Elfriede H Bollschweiler

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint Benefits and limitations of Kaplan-Meier calculations of survival chance in cancer surgery
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Langenbecks Arch Surg 388:239-44. 2003
  2. pmc Evaluation of POSSUM scoring system in patients with gastric cancer undergoing D2-gastrectomy
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Str, 9, 50931 Koln, Germany
    BMC Surg 5:8. 2005
  3. ncbi request reprint Alternative shift models and the quality of patient care. An empirical study in surgical intensive care units
    E Bollschweiler
    Klinik und Poliklinik für Visceral und Gefässchirurgie der Universität zu Köln, Joseph Stelzmann Str 9, D 50931 Köln
    Langenbecks Arch Surg 386:104-9. 2001
  4. ncbi request reprint Bile reflux into the stomach and the esophagus for volunteers older than 40 years
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Digestion 71:65-71. 2005
  5. ncbi request reprint Artificial neural network for prediction of lymph node metastases in gastric cancer: a phase II diagnostic study
    Elfriede H Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Germany
    Ann Surg Oncol 11:506-11. 2004
  6. ncbi request reprint Vitamin intake and risk of subtypes of esophageal cancer in Germany
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    J Cancer Res Clin Oncol 128:575-80. 2002
  7. ncbi request reprint Demographic variations in the rising incidence of esophageal adenocarcinoma in white males
    E Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Cancer 92:549-55. 2001
  8. ncbi request reprint [Carcinoma of the esophagus--actual epidemiology in Germany]
    E Bollschweiler
    Klinik und Poliklinik für Visceral und Gefässchirurgie der Universität zu Köln
    Onkologie 24:180-4. 2001
  9. doi request reprint ERCC1 RNA expression in peripheral blood predicts minor histopathological response to neoadjuvant radio-chemotherapy in patients with locally advanced cancer of the esophagus
    Jan Brabender
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Str 9, 50931, Cologne, Germany
    J Gastrointest Surg 12:1815-21. 2008
  10. pmc Histomorphologic tumor regression and lymph node metastases determine prognosis following neoadjuvant radiochemotherapy for esophageal cancer: implications for response classification
    Paul M Schneider
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Ann Surg 242:684-92. 2005

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Benefits and limitations of Kaplan-Meier calculations of survival chance in cancer surgery
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Langenbecks Arch Surg 388:239-44. 2003
    ..However, mistakes and distortions frequently arise in the display and interpretation of survival plots. This review aims to highlight such pitfalls and provide recommendations for future practice...
  2. pmc Evaluation of POSSUM scoring system in patients with gastric cancer undergoing D2-gastrectomy
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Str, 9, 50931 Koln, Germany
    BMC Surg 5:8. 2005
    ..The aim of the present study was to assess the accuracy of POSSUM in predicting mortality and morbidity in patients with gastric cancer undergoing D2-gastrectomy...
  3. ncbi request reprint Alternative shift models and the quality of patient care. An empirical study in surgical intensive care units
    E Bollschweiler
    Klinik und Poliklinik für Visceral und Gefässchirurgie der Universität zu Köln, Joseph Stelzmann Str 9, D 50931 Köln
    Langenbecks Arch Surg 386:104-9. 2001
    ..The intention of this law is to protect the physician and to create better conditions for the patients. However, a systematic evaluation of the postulated benefits is still lacking...
  4. ncbi request reprint Bile reflux into the stomach and the esophagus for volunteers older than 40 years
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Digestion 71:65-71. 2005
    ..The volunteers serving as controls in those studies were significantly younger than the patients. The aim of this study was to analyze bile reflux patterns of healthy volunteers aged comparably to patients with Barrett's esophagus...
  5. ncbi request reprint Artificial neural network for prediction of lymph node metastases in gastric cancer: a phase II diagnostic study
    Elfriede H Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Germany
    Ann Surg Oncol 11:506-11. 2004
    ..The aim of this study was to evaluate artificial neural networks (ANN) for predicting LNM in patients with gastric cancer and to compare the predictive power with that of MCP...
  6. ncbi request reprint Vitamin intake and risk of subtypes of esophageal cancer in Germany
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    J Cancer Res Clin Oncol 128:575-80. 2002
    ..The goal of this pilot-study was to analyze the influence of daily vitamin consumption on the frequency of esophageal carcinoma in Germany...
  7. ncbi request reprint Demographic variations in the rising incidence of esophageal adenocarcinoma in white males
    E Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Cancer 92:549-55. 2001
    ..The purpose of the current investigation was to collect the available data and to analyze them in a unified manner...
  8. ncbi request reprint [Carcinoma of the esophagus--actual epidemiology in Germany]
    E Bollschweiler
    Klinik und Poliklinik für Visceral und Gefässchirurgie der Universität zu Köln
    Onkologie 24:180-4. 2001
    ..The preoperative risk factors of patients with SCC are caused by tobacco and alcohol. Only patients with early cancer (pT1) of the esophagus have a good prognosis with a 5-year survival rate of 83% for AC and 63% for SCC...
  9. doi request reprint ERCC1 RNA expression in peripheral blood predicts minor histopathological response to neoadjuvant radio-chemotherapy in patients with locally advanced cancer of the esophagus
    Jan Brabender
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Str 9, 50931, Cologne, Germany
    J Gastrointest Surg 12:1815-21. 2008
    ....
  10. pmc Histomorphologic tumor regression and lymph node metastases determine prognosis following neoadjuvant radiochemotherapy for esophageal cancer: implications for response classification
    Paul M Schneider
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Ann Surg 242:684-92. 2005
    ..We sought to quantitatively and objectively evaluate histomorphologic tumor regression and establish a relevant prognostic regression classification system for esophageal cancer patients receiving neoadjuvant radiochemotherapy...
  11. ncbi request reprint Reduced incidence of nodal micrometastasis after major response to neoadjuvant chemoradiation in locally advanced esophageal cancer
    Klaus L Prenzel
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Ann Surg Oncol 14:954-9. 2007
    ..The influence on nodal micrometastasis has not yet been evaluated...
  12. ncbi request reprint High cyclooxygenase-2 expression following neoadjuvant radiochemotherapy is associated with minor histopathologic response and poor prognosis in esophageal cancer
    Huan Xi
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Clin Cancer Res 11:8341-7. 2005
    ..We analyzed the association of COX-2 mRNA and protein expression with histomorphologic response to neoadjuvant radiochemotherapy in esophageal cancer...
  13. ncbi request reprint Overexpression of survivin mRNA is associated with a favorable prognosis following neoadjuvant radiochemotherapy in esophageal cancer
    Ute Warnecke-Eberz
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Oncol Rep 13:1241-6. 2005
    ..However, overexpression of survivin mRNA in pretreatment biopsies (T/N ratio >1) was associated with superior survival probabilities...
  14. ncbi request reprint Staging of esophageal carcinoma: length of tumor and number of involved regional lymph nodes. Are these independent prognostic factors?
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Germany
    J Surg Oncol 94:355-63. 2006
    ..The aim of this study was to analyze the prognostic relevance of tumor length as well as number of involved regional lymph nodes (LNM) in patients with esophageal carcinoma...
  15. doi request reprint Response evaluation by endoscopy, rebiopsy, and endoscopic ultrasound does not accurately predict histopathologic regression after neoadjuvant chemoradiation for esophageal cancer
    Paul M Schneider
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Ann Surg 248:902-8. 2008
    ....
  16. doi request reprint Quantitative analysis of survivin RNA expression in blood as a non-invasive predictor of response to neoadjuvant radiochemotherapy in esophageal cancer
    Peter Grimminger
    Department of General, Visceral, and Tumor Surgery, University of Cologne, 50931Cologne, Germany
    J Surg Oncol 100:447-51. 2009
    ..Analysis of survivin RNA expression in peripheral blood as a non-invasive molecular predictor of response to neoadjuvant radiochemotherapy in patients with locally advanced cancer of the esophagus...
  17. doi request reprint Extracapsular lymph node involvement differs between squamous cell and adenocarcinoma of the esophagus
    Ralf Metzger
    Department of General, Visceral, and Cancer Surgery, University of Cologne, Germany
    Ann Surg Oncol 16:447-53. 2009
    ..005) higher in patients with pN1 AC (median = 5) compared with pN1 SCC (median = 3). We conclude that extracapsular LNI is an independent negative prognostic factor which occurs more frequently in esophageal AC than SCC...
  18. doi request reprint Ivor-Lewis esophagectomy with and without laparoscopic conditioning of the gastric conduit
    Wolfgang Schroder
    Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Str 62, 50937, Cologne, Germany
    World J Surg 34:738-43. 2010
    ..Modifications of this standard procedure aim to reduce postoperative morbidity and mortality...
  19. ncbi request reprint [18F]-Fluorodeoxyglucose-positron emission tomography for the assessment of histopathologic response and prognosis after completion of neoadjuvant chemoradiation in esophageal cancer
    Daniel Vallbohmer
    General, Visceral, and Cancer Surgery, University of Cologne, Germany
    Ann Surg 250:888-94. 2009
    ....
  20. doi request reprint Mean and maximum standardized uptake values in [18F]FDG-PET for assessment of histopathological response in oesophageal squamous cell carcinoma or adenocarcinoma after radiochemotherapy
    Matthias Schmidt
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Eur J Nucl Med Mol Imaging 36:735-44. 2009
    ..To evaluate the potential of [(18)F]fluorodeoxyglucose positron emission tomography (FDG-PET) for the assessment of histopathological response and survival after neoadjuvant radiochemotherapy in patients with oesophageal cancer...
  21. ncbi request reprint Histological grading in gastric cancer by Ming classification: correlation with histopathological subtypes, metastasis, and prognosis
    Thomas Luebke
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, Cologne 50931, Germany
    World J Surg 29:1422-7; discussion 1428. 2005
    ..The 3-year survival rates were lower in the infiltrative tumor type than in the expansive tumor type according to Ming. However, the Ming classification is not an independent prognostic factor...
  22. ncbi request reprint The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation
    Uta Drebber
    Institute of Pathology, University of Cologne, Cologne, Germany
    Oncol Rep 19:1477-83. 2008
    ..P21 proved to be a significant prognostic factor in the multivariate analysis. Our data suggest that the overexpression of c-met and p21 may represent independent prognostic factors in gastric carcinoma...
  23. doi request reprint High prevalence of colonic polyps in white males with esophageal adenocarcinoma
    Elfriede Bollschweiler
    Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany
    Dis Colon Rectum 52:299-304. 2009
    ..There is ongoing discussion regarding Barrett's esophagus and the prevalence of colonic neoplasms. The goal of this investigation was to evaluate colonoscopic findings in patients with esophageal carcinoma...
  24. doi request reprint Histologic tumor type and the rate of complete response after neoadjuvant therapy for esophageal cancer
    Elfriede Bollschweiler
    Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Str 62, 50937 Koln, Germany
    Future Oncol 6:25-35. 2010
    ..However, when the tumor does respond, the rate of pCR with increasing dosage of chemoradiotherapy increases more rapidly in AC patients than in SCC patients...
  25. doi request reprint Death-associated protein kinase (DAPK) promoter methylation and response to neoadjuvant radiochemotherapy in esophageal cancer
    Jan Brabender
    Department of General, Visceral and Tumor Surgery, University of Cologne, Cologne, Germany
    Ann Surg Oncol 16:1378-83. 2009
    ....
  26. doi request reprint Leukocyte depletion in allogeneic blood transfusion does not change the negative influence on survival following transthoracic resection for esophageal cancer
    Frederike C Ling
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    J Gastrointest Surg 13:581-6. 2009
    ..This study evaluates the association between receipt of leucocyte-depleted and non-depleted allogeneic blood and survival following esophagectomy for cancer...
  27. ncbi request reprint Impact of antireflux surgery on Barrett's esophagus
    Christian A Gutschow
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Strasse 9, 50931 Cologne, Germany
    Langenbecks Arch Surg 387:138-45. 2002
    ..The rising incidence of Barrett's carcinoma is a matter of major concern in Western societies. We realized a review of the literature to evaluate the impact of antireflux surgery on prevention of Barrett's carcinoma...
  28. doi request reprint Early gastric cancer: lymph node metastasis starts with deep mucosal infiltration
    Arnulf H Holscher
    Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener St 62, D 50937 Cologne, Germany
    Ann Surg 250:791-7. 2009
    ..The purpose of this study was to evaluate the frequency of lymph node metastasis according to the depth of tumor infiltration of the mucosa and submucosa...
  29. doi request reprint XRCC1 gene polymorphism for prediction of response and prognosis in the multimodality therapy of patients with locally advanced rectal cancer
    Peter P Grimminger
    Department of General, Visceral, and Cancer Surgery, University of Cologne, Cologne, Germany
    J Surg Res 164:e61-6. 2010
    ..The gene polymorphism of the X-ray-repair-cross complementing (XRCC1-) gene (rs25487) was analyzed to predict response to neoadjuvant radiochemotherapy and prognosis in patients with locally advanced rectal cancer...
  30. ncbi request reprint Effect of "white diet" during bile monitoring with Bilitec 2000 on esophageal pH-metry in patients with gastroesophageal reflux disease
    Christian A Gutschow
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    J Gastrointest Surg 9:508-13. 2005
    ..Data derived from simultaneous esophageal pH and bile monitoring should be interpreted with care...
  31. ncbi request reprint Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer
    Ralf Metzger
    Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Joseph Stelzmann Strasse 9, D 50931 Cologne, Germany
    Anticancer Res 29:1157-62. 2009
    ..The purpose of this study was to evaluate the significance of human telomerase reverse transcriptase (hTERT) mRNA expression and telomerase activity as prognostic markers in non-small cell lung cancer (NSCLC)...
  32. pmc Neoadjuvant chemoradiotherapy for esophageal cancer: impact on extracapsular lymph node involvement
    Ralf Metzger
    Department of General, Visceral and Cancer Surgery, Center for Integrated Oncology, University Hospital of Cologne, Kerpener Strasse 62, Cologne, Germany
    World J Gastroenterol 16:1986-92. 2010
    ..To assess the effects of neoadjuvant chemoradiotherapy (CRT) on the presence of extracapsular lymph node involvement (LNI) and its prognostic value in patients with resected esophageal cancer...
  33. doi request reprint Variable 18F-fluorodeoxyglucose uptake in gastric cancer is associated with different levels of GLUT-1 expression
    Hakan Alakus
    Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Cologne, Germany
    Nucl Med Commun 31:532-8. 2010
    ..To clarify this observation, FDG uptake in gastric carcinoma was analyzed by focusing on histopathology and on the expression of the glucose transporter (GLUT-1) in the primary tumor...
  34. pmc Duodeno-gastric-esophageal reflux--what is pathologic? Comparison of patients with Barrett's esophagus and age-matched volunteers
    Eva Wolfgarten
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    J Gastrointest Surg 11:479-86. 2007
    ..The aim of the study was to analyse pH- and bile-monitoring data in patients with Barrett's esophagus and in age- and gender-matched controls...
  35. ncbi request reprint Frequent down-regulation of pim-1 mRNA expression in non-small cell lung cancer is associated with lymph node metastases
    Ute Warnecke-Eberz
    Department of Visceral and Vascular Surgery, Laboratory for Molecular Oncology, University of Cologne, Kerpener Strasse 62, Cologne, Germany
    Oncol Rep 20:619-24. 2008
    ..8%). Down-regulation occurs already in the early stage of NSCLC and is either directly involved in the lymphatic progression in NSCLC or represents a surrogate marker...
  36. ncbi request reprint Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater
    Klaus L Prenzel
    Department of Visceral and Vascular Surgery, University of Cologne, Joseph Stelzmann Str 9, 50931 Cologne, Germany
    World J Gastroenterol 12:437-42. 2006
    ....
  37. doi request reprint Extracapsular lymph node spread: a new prognostic factor in gastric cancer
    Hakan Alakus
    Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany
    Cancer 116:309-15. 2010
    ..The aim of the current study was to examine the prognostic value of extracapsular lymph node involvement in gastric cancer and to find correlations with clinicopathological parameters...
  38. doi request reprint ERCC1 and XRCC1 gene polymorphisms predict response to neoadjuvant radiochemotherapy in esophageal cancer
    Ute Warnecke-Eberz
    Department of General, Visceral, and Cancer Surgery, Center for Integrated Oncology, University Hospital of Cologne, Kerpener Str 62, 50937, Cologne, Germany
    J Gastrointest Surg 13:1411-21. 2009
    ..We examined a panel of selected gene polymorphisms to predict response to neoadjuvant radiochemotherapy (cisplatin, 5-fluorouracil, 36 Gy) in esophageal cancer patients...
  39. doi request reprint Prevalence of dysphagia in patients with gastroesophageal reflux in Germany
    Elfriede Bollschweiler
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Dysphagia 23:172-6. 2008
    ..001). Swallowing problems are common in patients with GERD. Approximately two thirds of patients with long-term and severe reflux symptoms also have dysphagia symptoms. Dysphagia should always be investigated by a physician...
  40. ncbi request reprint High specificity of quantitative excision repair cross-complementing 1 messenger RNA expression for prediction of minor histopathological response to neoadjuvant radiochemotherapy in esophageal cancer
    Ute Warnecke-Eberz
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Clin Cancer Res 10:3794-9. 2004
    ....
  41. ncbi request reprint Up-regulation of survivin mRNA might be a marker for non-invasive detection of non-small cell lung cancer rather than for prognosis
    Ute Warnecke-Eberz
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Anticancer Res 28:1525-9. 2008
    ..To evaluate the prognostic importance of the apoptosis inhibitor survivin for non-small cell lung cancer (NSCLC), a study was performed in 64 patients with R0 resections for NSCLC and histopathological stages I-IIIA...
  42. ncbi request reprint A multimedia tool for the informed consent of patients prior to gastric banding
    Carsten Eggers
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Obesity (Silver Spring) 15:2866-73. 2007
    ..The current study developed and evaluated a multimedia program aimed at obtaining informed consent from obese patients before gastric banding...
  43. ncbi request reprint Differences between biopsy- or specimen-related Laurén and World Health Organization classification in gastric cancer
    Uta Flucke
    Department of Visceral and VascularSurgery, University of Cologne, Joseph Stelzmann Str 9, 50931 Cologne, Germany
    World J Surg 26:137-40. 2002
    ..Since this may have consequences for the surgical strategy, the extent of surgical resection, rebiopsies, and reconfirmation of an intestinal type should be performed at least in those cases with any doubts of this classification...
  44. doi request reprint Prognostic relevance of skip metastases in esophageal cancer
    Klaus L Prenzel
    Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany
    Ann Thorac Surg 90:1662-7. 2010
    ..Little is known about this form of lymphatic spread in esophageal cancer. The aim of this study was to assess nodal skip metastasis and its clinical importance for patients with cancer of the esophagus...
  45. ncbi request reprint Significant overexpression of SPARC/osteonectin mRNA in pancreatic cancer compared to cancer of the papilla of Vater
    Klaus L Prenzel
    Department of Visceral and Vascular Surgery, University of Cologne, 50931 Cologne, Germany
    Oncol Rep 15:1397-401. 2006
    ..In conclusion, SPARC mRNA overexpression is significantly more frequent in CP than CPV and adds further evidence that CP and CPV are biologically different tumor entities...
  46. doi request reprint Significant down-regulation of the plasminogen activator inhibitor 1 mRNA in pancreatic cancer
    Ute Warnecke-Eberz
    Department of Visceral and Vascular Surgery, University of Cologne, Cologne, Germany
    Pancreas 36:173-7. 2008
    ..Expression profiles were compared with paired uninvolved normal tissues to define a possible differential role of these genes in tumorigenesis of both tumor types...
  47. doi request reprint NERD, GERD, and Barrett's esophagus: role of acid and non-acid reflux revisited with combined pH-impedance monitoring
    Christian A Gutschow
    Department of Visceral and Vascular Surgery, University of Cologne, Kerpener Strasse 62, 50962, Cologne, Germany
    Dig Dis Sci 53:3076-81. 2008
    ..With introduction of combined esophageal pH-impedance monitoring, a precise diagnostic test for acid and non-acid reflux is now available...