Lars M Blank

Summary

Affiliation: University of Dortmund
Country: Germany

Publications

  1. ncbi Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast
    Lars M Blank
    Institute of Biotechnology, ETH Zurich, 8093 Zurich, Switzerland
    Genome Biol 6:R49. 2005
  2. ncbi Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts
    Lars M Blank
    Institute of Biotechnology, Building HPT E58, ETH Zurich, 8093 Zurich, Switzerland
    FEMS Yeast Res 5:545-58. 2005
  3. ncbi Metabolic functions of duplicate genes in Saccharomyces cerevisiae
    Lars Kuepfer
    Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland
    Genome Res 15:1421-30. 2005
  4. ncbi TCA cycle activity in Saccharomyces cerevisiae is a function of the environmentally determined specific growth and glucose uptake rates
    Lars M Blank
    Institute of Biotechnology, ETH Zurich, Zurich, Switzerland
    Microbiology 150:1085-93. 2004

Collaborators

  • Lars Kuepfer
  • Uwe Sauer

Detail Information

Publications4

  1. ncbi Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast
    Lars M Blank
    Institute of Biotechnology, ETH Zurich, 8093 Zurich, Switzerland
    Genome Biol 6:R49. 2005
    ..Here we identify key experiments in a systems biology approach with a genome-scale model of Saccharomyces cerevisiae metabolism, thereby reducing the workload for experimental network analyses and functional genomics...
  2. ncbi Metabolic-flux and network analysis in fourteen hemiascomycetous yeasts
    Lars M Blank
    Institute of Biotechnology, Building HPT E58, ETH Zurich, 8093 Zurich, Switzerland
    FEMS Yeast Res 5:545-58. 2005
    ..In most yeasts, the PP pathway activity appears to be driven exclusively by the demand for NADPH...
  3. ncbi Metabolic functions of duplicate genes in Saccharomyces cerevisiae
    Lars Kuepfer
    Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland
    Genome Res 15:1421-30. 2005
    ..Thus, at least for metabolism, persistence of the paralog fraction in the genome can be better explained with an array of different, often overlapping functional roles...
  4. ncbi TCA cycle activity in Saccharomyces cerevisiae is a function of the environmentally determined specific growth and glucose uptake rates
    Lars M Blank
    Institute of Biotechnology, ETH Zurich, Zurich, Switzerland
    Microbiology 150:1085-93. 2004
    ..While sensing of extracellular glucose concentrations has a general influence on the in vivo TCA cycle activity, the growth-rate-dependent increase in respiratory TCA cycle activity was independent of glucose sensing...