Maximilian Bockhorn

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. doi request reprint Hepatocellular carcinoma as a coincidental finding in a patient undergoing surgery for focal nodular hyperplasia
    Georgios C Sotiropoulos
    Liver Int 28:578-9. 2008
  2. ncbi request reprint VEGF is important for early liver regeneration after partial hepatectomy
    Maximilian Bockhorn
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Surg Res 138:291-9. 2007
  3. ncbi request reprint Lack of elevated serum carcinoembryonic antigen and calcitonin in medullary thyroid carcinoma
    Maximilian Bockhorn
    Department of General and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Thyroid 14:468-70. 2004
  4. ncbi request reprint Paraganglioma-like medullary thyroid carcinoma: a rare entity
    Maximilian Bockhorn
    Department of General Surgery and Transplantation Surgery, University Hospital Essen, Germany
    Thyroid 15:1363-7. 2005
  5. doi request reprint Survival of patients with synchronous and metachronous colorectal liver metastases--is there a difference?
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122, Essen, Germany
    J Gastrointest Surg 12:1399-405. 2008
  6. doi request reprint Lymphatic invasion predicts survival in patients with early node-negative non-small cell lung cancer
    Michael F Nentwich
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Thorac Cardiovasc Surg 146:781-7. 2013
  7. doi request reprint Multivisceral resections in pancreatic cancer: identification of risk factors
    Christoph M Burdelski
    Department of General, Visceral, and Thoracic Surgery, University Medical Center, Hamburg Eppendorf, Martinistrasse 52, Hamburg, 20246, Germany
    World J Surg 35:2756-63. 2011
  8. ncbi request reprint Concordance of HER2 status in primary tumour and lymph node metastases in patients with esophageal carcinoma
    Alexandra M König
    Department of General, Visceral and Thoracic Surgery, University Medical Centre of Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Anticancer Res 33:4975-82. 2013
  9. doi request reprint Activated leukocyte cell adhesion molecule (CD166)--its prognostic power for colorectal cancer patients
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Germany
    J Surg Res 177:e15-20. 2012
  10. doi request reprint How radical should surgery be for early esophageal cancer?
    Dean Bogoevski
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
    World J Surg 35:1311-20. 2011

Detail Information

Publications45

  1. doi request reprint Hepatocellular carcinoma as a coincidental finding in a patient undergoing surgery for focal nodular hyperplasia
    Georgios C Sotiropoulos
    Liver Int 28:578-9. 2008
  2. ncbi request reprint VEGF is important for early liver regeneration after partial hepatectomy
    Maximilian Bockhorn
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Surg Res 138:291-9. 2007
    ..The aim of the study was to determine the role of Vascular Endothelial Growth Factor (VEGF) on the microvasculature and on angiogenetic gene expression after partial hepatectomy (PH) in the rat model...
  3. ncbi request reprint Lack of elevated serum carcinoembryonic antigen and calcitonin in medullary thyroid carcinoma
    Maximilian Bockhorn
    Department of General and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Thyroid 14:468-70. 2004
    ..The following case concerns a 50-year-old woman with histologically proven MTC, who completely lacked serum elevation of both CT and CEA...
  4. ncbi request reprint Paraganglioma-like medullary thyroid carcinoma: a rare entity
    Maximilian Bockhorn
    Department of General Surgery and Transplantation Surgery, University Hospital Essen, Germany
    Thyroid 15:1363-7. 2005
    ..The following report describes the case of a 58-year-old man with the rare diagnosis of paraganglioma-like MTC...
  5. doi request reprint Survival of patients with synchronous and metachronous colorectal liver metastases--is there a difference?
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122, Essen, Germany
    J Gastrointest Surg 12:1399-405. 2008
    ..The aim of this study was to compare outcomes in patients with synchronous and metachronous colorectal liver metastases, with special emphasis on prognostic determinants...
  6. doi request reprint Lymphatic invasion predicts survival in patients with early node-negative non-small cell lung cancer
    Michael F Nentwich
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Thorac Cardiovasc Surg 146:781-7. 2013
    ..The aim of this study was to assess the influence of lymphatic and vascular invasion on overall survival in patients with surgically resected non-small cell lung cancer (NSCLC) without lymph node and distant metastases...
  7. doi request reprint Multivisceral resections in pancreatic cancer: identification of risk factors
    Christoph M Burdelski
    Department of General, Visceral, and Thoracic Surgery, University Medical Center, Hamburg Eppendorf, Martinistrasse 52, Hamburg, 20246, Germany
    World J Surg 35:2756-63. 2011
    ..There is an assumption that multivisceral resections (MVRs) in patients with a pancreatic malignancy are associated with higher morbidity. The oncologic benefit, however, remains controversial...
  8. ncbi request reprint Concordance of HER2 status in primary tumour and lymph node metastases in patients with esophageal carcinoma
    Alexandra M König
    Department of General, Visceral and Thoracic Surgery, University Medical Centre of Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Anticancer Res 33:4975-82. 2013
    ..The aim of our study was to investigate the significance of the HER2 status in primary esophageal carcinomas and matched lymph node metastases...
  9. doi request reprint Activated leukocyte cell adhesion molecule (CD166)--its prognostic power for colorectal cancer patients
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Germany
    J Surg Res 177:e15-20. 2012
    ..Controversial data exist regarding the prognostic power of ALCAM expression in CRC. Here, we evaluate the expression of ALCAM in a cohort of CRC patients and its usage as a prognostic marker for survival...
  10. doi request reprint How radical should surgery be for early esophageal cancer?
    Dean Bogoevski
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
    World J Surg 35:1311-20. 2011
    ....
  11. ncbi request reprint Erythropoietin treatment improves liver regeneration and survival in rat models of extended liver resection and living donor liver transplantation
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Germany
    Transplantation 86:1578-85. 2008
    ..Therefore, we have investigated the use of erythropoietin (EPO) as an exogenous stimulator of liver regeneration in rat models of liver resection and LDLT...
  12. pmc CXCR7 expression in esophageal cancer
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Transl Med 11:238. 2013
    ..CXCR7 was recently identified as a novel alternate receptor for CXCL12. The aim of this study was to evaluate the prognostic impact of expression of chemokine receptor CXCR7 in patients with esophageal carcinoma (EC)...
  13. doi request reprint ALCAM (CD166) expression and serum levels are markers for poor survival of esophageal cancer patients
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 131:396-405. 2012
    ..In addition, ALCAM expression in a subset of DTC of the bone marrow indicates a potential function in the metastatic cascade of EC...
  14. doi request reprint An attempt at validation of the Seventh edition of the classification by the International Union Against Cancer for esophageal carcinoma
    Matthias Reeh
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Ann Thorac Surg 93:890-6. 2012
    ....
  15. doi request reprint Major liver resections in the elderly-is an aggressive approach justified?
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Int J Colorectal Dis 24:83-6. 2009
    ..The purpose of our study was to evaluate the outcome of major hepatic resections in the elderly population...
  16. doi request reprint Prognostic impact of CXCR4 and CXCR7 expression in pancreatic adenocarcinoma
    Florian Gebauer
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Surg Oncol 104:140-5. 2011
    ..The aim of this study was to evaluate the prognostic impact of the expression of the chemokine receptors CXCR4 and CXCR7 in patients with pancreatic adenocarcinoma (PAC)...
  17. doi request reprint ALCAM (CD166) expression as novel prognostic biomarker for pancreatic neuroendocrine tumor patients
    Michael Tachezy
    Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Surg Res 170:226-32. 2011
    ..The aim of this study was to determine the expression of ALCAM in PNET to learn more about the prevalence and clinical significance of ALCAM expression in PNET...
  18. doi request reprint Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer
    Faik G Uzunoglu
    Department of General, Visceral and Thoracic Surgery, University Medical Centre of Hamburg Eppendorf, Hamburg, Germany
    Ann Surg Oncol 19:2159-68. 2012
    ..Our purpose was to evaluate VEGFR-2 polymorphisms as prognostic markers for tumor recurrence and overall survival (OS) in non-small-cell lung cancer (NSCLC)...
  19. doi request reprint Prognostic impact of intrahepatic lymphatic and microvascular involvement in cases of colorectal liver metastases
    Maximilian Bockhorn
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Int J Colorectal Dis 24:845-50. 2009
    ..The purpose of this study was to evaluate the effect of intrahepatic microvascular and lymphatic infiltration on survival in cases of colorectal liver metastases...
  20. ncbi request reprint Impact of hepatic vein deprivation on liver regeneration and function after major hepatectomy
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Langenbecks Arch Surg 393:527-33. 2008
    ..The impact of venous outflow impairment and its consequences for liver regeneration and function are still a matter of debate...
  21. pmc ALCAM (CD166) expression and serum levels in pancreatic cancer
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 7:e39018. 2012
    ....
  22. doi request reprint Disseminated tumor cells in pancreatic cancer-an independent prognosticator of disease progression and survival
    Katharina E Effenberger
    Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Germany
    Int J Cancer 131:E475-83. 2012
    ..260-4.135). The presence of DTC in bone marrow is a strong and independent prognostic factor of survival in patients with pancreatic cancer. Thus, bone-targeting may be a new future therapeutic option for DTC-positive patients...
  23. ncbi request reprint Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS)
    Maximilian Bockhorn
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Surgery 155:977-88. 2014
    ..This position statement was developed to expedite a consensus on definition and treatment for borderline resectable pancreatic ductal adenocarcinoma (BRPC) that would have worldwide acceptability...
  24. doi request reprint C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
    Faik Güntac Uzunoglu
    Department of General, Visceral and Thoracic Surgery, University Medical Center of Hamburg Eppendorf, Germany
    Lung Cancer 81:123-9. 2013
    ..018, p = 0.021) in NSCLC and especially in SqCC a negative predictor for DFS and OS (p = 0.045, p = 0.041). Genotyping of the CXCR-2 +1208 C >T polymorphism could be a useful tool to identify high-risk SqCC subgroups...
  25. ncbi request reprint The role of surgery in Caroli's disease
    Maximilian Bockhorn
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Am Coll Surg 202:928-32. 2006
    ..Whether conservative or surgical strategies should be preferred is still a matter of debate. The aim of this study was to evaluate the role of surgery in the management of Caroli's disease...
  26. doi request reprint Ultrasonic dissection versus conventional dissection techniques in pancreatic surgery: a randomized multicentre study
    Faik G Uzunoglu
    Department of General, Visceral and Thoracic Surgery, University Medical Centre Hamburg Eppendorf, Martinistrase 52, Hamburg, Germany
    Ann Surg 256:675-9; discussion 679-80. 2012
    ..This prospective randomized multicenter trial was performed to assess the potential benefits of ultrasonic energy dissection compared with conventional dissection techniques in pancreatic surgery...
  27. doi request reprint High surgical morbidity following distal pancreatectomy: still an unsolved problem
    Matthias Reeh
    Department of General, Visceral and Thoracic Surgery, University Medical Centre Hamburg Eppendorf, Martinistrase 52, 20246, Hamburg, Germany
    World J Surg 35:1110-7. 2011
    ..The aim of this study was to identify potential risk factors for surgical morbidity with a focus on the development of pancreatic fistula...
  28. doi request reprint Bypass surgery versus intentionally incomplete resection in palliation of pancreatic cancer: is resection the lesser evil?
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Germany, Martinistrase 52, 20246, Hamburg, Germany
    J Gastrointest Surg 15:829-35. 2011
    ..We investigated in a retrospective analysis whether even tumor resection that was intended to be incomplete might provide a better outcome than conventional palliative procedures...
  29. doi request reprint Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer
    Cenap Güngör
    Department of General, Visceral and Thoracic Surgery, Campus Research, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Cancer Res 71:5009-19. 2011
    ..Taken together, our findings define an important pathway of chemoresistance in PDAC and suggest novel strategies for its clinical attack...
  30. pmc Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung
    Tatyana Kalinina
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg, Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    BMC Cancer 10:295. 2010
    ..Therefore new models are urgently needed to investigate this deadly disease. As a part of this process we have established and characterized a new human pancreatic cancer cell line...
  31. doi request reprint LigaSure™ vs. conventional dissection techniques in pancreatic surgery--a prospective randomised single-centre trial
    Faik Guentac Uzunoglu
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Martinistraße, 52 20246, Hamburg, Germany
    J Gastrointest Surg 17:494-500. 2013
    ..We compared the use of LigaSure with conventional dissection techniques in pancreatic surgery in a prospective randomised single-centre trial (registration number: NCT00850291)...
  32. ncbi request reprint Surgery for advanced and metastatic pancreatic cancer--current state and trends
    Michael F Nentwich
    Department of General, Visceral and Thoracic Surgery, University Medical Center of Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Anticancer Res 32:1999-2002. 2012
    ..This holds true for en-bloc vascular resections, total pancreatectomies, intentional R2 pancreatic resections and synchronous resection of liver metastases. These issues are addressed in this review...
  33. doi request reprint Deregulation of HIF1-alpha and hypoxia-regulated pathways in hepatocellular carcinoma and corresponding non-malignant liver tissue--influence of a modulated host stroma on the prognosis of HCC
    Frank Simon
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Langenbecks Arch Surg 395:395-405. 2010
    ....
  34. ncbi request reprint Vascular endothelial growth factor does not improve liver regeneration and survival after 90% subtotal liver resection
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Hepatol Res 37:353-9. 2007
    ..This indicates that the relevant mechanisms that stimulate liver regeneration after hepatectomy at least partially depend upon the extent of liver resection...
  35. ncbi request reprint Activated leukocyte cell adhesion molecule (CD166): an "inert" cancer stem cell marker for non-small cell lung cancer?
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Stem Cells 32:1429-36. 2014
    ..The association of CD166 with smaller tumors and no nodal metastases does not make it a typical CSC marker. Further studies are required to investigate the functional role of CD166 in NSCLC...
  36. doi request reprint Long-term results of primary and secondary resections in patients with retroperitoneal soft tissue sarcoma
    Alexandra M Koenig
    Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
    Langenbecks Arch Surg 397:1251-9. 2012
    ..The aim of this study was to analyse treatment and long-term outcome for primary and recurrent disease in patients with retroperitoneal soft tissue sarcoma (RSTS)...
  37. pmc Impact of early or delayed elective resection in complicated diverticulitis
    Kai Bachmann
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    World J Gastroenterol 17:5274-9. 2011
    ..To investigate the outcomes of early and delayed elective resection after initial antibiotic treatment in patients with complicated diverticulitis...
  38. ncbi request reprint Liver transplantation for hepatocellular carcinoma and cirrhosis in candidates with undetectable or very low alpha-fetoprotein levels: is an expansion of the listing criteria justified?
    Georgios C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 55:1671-7. 2008
    ..The purpose of this study was to evaluate the results after LT for HCC patients with very low alpha fetoprotein (AFP) values both in our series and in literature reports...
  39. doi request reprint Chronic pancreatitis complicated by cavernous transformation of the portal vein: contraindication to surgery?
    Maximilian Bockhorn
    Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Germany
    Surgery 149:321-8. 2011
    ..The purpose of this study was to address the question of whether a noninterventional approach regarding surgery is justified...
  40. pmc Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749)
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistr, 52, Hamburg 20246, Germany
    BMC Cancer 14:411. 2014
    ..However, controlled, randomized trials addressing the impact of neoadjuvant CRT survival do not exist...
  41. doi request reprint Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus
    Tatyana Kalinina
    Department of General, Visceral and Thoracic Surgery, University Medical Center, Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 127:1931-40. 2010
    ..IGF-1R expression can be used as a novel prognostic marker for adenocarcinomas of the esophagus. Cotreatment with IGF-1R and HER2 antibodies might become a valuable and effective treatment option in esophageal adenocarcinoma...
  42. pmc Circulating levels of cell adhesion molecule L1 as a prognostic marker in gastrointestinal stromal tumor patients
    Hilke Zander
    Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    BMC Cancer 11:189:1-7. 2011
    ..The aim of the current study was to compare L1 serum levels of GIST patients with those of healthy controls and to determine whether levels of soluble L1 in sera could serve as a prognostic marker...
  43. ncbi request reprint RET proto-oncogene mutations affecting codon 790/791: A mild form of multiple endocrine neoplasia type 2A syndrome?
    Oliver Gimm
    Department of General, Visceral, and Vascular Surgery, Martin Luther University Halle Wittenberg, Ernst Grube Strasse 40, 06097 Halle, Germany
    Surgery 132:952-9; discussion 959. 2002
    ..In patients with multiple endocrine neoplasia type 2A syndrome, prophylactic thyroidectomy is generally recommended at the age of 5 to 6 years. Whether this recommendation is justified for exon 13 mutations is unknown...
  44. doi request reprint Extended central pancreatic resection as an alternative for extended left or extended right resection for appropriate pancreatic neoplasms
    Guellue Cataldegirmen
    Department of General, Viszeral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Surgery 147:331-8. 2010
    ....
  45. ncbi request reprint Differential vascular and transcriptional responses to anti-vascular endothelial growth factor antibody in orthotopic human pancreatic cancer xenografts
    Maximilian Bockhorn
    Department of Radiation Oncology, Edwin L Steele Laboratory, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA
    Clin Cancer Res 9:4221-6. 2003
    ....