Hans-Konrad Biesalski

Summary

Affiliation: University of Hohenheim
Country: Germany

Publications

  1. ncbi request reprint The importance of beta-carotene as a source of vitamin A with special regard to pregnant and breastfeeding women
    Manuela Strobel
    Nutrition and Food Security, Gronau, Germany
    Eur J Nutr 46:I1-20. 2007
  2. pmc Infant feeding practices among mildly wasted children: a retrospective study on Nias Island, Indonesia
    Dyah Ayu Inayati
    Institute for Social Sciences in Agriculture, Center Gender and Nutrition 430b, University Hohenheim, Fruwirthstrasse 14 16, 70593 Stuttgart, Germany
    Int Breastfeed J 7:3. 2012
  3. doi request reprint Vitamin D recommendations: beyond deficiency
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, Food Security Center, University of Hohenheim, Stuttgart, Germany
    Ann Nutr Metab 59:10-6. 2011
  4. pmc Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials
    Hans K Biesalski
    Department of Biological Chemistry and Nutritional Science, University of Hohenheim, Garbenstrasse 28, D 70593 Stuttgart, Germany
    Nutrients 2:929-49. 2010
  5. ncbi request reprint Diabetes preventive components in the Mediterranean diet
    Hans K Biesalski
    Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstrasse 12, 70593 Stuttgart, Germany
    Eur J Nutr 43:I/26-30. 2004
  6. ncbi request reprint New aspects in vitamin a metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epithelia
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, FRG
    J Nutr 134:3453S-3457S. 2004
  7. ncbi request reprint The significance of vitamin A for the development and function of the lung
    H K Biesalski
    University of Hohenheim, Institute 140, Stuttgart, Germany
    Forum Nutr 56:37-40. 2003
  8. ncbi request reprint Nutritargeting
    H K Biesalski
    University of Hohenheim, Institute 140, Stuttgart, Germany
    Forum Nutr 56:200-2. 2003
  9. ncbi request reprint Antioxidant therapy in critical care--is the microcirculation the primary target?
    Hans Konrad Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Germany
    Crit Care Med 35:S577-83. 2007
  10. ncbi request reprint Polyphenols and inflammation: basic interactions
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
    Curr Opin Clin Nutr Metab Care 10:724-8. 2007

Collaborators

Detail Information

Publications39

  1. ncbi request reprint The importance of beta-carotene as a source of vitamin A with special regard to pregnant and breastfeeding women
    Manuela Strobel
    Nutrition and Food Security, Gronau, Germany
    Eur J Nutr 46:I1-20. 2007
    ..For them, recommendations to be aware of potential nutrient intake inadequacies might prove useful...
  2. pmc Infant feeding practices among mildly wasted children: a retrospective study on Nias Island, Indonesia
    Dyah Ayu Inayati
    Institute for Social Sciences in Agriculture, Center Gender and Nutrition 430b, University Hohenheim, Fruwirthstrasse 14 16, 70593 Stuttgart, Germany
    Int Breastfeed J 7:3. 2012
    ..abstract:..
  3. doi request reprint Vitamin D recommendations: beyond deficiency
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, Food Security Center, University of Hohenheim, Stuttgart, Germany
    Ann Nutr Metab 59:10-6. 2011
    ..Consequently, it should be strongly recommended to increase the intake of vitamin D and to ensure a daily intake of vitamin A as counseled...
  4. pmc Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials
    Hans K Biesalski
    Department of Biological Chemistry and Nutritional Science, University of Hohenheim, Garbenstrasse 28, D 70593 Stuttgart, Germany
    Nutrients 2:929-49. 2010
    ..These results suggest that analyses of potential risks from antioxidant supplementation should be placed in the context of a benefit/risk ratio...
  5. ncbi request reprint Diabetes preventive components in the Mediterranean diet
    Hans K Biesalski
    Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstrasse 12, 70593 Stuttgart, Germany
    Eur J Nutr 43:I/26-30. 2004
    ..Based on recent studies from the nurses health and physicians health study, a diet which is similar to the Mediterranean diet, physical exercise and a BMI < 25 protects from the development of diabetes type 2...
  6. ncbi request reprint New aspects in vitamin a metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epithelia
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, FRG
    J Nutr 134:3453S-3457S. 2004
    ..In conclusion, topically applied retinyl esters may be a promising therapy for local retinol deficiencies and may reverse the morphological alterations of the epithelium in tissues that are vitamin A deficient...
  7. ncbi request reprint The significance of vitamin A for the development and function of the lung
    H K Biesalski
    University of Hohenheim, Institute 140, Stuttgart, Germany
    Forum Nutr 56:37-40. 2003
  8. ncbi request reprint Nutritargeting
    H K Biesalski
    University of Hohenheim, Institute 140, Stuttgart, Germany
    Forum Nutr 56:200-2. 2003
  9. ncbi request reprint Antioxidant therapy in critical care--is the microcirculation the primary target?
    Hans Konrad Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Germany
    Crit Care Med 35:S577-83. 2007
    ..Therefore, a significant body of pharmacologic evidence and sound preliminary clinical evidence supports the biological feasibility of using the exemplary antioxidant, vitamin C, in the treatment of the critically ill...
  10. ncbi request reprint Polyphenols and inflammation: basic interactions
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
    Curr Opin Clin Nutr Metab Care 10:724-8. 2007
    ..This review summarizes recent papers dealing with the effect of polyphenols on modulators of the inflammatory cascade...
  11. doi request reprint Parenteral ascorbic acid in haemodialysis patients
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Curr Opin Clin Nutr Metab Care 11:741-6. 2008
    ..The review summarizes recent findings of the effects of parenteral ascorbic acid and discusses toxicological effects...
  12. doi request reprint Bioactive compounds: safety and efficacy
    Hans Konrad Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Nutrition 25:1206-11. 2009
    ....
  13. doi request reprint Bioactive compounds: definition and assessment of activity
    Hans Konrad Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Nutrition 25:1202-5. 2009
    ..The explicatory text accompanying the short answers was produced and agreed on after the conference and was backed up by corresponding references...
  14. doi request reprint Vitamin E requirements in parenteral nutrition
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Gastroenterology 137:S92-104. 2009
    ..Randomized clinical trials are performed using special formulations of vitamin E solutions because vitamin E is available only in lipid emulsions to protect lipids, but not in an isolated solution for parenteral supply...
  15. doi request reprint 26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: evidence-based nutrition
    Hans Konrad Biesalski
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Nutrition 27:S1-20. 2011
    ..The objective was to define the term evidence based nutrition on the basis of expert discussions and scientific evidence...
  16. ncbi request reprint Hohenheimer Consensus Talk. Oxidative and premature skin ageing
    H K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstr 12, 70593 Stuttgart, Germany
    Exp Dermatol 12:3-15. 2003
    ..There was a special focus on prevention and intervention of skin ageing with nutrition. Finally, the paper summarizes the scientific background from different areas related to oxidative and premature skin ageing...
  17. ncbi request reprint Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein
    H K Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
    Am J Clin Nutr 69:931-6. 1999
    ..In addition, other factors associated with low retinol concentrations (eg, low plasma transthyretin or zinc concentrations or mutations in the transthyretin gene) were not present. Neither sibling had a history of systemic disease...
  18. ncbi request reprint Retinyl palmitate supplementation by inhalation of an aerosol improves vitamin A status of preschool children in Gondar (Ethiopia)
    H Biesalski
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Br J Nutr 82:179-82. 1999
    ..01) and 97.3 (SD 31.2) mg/l (P < 0.05) 3 months after supplementation with retinyl palmitate, suggesting that this novel method of delivery of retinyl palmitate by inhalation is effective in improving vitamin A status...
  19. ncbi request reprint Photoprotection of UV-irradiated human skin: an antioxidative combination of vitamins E and C, carotenoids, selenium and proanthocyanidins
    Anne Katrin Greul
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Skin Pharmacol Appl Skin Physiol 15:307-15. 2002
    ..This might be important for future recommendations for immediate suppression of the early phase of UV-induced erythema, that means pharmacological prevention of sunburn reaction as well as subsequent chronic skin damage...
  20. ncbi request reprint UV light, beta-carotene and human skin--beneficial and potentially harmful effects
    H K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Arch Biochem Biophys 389:1-6. 2001
    ..At present, there is an ongoing debate on the protective or potentially harmful role of beta-carotene in human skin...
  21. ncbi request reprint Topical application of vitamin A reverses metaplasia of rat vaginal epithelium: a rapid and efficient approach to improve mucosal barrier function
    H K Biesalski
    University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstr 12, D 70593 Stuttgart, Germany
    Eur J Med Res 6:391-8. 2001
    ..025) increase in the protection time. These data demonstrate that squamous changes induced by vitamin A deficiency can be totally reversed with topically applied retinyl palmitate...
  22. ncbi request reprint Free radical theory of aging
    Hans K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, D 70593 Stuttgart, Germany
    Curr Opin Clin Nutr Metab Care 5:5-10. 2002
    ....
  23. ncbi request reprint Meat and cancer: meat as a component of a healthy diet
    H K Biesalski
    Department of Biological Chemistry and Nutrition, University Hohenheim, Stuttgart, Germany
    Eur J Clin Nutr 56:S2-11. 2002
    ..The latter can be optimized by a diet containing fruit and vegetables, which contain hundreds of more or less proven bioactive constituents, many of them showing antioxidative and anticarcinogenic effects in vitro...
  24. ncbi request reprint Lycopene inhibits disease progression in patients with benign prostate hyperplasia
    Silke Schwarz
    University of Hohenheim, Institute of Biological Chemistry and Nutrition, 70593 Stuttgart, Germany
    J Nutr 138:49-53. 2008
    ..In conclusion, lycopene inhibited progression of BPH...
  25. ncbi request reprint Importance of vitamin-A for lung function and development
    H K Biesalski
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstr 12, Stuttgart D 70593, Germany
    Mol Aspects Med 24:431-40. 2003
    ....
  26. ncbi request reprint The effect of beta-carotene on the expression of interleukin-6 and heme oxygenase-1 in UV-irradiated human skin fibroblasts in vitro
    U C Obermüller-Jevic
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Fruwirthstrasse 12, 70593, Stuttgart, Germany
    FEBS Lett 509:186-90. 2001
    ..In UVB-irradiated cells, beta-carotene did not modulate levels of IL-6 and HO-1. The observed effects might be relevant for UV-induced inflammatory processes...
  27. ncbi request reprint [Antioxidants - no reason for a reassessment]
    H K Biesalski
    Institut fur Biologische Chemie und Ernahrungswissenschaft, Garbenstrasse 30, 70593 Stuttgart, Deutschland
    Ophthalmologe 104:618-9. 2007
  28. ncbi request reprint Long-term sequelae of HFE deletion in C57BL/6 x 129/O1a mice, an animal model for hereditary haemochromatosis
    A Lebeau
    Pathologisches Institut, Ludwig Maximilians Universitat, Munchen, Germany, Universitat Hohenheim, Stuttgart, Germany
    Eur J Clin Invest 32:603-12. 2002
    ..HFE knockout mice (C57BL/6 x 129/Ola strain) mimic the functional aberrations of human hereditary haemochromatosis (HH) in short-term experiments. The present study investigates functional and morphological long-term changes...
  29. ncbi request reprint Uptake of vitamin A in buccal mucosal cells after topical application of retinyl palmitate: a randomised, placebo-controlled and double-blind trial
    U Sobeck
    University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstrasse 12, D 70593 Stuttgart, Germany
    Br J Nutr 90:69-74. 2003
    ..05) increase of plasma retinol after 17 d was demonstrated in our present study. The uptake of retinyl palmitate and the following hydrolysis to retinol led to an enrichment of vitamin A in buccal mucosal cells...
  30. ncbi request reprint [Antioxidants--helpful or harmful?]
    H K Biesalski
    Institut fur Biologische Chemie und Ernahrungswissenschaft, Universitat Hohenheim, Stuttgart, Germany
    Ther Umsch 64:135-9. 2007
    ..Whether the consumer may have a benefit from fortified food has not yet been evaluated with respect to antioxidant vitamins...
  31. ncbi request reprint Relation of DDT residues to plasma retinol, alpha-tocopherol, and beta-carotene during pregnancy and malaria infection: a case-control study in Karen women in northern Thailand
    W Stuetz
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, 70599 Stuttgart, Germany
    Sci Total Environ 363:78-86. 2006
    ..51, p<0.001). Plasma alpha-tocopherol and beta-carotene seemed not to be affected by DDT residues...
  32. ncbi request reprint A modified system to evaluate the potency of anti-oxidative compounds in different cell types in vitro
    D Mayer
    IIIrd Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    Eur J Med Res 6:201-8. 2001
    ..As this method was established on 24- and 48-well plates in other cell lines (Caco-2, HFP-1), too, screening of a large array of antioxidative compounds in different cell lines can be performed...
  33. ncbi request reprint Nutrition and aging: a consensus statement
    C J Bates
    Institut fur Biologische Chemie und Ernahrungswissenschaft, Universtat Hohenheim, Stuttgart, Germany
    J Nutr Health Aging 6:103-16. 2002
    ..To consider the relationship between nutrition and aging. To summarize existing knowledge and identify areas of ignorance...
  34. ncbi request reprint High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers
    A Mühlhöfer
    Division of Gastroenterology at Katharinenhospital, Stuttgart, Germany
    Eur J Clin Nutr 58:1151-8. 2004
    ..However, concerns are raised whether this approach might provoke diametrical (ie pro-oxidative) effects. The objective was to determine ascorbyl free radical (AFR) concentrations and potential variables of pro-oxidative damage...
  35. ncbi request reprint Determination of vitamin A palmitate in buccal mucosal cells: a pilot study
    U Sobeck
    University of Hohenheim, Department of Biological Chemistry and Nutrition, Fruwirthstr 12, D 70593 Stuttgart, Germany
    Eur J Med Res 7:287-9. 2002
    ..In this way metaplastic alterations of the buccal mucosal epithelium might be prevented or reversed by the application of topical retinyl palmitate...
  36. ncbi request reprint Dietary intake and nutritional status of women and pre-school children in the Republic of the Maldives
    A M Golder
    Institute of Biological Chemistry and Nutrition, University of Hohenheim, Garbenstrasse 30, D-70599 Stuttgart, Germany
    Public Health Nutr 4:773-80. 2001
    ..Higher intakes of locally available vegetables and fruits and fat (especially for children) on a regular basis might reverse the deficits documented on the atolls...
  37. ncbi request reprint Improved method for rapid determination of vitamin A in small samples of breast milk by high-performance liquid chromatography
    M Strobel
    Department of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
    J Chromatogr A 898:179-83. 2000
    ..The simple extraction and separation steps allow a high throughput screening under routine laboratory conditions...
  38. ncbi request reprint Possible protective effects of alpha-tocopherol on enhanced induction of reactive oxygen species by 2-methoxyestradiol in tumors
    Oliver Thews
    Adv Exp Med Biol 566:349-55. 2005
    ..Inhibition of SOD during ROS-generating hyperthermia results in pronounced cell injury and an improved local tumor control whereas exogenously applied vitamin E seems not to have an impact on oxidative stress...
  39. ncbi request reprint In vitro reproduction of clinical hallmarks of eczematous dermatitis in organotypic skin models
    Karin Engelhart
    BioTeSys GmbH, Schelztorstrasse 54 56, 73728 Esslingen, Germany
    Arch Dermatol Res 297:1-9. 2005
    ..Furthermore it can be concluded that these models make it possible to investigate targets of therapeutics in skin...