Elisa Bombarda

Summary

Affiliation: University of Bayreuth
Country: Germany

Publications

  1. ncbi request reprint DNA-induced dimerization of poly(ADP-ribose) polymerase-1 triggers its activation
    Emmanuelle Pion
    UMR 7034 du CNRS, Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Universite Louis Pasteur de Strasbourg, 74, route du Rhin, F 67401 Illkirch Cedex, France
    Biochemistry 44:14670-81. 2005
  2. pmc Molecular mechanism of the Zn2+-induced folding of the distal CCHC finger motif of the HIV-1 nucleocapsid protein
    Elisa Bombarda
    UMR 7175, Centre National de la Recherche Scientifique, Universite Louis Pasteur, Faculte de Pharmacie, Illkirch, France
    Biophys J 93:208-17. 2007
  3. ncbi request reprint Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein
    Elisa Bombarda
    UMR 7034 du CNRS, Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Faculte de Pharmacie, Universite Louis Pasteur, 74, route du Rhin, F 67401 Illkirch Cedex, France
    Biochemistry 44:7315-25. 2005
  4. ncbi request reprint Structure of the His44 --> Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: a combined NMR, molecular dynamics simulation, and fluorescence study
    Roland H Stote
    Laboratoire de Chimie Biophysique, ISIS UMR 7006 CNRS, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, F 67083 Strasbourg cedex, France
    Biochemistry 43:7687-97. 2004
  5. doi request reprint Investigating the mechanisms of photosynthetic proteins using continuum electrostatics
    G Matthias Ullmann
    Structural Biology Bioinformatics, University of Bayreuth, Universitätsstr 30, BGI, Bayreuth 95447, Germany
    Photosynth Res 97:33-53. 2008
  6. ncbi request reprint Theoretical investigation of the behavior of titratable groups in proteins
    Astrid R Klingen
    Structural Biology Bioinformatics, University of Bayreuth, Universitatsstrasse 30, BGI, D 95447 Bayreuth, Germany
    Photochem Photobiol Sci 5:588-96. 2006
  7. ncbi request reprint Influence of the membrane potential on the protonation of bacteriorhodopsin: insights from electrostatic calculations into the regulation of proton pumping
    Elisa Bombarda
    Structural Biology Bioinformatics, University of Bayreuth, Universitätsstr 30, BGI, 95447 Bayreuth, Germany
    J Am Chem Soc 128:12129-39. 2006

Collaborators

Detail Information

Publications7

  1. ncbi request reprint DNA-induced dimerization of poly(ADP-ribose) polymerase-1 triggers its activation
    Emmanuelle Pion
    UMR 7034 du CNRS, Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Universite Louis Pasteur de Strasbourg, 74, route du Rhin, F 67401 Illkirch Cedex, France
    Biochemistry 44:14670-81. 2005
    ..Taken together, our data allow further characterization of the features of hPARP-1 recognition in damaged cells and bring additional evidence that hPARP-1 may also play a role in undamaged cells...
  2. pmc Molecular mechanism of the Zn2+-induced folding of the distal CCHC finger motif of the HIV-1 nucleocapsid protein
    Elisa Bombarda
    UMR 7175, Centre National de la Recherche Scientifique, Universite Louis Pasteur, Faculte de Pharmacie, Illkirch, France
    Biophys J 93:208-17. 2007
    ..Due to their critical role in folding, the intermediates identified for the first time in this study may constitute potential targets for HIV therapy...
  3. ncbi request reprint Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein
    Elisa Bombarda
    UMR 7034 du CNRS, Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Faculte de Pharmacie, Universite Louis Pasteur, 74, route du Rhin, F 67401 Illkirch Cedex, France
    Biochemistry 44:7315-25. 2005
    ..3 and approximately 10(3) s(-)(1), respectively, for Ser49(35-50)NCp7 and approximately 4 x 10(-)(3) and approximately 500 s(-)(1), respectively, for Ala44(35-50)NCp7...
  4. ncbi request reprint Structure of the His44 --> Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: a combined NMR, molecular dynamics simulation, and fluorescence study
    Roland H Stote
    Laboratoire de Chimie Biophysique, ISIS UMR 7006 CNRS, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, F 67083 Strasbourg cedex, France
    Biochemistry 43:7687-97. 2004
    ..Modeling of the DNA:NCp7 complex using structures of the variant peptide suggests that the residues forming a hydrophobic cleft in the native protein are improperly oriented for efficient DNA binding by the variant peptide...
  5. doi request reprint Investigating the mechanisms of photosynthetic proteins using continuum electrostatics
    G Matthias Ullmann
    Structural Biology Bioinformatics, University of Bayreuth, Universitätsstr 30, BGI, Bayreuth 95447, Germany
    Photosynth Res 97:33-53. 2008
    ..Simulations as those reviewed in this article help to analyze molecular mechanisms on the basis of the structure of the protein, guide new experiments, and provide a better and deeper understanding of protein functions...
  6. ncbi request reprint Theoretical investigation of the behavior of titratable groups in proteins
    Astrid R Klingen
    Structural Biology Bioinformatics, University of Bayreuth, Universitatsstrasse 30, BGI, D 95447 Bayreuth, Germany
    Photochem Photobiol Sci 5:588-96. 2006
    ....
  7. ncbi request reprint Influence of the membrane potential on the protonation of bacteriorhodopsin: insights from electrostatic calculations into the regulation of proton pumping
    Elisa Bombarda
    Structural Biology Bioinformatics, University of Bayreuth, Universitätsstr 30, BGI, 95447 Bayreuth, Germany
    J Am Chem Soc 128:12129-39. 2006
    ..Our calculations give new insights into the mechanism with which bacteriorhodopsin senses the membrane potential and the pH gradient and how the proton pumping is regulated by these parameters...