Arijit Biswas

Summary

Affiliation: Institute of Experimental Hematology and Transfusion Medicine
Location: Bonn, Germany
URL: http://www.ukb.uni-bonn.de/quick2web/internet/internet.nsf/04fa7deb65dc84f9c1256a6200552c10/787f24ed3fdedf48c12577f40046fa2c?OpenDocument
Summary:
Research on Factor XIII deficiency and structure functional relationships of Factor XIII
Publications:
1: Ivaskevicius V, Biswas A, Bevans C, Schroeder V, Kohler HP, Rott H, Halimeh S,
Petrides PE, Lenk H, Krause M, Miterski B, Harbrecht U, Oldenburg J.
Identification of eight novel coagulation factor XIII subunit A mutations:
implied consequences for structure and function. Haematologica. 2010
Jun;95(6):956-62. Epub 2010 Feb 23. PubMed PMID: ; PubMed Central PMCID:
PMC2878794.


2: Ivaskevicius V, Biswas A, Loreth R, Schroeder V, Ohlenforst S, Rott H, Krause
M, Kohler HP, Scharrer I, Oldenburg J. Mutations affecting disulphide bonds
contribute to a fairly common prevalence of F13B gene defects: results of a
genetic study in 14 families with factor XIII B deficiency. Haemophilia. 2010 Jul
1;16(4):675-82. Epub 2010 Mar 10. PubMed PMID: .


3: Biswas A, Ivaskevicius V, Seitz R, Thomas A, Oldenburg J. An update of the
mutation profile of Factor 13 A and B genes. Blood Rev. 2011 Sep;25(5):193-204.
Epub 2011 Jun 2. PubMed PMID: .

Publications

  1. Biswas A, Ivaskevicius V, Seitz R, Thomas A, Oldenburg J. An update of the mutation profile of Factor 13 A and B genes. Blood Rev. 2011;25:193-204 pubmed publisher
    ..The source of our mutational data is our website dedicated to Factor XIII deficiencies (www.F13-database.de) as well as literature search done on the Pubmed (www.ncbi.nlm.nih.gov/pubmed). ..
  2. Ivaskevicius V, Biswas A, Bevans C, Schroeder V, Kohler H, Rott H, et al. Identification of eight novel coagulation factor XIII subunit A mutations: implied consequences for structure and function. Haematologica. 2010;95:956-62 pubmed publisher
    ..Future in vitro expression studies of the factor XIII mutations are required to confirm their pathological mechanisms. ..
  3. Ivaskevicius V, Biswas A, Loreth R, Schroeder V, Ohlenforst S, Rott H, et al. Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency. Haemophilia. 2010;16:675-82 pubmed publisher
    ..The present study reports on a fairly common prevalence of F13B gene defects in the German population. The regions in and around the cysteine disulphide bonds in the FXIII-B protein may be regions prone to frequent mutations. ..
  4. Biswas A, Ivaskevicius V, Thomas A, Oldenburg J. Coagulation factor XIII deficiency. Diagnosis, prevalence and management of inherited and acquired forms. Hamostaseologie. 2014;34:160-6 pubmed publisher
    ..Here, we update the knowledge about the pathophysiology of factor XIII deficiency and its therapeutic options. ..
  5. Thomas A, Biswas A, Dodt J, Philippou H, Hethershaw E, Ensikat H, et al. Coagulation Factor XIIIA Subunit Missense Mutations Affect Structure and Function at the Various Steps of Factor XIII Action. Hum Mutat. 2016;37:1030-41 pubmed publisher
    ..We identified mutations which even in heterozygous form would have strong impact on the functional status of the protein (namely mutations p.Arg716Gly, p.Arg704Gln, p.Gln602Lys, p.Leu530Pro, p.His343Tyr, p.Pro290Arg, and p.Arg172Gln). ..

Detail Information

Publications5