Miriam Bottlender

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Impact of craving on alcohol relapse during, and 12 months following, outpatient treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Nussbaumstrasse 7, 80336 Muenchen, Germany
    Alcohol Alcohol 39:357-61. 2004
  2. ncbi request reprint Chronological relationship between antisocial personality disorder and alcohol dependence
    M Bahlmann
    Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Eur Addict Res 8:195-200. 2002
  3. ncbi request reprint Neuroleptic malignant syndrome due to atypical neuroleptics: three episodes in one patient
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich
    Pharmacopsychiatry 35:119-21. 2002
  4. ncbi request reprint Are bipolar I depressive patients less responsive to treatment with antidepressants than unipolar depressive patients? Results from a case control study
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Eur Psychiatry 17:200-5. 2002
  5. ncbi request reprint Outpatient alcoholism treatment: predictors of outcome after 3 years
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Nussbaumstr 7, 80336 Munich, Germany
    Drug Alcohol Depend 80:83-9. 2005
  6. ncbi request reprint Negative symptoms in depressed and schizophrenic patients: how do they differ?
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Clin Psychiatry 64:954-8. 2003
  7. ncbi request reprint [Negative symptoms of schizophrenic patients from the perspective of psychiatrists, patients themselves and their relatives]
    R Bottlender
    Psychiatrische Klinik der LMU, Munchen
    Nervenarzt 74:762-6. 2003
  8. ncbi request reprint [Effectiveness of outpatient treatment for alcoholism - impact of personality disorders on course of treatment]
    Miriam Bottlender
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Ludwig Maximilians Universitat Munchen, Germany
    Psychother Psychosom Med Psychol 53:384-9. 2003
  9. ncbi request reprint Impact of different personality dimensions (NEO Five-Factor Inventory) on the outcome of alcohol-dependent patients 6 and 12 months after treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Psychiatry Res 136:61-7. 2005
  10. ncbi request reprint Efficacy of an intensive outpatient rehabilitation program in alcoholism: predictors of outcome 6 months after treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Addict Res 11:132-7. 2005

Collaborators

Detail Information

Publications82

  1. ncbi request reprint Impact of craving on alcohol relapse during, and 12 months following, outpatient treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Nussbaumstrasse 7, 80336 Muenchen, Germany
    Alcohol Alcohol 39:357-61. 2004
    ..1995) and relapse during and after completion of an intensive outpatient treatment programme...
  2. ncbi request reprint Chronological relationship between antisocial personality disorder and alcohol dependence
    M Bahlmann
    Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Eur Addict Res 8:195-200. 2002
    ..This finding suggests that in patients with ASPD, alcohol dependence might be a secondary syndrome as suggested by previous research...
  3. ncbi request reprint Neuroleptic malignant syndrome due to atypical neuroleptics: three episodes in one patient
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich
    Pharmacopsychiatry 35:119-21. 2002
    ..The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride. These episodes had some atypical features that will be discussed with regard to the pathophysiological mechanisms leading to NMS...
  4. ncbi request reprint Are bipolar I depressive patients less responsive to treatment with antidepressants than unipolar depressive patients? Results from a case control study
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Eur Psychiatry 17:200-5. 2002
    ....
  5. ncbi request reprint Outpatient alcoholism treatment: predictors of outcome after 3 years
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Nussbaumstr 7, 80336 Munich, Germany
    Drug Alcohol Depend 80:83-9. 2005
    ..This prospective study investigated predictors for relapse 3 years after completion of an intensive outpatient treatment programme for alcoholism...
  6. ncbi request reprint Negative symptoms in depressed and schizophrenic patients: how do they differ?
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Clin Psychiatry 64:954-8. 2003
    ..nonenduring) can help to improve their specificity for schizophrenia...
  7. ncbi request reprint [Negative symptoms of schizophrenic patients from the perspective of psychiatrists, patients themselves and their relatives]
    R Bottlender
    Psychiatrische Klinik der LMU, Munchen
    Nervenarzt 74:762-6. 2003
    ..These findings indicate that patients' and relatives' ratings could be used to reduce information variance and improve the validity of interview-based, assessed negative symptoms...
  8. ncbi request reprint [Effectiveness of outpatient treatment for alcoholism - impact of personality disorders on course of treatment]
    Miriam Bottlender
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Ludwig Maximilians Universitat Munchen, Germany
    Psychother Psychosom Med Psychol 53:384-9. 2003
    ..The present results indicate that patients with comorbid personality disorder can be successfully integrated into a high-structured outpatient therapy...
  9. ncbi request reprint Impact of different personality dimensions (NEO Five-Factor Inventory) on the outcome of alcohol-dependent patients 6 and 12 months after treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Psychiatry Res 136:61-7. 2005
    ..These results are in line with prior research on this topic...
  10. ncbi request reprint Efficacy of an intensive outpatient rehabilitation program in alcoholism: predictors of outcome 6 months after treatment
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Addict Res 11:132-7. 2005
    ..In summary, results of this study indicate a favorable outcome of socially stable alcohol-dependent patients and patients with a lower degree of depression, anxiety and craving in an intensive outpatient rehabilitation program...
  11. ncbi request reprint [Catamnestic study on the efficacy of an intensive outpatient treatment programme for alcohol-dependent patients: impact of participation in AA on the abstinence rates]
    M Bottlender
    Psychiatrische Klinik und Poliklinik, Ludwig Maximilians Universitat Munchen, Deutschland
    Fortschr Neurol Psychiatr 73:150-5. 2005
    ..Results indicate the predictive value of AA attendance for relapse prevention after controlling for confounding variables. The value of self-help-groups in the network of alcoholism treatment is discussed...
  12. ncbi request reprint The Kraepelinian dichotomy: preliminary results of a 15-year follow-up study on functional psychoses: focus on negative symptoms
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    Schizophr Res 56:87-94. 2002
    ..Overall, our study supports Kraepelin's original hypothesis that bifurcated the psychoses into the affective psychoses and schizophrenia, whereby the latter have a more deleterious long-term course and outcome...
  13. ncbi request reprint Deficit states in schizophrenia and their association with the length of illness and gender
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 251:272-8. 2001
    ..56). The findings are in line with the hypothesis that apart from a neurodevelopmental origin, the schizophrenic illness may also have a progressive neurodegenerative component, which clinically emerges as DS...
  14. ncbi request reprint Deficit syndromes in schizophrenic patients 15 years after their first hospitalisation: preliminary results of a follow-up study
    R Bottlender
    Psychiatrische Klinik, Ludwig Maximilians Universitat, Munchen, Germany
    Eur Arch Psychiatry Clin Neurosci 249:27-36. 1999
    ..Results are discussed with regard to the literature and to methodological limitations...
  15. ncbi request reprint Impact of duration of symptoms prior to first hospitalization on acute outcome in 998 schizophrenic patients
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336, Munich, Germany
    Schizophr Res 44:145-50. 2000
    ..Results indicate that most indicators of outcome were worse when the duration of symptoms was long. This was also true when age, gender, as well as the acuteness of illness were controlled for in the analyses...
  16. ncbi request reprint [What do medical students in the 6th clinical semester know about psychiatric emergencies?]
    R Bottlender
    Psychiatrische Klinik der LMU, Munchen
    Psychiatr Prax 27:286-90. 2000
    ..The aim of the present study was to evaluate the knowledge of medical students in psychiatric emergencies...
  17. ncbi request reprint The impact of duration of untreated psychosis and premorbid functioning on outcome of first inpatient treatment in schizophrenic and schizoaffective patients
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 252:226-31. 2002
    ..The aim of the study was to investigate the association between the duration of untreated psychosis, premorbid functioning and outcome from first inpatient treatment in schizophrenic or schizoaffective patients...
  18. ncbi request reprint Suicidality in bipolar compared to unipolar depressed inpatients
    R Bottlender
    Psychiatrische Klinik der Ludwig Maximilians Universität, Munchen
    Eur Arch Psychiatry Clin Neurosci 250:257-61. 2000
    ..A more pronounced depressive syndrome at time of admission was slightly associated with a lower risk of committing suicide...
  19. ncbi request reprint Mood-stabilisers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar I depressed patients
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Affect Disord 63:79-83. 2001
    ..The aim of this study was to give further support to the available evidence that mood stabilizers can reduce the risk of antidepressant-induced maniform switch phenomena in bipolar I depressed patients...
  20. ncbi request reprint Are low basal serum levels of the thyroid stimulating hormone (b-TSH) a risk factor for switches into states of expansive syndromes (known in Germany as "maniform syndromes" in bipolar I depression?
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 33:75-7. 2000
    ..4%) than in the group of patients with higher b-TSH (5.1 %). These findings suggest that lower b-TSH may be a risk factor for switching over from depression into "maniform" states in bipolar depressed patients...
  21. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
    ..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
  22. doi request reprint Depression-related variation in brain morphology over 3 years: effects of stress?
    Thomas S Frodl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Munich, Germany
    Arch Gen Psychiatry 65:1156-65. 2008
    ..Results of experimental studies suggest that neuroplastic changes may occur during depressive episodes. These effects have not been confirmed in patients with depression, to our knowledge...
  23. ncbi request reprint Syndromes and phenomenological subtypes underlying acute mania: a factor analytic study of 576 manic patients
    Tetsuya Sato
    Psychiatrische Klinik der Ludwig Maximilians Universität, Munchen, Germany
    Am J Psychiatry 159:968-74. 2002
    ..There is controversy as to whether atypical manic features such as aggression, psychosis, and depression are likely to coexist among manic patients. The authors' goal was to examine this controversy...
  24. ncbi request reprint Cincinnati criteria for mixed mania and suicidality in patients with acute mania
    Tetsuya Sato
    Psychiatrische Klinik und Poliklinik, Ludwig Maximilians Universitat, Munchen, Germany
    Compr Psychiatry 45:62-9. 2004
    ..Manic patients with suicidality may have a greater severity of residual depressive symptoms at discharge...
  25. ncbi request reprint Association of personality disorders with Type A and Type B alcoholics
    Miriam Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Muenchen, Germany
    Eur Arch Psychiatry Clin Neurosci 256:55-61. 2006
    ..The impact of other personality disorders does not play a substantial role in subtyping alcoholics...
  26. ncbi request reprint Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up
    Thomas Frodl
    Department of Psychiatry, Clinical Center Innenstadt, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Clin Psychiatry 65:492-9. 2004
    ....
  27. ncbi request reprint Prediction of symptom remission in schizophrenia during inpatient treatment
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 10:426-34. 2009
    ..The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission...
  28. ncbi request reprint Striatal dopamine transporter availability is associated with the productive psychotic state in first episode, drug-naive schizophrenic patients
    G J E Schmitt
    Department of Psychiatry, Ludwig Maximilians University Munich, 80336, Munchen, Germany
    Eur Arch Psychiatry Clin Neurosci 256:115-21. 2006
    ..Association of DAT availability and the acute psychotic syndrome is now demonstrated in a large cohort of first episode, never treated schizophrenic patients...
  29. ncbi request reprint Distinct seasonality of depressive episodes differentiates unipolar depressive patients with and without depressive mixed states
    Tetsuya Sato
    Psychiatric Hospital, Ludwig Maximilian University, Nussbaumstr 7, D 80336 Munich, Germany
    J Affect Disord 90:1-5. 2006
    ..The seasonality of depressive episodes is indicated to be different between unipolar and bipolar depressions. We therefore explored the seasonal pattern of depressive episodes in unipolar depressive patients with DMX...
  30. ncbi request reprint Classification of functional psychoses and its implication for prognosis: comparison between ICD-10 and DSM-IV
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychopathology 37:110-7. 2004
    ..The aim was to examine the agreement and differences between ICD-10 and DSM-IV in the classification of functional psychoses. Sampling and..
  31. doi request reprint Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study
    Eva M Meisenzahl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Nussbaumstrasse 7, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:127-37. 2010
    ....
  32. ncbi request reprint Evaluating the inter-episode stability of depressive mixed states
    Tetsuya Sato
    Psychiatric Hospital, Ludwig Maximilian University LMU, Nussbaumstr 7, D 80336 Munich, Germany
    J Affect Disord 81:103-13. 2004
    ..Our goal was to provide preliminary evidence of the inter-episode stability of DMX. The inter-episode stability is known to be an important validator for establishing a distinct clinical entity...
  33. doi request reprint Neuroanatomical correlates of executive dysfunction in the at-risk mental state for psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:160-74. 2010
    ....
  34. doi request reprint Anterior cingulate cortex does not differ between patients with major depression and healthy controls, but relatively large anterior cingulate cortex predicts a good clinical course
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 163:76-83. 2008
    ..These findings suggest that ACC volumes are not altered in patients with major depression, but that patients with larger ACC have a better clinical outcome than patients with smaller ACC...
  35. doi request reprint The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: comparison of psychopathological and psychosocial course and outcome and prediction of chronicity
    Hans Jurgen Moller
    Department of Psychiatry, University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:367-84. 2010
    ..The Strauss-Carpenter Scale, male gender as well as several psychopathological syndromes are the most relevant predictors for chronicity...
  36. ncbi request reprint Structural correlates of psychopathological symptom dimensions in schizophrenia: a voxel-based morphometric study
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Neuroimage 39:1600-12. 2008
    ..Thus, structural heterogeneity in schizophrenia may relate to specific patterns of GMD reductions that possibly share a common prefrontal-perisylvian pattern of structural brain alterations...
  37. ncbi request reprint Clinical correlates of later violence and criminal offences in schizophrenia
    Michael Soyka
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstr 7, 80336 Munich, Germany
    Schizophr Res 94:89-98. 2007
    ..Violence and criminality in patients with schizophrenia has been described in several studies but prediction of later criminal behavior is difficult...
  38. ncbi request reprint Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy and Radiology, Ludwig Maximilians University, Munich, Germany
    Arch Gen Psychiatry 64:410-6. 2007
    ..Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity, which is believed to be altered in patients with major depression...
  39. pmc Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disorders
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007
    ..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
  40. pmc Reduced hippocampal volume correlates with executive dysfunctioning in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    J Psychiatry Neurosci 31:316-23. 2006
    ..We aimed to investigate whether reduced hippocampal volumes correlate with executive dysfunctioning or memory dysfunctioning or with depression severity...
  41. ncbi request reprint Fifteen-year follow-up of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition depressive disorders: the prognostic significance of psychotic features
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, D 80336 Munich, Germany
    Compr Psychiatry 46:322-7. 2005
    ..The findings indicating low prognostic significance of psychotic symptoms in depressive disorders are in line with the broad concept of affective disorders in DSM-IV...
  42. doi request reprint Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Arch Gen Psychiatry 66:700-12. 2009
    ..Recently, machine learning algorithms have been successfully used for magnetic resonance imaging-based diagnostic classification of neuropsychiatric patient populations...
  43. pmc Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study
    Thomas Frodl
    Department of Psychiatry, Trinity College Dublin, Ireland
    J Psychiatry Neurosci 33:423-30. 2008
    ..We sought to examine the changes in hippocampal and amygdala volumes at baseline and at 3 years after an acute depressive episode, and the impact of reduced hippocampal volumes on the outcome...
  44. doi request reprint Use of neuroanatomical pattern regression to predict the structural brain dynamics of vulnerability and transition to psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:175-87. 2010
    ..To date, it is unknown whether these dynamic brain changes can be predicted at the single-subject level prior to disease transition using MRI-based machine-learning techniques...
  45. ncbi request reprint On the descriptive validity of ICD-10 schizophrenia: empirical analyses in the spectrum of non-affective functional psychoses
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychopathology 36:152-9. 2003
    ..The results are in line with a high descriptive validity of ICD-10 schizophrenia and highlight the importance of negative symptoms for this diagnosis...
  46. ncbi request reprint The impact of the duration of untreated psychosis prior to first psychiatric admission on the 15-year outcome in schizophrenia
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    Schizophr Res 62:37-44. 2003
    ..However, only few prospective studies have attempted to address a possible association between DUP and long-term outcome...
  47. ncbi request reprint Is there evidence for a male depressive syndrome in inpatients with major depression?
    Anne Maria Möller-Leimkühler
    Department of Psychiatry, Ludwig Maximilians University, D 80336 Munich, Germany
    J Affect Disord 80:87-93. 2004
    ....
  48. ncbi request reprint Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 53:338-44. 2003
    ..The aim of our study was to test the hypothesis that amygdala volumes are reduced in patients with recurrent major depression compared with first episode patients...
  49. ncbi request reprint Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 120:85-9. 2003
    ..05). However, after correction for multiple testing (Bonferroni) these results did not remain significant. Nevertheless, these findings suggest that the presence of the C allele might be an indicator for antidepressant treatment response...
  50. ncbi request reprint Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    Arch Gen Psychiatry 61:177-83. 2004
    ..Several studies have found reciprocal interactions between the serotonergic system and both brain-derived neurotrophic factor and glutamate, which are known to modulate or affect hippocampal morphologic characteristics...
  51. ncbi request reprint The gamma amino butyric acid (GABA) receptor alpha-3 subunit gene polymorphism in unipolar depressive disorder: a genetic association study
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstrasse 7, D 80336 Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 126:82-7. 2004
    ....
  52. ncbi request reprint Psychopathology of early-onset versus late-onset schizophrenia revisited: an observation of 473 neuroleptic-naive patients before and after first-admission treatments
    Tetsuya Sato
    Psychiatric Hospital, Ludwig Maximilian University Munich, Nussbaumstr 7, 80336 Munich, Germany
    Schizophr Res 67:175-83. 2004
    ....
  53. doi request reprint Reduced gray matter brain volumes are associated with variants of the serotonin transporter gene in major depression
    T Frodl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Munich, Germany
    Mol Psychiatry 13:1093-101. 2008
    ..Patients with depression show reduced GM volumes, particularly when they are homozygous for the L(A)-allele, suggesting that these patients are more vulnerable for morphological changes during depressive episodes...
  54. doi request reprint Time course of antipsychotic treatment response in schizophrenia: results from a naturalistic study in 280 patients
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Schizophr Res 118:183-8. 2010
    ..To describe the course of positive and negative symptoms during inpatient treatment and examine remission and response rates under routine clinical care conditions...
  55. ncbi request reprint Frequency of manic symptoms during a depressive episode and unipolar 'depressive mixed state' as bipolar spectrum
    T Sato
    Psychiatrische Klinik, Ludwig Maximilian University, Munich, Germany
    Acta Psychiatr Scand 107:268-74. 2003
    ..To report the frequency of intra-episode manic symptoms in depressive episodes, and to evaluate unipolar depressive mixed state (DMS) as bipolar spectrum...
  56. ncbi request reprint [Diagnostic shifts of functional psychoses in the transition from ICD-9 to ICD-10]
    M Jager
    Psychiatrische Klinik, Ludwig Maximilians Universitat, Nussbaumstrasse 7, 80336 Munchen
    Nervenarzt 74:420-7. 2003
    ..Nevertheless, ICD-10 diagnoses have gained in predictive validity because schizophrenia was further narrowed to cases with a more unfavourable outcome...
  57. doi request reprint Structural brain alterations at different stages of schizophrenia: a voxel-based morphometric study
    E M Meisenzahl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Schizophr Res 104:44-60. 2008
    ..Furthermore, our data suggest that in the advanced stages of schizophrenia additional cortical and subcortical brain areas become involved in the disease process. Longitudinal data will be required to further test this hypothesis...
  58. ncbi request reprint Combined action of the ACE D- and the G-protein beta3 T-allele in major depression: a possible link to cardiovascular disease?
    B Bondy
    Psychiatric Department of University Munich, Nussbaumstrasse 7, D 80336 Munich, Germany
    Mol Psychiatry 7:1120-6. 2002
    ..Nevertheless our study reports for the first time that the same allelic combination of two genes that have been shown to increase the risk for myocardial infarction (Naber et al, 2000) increase the vulnerability for depressive disorder...
  59. doi request reprint Structural brain alterations in subjects at high-risk of psychosis: a voxel-based morphometric study
    E M Meisenzahl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Schizophr Res 102:150-62. 2008
    ..These regions are compatible with structural findings in the clinically apparent disease of schizophrenia...
  60. ncbi request reprint Dipole localization of P300 and normal aging
    T Frodl
    Dept of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Brain Topogr 13:3-9. 2000
    ..Age affected both P300 subcomponents' latencies. Therefore, the functionally different alteration of P300 subcomponents might be the reason for P300 topography changes with the P300 maximum more frontally in older age...
  61. ncbi request reprint The loudness dependency of the auditory evoked N1/P2-component as a predictor of the acute SSRI response in depression
    J Gallinat
    Department of Psychiatry, Free University Berlin, Germany
    Psychopharmacology (Berl) 148:404-11. 2000
    ..In animal and human data there is a growing amount of evidence that a strong loudness dependency of late auditory evoked potentials (LDAEP) is an indicator of low serotonergic activity and vice versa...
  62. ncbi request reprint Course and outcome of first-admitted patients with acute and transient psychotic disorders (ICD-10:F23). Focus on relapses and social adjustment
    M Jäger M D
    Psychiatrische Klinik der Ludwig Maximilians Universität, Nussbaumstr 7, 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 253:209-15. 2003
    ..The aim of the present study was to investigate course and outcome of acute and transient psychotic disorders (ATPD)...
  63. ncbi request reprint [Schizophrenics in the doctor's office. Diagnostic and therapeutic aspects]
    R Bottlender
    Klinik fur Psychiatrie und Psychotherapie, and LMU München
    MMW Fortschr Med 146:19-23. 2004
    ..Today, medical treatment employs atypical neuroleptics, and treatment should be initiated as early as possible...
  64. ncbi request reprint Thalamic volume in first-episode and chronic schizophrenic subjects: a volumetric MRI study
    U W Preuss
    Department of Psychiatry, Psychiatrische Klinik und Poliklinik, Ludwig Maximilians Universitat Munchen, Nussbaumstr 7, 80336 Munchen, Germany
    Schizophr Res 73:91-101. 2005
    ....
  65. ncbi request reprint Irritable psychomotor elation in depressed inpatients: a factor validation of mixed depression
    T Sato
    Psychiatrische Klinik, Ludwig Maximilians Universitat Munchen, Nussbaumstrasse 7 80336 Munich, Germany
    J Affect Disord 84:187-96. 2005
    ..Early authors described hypomanic symptoms as mixed features in depressive episode, but this syndrome has not been sufficiently explored in previous studies...
  66. ncbi request reprint [The classification of functional psychoses: the impact of ICD-10 diagnoses (research diagnostic criteria) for the prediction of the long-term course]
    M Jager
    Psychiatrische Klinik der Ludwig Maximilians Universität München
    Fortschr Neurol Psychiatr 72:70-8. 2004
    ..The results revealed that the predictive validity of the dimensional model (77 %) does not exceed the predictive validity of ICD-10 diagnoses (78 %)...
  67. ncbi request reprint [Diagnostics and therapy of depressive symptoms in schizophrenic patients]
    R Bottlender
    Klinik fur Psychiatrie und Psychotherapie, LMU Munchen
    MMW Fortschr Med 147:59-62. 2005
    ..In regards to this circumstance, a rethinking is desirable and, as a matter of principle, necessary...
  68. ncbi request reprint [Modern therapy for dementia]
    F Padberg
    Oberarzt der Klinik fur Psychiatrie und Psychotherapie, LMU Munchen
    MMW Fortschr Med 147:71-4, 76-7. 2005
    ..During the last decade, the classic neuroleptics and benzodiazepine have been largely replaced by modern antidepressants, atypical antipsychotics and benzodiazepine analogues...
  69. ncbi request reprint Antidepressant-associated maniform states in acute treatment of patients with bipolar-I depression
    R Bottlender
    Psychiatrische Klinik der Ludwig Maximilians Universität, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 248:296-300. 1998
    ..The switch phenomenon was not associated with sociodemographic or clinical data...
  70. ncbi request reprint Fifteen-year follow-up of ICD-10 schizoaffective disorders compared with schizophrenia and affective disorders
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Acta Psychiatr Scand 109:30-7. 2004
    ..The aim of the present study was to compare ICD-10 schizoaffective disorders to schizophrenia and affective disorders with respect to the clinical picture and the long-term outcome...
  71. ncbi request reprint Long-term inter-episode stability of syndromes underlying mania
    T Sato
    Psychiatric Hospital, Ludwig Maximilian University, Munich, Germany
    Acta Psychiatr Scand 108:310-3. 2003
    ..To explore the stability of diverse manic presentations across manic recurrences...
  72. ncbi request reprint Neurochemical substrates and neuroanatomical generators of the event-related P300
    T Frodl-Bauch
    Department of Clinical Neurophysiology and Department of Psychiatry, Ludwig Maximilians Universitat Munchen, Deutschland
    Neuropsychobiology 40:86-94. 1999
    ..The knowledge of the generating structures of P300 is summarized from intracranial studies, magnetoencephalographic investigations, lesion and animal studies...
  73. ncbi request reprint Are antidepressants less effective in the acute treatment of bipolar I compared to unipolar depression?
    H J Moller
    Department of Psychiatry of the Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Affect Disord 67:141-6. 2001
    ..Using our routine documentation system we evaluated the hypothesis that antidepressants may be less effective in the acute treatment of bipolar I depressed patients compared to unipolar depressed patients...
  74. ncbi request reprint [One drink, one drunk--controlled drinking by alcoholics? 3-year-outcome after intensive outpatient treatment]
    Miriam Bottlender
    Psychiatrische Klinik und Poliklinik, Ludwig Maximilians Universitat Munchen
    Psychother Psychosom Med Psychol 57:32-8. 2007
    ..In the present study we examined in a sample of alcohol-dependent patients whether or not controlled drinking is possible during a three years period following treatment...
  75. ncbi request reprint Enlargement of the amygdala in patients with a first episode of major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 51:708-14. 2002
    ..The aim of the present study was to measure the amygdala volumes in patients with a first episode of major depression...
  76. ncbi request reprint The boundary between mixed and manic episodes in the ICD-10 classification
    T Sato
    Psychiatrische Klinik und Poliklinik, LMU Munich, Germany
    Acta Psychiatr Scand 106:109-16. 2002
    ..To investigate the boundary between ICD-10 mixed and manic episodes, which has apparently remained understudied...
  77. ncbi request reprint The serotonin syndrome scale: first results on validity
    U Hegerl
    , , , Germany
    Eur Arch Psychiatry Clin Neurosci 248:96-103. 1998
    ..Using a SSS > 6 as diagnostic criterion, mild serotonin syndromes were diagnosed in 5 of our 42 patients. The Serotonin syndrome scale may become a useful tool for clinicians and scientists dealing with the serotonin syndrome...
  78. ncbi request reprint Hippocampal changes in patients with a first episode of major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    Am J Psychiatry 159:1112-8. 2002
    ..A core area in these networks is the hippocampus. In the present study, differences in volumes of hippocampal gray and white matter between patients with a first episode of major depression and healthy comparison subjects were examined...
  79. ncbi request reprint Mixed depressive features predict maniform switch during treatment of depression in bipolar I disorder
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Affect Disord 78:149-52. 2004
    ..Case observations imply that depressed patients with mixed features are of high risk for maniform switch during acute treatment...
  80. doi request reprint Standardized remission criteria in schizophrenia: descriptive validity and comparability with previously used outcome measures
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 41:190-5. 2008
    ..Standardized consensus criteria for remission in schizophrenia were recently proposed. As yet, the validity of these criteria and their comparability with previously used outcome measures are unclear...
  81. doi request reprint Neuroanatomical correlates of different vulnerability states for psychosis and their clinical outcomes
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Luwdig Maxmilians University, 80336 Munich, Germany
    Br J Psychiatry 195:218-26. 2009
    ..Structural brain abnormalities have been described in individuals with an at-risk mental state for psychosis. However, the neuroanatomical underpinnings of the early and late at-risk mental state relative to clinical outcome remain unclear...
  82. ncbi request reprint [For and against: controlled drinking as useful and necessary treatment alternative]
    Joachim Körkel
    Ev Fachhochschule Nürnberg, Bärenschanzstrasse 4, 90429 Nürnberg
    Psychiatr Prax 32:324-6. 2005