Hans G Beger

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi request reprint Treatment of pancreatic cancer: challenge of the facts
    Hans G Beger
    World J Surg 27:1075-84. 2003
  2. ncbi request reprint New advances in pancreatic surgery
    Hans G Beger
    Department of General Surgery, University of Ulm, Department of Visceral Surgery, Neu Ulm, Germany
    Curr Opin Gastroenterol 23:522-34. 2007
  3. doi request reprint Duodenum-preserving total pancreatic head resection for benign cystic neoplastic lesions
    Hans G Beger
    c o Klinikum, University of Ulm, Ulm, Germany
    J Gastrointest Surg 16:2160-6. 2012
  4. doi request reprint Duodenum-preserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas
    H G Beger
    Department of General and Visceral Surgery, University of Ulm 9 2001, Ulm, Germany
    J Gastrointest Surg 12:1127-32. 2008
  5. doi request reprint Duodenum-preserving total pancreatic head resection for cystic neoplasm: a limited but cancer-preventive procedure
    Hans G Beger
    Universitatsklinikum Ulm, Ulm, Germany
    Langenbecks Arch Surg 393:589-98. 2008
  6. doi request reprint Master of surgery in Archiv für Klinische Chirurgie
    H G Beger
    Universitätsklinik Ulm, Steinhovelstrasse 9, Ulm, Germany
    Langenbecks Arch Surg 395:17-21. 2010
  7. ncbi request reprint The art of surgery in the 21st century: based on natural sciences and new ethical dimensions
    H G Beger
    University of Ulm, Steinhoevelstrasse 9, 89075, Ulm, Germany
    Langenbecks Arch Surg 391:143-8. 2006
  8. doi request reprint From Archiv für Klinische Chirurgie to Langenbeck's Archives of Surgery: 1860-2010
    H G Beger
    Universitätsklinik Ulm, Steinhovelstrasse 9, Ulm, Germany
    Langenbecks Arch Surg 395:3-12. 2010
  9. ncbi request reprint Effect of early and late antibiotic treatment in experimental acute pancreatitis in rats
    Michael Schwarz
    Department of General Surgery, University of Ulm, Ulm, Germany
    Langenbecks Arch Surg 392:365-70. 2007
  10. doi request reprint Endotoxemia and endotoxin tolerance in patients with ARDS
    Klaus Buttenschoen
    Department of General Surgery, University of Ulm, Ulm, Germany
    Langenbecks Arch Surg 393:473-8. 2008

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Treatment of pancreatic cancer: challenge of the facts
    Hans G Beger
    World J Surg 27:1075-84. 2003
    ..Therefore, after oncological resection of pancreatic cancer each patient should be offered adjuvant treatment. A neoadjuvant treatment protocol for pancreatic cancer, however, has not been established...
  2. ncbi request reprint New advances in pancreatic surgery
    Hans G Beger
    Department of General Surgery, University of Ulm, Department of Visceral Surgery, Neu Ulm, Germany
    Curr Opin Gastroenterol 23:522-34. 2007
    ....
  3. doi request reprint Duodenum-preserving total pancreatic head resection for benign cystic neoplastic lesions
    Hans G Beger
    c o Klinikum, University of Ulm, Ulm, Germany
    J Gastrointest Surg 16:2160-6. 2012
    ..Complete surgical resection of the benign lesion is a pancreatic cancer preventive treatment...
  4. doi request reprint Duodenum-preserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas
    H G Beger
    Department of General and Visceral Surgery, University of Ulm 9 2001, Ulm, Germany
    J Gastrointest Surg 12:1127-32. 2008
    ..CONCLUSION: The limited surgical procedures of subtotal or total pancreatic head resection are simple, safe, ensures free tumour margins and replace in the authors institution the application of a Whipple-type head resection...
  5. doi request reprint Duodenum-preserving total pancreatic head resection for cystic neoplasm: a limited but cancer-preventive procedure
    Hans G Beger
    Universitatsklinikum Ulm, Ulm, Germany
    Langenbecks Arch Surg 393:589-98. 2008
    ....
  6. doi request reprint Master of surgery in Archiv für Klinische Chirurgie
    H G Beger
    Universitätsklinik Ulm, Steinhovelstrasse 9, Ulm, Germany
    Langenbecks Arch Surg 395:17-21. 2010
    ..Surgeons from Germany contributed strongly to the upturn of operative treatment in the second half of the nineteenth century...
  7. ncbi request reprint The art of surgery in the 21st century: based on natural sciences and new ethical dimensions
    H G Beger
    University of Ulm, Steinhoevelstrasse 9, 89075, Ulm, Germany
    Langenbecks Arch Surg 391:143-8. 2006
    ....
  8. doi request reprint From Archiv für Klinische Chirurgie to Langenbeck's Archives of Surgery: 1860-2010
    H G Beger
    Universitätsklinik Ulm, Steinhovelstrasse 9, Ulm, Germany
    Langenbecks Arch Surg 395:3-12. 2010
    ..A section Achievements and Progress in Surgery referred to published results in national and international medical and surgical journals...
  9. ncbi request reprint Effect of early and late antibiotic treatment in experimental acute pancreatitis in rats
    Michael Schwarz
    Department of General Surgery, University of Ulm, Ulm, Germany
    Langenbecks Arch Surg 392:365-70. 2007
    ..The effect of two antibiotic regimens for early and late treatment was investigated in the taurocholate model of necrotizing pancreatitis in the rat...
  10. doi request reprint Endotoxemia and endotoxin tolerance in patients with ARDS
    Klaus Buttenschoen
    Department of General Surgery, University of Ulm, Ulm, Germany
    Langenbecks Arch Surg 393:473-8. 2008
    ..Exaggerated cytokine release of mononuclear cells was observed in acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, repetitive administration of endotoxin can cause tolerance...
  11. ncbi request reprint Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil
    Marko Kornmann
    Department of General Surgery, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
    Clin Cancer Res 9:4116-24. 2003
    ..In this study, we determined the prognostic value of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) expression in colorectal cancer patients treated with adjuvant 5-FU...
  12. ncbi request reprint The clinical efficacy of adjuvant systemic chemotherapy with gemcitabine and NSC-631570 in advanced pancreatic cancer
    Frank Gansauge
    Center for Oncological, Endocrinological and Minimal access Surgery, University of Ulm, Silcherstr 36, 89231 Neu Ulm, Germany
    Hepatogastroenterology 54:917-20. 2007
    ..The aim of this study was to determine the effectiveness of the combined treatment with Gemcitabine and NSC-631570 in the adjuvant treatment of resected advanced pancreatic cancer...
  13. doi request reprint Duodenum-preserving total pancreatic head resection for cystic neoplastic lesions in the head of the pancreas
    Hans G Beger
    c o Universitätsklinikum Ulm, Steinhovelstrasse 9, D 89075 Ulm, Germany
    J Hepatobiliary Pancreat Surg 15:149-56. 2008
    ..We report the following data from 15 patients treated surgically for cystic neoplastic lesions of the pancreas head...
  14. ncbi request reprint Pancreatic injury in severe trauma: early diagnosis and therapy improve the outcome
    Jens M Mayer
    Department of General Surgery, University Hospital, Ulm, Germany
    Dig Surg 19:291-7; discussion 297-9. 2002
    ..Pancreatic injury is a dangerous complication in multiple injury, and experience with its diagnosis and treatment is usually limited...
  15. ncbi request reprint Acute pancreatitis in transgenic mice expressing human group IIA phospholipase A2
    Jens M Mayer
    Department of General Surgery, University of Ulm, Germany
    Pancreas 25:188-91. 2002
    ..There is circumstantial and contradictory evidence of the role of group IIA phospholipase A2 (PLA2) in acute pancreatitis...
  16. ncbi request reprint The Beger procedure--duodenum-preserving pancreatic head resection
    Hans G Beger
    Department of General Surgery, University of Ulm, Ulm, Germany
    J Gastrointest Surg 8:1090-7. 2004
  17. ncbi request reprint Pseudocyst treatment in chronic pancreatitis--surgical treatment of the underlying disease increases the long-term success
    Wolfgang Schlosser
    Department of General Surgery, University of Ulm, Ulm, Germany
    Dig Surg 22:340-5. 2005
    ..For reasons of persisting controversies concerning indications for surgery, we evaluated chronic pancreatitis patients following pancreatic head resection or drainage procedure for pseudocysts located in the pancreatic head...
  18. ncbi request reprint Pancreatic cancer: who benefits from curative resection?
    Hans G Beger
    Department of General Surgery, University Hospital, University of Ulm, Steinhovelstrasse 9, D 89075 Ulm Donau, Germany
    Can J Gastroenterol 16:117-20. 2002
    ..Adjuvant radiochemotherapy also provides a modest prolongation of survival. Despite these advances, the prognosis for pancreatic cancer is still poor, and spread of tumour within the peritoneum and to the liver is common postoperatively...
  19. doi request reprint Effect of major abdominal surgery on endotoxin release and expression of Toll-like receptors 2/4
    Klaus Buttenschoen
    Department of Surgery, University of Ulm, Ulm, Germany
    Langenbecks Arch Surg 394:293-302. 2009
    ..The objective of the study is to characterize early inflammatory response and expression of TLR2/4 during major abdominal surgery...
  20. ncbi request reprint Severe acute pancreatitis is related to increased early urinary levels of the activation Peptide of pancreatic phospholipase A(2)
    Jens M Mayer
    Department of General Surgery, University Hospital of Ulm, Germany
    Pancreatology 2:535-42. 2002
    ..The aim of this study was to assess time course and level of activation of sPLA(2)-I and trypsinogen in acute pancreatitis, relative to severity...
  21. ncbi request reprint Characteristics of infection with Candida species in patients with necrotizing pancreatitis
    Rainer Isenmann
    Department of General Surgery, University of Ulm, Steinhoevelstrasse 9, 89075 Ulm, Germany
    World J Surg 26:372-6. 2002
    ..Our data provide evidence that application of antibiotics contributes to the development of Candida infection and to changes in the bacterial spectrum of infected necrosis with an increase in the incidence of gram-positive infection...
  22. ncbi request reprint Duodenum-preserving pancreatic head resection leads to relief of common bile duct stenosis
    Wolfgang Schlosser
    Department of General Surgery, University of Ulm, Steinhovelstrasse 9, D 89075 Ulm, Germany
    Am J Surg 183:37-41. 2002
    ..Common bile duct stenosis (CBDS) is one of the most frequent complications in chronic pancreatitis with inflammatory mass in the head of the pancreas (IMH)...
  23. ncbi request reprint Natural history of necrotizing pancreatitis
    Hans G Beger
    Department of General Surgery, University of Ulm, Ulm, Germany
    Pancreatology 3:93-101. 2003
  24. doi request reprint Long-term experience on surgical treatment of alveolar echinococcosis
    Klaus Buttenschoen
    Department of General Surgery, University of Ulm, Steinhoevelstrasse 9, 89075, Ulm, Germany
    Langenbecks Arch Surg 394:689-98. 2009
    ..Alveolar echinococcosis (AE) is life-threatening and reports on surgical procedures and results are rare, but essential...
  25. ncbi request reprint Association of time to recurrence with thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression in stage II and III colorectal cancer
    Marko Kornmann
    Department of General Surgery, University of Ulm, Ulm, Germany
    J Gastrointest Surg 6:331-7. 2002
    ..The TS mRNA level may be a useful marker to predict the time to recurrence in patients with colorectal cancer who are receiving adjuvant 5-FU treatment...
  26. ncbi request reprint Pathogenesis and treatment of neoplastic diseases of the papilla of Vater: Kausch-Whipple procedure with lymph node dissection in cancer of the papilla of Vater
    Hans G Beger
    Department of Surgery, Universiy of Ulm, Ulm, Germany
    J Hepatobiliary Pancreat Surg 11:232-8. 2004
    ..Patients without lymph node involvement, and with absence of infiltration into the pancreas, no lymph vessel invasion, and tumor-negative margins have major benefits from oncological resection in regard to curability of the cancer...
  27. ncbi request reprint Chemosensitivity testing and test-directed chemotherapy in human pancreatic cancer
    Marko Kornmann
    Department of General Surgery, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
    Recent Results Cancer Res 161:180-95. 2003
    ..Our results further suggest that chemotherapy in combination with strategies to increase chemosensitivity may be a reasonable regimen for the treatment of human pancreatic cancer in the future...
  28. ncbi request reprint Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial
    Rainer Isenmann
    Department of Abdominal and Transplantational Surgery, University of Ulm, Germany
    Gastroenterology 126:997-1004. 2004
    ..Antibiotic prophylaxis in necrotizing pancreatitis remains controversial. Until now, there have been no double-blind studies dealing with this topic...
  29. ncbi request reprint IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells
    Marko Kornmann
    Department of General Surgery, University of Ulm, Ulm, Germany
    Gastroenterology 123:301-13. 2002
    ..Pancreatic ductal adenocarcinomas (PDACs) overexpress multiple FGFs, implying a potential for growth modulation. In this study we investigated the importance of the IIIc splice variant of FGFR-1 (FGFR-1 IIIc) in PDAC...
  30. doi request reprint Surgical approaches to chronic pancreatitis
    Andre L Mihaljevic
    Department of General Surgery, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Best Pract Res Clin Gastroenterol 22:167-81. 2008
    ..The latter allow better preservation of the exocrine and endocrine pancreatic function, and provide adequate pain relieve and improvement in the quality of life of CP patients...
  31. pmc Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis
    Adam S Paszkowski
    Departments of General Surgery and Pathology, University of Ulm, Ulm, Germany
    Ann Surg 235:68-76. 2002
    ..To assess the effect of therapeutic inhibition of interleukin 1beta-converting enzyme (ICE) in an experimental model of severe acute pancreatitis (SAP)...
  32. ncbi request reprint NSC-631570 (Ukrain) in the palliative treatment of pancreatic cancer. Results of a phase II trial
    Frank Gansauge
    Department of General Surgery, University of Ulm, Germany
    Langenbecks Arch Surg 386:570-4. 2002
    ..It has been used in complementary herbal medicine for more than 20 years for the treatment of benign and malignant tumors...
  33. ncbi request reprint Ben Eiseman, M.D., Emeritus Professor of Surgery and Medicine, University of Colorado Medical School, Denver, USA. hans.beger@medizin.uni-ulm.de
    Hans G Beger
    Department of Surgery, University Hospital of Ulm, Steinhoevelstrasse 9, 89075 Ulm, Germany
    Langenbecks Arch Surg 389:311-2. 2004
  34. ncbi request reprint Acute pancreatitis: who needs an operation?
    Hans G Beger
    Department of General Surgery, University of Ulm, Steinhoevelstrasse 9, 89075 Ulm, Germany
    J Hepatobiliary Pancreat Surg 9:436-42. 2002
  35. ncbi request reprint Inhibition of nitric oxide synthase does not influence urinary nitrite plus nitrate excretion after renal ischemic injury
    Toshihisa Ogawa
    Department of General Surgery, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
    Langenbecks Arch Surg 386:518-24. 2002
    ..In the present study, we evaluated the role of NO synthase inhibition using N(G)-nitro- L-arginine methyl ester ( L-NAME) in a model of experimental renal I/R injury...
  36. ncbi request reprint Clinical value of lipopolysaccharide-binding protein (LBP) determinations in acute pancreatitis
    Bettina Rau
    Department of General, Visceral, and Vascular Surgery, University of the Saarland, Kirrberger Strasse, 66421 Homburg Saar, Germany
    Langenbecks Arch Surg 388:181-8. 2003
    ..This study investigated the clinical value of measuring LBP for stratifying biochemical severity in acute pancreatitis by using a recently developed fully automated assay technique...
  37. ncbi request reprint Severe acute pancreatitis: Clinical course and management
    Hans G Beger
    World J Gastroenterol 13:5043-51. 2007
    ..Hospital mortality of SAP after interventional or surgical debridement has decreased in high volume centers to below 20%...
  38. ncbi request reprint Role of early multisystem organ failure as major risk factor for pancreatic infections and death in severe acute pancreatitis
    Bettina M Rau
    Department of General, Visceral, and Vascular Surgery, University of the Saarland, Homburg Saar, Germany
    Clin Gastroenterol Hepatol 4:1053-61. 2006
    ..Infection of necrosis is considered as principal determinant of outcome in necrotizing pancreatitis and as potential complication after operative treatment of sterile necrosis. In this report a new concept is proposed...
  39. ncbi request reprint Identification of tobacco-derived compounds in human pancreatic juice
    Bogdan Prokopczyk
    American Health Foundation, Division of Cancer Etiology and Prevention, Valhalla, New York 10595, USA
    Chem Res Toxicol 15:677-85. 2002
    ..This research presents preliminary data that supports the hypothesis that pancreatic tissue is exposed to TSNA and that they may be important contributors to pancreatic carcinogenesis in humans...
  40. ncbi request reprint CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications
    Bettina Rau
    Department of General, Visceral and Vascular Surgery, University of the Saarland, Kirrberger Strasse, 66421, Homburg Saar, Germany
    Intensive Care Med 29:622-9. 2003
    ..However, as little is known about their role in human disease we investigated local and systemic concentrations of different CC-chemokine members in patients with acute pancreatitis...
  41. ncbi request reprint Preventive surgery: the impact of molecular biology in surgery
    Hans G Beger
    Langenbecks Arch Surg 388:1-2. 2003
  42. ncbi request reprint Influence of PMN leukocyte-mediated pancreatic damage on the systemic immune response in severe acute pancreatitis in rats
    Uwe A Wittel
    Department of General, Visceral, and Transplantation Surgery, University of Freiburg, 79106 Freiburg, Germany
    Dig Dis Sci 49:1348-57. 2004
    ..Only the treatment with anti-ICAM-1 mAb affected these changes, indicating that immunological changes in necrotizing pancreatitis are only in part affected by early PMN leukocyte-mediated pancreatic damage...
  43. ncbi request reprint 4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue
    Bogdan Prokopczyk
    Department of Pharmacology, H078, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033 0805, USA
    Cancer Epidemiol Biomarkers Prev 14:540-1. 2005
  44. ncbi request reprint Systemic immune dysfunction in pancreatic cancer patients
    Bertram Poch
    Center for Oncological, Endocrinological and Minimal access Surgery, Silcherstr 36, 89231 Neu Ulm, Germany
    Langenbecks Arch Surg 392:353-8. 2007
    ..We investigated the immune status in 32 pancreatic cancer patients (PC) in comparison with healthy controls (HC)...
  45. ncbi request reprint Acinar cell membrane disruption is an early event in experimental acute pancreatitis in rats
    Michael W Müller
    Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
    Pancreas 35:e30-40. 2007
    ..To test the hypothesis that disruption of acinar cell membranes is the earliest event that takes place after the onset of acute pancreatitis...
  46. ncbi request reprint Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma
    Carmela Beger
    Department of Pediatric Hematology, Hannover Medical School, Hannover, Germany
    Clin Cancer Res 10:3780-7. 2004
    ..However, as demonstrated for breast and ovarian cancer, inactivation of BRCA in sporadic diseases is based on alteration in gene expression or functional alteration...
  47. ncbi request reprint Evaluation of procalcitonin for predicting septic multiorgan failure and overall prognosis in secondary peritonitis: a prospective, international multicenter study
    Bettina M Rau
    Department of General, Visceral, and Vascular Surgery, University of the Saarland, Homburg Saar, Germany
    Arch Surg 142:134-42. 2007
    ..We hypothesized that the laboratory marker procalcitonin would provide an early and reliable assessment of septic complications...
  48. pmc Early assessment of pancreatic infections and overall prognosis in severe acute pancreatitis by procalcitonin (PCT): a prospective international multicenter study
    Bettina M Rau
    Department of General, Visceral, and Vascular Surgery, University of the Saarland, Kirrberger Strasse, 66421 Homburg Saar, Germany
    Ann Surg 245:745-54. 2007
    ..We investigated the value of Procalcitonin (PCT) for identifying patients at risk to develop pancreatic infections in severe AP...
  49. ncbi request reprint 'Understanding the development of pancreatic cancer will emerge from basic research'. An interview with Prof. Hans G. Beger. Interviewed by Martin E. Fernandez-Zapico
    Hans G Beger
    Pancreatology 5:116-8. 2005
    ..In this interview for Pancreatology Prof. Beger shares his life experiences as a scientist in pancreatic research...