Lars M Blank
Affiliation: University of Dortmund
- Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeastLars M Blank
Institute of Biotechnology, ETH Zurich, 8093 Zurich, Switzerland
Genome Biol 6:R49. 2005..Here we identify key experiments in a systems biology approach with a genome-scale model of Saccharomyces cerevisiae metabolism, thereby reducing the workload for experimental network analyses and functional genomics...
- Metabolic-flux and network analysis in fourteen hemiascomycetous yeastsLars M Blank
Institute of Biotechnology, Building HPT E58, ETH Zurich, 8093 Zurich, Switzerland
FEMS Yeast Res 5:545-58. 2005..In most yeasts, the PP pathway activity appears to be driven exclusively by the demand for NADPH...
- Metabolic functions of duplicate genes in Saccharomyces cerevisiaeLars Kuepfer
Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland
Genome Res 15:1421-30. 2005..Thus, at least for metabolism, persistence of the paralog fraction in the genome can be better explained with an array of different, often overlapping functional roles...
- TCA cycle activity in Saccharomyces cerevisiae is a function of the environmentally determined specific growth and glucose uptake ratesLars M Blank
Institute of Biotechnology, ETH Zurich, Zurich, Switzerland
Microbiology 150:1085-93. 2004..While sensing of extracellular glucose concentrations has a general influence on the in vivo TCA cycle activity, the growth-rate-dependent increase in respiratory TCA cycle activity was independent of glucose sensing...