Research Topics
| Jürgen BiedererSummaryAffiliation: University of Kiel Country: Germany Publications
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Detail Information
Publications
Reproducible Simulation of Respiratory Motion in Porcine Lung ExplantsJ Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel
Rofo 178:1067-72. 2006..To develop a model for exactly reproducible respiration motion simulations of animal lung explants inside an MR-compatible chest phantom...
A hybrid breath hold and continued respiration-triggered technique for time-resolved 3D MRI perfusion studies in lung cancerC Hintze
Radiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg
Rofo 182:45-52. 2010..Therefore, we developed and evaluated an MR measurement technique that exceeds a single breath hold, and provides a variable temporal resolution during acquisition while suspending breath-dependent motion...
MRI of the lung (2/3). Why … when … how?J Biederer
University Hospital Schleswig Holstein, Campus Kiel, Department of Diagnostic Radiology, Arnold Heller Straße 3, Haus 23, 24105, Kiel, Germany
Insights Imaging 3:355-71. 2012..e. for paediatric patients and pregnant women or for scientific use. One of the reasons why MRI of the lung is still rarely used, except in a few centres, is the lack of consistent protocols customised to clinical needs...
MRI of the lung (3/3)-current applications and future perspectivesJürgen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Arnold Heller Straße 3, Haus 23, 24105, Kiel, Germany
Insights Imaging 3:373-86. 2012..MRI of the lung is recommended in a number of clinical indications. Having a non-radiation alternative is particularly attractive in children and young subjects, or pregnant women...
Suspected pulmonary artery disruption after transvenous pulmonary embolectomy using a hydrodynamic thrombectomy device: clinical case and experimental study on porcine lung explantsJürgen Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Germany
J Endovasc Ther 10:99-110. 2003..To use porcine lung explants for reconstructing possible situations in which a vessel wall disruption might have occurred in a patient suffering fatal hemoptysis after pulmonary embolectomy with a hydrodynamic thrombectomy device...
Correlation between HRCT findings, pulmonary function tests and bronchoalveolar lavage cytology in interstitial lung disease associated with rheumatoid arthritisJ Biederer
Department of Diagnostic Radiology, Christian Albrechts University Kiel, Arnold Heller Strasse 9, 24105 Kiel, Gemany
Eur Radiol 14:272-80. 2004..The PFT and BAL correlate only partially with lesion profusion or grading on HRCT, but they contribute valuable information about dynamic lung function and differential diagnoses (pneumonia, medication side effects)...
Volumetric interpolated contrast-enhanced MRA for the diagnosis of pulmonary embolism in an ex vivo systemJürgen Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Kiel, Germany
J Magn Reson Imaging 19:428-37. 2004..To implement a three-dimensional gradient-recalled echo (GRE) volumetric interpolated breath-hold examination (VIBE) sequence for pulmonary contrast-enhanced MRA (CE-MRA) in an experimental setup...
Pulmonary nodule detection with digital projection radiography: an ex-vivo study on increased latitude post-processingJuergen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Arnold Heller Str 9, Kiel, Germany
Eur Radiol 17:1089-100. 2007..94 with a specificity from 0.96 to 0.97 (all p>0.05). Increased latitude post-processing has minimal effects on the overall accuracy, but improves the detection confidence for sub-centimeter nodules in the posterior recesses of the lung...
Respiratory-gated helical computed tomography of lung: reproducibility of small volumes in an ex vivo modelJuergen Biederer
Department of Radiology, German Cancer Research Center, Heidelberg, Germany
Int J Radiat Oncol Biol Phys 69:1642-9. 2007..The objective was to evaluate the reproducibility of spatial information for small objects on respiratory-gated 4D helical CT using computer-assisted volumetry of lung nodules in a ventilated ex vivo system...
MRI of pulmonary nodules: technique and diagnostic valueJuergen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Germany
Cancer Imaging 8:125-30. 2008..The clinical value of time-resolved lung nodule perfusion analysis cannot yet be determined, although the combination of perfusion characteristics with morphologic criteria contributes to estimate the integrity of a solitary lesion...
4D-Imaging of the lung: reproducibility of lesion size and displacement on helical CT, MRI, and cone beam CT in a ventilated ex vivo systemJuergen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Germany
Int J Radiat Oncol Biol Phys 73:919-26. 2009..We evaluated in a ventilated ex vivo system how size and displacement of artificial pulmonary nodules are reproduced with helical 4D-CT, 4D-MRI, and linac-integrated cone beam CT (CBCT)...
[Investigation of respiratory-dependent movements of pulmonary space-occupying lesions with MRI]J Biederer
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Arnold Heller Str 9, 24105 Kiel
Radiologe 49:705-11. 2009..In addition 4D-MRI is available for a broad spectrum of scientific applications, as it allows repeated and prolonged series of measurements without radiation exposure...
[HRCT of the lung: nodular pattern: anatomy and differential diagnosis]J Biederer
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Arnold Heller Str 3, Haus 23, 24105, Kiel, Deutschland
Radiologe 50:553-66. 2010..Hence the subtle interpretation of specific findings on HRCT can contribute substantially to clinical decision making, although these signs may not always replace biopsy and histologic workup...
Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detectionJürgen Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Arnold Heller Strasse 9, Germany
Radiology 227:475-83. 2003..To evaluate the diagnostic accuracy of common magnetic resonance (MR) imaging sequences for detection of small pulmonary nodules by using a chest phantom and porcine lungs containing simulated lesions...
Artificial thorax for MR imaging studies in porcine heart-lung preparationsJürgen Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Arnold Heller Strasse 9, 24105 Kiel 1, Germany
Radiology 226:250-5. 2003..A variety of experiments with different imaging modalities, including angiography, under close to in vivo conditions are feasible. Access to bronchial system and lung vessels allows for various studies...
[Digital subtraction angiography of the extremities using step-translation technique]J Biederer
Klinik für Diagnostische Radiologie der Christian Albrechts Universität zu Kiel
Rofo 172:354-60. 2000..To evaluate, how routine application of i.a. DSA with the step-translation technique using a single contrast bolus can effectively reduce radiation exposure and the amount of contrast media in comparison to standard peripheral DSA...
Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patientsJürgen Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Arnold Heller Strasse 9, 24105 Kiel 1, Germany
Radiology 226:242-9. 2003....
[Sensitivity of MRI in detecting alveolar Infiltrates: Experimental studies]J Biederer
Klinik für Diagnostische Radiologie, Universitatsklinikum Kiel, Germany
Rofo 174:1033-9. 2002..An experimental study using porcine lung explants and a dedicated chest phantom to evaluate the signal intensity of artificial alveolar infiltrates with T 1 - and T 2 -weighted MRI sequences...
[The x-ray follow-up study of the cervical spine after anterior fusion with titanium disk implants]J Biederer
Klinik für Diagnostische Radiologie, Klinikum der Christian Albrechts Universität Kiel
Rofo 171:95-9. 1999..We examined the postoperative changes of the cervical spine after treatment of cervical nerve root compression with anterior cervical discectomy and fusion with a new titanium intervertebral disc...
[Rotational digital subtraction angiography of carotid bifurcation stenosis]J Biederer
Klinik für Diagnostische Radiologie, Christian Albrechts Universitat zu Kiel
Rofo 171:283-9. 1999..A prospective study was designed to evaluate, whether multiplanar imaging with rotational digital subtraction angiography (R-DSA) could improve assessment of carotid artery bifurcation stenosis...
[Contrast media-enhanced 3D MR angiography before endovascular treatment of aneurysm in the abdominal aorta, iliac artery and peripheral vessels]J Biederer
Klinik für Diagnostische Radiologie der Christian Albrechts Universität zu Kiel
Rofo 172:985-91. 2000..It was evaluated if additional gadolinium-enhanced three-dimensional MR angiography (3D-CEMRA) could compensate for the disadvantages of DSA...
Analysis of artefacts and detail resolution of lung MRI with breath-hold T1-weighted gradient-echo and T2-weighted fast spin-echo sequences with respiratory triggeringJ Biederer
Department of Diagnostic Radiology, University Hospital Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
Eur Radiol 12:378-84. 2002..Both sequences were found to be complementary: superior identification of gross lung anatomy with T1-weighted GRE and higher detail resolution in the periphery and the mediastinum with T2--weighted TSE...
Magnetic resonance imaging and computed tomography of respiratory mechanicsJürgen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Germany
J Magn Reson Imaging 32:1388-97. 2010....
Reproducibility of computer-aided volumetry of artificial small pulmonary nodules in ex vivo porcine lungsHendrik Bolte
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Germany
Invest Radiol 41:28-35. 2006..The main purpose of this study was to investigate the reproducibility of computed tomography (CT)-based volumetric measurements of small pulmonary nodules...
Treatment of acute pulmonary embolism: local effects of three hydrodynamic thrombectomy devices in an ex vivo porcine modelJürgen Biederer
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Germany
J Endovasc Ther 13:549-60. 2006..To report an ex vivo study on the local effects of hydrodynamic thrombectomy for the treatment of acute pulmonary embolism (off-label use)...
Magnetic resonance imaging of the lung with a volumetric interpolated 3D-gradient echo sequenceJ Biederer
Klinik für Diagnostische Radiologie, Universitatsklinikum Kiel, Germany
Rofo 173:883-7. 2001..To evaluate the feasibility of a magnetic resonance imaging protocol for the lung using a volumetric interpolated 3D-gradient echo sequence (3D-GRE)...
[Magnetic resonance imaging: technical aspects and recent developments]Jürgen Biederer
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus, Kiel
Med Klin (Munich) 100:62-72. 2005..Based on the knowledge of recent trends and technical backgrounds, many perspectives are opened up for the further development of the method in interdisciplinary cooperation...
In vivo Gd-DTPA concentration for MR lung perfusion measurements: assessment with computed tomography in a porcine modelMichael Puderbach
Department of Radiology, German Cancer Research Center, Heidelberg, Germany
Eur Radiol 18:2102-7. 2008..The CA dose for quantification of lung perfusion with time-resolved MR studies must be chosen carefully since even with low doses (0.05 mmol/kg) the CAC may exceed the range of linearity in the AIF...
Detection of respiratory motion in fluoroscopic images for adaptive radiotherapyT Moser
German Cancer Research Center, Heidelberg, Germany
Phys Med Biol 53:3129-45. 2008..This allows for the conclusion that it is possible to build up a gating system based on image data, solely, or (at least in avoidance of an exceeding exposure dose) to verify gates proposed by the various external systems...
Morphologic and functional scoring of cystic fibrosis lung disease using MRIMonika Eichinger
Department of Radiology, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Eur J Radiol 81:1321-9. 2012..This scoring-system can be applied for the routine assessment of CF lung disease and maybe as endpoint for clinical trials...
Dual energy computed tomography of lung nodules: differentiation of iodine and calcium in artificial pulmonary nodules in vitroNaomi Knöss
Department of Radiology, University Hospital Schleswig Holstein, Campus Kiel, Germany
Eur J Radiol 80:e516-9. 2011..The purpose of this in vitro study was to assess whether dual energy computed tomography (DECT) can be used to detect iodine and to distinguish iodine from disperse calcifications in artificial pulmonary nodules...
Lung nodule assessment in computed tomography: precision of attenuation measurement based on computer-aided volumetryN Knöss
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
Rofo 181:1151-6. 2009..To compare the reproducibility (r) of CT value measurement of pulmonary nodules using volumetry software (LungCare, LC) and manual ROIs (mROI)...
[Comparison of biphasic spiral CT and MnDPDP-enhanced MRI in the detection and characterization of liver lesions]J Grimm
Klinik für Diagnostische Radiologie, CAU Kiel
Rofo 173:266-72. 2001..To evaluate the efficacy of biphasic spiral CT and MnDPDP (Teslascan, Nycomed Amersham) enhanced MR imaging to detect and classify liver lesions...
[Lung cancer staging]C Hintze
Klinik für Diagnostische Radiologie, Universitätsklinikum Schleswig Holstein Campus Kiel, Arnold Heller Str 3 Haus 23, 24105 Kiel, Deutschland
Radiologe 51:135-44. 2011..Current guidelines as well as the current TNM system are presented. The usefulness of modern cross-sectional imaging and the possible modalities in this system is reported...
Semi-automated volumetric analysis of lymph node metastases during follow-up--initial resultsMichael Fabel
University Hospital Schleswig Holstein, Campus Kiel, Arnold Heller Str 23, Haus 23, 24105 Kiel, Germany
Eur Radiol 21:683-92. 2011..Volumetric analysis is an alternative for therapy monitoring. The aim of this study was to evaluate the feasibility of volumetric analysis of lymph node metastases using a software prototype in a follow-up setting...
[New procedures. Comprehensive staging of lung cancer by MRI]C Hintze
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Arnold Heller Str 3 Haus 23, 24105, Kiel, Deutschland
Radiologe 50:699-705. 2010..In the oncological context the most important techniques are imaging of perfusion and tumor motion. Functional MRI of the lungs complements the pure staging and improves surgical approaches and radiotherapy planning...
Quantitation of renal perfusion using arterial spin labeling with FAIR-UFLAREN Karger
Klinikum an der CAU zu Kiel, Klinik für Diagnostische Radiologie, Michaelisstr 9, 24105, Kiel, Germany
Magn Reson Imaging 18:641-7. 2000....
[Vasculitis--interdisciplinary diagnosis: radiology]M Reuter
Klinik für Diagnostische Radiologie Universitätsklinikum Kiel Arnold Heller Str 9 24109 Kiel
Z Rheumatol 60:243-54. 2001..Diagnostic imaging does substantially assist in the interdisciplinary management of patients suffering from vasculitides...
MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference studyM Fabel
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Arnold Heller Str 9, 24105 Kiel, Germany
Eur Radiol 19:391-9. 2009..At 1.5 T, a modified SSFP with moderate parallel imaging (PI factor 2) was considered the best compromise of temporal and spatial resolution. At 3 T, GRE sequences remain the best choice for dynamic lung MRI...
[Radiology of the primary systemic vasculitides]M Reuter
Klinik für Diagnostische Radiologie, Universitatsklinikum Kiel
Rofo 175:1184-92. 2003..Diagnostic imaging does substantially assist in the interdisciplinary management of patients suffering from vasculitides...
[High-resolution computed tomography of the lungs in pediatric patients]M Reuter
Klinik für Diagnostische Radiologie, Universitatsklinikum, Kiel, Germany
Rofo 174:684-95. 2002..The indication for pediatric pulmonary HRCT is limited to selected cases and it should be decided in agreement with the pediatric radiologists and the pediatric pulmonologists...
[Inflammatory aortic arch syndrome: contrast-enhanced, three-dimensional MR angiography in stenotic lesions]M Both
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel
Rofo 176:48-55. 2004..To determine the value of contrast-enhanced, three-dimensional MR angiography for the evaluation of stenotic and occlusive vascular lesions in inflammatory aortic arch syndrome...
[Early results with a monorail-stent-balloon device for endovascular treatment of renal artery stenosis]S Muller-Hulsbeck
Universitatsklinikum Kiel, Klinik für Diagnostische Radiologie, Christian Albrechts Universitat zu Kiel, Germany
Rofo 174:335-41. 2002..To evaluate the technical feasibility of a new monorail-stent-balloon device for treatment of renal artery stenosis (RAS)...
Ex-vivo injection technique for implanting solid pulmonary nodules into porcine lungs for multi-slice CTH Bolte
Klinik für Diagnostische Radiologie, Universitätsklinikum Schleswig Holstein Campus Kiel, Kiel, Germany
Rofo 176:1380-4. 2004..To develop a method for generating realistic pulmonary nodules that equal small pulmonary metastases and granulomas...
Percutaneous management of occlusive arterial disease associated with vasculitis: a single center experienceM Both
Department of Radiology, Christian Albrechts University of Kiel, Kiel, Germany
Cardiovasc Intervent Radiol 26:19-26. 2003..9%. Interventional therapy in systemic vasculitis provides promising results in technical success rates and followup. Angioplasty may result in arterial injury, but the rate of complications is low...
Fast T1- and T2-weighted pulmonary MR-imaging in patients with bronchial carcinomaM Both
Department of Diagnostic Radiology, University Hospital Schleswig Holstein, Campus Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
Eur J Radiol 53:478-88. 2005..A prospective study to evaluate the diagnostic potential and limitations of three fast MRI sequences in patients with bronchial carcinoma based on the comparison with spiral CT...
Computed tomography-based lung nodule volumetry--do optimized reconstructions of routine protocols achieve similar accuracy, reproducibility and interobserver variability to that of special volumetry protocols?H Bolte
Klinik für Diagnostische Radiologie, Universitatsklinikum Schleswig Holstein, Campus Kiel
Rofo 179:276-81. 2007....
Interobserver-variability of lung nodule volumetry considering different segmentation algorithms and observer training levelsH Bolte
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
Eur J Radiol 64:285-95. 2007..A special interest was the consideration of different measurement methods, observer experience and training levels...
Precision of computer-aided volumetry of artificial small solid pulmonary nodules in ex vivo porcine lungsH Bolte
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
Br J Radiol 80:414-21. 2007..3% (+/-6.9%) for manually corrected volumetry. We conclude that the presented software allowed for precise volumetry of artificial nodules in ex vivo lung tissue. This result is comparable to the findings of previous in vitro studies...
Low dose MDCT of the wrist--an ex vivo approachH Bolte
Department of Diagnostic Radiology, University Hospital Schleswig Holstein Campus Kiel, Arnold Heller Strasse 9, 24105 Kiel, Germany
Eur J Radiol 77:207-14. 2011..In MDCT of the wrist good image quality could be maintained while radiation dose was considerably reduced. A reduction of voltage offers the best result for a solely parameter change...
Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lungGrzegorz Bauman
Division of Medical Physics in Radiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Radiology 260:551-9. 2011....
Magnetic resonance-compatible-spirometry: principle, technical evaluation and applicationM Eichinger
Department of Radiology E010, Deutsches Krebsforschungszentrum DKFZ, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
Eur Respir J 30:972-9. 2007..Dynamic magnetic resonance imaging measurements correlate well with simultaneously acquired lung function parameters...
DC-gated high resolution three-dimensional lung imaging during free-breathingStefan Weick
Department of Experimental Physics 5, University of Wuerzburg, Germany
J Magn Reson Imaging 37:727-32. 2013....
CT-guided lymphoscintigraphy in patients with squamous cell carcinoma of the head and neck: a feasibility studyClaus Muhle
Clinic of Nuclear Medicine, University of Schleswig Holstein Kiel, Campus Kiel, Germany
Eur J Nucl Med Mol Imaging 31:940-4. 2004..In contrast to endoscopic colloid injection under general anaesthesia, this technique seems to be a well-tolerated method for lymphatic mapping prior to surgical procedures...
[The role of magnetic resonance imaging in the preoperative evaluation of the peripancreatic vasculature in pancreas carcinoma]F Helmreich
, , Campus Kiel
Rofo 176:239-45. 2004..A combined protocol of MRA and MRI is needed for an acceptable evaluation of the peripancreatic vessels...
Four-dimensional multislice helical CT of the lung: qualitative comparison of retrospectively gated and static images in an ex-vivo systemJulien Dinkel
Department of Radiooncology, Radiology, University Hospital Heidelberg, Germany
Radiother Oncol 85:215-22. 2007..To analyse the image quality of retrospectively gated helical CT using controlled respiratory motion of porcine lung explants...
Lung MRI at 1.5 and 3 Tesla: observer preference study and lesion contrast using five different pulse sequencesChristian Fink
Department of Clinical Radiology, University Hospitals Grosshadern, Ludwig Maximilians University, Munich, Germany
Invest Radiol 42:377-83. 2007..To compare the image quality and lesion contrast of lung MRI using 5 different pulse sequences at 1.5 T and 3 T...
Therapy monitoring using dynamic MRI: analysis of lung motion and intrathoracic tumor mobility before and after radiotherapyChristian Plathow
Department of Diagnostic Radiology, Eberhard Karls University Tuebingen, Hoppe Seyler 3, 72060, Tuebingen, Germany
Eur Radiol 16:1942-50. 2006..This might make the treatment of side effects possible at a very early stage. Changes of lung motion and tumor mobility are highly dependent on the tumor localization and tumor diameter...
