women with breast cancer...
  5. ncbi request reprint Isolated tumor cells in the bone marrow (ITC-BM) of breast cancer patients before and after anthracyclin based therapy: influenced by the HER2- and Topoisomerase IIalpha-status of the primary tumor?
    C Schindlbeck
    I Frauenklinik, Klinikum der Ludwig Maximilians Universität, Maistrasse 11, 80337 Munich, Germany
    J Cancer Res Clin Oncol 131:539-46. 2005
    ....
  6. ncbi request reprint Occult tumor cells in bone marrow of patients with locoregionally restricted ovarian cancer predict early distant metastatic relapse
    S Braun
    I Frauenklinik and Institute of Immunology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    J Clin Oncol 19:368-75. 2001
    ..Consequently, we investigated the incidence of early hematogenous dissemination and its association with distant disease-free and overall survival...
  7. ncbi request reprint The fate and prognostic value of occult metastatic cells in the bone marrow of patients with breast carcinoma between primary treatment and recurrence
    W Janni
    I Frauenklinik, Klinikum der Ludwig Maximilians Universtitaet, Muenchen, Germany
    Cancer 92:46-53. 2001
    ....
  8. ncbi request reprint Comparative analysis of micrometastasis to the bone marrow and lymph nodes of node-negative breast cancer patients receiving no adjuvant therapy
    S Braun
    I Frauenklinik and Department of Gynecological Pathology, Klinikum Innenstadt, Ludwig Maximilians University, Munchen, Gemany
    J Clin Oncol 19:1468-75. 2001
    ..In the present study we analyzed whether a correlation exists between microscopic tumor cell spread to bone marrow and to lymph nodes and attempted to determine which route is clinically more important...
  9. ncbi request reprint Radiotherapy of the chest wall following mastectomy for early-stage breast cancer: impact on local recurrence and overall survival
    W Janni
    I Frauenklinik, Ludwig Maximilians Universtitaet, Maistr 11, D 80337, Muenchen, Germany
    Int J Radiat Oncol Biol Phys 48:967-75. 2000
    ..This study was designed to clarify whether or not routine radiotherapy of the chest wall following mastectomy reduces the risk of local recurrence and if it influences the overall survival rate...
  10. doi request reprint Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy
    D Sibbing
    Deutsches Herzzentrum München and 1 Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:1685-93. 2010
    ..Currently, the isolated and interactive impacts of both variants on the antiplatelet effects of chronic clopidogrel therapy are unknown...
  11. doi request reprint Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement
    D Sibbing
    Deutsches Herzzentrum München and I Medizinische Klinik, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Thromb Haemost 8:250-6. 2010
    ..In patients undergoing percutaneous coronary intervention (PCI), a link between bleeding and excess mortality has been demonstrated. A potential association of platelet response to clopidogrel and bleeding has not been well established yet...
  12. doi request reprint Pre-procedural C-reactive protein levels and clinical outcomes after percutaneous coronary interventions with and without abciximab: pooled analysis of four ISAR trials
    R Iijima
    Deutsches Herzzentrum, Technische Universitat, Munich, Germany
    Heart 95:107-12. 2009
    ....
  13. ncbi request reprint Clinical relevance of occult metastatic cells in the bone marrow of patients with different stages of breast cancer
    W Janni
    I Frauenklinik, Klinikum Innenstadt, Ludwig Maximilians Universitat, Munich, Germany
    Clin Breast Cancer 1:217-25. 2000
    ..The present review also focuses on state of the art, reliable detection methods of occult metastatic cells in the bone marrow of breast cancer patients and on the prognostic relevance of these cells at different stages of the disease...
  14. doi request reprint Antiplatelet efficacy of prasugrel in patients with high on-clopidogrel treatment platelet reactivity and a history of coronary stenting
    Isabell Bernlochner
    Deutsches Herzzentrum, Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Thromb Haemost 109:517-24. 2013
    ..However, prasugrel response variability was detected, being more pronounced on prasugrel MD vs. LD treatment. The clinical impact of these findings warrants further investigation...
  15. ncbi request reprint Comparative analysis between the HER2 status in primary breast cancer tissue and the detection of isolated tumor cells in the bone marrow
    C Schindlbeck
    I Frauenklinik, Klinikum Ludwig Maximilians University, Munich, Germany
    Breast Cancer Res Treat 87:65-74. 2004
    ..The direct identification of HER2 on ITC-BM is the aim of ongoing research, potentially synergizing the prognostic relevance of ITC-BM and the predictive value of the HER2 status...
  16. pmc Recent advances in technologies for the detection of occult metastatic cells in bone marrow of breast cancer patients
    S Braun
    Department of Obstetrics and Gynecology, Clinical Research Unit, Technical University, Munich, Germany
    Breast Cancer Res 3:285-8. 2001
    ..Standardized and robust methodology is a prerequisite for clinical application of these techniques, however...
  17. ncbi request reprint [Incidence and prognostic significance of disseminated tumor cells in patients with cervical cancer]
    B Rack
    I Frauenklinik, Klinikum Innenstadt der Ludwig Maximilians Universität, Maistrasse 11, D 80337 München, Deutschland
    Acta Med Austriaca Suppl 59:36-41. 2002
    ..In view of the data on disseminated tumor cells in other tumor entities, these early results might offer new options for refined tumor staging and improved treatment options...
  18. ncbi request reprint [Tumor biology of primary breast cancer and minimal residual disease]
    C Schindlbeck
    I Frauenklinik, Klinikum der Ludwig Maximilians Universität, Maistrasse 11, D 80337 München, Deutschland
    Acta Med Austriaca Suppl 59:27-31. 2002
    ..Preliminary results on multi colour stained samples indicate that a selection of certain biological factors takes place during tumor cell dissemination...
  19. ncbi request reprint Low preoperative antithrombin activity causes reduced response to heparin in adult but not in infant cardiac-surgical patients
    W Dietrich
    Department of Anesthesiology, German Heart Center, Munich, Germany
    Anesth Analg 92:66-71. 2001
    ..Measurement of preoperative AT activity identifies patients at risk of inadequate anticoagulation during CPB...
  20. doi request reprint Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes
    G Ndrepepa
    Division of Cardiology, German Heart Center in Munich, Munich, Germany
    Eur J Clin Invest 38:90-6. 2008
    ..The aim of the study was to compare MPO level across the entire spectrum of CAD, to assess the accuracy of MPO in predicting acute coronary syndromes and to define independent correlates of MPO level...
  21. ncbi request reprint Glycoprotein Ia C807T polymorphism and risk of restenosis following coronary stenting
    N von Beckerath
    Deutsches Herzzentrum München and 1 Medizinische Klinik rechts der Isar, Technische Universitat Munchen, Lazarettstr 36, 80636, Munich, Germany
    Atherosclerosis 156:463-8. 2001
    ..6% for CC, 21.7% for CT and 21.2% for TT patients (P=0.98). Thus, carriage of the GP Ia T807 allele is not associated with an increased risk of restenosis or unfavorable late outcome following coronary artery stenting...
  22. ncbi request reprint Clinical significance of occult metastatic cells in bone marrow of breast cancer patients
    S Braun
    Frauenklinik und Poliklinik, , Klinikum rechts der Isar, , Germany
    Oncologist 6:125-32. 2001
    ..The present review summarizes the current data on the clinical significance of occult metastatic breast cancer cells in bone marrow...
  23. ncbi request reprint Characterization of disseminated tumor cells
    S B Hosch
    Chirurgische Klinik, , Hamburg, Germany
    Semin Surg Oncol 20:265-71. 2001
    ..This review summarizes the current knowledge on the biological characteristics of micrometastatic cancer cells in bone marrow and lymph nodes of cancer patients...
  24. ncbi request reprint [Technical aspects of immunocytochemical detection of disseminated tumor cells in bone marrow]
    S Braun
    Universitatsklinik fur Frauenheilkunde, Anichstrasse 35, A 6020 Innsbruck
    Acta Med Austriaca Suppl 59:14-7. 2002
    ..This review summarises the currently available data on techniques that can be used to detect metastatic breast cancer cells in bone marrow and values their opportunities and limitations...
  25. ncbi request reprint Nuclear localization and DNA binding of ecdysone receptor and ultraspiracle
    M V Cronauer
    Institute of General Zoology and Endocrinology, University of Ulm, Ulm, Germany
    Arch Insect Biochem Physiol 65:125-33. 2007
    ..The results indicate that EcR and Usp can enter the nucleus independently, but cotransport of both receptors mediated by dimerization via the ligand binding domains is possible even in the absence of hormone...
  26. ncbi request reprint [Acetone treatment of lymph node preparations in staging colorectal specimens]
    D Richter
    Institut für Pathologie und Zytologie, Dr Horst Schmidt Kliniken GmbH, Ludwig Erhardt Strasse 100, 65199, Wiesbaden
    Pathologe 28:269-72. 2007
    ..Lymph node preparation after acetone treatment is an easy, low cost method resulting in a much larger number of lymph nodes for more accurate staging...
  27. ncbi request reprint [Traveler's thrombosis]
    S Braun
    Klinik und Poliklinik für Hautkrankheiten, Ernst Moritz Arndt Universitat, Greifswald
    Hautarzt 54:518-23. 2003
    ..Therefore, prophylaxis of thromboembolic events during long distance journeys can only be considered good advice (with the exception of leg exercise) instead of an evidence-based recommendation...
  28. ncbi request reprint [Importance of occult metastatic cells in the treatment of patients with breast and gastrointestinal cancers]
    S Braun
    Universitätsklinikum für Frauenheilkunde, Leopold Franzens Universitat, Innsbruck, Osterreich
    Acta Med Austriaca Suppl 59:18-26. 2002
    ..This review summarizes the currently available data on the importance of disseminated tumor cells for the treatment of patients with breast or gastrointestinal cancer...
  29. ncbi request reprint [About type and incidence of heart disease in psittacines kept in captivity in Germany]
    S Braun
    Klinik für Kleintiere, Veterinärmedizinische Fakultät der Universität Leipzig
    Dtsch Tierarztl Wochenschr 109:255-60. 2002
    ..This study allocates that especially noninfectious heart disease is of markedly importance in psittacines and that their evidence is much higher than it might be suspected on the basis of publications...
  30. ncbi request reprint [Breast carcinoma. Biological principles, classification and prognostic factors]
    S Braun
    Frauenklinik and Poliklinik, Technischen Universitat Munchen, Klinikum rechts der Isar Ismaninger Strasse 22, 81675 Munchen
    Internist (Berl) 43:329-30, 333-9. 2002
  31. ncbi request reprint Immunodiagnosis and immunotherapy of isolated tumor cells disseminated to bone marrow of patients with colorectal cancer
    S Braun
    I. Universitats-Frauenklinik, Ludwig-Maximilians-Universitat, Munchen, Germany
    Tumori 81:78-83. 1995
    ..The present article reviews the current state of immunologic strategies used to detect, characterize, and treat minimal residual colon cancer...