Christian Bernreuther

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Expression of doublecortin in tumours of the central and peripheral nervous system and in human non-neuronal tissues
    Christian Bernreuther
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Acta Neuropathol 111:247-54. 2006
  2. doi request reprint Transplanted L1 expressing radial glia and astrocytes enhance recovery after spinal cord injury
    Jin Chong Xu
    Zentrum fur Molekulare Neurobiologie Hamburg, Hamburg, Germany
    J Neurotrauma 28:1921-37. 2011
  3. doi request reprint In vitro generation of three-dimensional substrate-adherent embryonic stem cell-derived neural aggregates for application in animal models of neurological disorders
    Gunnar Hargus
    Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Curr Protoc Stem Cell Biol . 2012
  4. doi request reprint Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
    Mathias Gelderblom
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurobiol Dis 59:177-82. 2013
  5. doi request reprint Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells
    Shan Bian
    Zentrum für Molekulare Neurobiologie, Universitätskrankenhaus Hamburg Eppendorf, Universitat Hamburg, Martinistr 52, D 20246 Hamburg, Germany
    J Cell Sci 124:4051-63. 2011
  6. doi request reprint Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression
    Ingo D Meier
    Center for Molecular Neurobiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    FASEB J 24:1714-24. 2010
  7. ncbi request reprint A new role for the cell adhesion molecule L1 in neural precursor cell proliferation, differentiation, and transmitter-specific subtype generation
    Marcel Dihné
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg, D 20251 Hamburg, Germany
    J Neurosci 23:6638-50. 2003
  8. ncbi request reprint Osseous changes in meningioma en plaque
    Jakob Matschke
    Institute of Pathology, University Medical Center, Hamburg Eppendorf, 20246 Hamburg, Germany
    Anticancer Res 31:591-6. 2011
  9. doi request reprint Hypophysectomy for prostate cancer: a revival of old knowledge?
    Jörg Flitsch
    Pituitary Unit, Department of Neurosurgery, Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Neurosurg 109:760-4. 2008
  10. doi request reprint Adhesion molecule L1 is down-regulated in malignant peripheral nerve sheath tumors versus benign neurofibromatosis type 1-associated tumors
    Marco Blessmann
    Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg Eppendorf, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol 113:239-44. 2012

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Expression of doublecortin in tumours of the central and peripheral nervous system and in human non-neuronal tissues
    Christian Bernreuther
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Acta Neuropathol 111:247-54. 2006
    ....
  2. doi request reprint Transplanted L1 expressing radial glia and astrocytes enhance recovery after spinal cord injury
    Jin Chong Xu
    Zentrum fur Molekulare Neurobiologie Hamburg, Hamburg, Germany
    J Neurotrauma 28:1921-37. 2011
    ....
  3. doi request reprint In vitro generation of three-dimensional substrate-adherent embryonic stem cell-derived neural aggregates for application in animal models of neurological disorders
    Gunnar Hargus
    Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    Curr Protoc Stem Cell Biol . 2012
    ....
  4. doi request reprint Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
    Mathias Gelderblom
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurobiol Dis 59:177-82. 2013
    ..We aimed at validating a plasma biomarker for neuronal damage that can be used in acute and chronic models of neurological diseases...
  5. doi request reprint Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells
    Shan Bian
    Zentrum für Molekulare Neurobiologie, Universitätskrankenhaus Hamburg Eppendorf, Universitat Hamburg, Martinistr 52, D 20246 Hamburg, Germany
    J Cell Sci 124:4051-63. 2011
    ..By contrast, deficiency in Chst11 did not influence NSC proliferation, migration or differentiation. These observations indicate for the first time that CSs and DSs play distinct roles in the self-renewal and differentiation of NSCs...
  6. doi request reprint Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression
    Ingo D Meier
    Center for Molecular Neurobiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    FASEB J 24:1714-24. 2010
    ..Our results imply that conditional knockout mice should be analyzed for genomic positional side effects that may influence the animals' phenotypes...
  7. ncbi request reprint A new role for the cell adhesion molecule L1 in neural precursor cell proliferation, differentiation, and transmitter-specific subtype generation
    Marcel Dihné
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg, D 20251 Hamburg, Germany
    J Neurosci 23:6638-50. 2003
    ..Our observations support a new role for L1 or L1 ligands in neural precursor cell proliferation and differentiation...
  8. ncbi request reprint Osseous changes in meningioma en plaque
    Jakob Matschke
    Institute of Pathology, University Medical Center, Hamburg Eppendorf, 20246 Hamburg, Germany
    Anticancer Res 31:591-6. 2011
    ....
  9. doi request reprint Hypophysectomy for prostate cancer: a revival of old knowledge?
    Jörg Flitsch
    Pituitary Unit, Department of Neurosurgery, Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Neurosurg 109:760-4. 2008
    ....
  10. doi request reprint Adhesion molecule L1 is down-regulated in malignant peripheral nerve sheath tumors versus benign neurofibromatosis type 1-associated tumors
    Marco Blessmann
    Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg Eppendorf, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol 113:239-44. 2012
    ..Future studies are warranted to elucidate the molecular basis of the varying effects of the degree of L1 expression, receptor, and signal transduction mechanisms in different tumors...
  11. pmc Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice
    Yi Fang Cui
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitätskrankenhaus Hamburg Eppendorf, Universitat Hamburg, Hamburg, Germany
    PLoS ONE 6:e17126. 2011
    ....
  12. doi request reprint Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease
    Diego Sepulveda-Falla
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Brain Pathol 21:452-63. 2011
    ..The presence of pTau in cerebellum in PS1-E280A underscores the relevance of cerebellar involvement in AD and might be correlated to clinical phenotype...
  13. ncbi request reprint Cell adhesion molecule l1-transfected embryonic stem cells with enhanced survival support regrowth of corticospinal tract axons in mice after spinal cord injury
    Jian Chen
    Zentrum für Molekulare Neurobiologie, Universitat Hamburg, Hamburg, Germany
    J Neurotrauma 22:896-906. 2005
    ..Their use could condition the inhibitory environment for homophilic L1-enhanced axon regrowth not only in spinal cord regeneration, but also in other lesion paradigms...
  14. pmc Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
    Mathias Gelderblom
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 8:e63118. 2013
    ..Our results show excessive microglial activation in Ns(-/-) mice mediated by an increased activity of tPA. This activation results in a worse outcome further underscoring the potential detrimental proinflammatory effects of tPA...
  15. pmc Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo
    Hermann C Altmeppen
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    Mol Neurodegener 6:36. 2011
    ..abstract:..
  16. doi request reprint Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum
    Gunnar Hargus
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitatskrankenhaus Eppendorf, Universitat Hamburg, Martinistr 52, 20246 Hamburg, Germany
    Stem Cells 26:1973-84. 2008
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  17. doi request reprint Glycomimetic improves recovery after femoral injury in a non-human primate
    Andrey Irintchev
    Zentrum für Molekulare Neurobiologie, Universitat Hamburg, Martinistrasse 52, Hamburg, Germany
    J Neurotrauma 28:1295-306. 2011
    ..These results indicate the potential of the HNK-1 mimetic as an efficient, feasible, and safe adjunct treatment for nerve injuries requiring surgical repair in clinical settings...
  18. ncbi request reprint Embryonic stem cell-derived neuronally committed precursor cells with reduced teratoma formation after transplantation into the lesioned adult mouse brain
    Marcel Dihné
    Zentrum für Molekulare Neurobiologie, Universitat Hamburg, Germany
    Stem Cells 24:1458-66. 2006
    ..Purified SENAs that were differentiated into immature but postmitotic neurons did not form tumors up to four months after syngeneic transplantation into the acutely degenerated striatum and showed robust survival...
  19. ncbi request reprint Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum
    Christian Bernreuther
    Zentrum fur Molekulare Neurobiologie Hamburg, University of Hamburg, D 20251 Hamburg, Germany
    J Neurosci 26:11532-9. 2006
    ....
  20. ncbi request reprint Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease
    Verena Johann
    Department of Neurology, University Hospital RWTH, Pauwelsstr 30, 52074 Aachen, Germany
    Exp Brain Res 177:458-70. 2007
    ....
  21. ncbi request reprint Neuronal differentiation of transplanted embryonic stem cell-derived precursors in stroke lesions of adult rats
    Claudia Bühnemann
    Leibniz Institut für Neurobiologie IfN, Neuropharmakologie, Magdeburg, Germany e mail
    Brain 129:3238-48. 2006
    ..Thus, our observations show that ESC-based regenerative approaches may be successful in an acutely necrotic cellular environment...
  22. doi request reprint Proteome analysis of ventral midbrain in MPTP-treated normal and L1cam transgenic mice
    Madeleine Diedrich
    Institute for Human Genetics, Charite Universitatsmedizin Berlin, Berlin, Germany
    Proteomics 8:1266-75. 2008
    ..This pattern indicates a lasting severely impaired energy production in L1cam mice after MPTP treatment...
  23. ncbi request reprint The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis
    Silke Walter
    Department of Neurology, Saarland University Hospital, Homburg, Germany
    Cell Physiol Biochem 17:167-72. 2006
    ..Thus, the key innate immune receptor, CD14, may be of pathophysiological relevance in experimental autoimmune encephalomyelitis and multiple sclerosis...
  24. doi request reprint A 61-year-old man with hyponatremia
    Christian Bernreuther
    Brain Pathol 18:283-7. 2008
    ..However, rare entities like schwannomas, melanocytomas or pituicytomas have to be considered in addition to the more common tumors like pituitary adenomas and meningiomas...