Ralf J Braun

Summary

Affiliation: University of Bayreuth
Location: , Germany

Publications

  1. ncbi Improved proteome analysis of Saccharomyces cerevisiae mitochondria by free-flow electrophoresis
    Hans Zischka
    GSF Research Centre for Environment and Health, Institute of Human Genetics, Oberschleissheim, Germany
    Proteomics 3:906-16. 2003
  2. doi Mitochondrial dynamics in yeast cell death and aging
    Ralf J Braun
    Institut fur Zellbiologie, Universitat Bayreuth, 95440 Bayreuth, Germany
    Biochem Soc Trans 39:1520-6. 2011
  3. pmc A new Canterbury tale: the eighth International Meeting on Yeast Apoptosis in Canterbury, UK, 2-6 May 2011
    D Carmona-Gutierrez
    1 Institute of Molecular Biosciences, University of Graz, Graz, Austria 2 Institute of Biochemistry, Technical University of Graz, Graz, Austria
    Cell Death Differ 18:1948-9. 2011
  4. pmc Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast
    Ralf J Braun
    Institute of Molecular Biosciences, University of Graz, Graz, Austria
    J Biol Chem 286:19958-72. 2011
  5. doi Nervous yeast: modeling neurotoxic cell death
    Ralf J Braun
    Institute of Molecular Biosciences, Department of Microbiology, Karl Franzens University of Graz, Graz, Austria
    Trends Biochem Sci 35:135-44. 2010
  6. doi 16-BAC/SDS-PAGE analysis of membrane proteins of yeast mitochondria purified by free flow electrophoresis
    Ralf J Braun
    GSF National Research Centre for Environment and Health, Institute of Human Genetics, Munich, Germany
    Methods Mol Biol 528:83-107. 2009
  7. doi Purification of Saccharomyces cerevisiae mitochondria by zone electrophoresis in a free flow device
    Hans Zischka
    GSF National Research Center for Environment and Health, Institute of Toxicology, Munich Neuherberg, Germany
    Methods Mol Biol 432:51-64. 2008
  8. doi Mechanisms of Cdc48/VCP-mediated cell death: from yeast apoptosis to human disease
    Ralf J Braun
    Institute of Human Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Munich Neuherberg, Germany
    Biochim Biophys Acta 1783:1418-35. 2008
  9. ncbi Two-dimensional electrophoresis of membrane proteins
    Ralf J Braun
    GSF National Research Center for Environment and Health, Institute of Human Genetics, Ingolstaedter Landstrasse 1, 85764, Munich Neuherberg, Germany
    Anal Bioanal Chem 389:1033-45. 2007
  10. ncbi Differential analysis of Saccharomyces cerevisiae mitochondria by free flow electrophoresis
    Hans Zischka
    Institutes of Human Genetics and Toxicology, GSF National Research Center for Environment and Health, 85764 Munich Neuherberg, Germany
    Mol Cell Proteomics 5:2185-200. 2006

Collaborators

Detail Information

Publications14

  1. ncbi Improved proteome analysis of Saccharomyces cerevisiae mitochondria by free-flow electrophoresis
    Hans Zischka
    GSF Research Centre for Environment and Health, Institute of Human Genetics, Oberschleissheim, Germany
    Proteomics 3:906-16. 2003
    ..Therefore these results represent a feasible approach for an in-depth proteome analysis of mitochondria and possibly other organelles...
  2. doi Mitochondrial dynamics in yeast cell death and aging
    Ralf J Braun
    Institut fur Zellbiologie, Universitat Bayreuth, 95440 Bayreuth, Germany
    Biochem Soc Trans 39:1520-6. 2011
    ..We highlight the roles of the components of the mitochondrial fusion and fission machinery that affect and regulate cell death and aging...
  3. pmc A new Canterbury tale: the eighth International Meeting on Yeast Apoptosis in Canterbury, UK, 2-6 May 2011
    D Carmona-Gutierrez
    1 Institute of Molecular Biosciences, University of Graz, Graz, Austria 2 Institute of Biochemistry, Technical University of Graz, Graz, Austria
    Cell Death Differ 18:1948-9. 2011
  4. pmc Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast
    Ralf J Braun
    Institute of Molecular Biosciences, University of Graz, Graz, Austria
    J Biol Chem 286:19958-72. 2011
    ..These data demonstrate that mitochondria and oxidative stress are important to TDP-43-triggered cell death in yeast and may suggest a similar role in human TDP-43 pathologies...
  5. doi Nervous yeast: modeling neurotoxic cell death
    Ralf J Braun
    Institute of Molecular Biosciences, Department of Microbiology, Karl Franzens University of Graz, Graz, Austria
    Trends Biochem Sci 35:135-44. 2010
    ....
  6. doi 16-BAC/SDS-PAGE analysis of membrane proteins of yeast mitochondria purified by free flow electrophoresis
    Ralf J Braun
    GSF National Research Centre for Environment and Health, Institute of Human Genetics, Munich, Germany
    Methods Mol Biol 528:83-107. 2009
    ..Proteins were identified by Maldi-Tof mass spectrometry and peptide mass fingerprinting...
  7. doi Purification of Saccharomyces cerevisiae mitochondria by zone electrophoresis in a free flow device
    Hans Zischka
    GSF National Research Center for Environment and Health, Institute of Toxicology, Munich Neuherberg, Germany
    Methods Mol Biol 432:51-64. 2008
    ..The purified mitochondria can be collected by centrifugation and used for further experiments and analysis such as sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting, 2-DE or electron microscopy...
  8. doi Mechanisms of Cdc48/VCP-mediated cell death: from yeast apoptosis to human disease
    Ralf J Braun
    Institute of Human Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Munich Neuherberg, Germany
    Biochim Biophys Acta 1783:1418-35. 2008
    ..This complex role in cell death pathways could correspond with the various pathophysiological conditions Cdc48/VCP is involved in...
  9. ncbi Two-dimensional electrophoresis of membrane proteins
    Ralf J Braun
    GSF National Research Center for Environment and Health, Institute of Human Genetics, Ingolstaedter Landstrasse 1, 85764, Munich Neuherberg, Germany
    Anal Bioanal Chem 389:1033-45. 2007
    ..Finally, the separation of native membrane protein complexes through the application of blue and clear native gel electrophoresis (BN/CN-PAGE) is reviewed, as well as the free-flow electrophoresis (FFE) of membranes...
  10. ncbi Differential analysis of Saccharomyces cerevisiae mitochondria by free flow electrophoresis
    Hans Zischka
    Institutes of Human Genetics and Toxicology, GSF National Research Center for Environment and Health, 85764 Munich Neuherberg, Germany
    Mol Cell Proteomics 5:2185-200. 2006
    ..This result demonstrates that ZE-FFE may give important information on the specific properties of subpopulations of a mitochondrial preparation allowing a further detailed functional analysis...
  11. ncbi Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast
    Ralf J Braun
    GSF National Research Center for Environment and Health, Institute of Human Genetics, Ingolstaedter Landstrasse 1, Munich Neuherberg D 85764, Germany
    J Biol Chem 281:25757-67. 2006
    ..Concomitantly, emergence of caspase-like enzymatic activity occurs suggesting a role for caspases in the cell death process. These data strongly point for the first time to a mitochondrial involvement in Cdc48p/VCP-dependent apoptosis...
  12. ncbi MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria
    Mark Rinnerthaler
    Department of Cell Biology, Division of Genetics, University of Salzburg, Austria
    Biochim Biophys Acta 1757:631-8. 2006
    ..Our results so far indicate that Mmi1p is one of the few proteins establishing a functional link between microtubules and mitochondria which may be needed for correct localization of mitochondria during cell division...
  13. ncbi The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
    Christian Johannes Gloeckner
    GSF National Research Center for Environment and Health, Institute of Human Genetics, Munich Neuherberg, Germany
    Hum Mol Genet 15:223-32. 2006
    ..This suggests that the pathology of PD caused by the I2020T mutation is associated with an increase rather than a loss in LRRK2 kinase activity...
  14. doi Ceramide triggers metacaspase-independent mitochondrial cell death in yeast
    Didac Carmona-Gutierrez
    Institute of Molecular Biosciences, University of Graz, Graz, Austria
    Cell Cycle 10:3973-8. 2011
    ..Altogether, our results point to a pivotal role of mitochondria in ceramide-induced yeast cell death...