Christian Berger

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi request reprint Neurochemical monitoring of therapeutic effects in large human MCA infarction
    C Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 9:352-6. 2008
  2. doi request reprint Neuroprotection and glutamate attenuation by acetylsalicylic acid in temporary but not in permanent cerebral ischemia
    C Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Exp Neurol 210:543-8. 2008
  3. ncbi request reprint Neuroprotection by pravastatin in acute ischemic stroke in rats
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    Brain Res Rev 58:48-56. 2008
  4. ncbi request reprint Hypothermia in acute stroke--slow versus fast rewarming an experimental study in rats
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Exp Neurol 204:131-7. 2007
  5. ncbi request reprint Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    J Neurochem 88:1159-67. 2004
  6. ncbi request reprint Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study
    Wolf R Schabitz
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:2112-4. 2002
  7. ncbi request reprint Hypothermia and brain-derived neurotrophic factor reduce glutamate synergistically in acute stroke
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    Exp Neurol 185:305-12. 2004
  8. ncbi request reprint Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Stroke 36:e4-6. 2005
  9. ncbi request reprint Influence of intraventricular hemorrhage and occlusive hydrocephalus on the long-term outcome of treated patients with basal ganglia hemorrhage: a case-control study
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Germany
    J Neurosurg 105:412-7. 2006
  10. ncbi request reprint Reduction of diffusion-weighted MRI lesion volume after early moderate hypothermia in ischemic stroke
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Stroke 36:e56-8. 2005

Detail Information

Publications29

  1. doi request reprint Neurochemical monitoring of therapeutic effects in large human MCA infarction
    C Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 9:352-6. 2008
    ..In order to assess the potential effects of hemicraniectomy, hypothermia and conservative therapy on these substances, we used neurochemical monitoring with microdialysis in large human stroke patients...
  2. doi request reprint Neuroprotection and glutamate attenuation by acetylsalicylic acid in temporary but not in permanent cerebral ischemia
    C Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Exp Neurol 210:543-8. 2008
    ..These results suggest that the neuroprotective effect of ASA is reflected by glutamate attenuation and IL-6 induction even if given after stroke onset, but only if reperfusion is achieved...
  3. ncbi request reprint Neuroprotection by pravastatin in acute ischemic stroke in rats
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    Brain Res Rev 58:48-56. 2008
    ..In conclusion, a relatively high dose of pravastatin administered repetitively after stroke onset improved neurological outcome through various cholesterol-independent mechanisms...
  4. ncbi request reprint Hypothermia in acute stroke--slow versus fast rewarming an experimental study in rats
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Exp Neurol 204:131-7. 2007
    ..It may blunt deleterious rebound effects such as overexpression of AQP4, sustain anti-inflammatory mechanisms and thereby preserve the neuroprotection delivered by hypothermia...
  5. ncbi request reprint Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    J Neurochem 88:1159-67. 2004
    ..NAE accumulation during acute stroke may be due to increased synthesis as well as decreased degradation, possibly by inhibition of fatty acid amide hydrolase (FAAH)...
  6. ncbi request reprint Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study
    Wolf R Schabitz
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:2112-4. 2002
    ..We therefore studied release of FAEs such as anandamide, palmitylethanolamide (PEA), and oleylethanolamide (OEA) in the brain of a patient suffering from malignant hemispheric infarction treated with hypothermia...
  7. ncbi request reprint Hypothermia and brain-derived neurotrophic factor reduce glutamate synergistically in acute stroke
    Christian Berger
    Department of Neurology, University of Heidelberg, Germany
    Exp Neurol 185:305-12. 2004
    ..Combining hypothermia and BDNF therapy in the acute stage of ischemia has a synergistic effect in attenuating striatal glutamate release and reducing early infarct size...
  8. ncbi request reprint Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Stroke 36:e4-6. 2005
    ..Osmotic agents such as glycerol are used to treat brain edema in stroke patients. We investigated the pharmacokinetics of glycerol in brain tissue by cerebral microdialysis...
  9. ncbi request reprint Influence of intraventricular hemorrhage and occlusive hydrocephalus on the long-term outcome of treated patients with basal ganglia hemorrhage: a case-control study
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Germany
    J Neurosurg 105:412-7. 2006
    ..The aim of this study was to compare the long-term outcome of patients with pure ganglionic hemorrhage and those requiring an EVD due to additional IVH and hydrocephalus...
  10. ncbi request reprint Reduction of diffusion-weighted MRI lesion volume after early moderate hypothermia in ischemic stroke
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Stroke 36:e56-8. 2005
    ..A reduction of diffusion-weighted MRI (DWI) lesions occurs in 20% to 40% of acute stroke patients with early reperfusion...
  11. ncbi request reprint High-dose aspirin is neuroprotective in a rat focal ischemia model
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, 69120, Germany
    Brain Res 998:237-42. 2004
    ..0029), but not of 20 mg/kg ASA (129+/-19 mm(3), n=15), reduced infarct volume significantly. No significant change was noted with 40 mg/kg ASA injected only once at 30 min after MCAO (117+/-16 mm(3), n=13)...
  12. ncbi request reprint Neuroprotection by early and delayed treatment of acute stroke with high dose aspirin
    Zhao Zheng
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
    Brain Res 1186:275-80. 2007
    ..0046) and significant smaller infarct size (6 h, 57+/-9 mm(3), n=10, p=0.0043) compared to the saline control group (110+/-13 mm(3), n=10). Thus, there may be a relatively wide time window for acute stroke therapy with high dose Aspirin...
  13. ncbi request reprint Effects of hypothermia on excitatory amino acids and metabolism in stroke patients: a microdialysis study
    Christian Berger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:519-24. 2002
    ....
  14. ncbi request reprint Predictive factors for tracheostomy in neurocritical care patients with spontaneous supratentorial hemorrhage
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Cerebrovasc Dis 21:159-65. 2006
    ....
  15. ncbi request reprint Isolated sarcoid myopathy
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Muscle Nerve 26:553-6. 2002
    ..The patient was started on methylprednisolone and recovered to some extent. These findings represent a rare case of isolated sarcoid myopathy without concurrent systemic sarcoidosis...
  16. ncbi request reprint Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction
    W R Schäbitz
    Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
    Cerebrovasc Dis 12:298-302. 2001
    ..Microdialysis monitoring of therapeutic hypothermia in severe hemispheric infarction might be a useful additional monitoring tool to assess the status of the brain and to predict further deterioration...
  17. ncbi request reprint Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?
    C Berger
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:1330-5. 2001
    ..The aim of this study was to assess which type of HT independently affects clinical outcome...
  18. ncbi request reprint [Cerebral microdialysis in stroke]
    C Berger
    Neurologische Universitatsklinik, Heidelberg
    Nervenarzt 75:113-23. 2004
    ....
  19. ncbi request reprint Effect of brain-derived neurotrophic factor treatment and forced arm use on functional motor recovery after small cortical ischemia
    W R Schäbitz
    Department of Neurology, University of Heidelberg, INF 400, 69120 Heidelberg, Germany
    Stroke 35:992-7. 2004
    ..We explored the effects of these therapies on behavioral recovery and molecular markers of regeneration after experimental ischemia...
  20. ncbi request reprint Progressive visual loss due to a muslinoma--report of a case and review of the literature
    C Berger
    Department of Neurology, University of Heidelberg, Germany
    Eur J Neurol 10:153-8. 2003
    ..Various treatment strategies include surgery, steroids and cyclophosphamide, but recovery of the vision is not predictable. As a consequence, muslin or cotton gauze should only be applied with great caution in neurovascular surgery...
  21. ncbi request reprint Severe forward flexion of the trunk in Parkinson's disease: focal myopathy of the paraspinal muscles mimicking camptocormia
    Wolf Rüdiger Schäbitz
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Mov Disord 18:408-14. 2003
    ..In parkinsonian patients with pronounced forward flexion of the trunk, myopathy confined to the erector spinae muscles must be considered...
  22. ncbi request reprint Serum procalcitonin in cerebral ventriculitis
    Christian Berger
    Department of Neurology and Neurosurgery, University of Heidelberg, Germany
    Crit Care Med 30:1778-81. 2002
    ..The objective of this study was to test the hypothesis that serum procalcitonin is increased in patients with bacterial cerebral ventricular infections after the insertion of temporary external ventricular drains...
  23. ncbi request reprint Severe ethylene glycol intoxication mimicking acute basilar artery occlusion
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Neurocrit Care 3:171-3. 2005
    ..This report describes a new clinical presentation of severe ethylene glycol intoxication mimicking acute basilar artery occlusion with the development of a fatal brain edema within hours, despite adequate treatment...
  24. ncbi request reprint Head retraction reflex in stiff-man syndrome and related disorders
    Christian Berger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Mov Disord 18:906-11. 2003
    ....
  25. ncbi request reprint Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra
    Clemens Sommer
    Department of Neuropathology, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany
    Acta Neuropathol 112:277-86. 2006
    ..In summary, our data suggest that SR141716A may possess additional intrinsic neuroprotective properties independent of receptor-coupled pathways or due to action as a partial agonist...
  26. ncbi request reprint Editorial comment--"malignant" or not: is there a role for in vivo neurochemistry?
    Christian Berger
    Stroke 34:2914-5. 2003
  27. ncbi request reprint A critical role for cyclin E in cell fate determination in the central nervous system of Drosophila melanogaster
    Christian Berger
    Institute for Genetics, University of Mainz, D 55099 Mainz, Germany
    Nat Cell Biol 7:56-62. 2005
    ..However, other components of the cell cycle seem to have a minor role in this process, suggesting a critical role for CycE in regulating cell fate in segment-specific neural lineages...
  28. ncbi request reprint CSF-air-exchange for pharmacorefractory status epilepticus
    Martin Kohrmann
    J Neurol 253:1100-1. 2006
  29. ncbi request reprint Oxidative stress, mitochondrial permeability transition, and cell death in Cu-exposed trout hepatocytes
    Gerhard Krumschnabel
    Institut für Zoologie und Limnologie and Center for Molecular Biosciences Innsbruck CMBI, Abteilung für Okophysiologie, Universitat Innsbruck, Technikerstrasse 25, A 6020 Innsbruck, Austria
    Toxicol Appl Pharmacol 209:62-73. 2005
    ..Cu-induced apoptosis therefore appears to be dependent on induction of the MPT, but the prominent contribution of mitochondria to ROS generation also suggests an important role of mitochondria in necrotic cell death...