Dagmar Beier

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. pmc Chemoresistance of glioblastoma cancer stem cells--much more complex than expected
    Dagmar Beier
    Department of Neurology, RWTH Aachen, Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany
    Mol Cancer 10:128. 2011
  2. doi Temozolomide preferentially depletes cancer stem cells in glioblastoma
    Dagmar Beier
    Department of Neurology, University of Regensburg, Medical School, Regensburg, Germany
    Cancer Res 68:5706-15. 2008
  3. doi Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines
    Dagmar Beier
    Department of Neurology and JARA Brain, Hospital Medical School, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany
    J Neurooncol 109:45-52. 2012
  4. doi Glioblastoma cancer stem cells--from concept to clinical application
    Barbara E Stopschinski
    Department of Neurology, JARA BRAIN, RWTH Aachen, University Hospital, Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany
    Cancer Lett 338:32-40. 2013
  5. pmc The cancer stem cell subtype determines immune infiltration of glioblastoma
    Christoph P Beier
    Department of Neurology, RWTH Aachen, Aachen, Germany
    Stem Cells Dev 21:2753-61. 2012
  6. pmc RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study
    Christoph P Beier
    Department of Neurology, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    BMC Cancer 9:308. 2009
  7. ncbi CD133 negative cancer stem cells in glioblastoma
    Christoph P Beier
    Department of Neurology, RWTH Aachen, Medical School, Aachen, Germany
    Front Biosci (Elite Ed) 3:701-10. 2011
  8. doi CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors
    Dagmar Beier
    Laboratory of Neurooncology, Department of Neurology, University of Regensburg, Medical School, Regensburg, Germany
    Brain Pathol 18:370-7. 2008
  9. pmc Short-term effective treatment of CNS metastasis of sarcomatoid renal cell carcinoma with temozolomide and pegylated liposomal doxorubicin: A case report
    Dagmar Beier
    Department of Neurology, Medical School, University of Regensburg and District Medical Center Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Cases J 1:210. 2008

Detail Information

Publications9

  1. pmc Chemoresistance of glioblastoma cancer stem cells--much more complex than expected
    Dagmar Beier
    Department of Neurology, RWTH Aachen, Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany
    Mol Cancer 10:128. 2011
    ..Thus, the interaction of CSC and chemotherapy is more complex than may be expected and it is necessary to consider these factors in order to overcome chemoresistance in the patient...
  2. doi Temozolomide preferentially depletes cancer stem cells in glioblastoma
    Dagmar Beier
    Department of Neurology, University of Regensburg, Medical School, Regensburg, Germany
    Cancer Res 68:5706-15. 2008
    ..Accordingly, our data strongly suggest that optimized temozolomide-based chemotherapeutic protocols might substantially improve the elimination of GBM stem cells and consequently prolong the survival of patients...
  3. doi Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines
    Dagmar Beier
    Department of Neurology and JARA Brain, Hospital Medical School, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany
    J Neurooncol 109:45-52. 2012
    ..The 7 days on/7 days off scheme consistently showed the best activity of all schedules in TMZ-resistant CSC lines...
  4. doi Glioblastoma cancer stem cells--from concept to clinical application
    Barbara E Stopschinski
    Department of Neurology, JARA BRAIN, RWTH Aachen, University Hospital, Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany
    Cancer Lett 338:32-40. 2013
    ..This review therefore describes current concepts and controversies on CSC in GBM and summarizes the recent progress how the CSC hypothesis is about to translate into preclinical and clinical application. ..
  5. pmc The cancer stem cell subtype determines immune infiltration of glioblastoma
    Christoph P Beier
    Department of Neurology, RWTH Aachen, Aachen, Germany
    Stem Cells Dev 21:2753-61. 2012
    ..Thus, the molecular subtype of CSCs TGF-beta-dependently contributes to the degree of immune infiltration...
  6. pmc RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study
    Christoph P Beier
    Department of Neurology, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    BMC Cancer 9:308. 2009
    ..Although Temozolomide is effective against glioblastoma, the prognosis remains dismal and new regimens with synergistic activity are sought for...
  7. ncbi CD133 negative cancer stem cells in glioblastoma
    Christoph P Beier
    Department of Neurology, RWTH Aachen, Medical School, Aachen, Germany
    Front Biosci (Elite Ed) 3:701-10. 2011
    ....
  8. doi CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors
    Dagmar Beier
    Laboratory of Neurooncology, Department of Neurology, University of Regensburg, Medical School, Regensburg, Germany
    Brain Pathol 18:370-7. 2008
    ..The presence or absence of CD133(+) CSC might explain the crucial biological difference between WHO grade III and IV oligodendroglial tumors...
  9. pmc Short-term effective treatment of CNS metastasis of sarcomatoid renal cell carcinoma with temozolomide and pegylated liposomal doxorubicin: A case report
    Dagmar Beier
    Department of Neurology, Medical School, University of Regensburg and District Medical Center Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Cases J 1:210. 2008
    ....