T Bertsch

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint A new sensitive cardiac Troponin T rapid test (TROPT) for the detection of experimental acute myocardial damage in rats
    T Bertsch
    Institute for Clinical Chemistry, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Germany
    Exp Toxicol Pathol 51:565-9. 1999
  2. ncbi request reprint Hypertonic-hyperoncotic solutions decrease cardiac troponin I concentrations in peripheral blood in a porcine ischemia-reperfusion model
    T Bertsch
    Institute for Clinical Chemistry, Klinikum Mannheim gGmbH, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Germany
    Exp Toxicol Pathol 53:153-6. 2001
  3. ncbi request reprint Protein S-100B: a serum marker for ischemic and infectious injury of cerebral tissue
    T Bertsch
    Departmentof Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:319-23. 2001
  4. ncbi request reprint Homocysteine in cerebrovascular disease: an independent risk factor for subcortical vascular encephalopathy
    T Bertsch
    Department of Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:721-4. 2001
  5. ncbi request reprint Cardiac troponin I and cardiac troponin T increases in pigs during ischemia-reperfusion damage
    T Bertsch
    Institute for Clinical Chemistry, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Mannheim, Germany
    Exp Toxicol Pathol 52:157-9. 2000
  6. ncbi request reprint Endothelin-1 in subarachnoid hemorrhage: An acute-phase reactant produced by cerebrospinal fluid leukocytes
    K Fassbender
    Department of Neurology, Clinic Mannheim, University of Heidelberg, Germany
    Stroke 31:2971-5. 2000
  7. pmc Inflammatory cytokines in subarachnoid haemorrhage: association with abnormal blood flow velocities in basal cerebral arteries
    K Fassbender
    Department of Neurology, University Clinic Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer, 68135 Mannheim, Germany
    J Neurol Neurosurg Psychiatry 70:534-7. 2001
  8. ncbi request reprint Temporal profile of release of interleukin-1beta in neurotrauma
    K Fassbender
    Department of Neurology, University Clinic Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68135, Mannheim, Germany
    Neurosci Lett 284:135-8. 2000
  9. ncbi request reprint Source of endothelin-1 in subarachnoid hemorrhage
    T Bertsch
    Department of Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:341-5. 2001
  10. ncbi request reprint Aggregation-Dependent interaction of the Alzheimer's beta-amyloid and microglia
    F Muehlhauser
    Department of Neurology, University of Heidelberg, Mannheim, Germany
    Clin Chem Lab Med 39:313-6. 2001

Detail Information

Publications12

  1. ncbi request reprint A new sensitive cardiac Troponin T rapid test (TROPT) for the detection of experimental acute myocardial damage in rats
    T Bertsch
    Institute for Clinical Chemistry, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Germany
    Exp Toxicol Pathol 51:565-9. 1999
    ..If the time range between the induction of the injury and the use of the test strip or the ELISA procedure is too wide, in our experiments 24 h, false negative results may occur...
  2. ncbi request reprint Hypertonic-hyperoncotic solutions decrease cardiac troponin I concentrations in peripheral blood in a porcine ischemia-reperfusion model
    T Bertsch
    Institute for Clinical Chemistry, Klinikum Mannheim gGmbH, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Germany
    Exp Toxicol Pathol 53:153-6. 2001
    ..We observed that cTnI serum levels of animals treated with hypertonic-hyperoncotic solutions were significantly lower than those treated with saline. We conclude that hypertonic-hyperoncotic solutions may have cardioprotective effects...
  3. ncbi request reprint Protein S-100B: a serum marker for ischemic and infectious injury of cerebral tissue
    T Bertsch
    Departmentof Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:319-23. 2001
    ..In conclusion, serum levels of S-100B reflect the time course of tissue injury in cerebral ischemia and cerebral infection to a similar extent. Thus, S-100B may be a useful marker to assess cerebral tissue injury...
  4. ncbi request reprint Homocysteine in cerebrovascular disease: an independent risk factor for subcortical vascular encephalopathy
    T Bertsch
    Department of Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:721-4. 2001
    ..7; CI 2.5-12.9) in comparison to other vascular risk factors such as hypertension, age and smoking. These observations indicate that hyperhomocysteinemia is a strong independent risk factor for SVE...
  5. ncbi request reprint Cardiac troponin I and cardiac troponin T increases in pigs during ischemia-reperfusion damage
    T Bertsch
    Institute for Clinical Chemistry, Faculty of Clinical Medicine Mannheim of the University of Heidelberg, Mannheim, Germany
    Exp Toxicol Pathol 52:157-9. 2000
    ..Further studies are needed for correlation of troponin serum levels and histopathological damage in this model especially if it is used to test beneficial or toxicological effects of radical neutralizing drugs...
  6. ncbi request reprint Endothelin-1 in subarachnoid hemorrhage: An acute-phase reactant produced by cerebrospinal fluid leukocytes
    K Fassbender
    Department of Neurology, Clinic Mannheim, University of Heidelberg, Germany
    Stroke 31:2971-5. 2000
    ..In our study, we performed clinical and in vitro experiments to investigate the origin and the mechanisms of the secretion of endothelin-1 in SAH...
  7. pmc Inflammatory cytokines in subarachnoid haemorrhage: association with abnormal blood flow velocities in basal cerebral arteries
    K Fassbender
    Department of Neurology, University Clinic Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer, 68135 Mannheim, Germany
    J Neurol Neurosurg Psychiatry 70:534-7. 2001
    ..Together, these findings suggest a role of excessive compartmentalised inflammatory host response in pathogenesis of cerebrovascular complications after SAH...
  8. ncbi request reprint Temporal profile of release of interleukin-1beta in neurotrauma
    K Fassbender
    Department of Neurology, University Clinic Mannheim, University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68135, Mannheim, Germany
    Neurosci Lett 284:135-8. 2000
    ..This so far unrecognized acuity of IL-1beta release demonstrated here, may represent a precondition for the orchestrating role of this mediator in the cascade of inflammatory host response...
  9. ncbi request reprint Source of endothelin-1 in subarachnoid hemorrhage
    T Bertsch
    Department of Clinical Chemistry, Clinic Mannheim, University of Heidelberg, Germany
    Clin Chem Lab Med 39:341-5. 2001
    ..This finding may have important therapeutic implications as anti-leukocyte strategies could prevent cerebrovascular complications in SAH patients...
  10. ncbi request reprint Aggregation-Dependent interaction of the Alzheimer's beta-amyloid and microglia
    F Muehlhauser
    Department of Neurology, University of Heidelberg, Mannheim, Germany
    Clin Chem Lab Med 39:313-6. 2001
    ..In the case of the living brain, the presence of deposits of fibrillar amyloid peptide could maintain a chronic microglial activation, ultimately leading to the progressive neurodegeneration associated with Alzheimer's disease...
  11. ncbi request reprint Parameters for determination of Candida albicans virulence in murine peritonitis
    M Kretschmar
    Institut fur Medizinische Mikrobiologie und Hygiene, Klinikum Mannheim, Germany
    Mycoses 42:19-24. 1999
    ..albicans to invade neighbouring organs, to reach the brain upon dissemination and germination in the brain and kidneys may be used for measurement of virulence in this model when virulence is defined as lethality...
  12. pmc Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
    K Fassbender
    Department of Neurology, Clinic Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany
    Proc Natl Acad Sci U S A 98:5856-61. 2001
    ..Lowered levels of Abeta42 may provide the mechanism for the observed reduced incidence of dementia in statin-treated patients and may open up avenues for therapeutic interventions...