Ulrike Bingel

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Single trial fMRI reveals significant contralateral bias in responses to laser pain within thalamus and somatosensory cortices
    U Bingel
    Department of Neurology, Hamburg University Medical School, Hamburg, Germany
    Neuroimage 18:740-8. 2003
  2. doi request reprint Neuroimaging as a tool to investigate how cognitive factors influence analgesic drug outcomes
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurosci Lett 520:149-55. 2012
  3. ncbi request reprint fMRI reveals how pain modulates visual object processing in the ventral visual stream
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Neuron 55:157-67. 2007
  4. pmc Mechanisms and clinical implications of the placebo effect: is there a potential for the elderly? A mini-review
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Gerontology 57:354-63. 2011
  5. doi request reprint [Migraine and hormones: what can we be certain of?]
    U Bingel
    Klinik und Poliklinik fur Neurologie, Universitäts Klinkum Hamburg Eppendorf UKE, Martinistr 52, 20246, Hamburg, Germany
    Schmerz 22:31-6. 2008
  6. ncbi request reprint Imaging pain modulation in health and disease
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Curr Opin Neurol 20:424-31. 2007
  7. ncbi request reprint Habituation to painful stimulation involves the antinociceptive system
    U Bingel
    Department of Neurology, University of Hamburg UKE, Germany
    Pain 131:21-30. 2007
  8. ncbi request reprint [Headache as a warning symptom]
    Ulrike Bingel
    Neurologische Klinik und Poliklinik, Universitäts Krankenhaus Hamburg Eppendorf
    MMW Fortschr Med 148:47, 49-50. 2006
  9. ncbi request reprint Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network
    U Bingel
    NeuroImage Nord, Institute for Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
    Pain 120:8-15. 2006
  10. ncbi request reprint An unusual indomethacin-sensitive headache: a case of bilateral episodic paroxysmal hemicrania without autonomic symptoms?
    U Bingel
    Department of Neurology, Hamburg University Medical School, Hamburg, Germany
    Cephalalgia 25:148-50. 2005

Detail Information

Publications34

  1. ncbi request reprint Single trial fMRI reveals significant contralateral bias in responses to laser pain within thalamus and somatosensory cortices
    U Bingel
    Department of Neurology, Hamburg University Medical School, Hamburg, Germany
    Neuroimage 18:740-8. 2003
    ....
  2. doi request reprint Neuroimaging as a tool to investigate how cognitive factors influence analgesic drug outcomes
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurosci Lett 520:149-55. 2012
    ..Taking pain as an example, we portrait recent advances in this field and discuss basic science and clinical implications...
  3. ncbi request reprint fMRI reveals how pain modulates visual object processing in the ventral visual stream
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Neuron 55:157-67. 2007
    ....
  4. pmc Mechanisms and clinical implications of the placebo effect: is there a potential for the elderly? A mini-review
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Gerontology 57:354-63. 2011
    ..Even though a systematic knowledge of placebo effects across the lifespan is lacking, we aim at highlighting specific aspects related to the care of elderly patients and those suffering from neurodegenerative diseases...
  5. doi request reprint [Migraine and hormones: what can we be certain of?]
    U Bingel
    Klinik und Poliklinik fur Neurologie, Universitäts Klinkum Hamburg Eppendorf UKE, Martinistr 52, 20246, Hamburg, Germany
    Schmerz 22:31-6. 2008
    ..In summary, epidemiological, clinical and experimental studies document a substantial influence of female sex hormones on the pathophysiology of migraine headache...
  6. ncbi request reprint Imaging pain modulation in health and disease
    Ulrike Bingel
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Curr Opin Neurol 20:424-31. 2007
    ..We focus on the involvement of endogenous pain control mechanisms in the healthy central nervous system and the potential contribution of failure within this system for chronic pain states...
  7. ncbi request reprint Habituation to painful stimulation involves the antinociceptive system
    U Bingel
    Department of Neurology, University of Hamburg UKE, Germany
    Pain 131:21-30. 2007
    ..Given this area's predominant role in endogenous pain control, this response pattern suggests that habituation to pain is at least in part mediated by increased antinociceptive activity...
  8. ncbi request reprint [Headache as a warning symptom]
    Ulrike Bingel
    Neurologische Klinik und Poliklinik, Universitäts Krankenhaus Hamburg Eppendorf
    MMW Fortschr Med 148:47, 49-50. 2006
  9. ncbi request reprint Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network
    U Bingel
    NeuroImage Nord, Institute for Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
    Pain 120:8-15. 2006
    ..This finding supports the view that placebo analgesia depends on the enhanced functional connectivity of the rACC with subcortical brain structures that are crucial for conditioned learning and descending inhibition of nociception...
  10. ncbi request reprint An unusual indomethacin-sensitive headache: a case of bilateral episodic paroxysmal hemicrania without autonomic symptoms?
    U Bingel
    Department of Neurology, Hamburg University Medical School, Hamburg, Germany
    Cephalalgia 25:148-50. 2005
  11. ncbi request reprint Somatotopic organization of human somatosensory cortices for pain: a single trial fMRI study
    U Bingel
    Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany
    Neuroimage 23:224-32. 2004
    ....
  12. ncbi request reprint Somatotopic representation of nociceptive information in the putamen: an event-related fMRI study
    U Bingel
    NeuroImage Nord, Department of Neurology, Hamburg University Medical School, Germany
    Cereb Cortex 14:1340-5. 2004
    ....
  13. doi request reprint [Mechanisms of endogenous pain modulation illustrated by placebo analgesia : functional imaging findings]
    U Bingel
    Klinik und Poliklinik fur Neurologie, Universitäts Klinikum Hamburg Eppendorf UKE, Martinistr 52, 20246, Hamburg, Deutschland
    Schmerz 24:122-9. 2010
    ..Here we discuss recent advances in pain imaging research focusing on cognitively triggered endogenous pain control mechanisms and respective implications for future research strategies...
  14. ncbi request reprint Direct evidence for spinal cord involvement in placebo analgesia
    Falk Eippert
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Science 326:404. 2009
    ..These results provide direct evidence for spinal inhibition as one mechanism of placebo analgesia and highlight that psychological factors can act on the earliest stages of pain processing in the central nervous system...
  15. doi request reprint Attention modulates spinal cord responses to pain
    Christian Sprenger
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Curr Biol 22:1019-22. 2012
    ..Taken together, our results show that the reduced pain experience during mental distraction is related to a spinal process and involves opioid neurotransmission...
  16. pmc The effect of opioid receptor blockade on the neural processing of thermal stimuli
    Eszter D Schoell
    NeuroImage Nord, Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 5:e12344. 2010
    ..On the neural level, painful thermal stimulation was associated with a negative BOLD signal within the pregenual anterior cingulate cortex, and this deactivation was abolished by naloxone...
  17. doi request reprint Activation of the opioidergic descending pain control system underlies placebo analgesia
    Falk Eippert
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Neuron 63:533-43. 2009
    ..These findings show that opioidergic signaling in pain-modulating areas and the projections to downstream effectors of the descending pain control system are crucially important for placebo analgesia...
  18. doi request reprint Pain-specific modulation of hippocampal activity and functional connectivity during visual encoding
    Katarina Forkmann
    Department of Neurology, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    J Neurosci 33:2571-81. 2013
    ..In summary, our results show a pain-related disruption of visual encoding over and above the unpleasantness of a stimulus, suggesting a pain-specific interruptive mechanism that interferes with an early stage of memory formation...
  19. ncbi request reprint Representation of spatial information in key areas of the descending pain modulatory system
    Christoph Ritter
    Department of Neurology, University Hospital Essen, University Duisburg Essen, 45147 Essen, Germany, and Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany and German Center for Neurodegenerative Diseases, 39120 Magdeburg, Germany
    J Neurosci 34:4634-9. 2014
    ....
  20. doi request reprint White matter integrity of the descending pain modulatory system is associated with interindividual differences in placebo analgesia
    Niklas Stein
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
    Pain 153:2210-7. 2012
    ..Our findings provide the first evidence that the white matter integrity within and between regions of the descending pain modulatory network is critically linked with the individual ability for endogenous pain control...
  21. doi request reprint Blockade of endogenous opioid neurotransmission enhances acquisition of conditioned fear in humans
    Falk Eippert
    Departments of Systems Neuroscience and Neurology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    J Neurosci 28:5465-72. 2008
    ..Together, these results demonstrate that in humans the endogenous opioid system has an inhibitory role in the acquisition of fear...
  22. ncbi request reprint Imaging CNS modulation of pain in humans
    Ulrike Bingel
    Department of Neurology, NeuroImage Nord, University Medical Center Hamburg Eppendorf, Germany
    Physiology (Bethesda) 23:371-80. 2008
    ..Research on the involved circuitry and implemented mechanisms is a major focus of contemporary neuroscientific research in the field of pain and should provide new insights to prevent and treat chronic pain states...
  23. doi request reprint Treating pain with pain: supraspinal mechanisms of endogenous analgesia elicited by heterotopic noxious conditioning stimulation
    Christian Sprenger
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Pain 152:428-39. 2011
    ..Functional magnetic resonance imaging shows how the human brain is involved in heterotopic noxious conditioning and reveals active supraspinal pain modulatory mechanisms during dual pain stimulation...
  24. doi request reprint Severe glycerol intoxication after Menière's disease diagnostic--case report and overview of kinetic data
    Hilke Andresen
    Toxicology Unit, Department of Legal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Toxicol (Phila) 47:312-6. 2009
    ..The test procedure starts with oral administration of glycerol, the maximal dose should not exceed 1.5 g/kg of body weight...
  25. doi request reprint Habituation to pain: further support for a central component
    C Rennefeld
    Department of Neurology, University of Hamburg UKE, Germany
    Pain 148:503-8. 2010
    ..Taken together, these results strongly support the role of central components in the mechanism of pain habituation that do not directly involve the endogenous opioid system...
  26. pmc Ventral striatal activity correlates with memory confidence for old- and new-responses in a difficult recognition test
    Ulrike Schwarze
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 8:e54324. 2013
    ..Taken together, the results are in line with the hypothesis that ventral striatal activity during recognition codes the subjective value of different response types that is modulated by the context of the recognition test...
  27. ncbi request reprint Common neural systems for contact heat and laser pain stimulation reveal higher-level pain processing
    Christoph Helmchen
    NeuroImage Nord, Department of Neurology, University of Lubeck, Germany
    Hum Brain Mapp 29:1080-91. 2008
    ..These similarities are likely to reflect higher-level pain processing, which is largely independent of the single physical parameters that determine the painful nature of the stimuli...
  28. ncbi request reprint Subcortical structures involved in pain processing: evidence from single-trial fMRI
    U Bingel
    Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Hamburg, Germany
    Pain 99:313-21. 2002
    ..e. asymmetric) responses according to the side of stimulation. This suggests that spatial information about the nociceptive stimulus is made available in these structures for the guidance of defensive and withdrawal behavior...
  29. pmc Age-dependent decline of endogenous pain control: exploring the effect of expectation and depression
    Wiebke Grashorn
    Department of Neurology, University Medical Center Hamburg Eppendorf UKE, Hamburg, Germany
    PLoS ONE 8:e75629. 2013
    ..Furthermore, changes in CPM responses did not differ between men and women. Our results strongly support the notion of a genuine deterioration of descending pain inhibitory mechanisms with age. ..
  30. doi request reprint Event-related nociceptive arousal enhances memory consolidation for neutral scenes
    Ulrike Schwarze
    Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    J Neurosci 32:1481-7. 2012
    ..Moreover, successful memory formation for stimuli followed by arousal was correlated with activity in the parahippocampal cortex but not the amygdala, as is the case for emotional stimuli...
  31. ncbi request reprint Cortical activation in patients with functional hemispherectomy
    G Leonhardt
    Department of Neurology, University of Essen, Germany
    J Neurol 248:881-8. 2001
    ....
  32. doi request reprint The importance of placebo in headache research
    H C Diener
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Cephalalgia 28:1003-11. 2008
    ..Variables known to influence the placebo response have to be taken into consideration to calculate properly the power of planned randomized trials...
  33. ncbi request reprint Neuroimaging the genomics of pain processing--a perspective
    C Ritter
    Department of Neurology, Christian Albrechts University Kiel, Germany
    Neuroscience 164:141-55. 2009
    ..This review presents the pioneering endeavors of the hybrid approach of neuroimaging pain genes in humans and identifies potential future directions...
  34. doi request reprint Changes in brain gray matter due to repetitive painful stimulation
    S Teutsch
    Department of Systems Neuroscience, University of Hamburg UKE, D 20246 Hamburg, Germany
    Neuroimage 42:845-9. 2008
    ..e. they recede after the regular nociceptive input is stopped. This data raises some interesting questions regarding structural plasticity of the brain concerning the experience of both acute and chronic pain...