Susen Becker

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. doi request reprint LC-MS/MS-based quantification of cholesterol and related metabolites in dried blood for the screening of inborn errors of sterol metabolism
    S Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103, Leipzig, Germany
    Anal Bioanal Chem 407:5227-33. 2015
  2. doi request reprint Evaluation of a novel commercial assay for the determination of cyclosporine A, tacrolimus, sirolimus, and everolimus by liquid chromatography-tandem mass spectrometric assay
    Susen Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    Ther Drug Monit 35:129-32. 2013
  3. doi request reprint Preanalytical Investigation of Polyunsaturated Fatty Acids and Eicosanoids in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry
    Juliane Dorow
    1 Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    Biopreserv Biobank 14:107-13. 2016
  4. doi request reprint Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry
    Uta Ceglarek
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103 Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University Leipzig, Philipp Rosenthal Strasse 27, 04103 Leipzig, Germany
    Clin Chim Acta 435:1-6. 2014
  5. doi request reprint Sample preparation strategies for targeted proteomics via proteotypic peptides in human blood using liquid chromatography tandem mass spectrometry
    Julia Dittrich
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University Leipzig, Leipzig, Germany
    Proteomics Clin Appl 9:5-16. 2015
  6. doi request reprint Quantification of seven apolipoproteins in human plasma by proteotypic peptides using fast LC-MS/MS
    Uta Ceglarek
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany
    Proteomics Clin Appl 7:794-801. 2013
  7. doi request reprint Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque
    Christin Helmschrodt
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Germany Electronic address
    Clin Chim Acta 425:3-8. 2013
  8. doi request reprint Fast liquid chromatography-quadrupole linear ion trap-mass spectrometry analysis of polyunsaturated fatty acids and eicosanoids in human plasma
    Linda Kortz
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstr 27, 04103 Leipzig, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 927:209-13. 2013
  9. ncbi request reprint Impact of clozapine, N-desmethylclozapine and chlorpromazine on thromboxane production in vitro
    Hubertus Himmerich
    Department of Psychiatry, University of Leipzig, Leipzig, Germany
    Med Chem 8:1032-8. 2012
  10. doi request reprint LC-MS-based metabolomics in the clinical laboratory
    Susen Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 883:68-75. 2012

Collaborators

  • Uta Ceglarek
  • Jerzy Roch Nofer
  • Ulrich Sack
  • Linda Kortz
  • Joachim Thiery
  • Juliane Dorow
  • Julia Dittrich
  • Max Hecht
  • Christin Helmschrodt
  • Hubertus Himmerich
  • Sunna Hauschildt
  • Jenny Schröter
  • Gabriela Aust
  • Jeremias Schönherr
  • Abigail J Sheldrick
  • Roland Mergl
  • Luise Schmidt
  • Katrin Bauer

Detail Information

Publications10

  1. doi request reprint LC-MS/MS-based quantification of cholesterol and related metabolites in dried blood for the screening of inborn errors of sterol metabolism
    S Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103, Leipzig, Germany
    Anal Bioanal Chem 407:5227-33. 2015
    ..The developed method enables a rapid quantification of the sum parameter 7- and 8-DHC in newborns and SLOS patients under therapy in serum as well as dried blood spot samples...
  2. doi request reprint Evaluation of a novel commercial assay for the determination of cyclosporine A, tacrolimus, sirolimus, and everolimus by liquid chromatography-tandem mass spectrometric assay
    Susen Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    Ther Drug Monit 35:129-32. 2013
    ....
  3. doi request reprint Preanalytical Investigation of Polyunsaturated Fatty Acids and Eicosanoids in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry
    Juliane Dorow
    1 Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    Biopreserv Biobank 14:107-13. 2016
    ..The arachidonic acid metabolism is useful as a quality marker since eicosanoids are easily subjected to in vitro oxidation processes...
  4. doi request reprint Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry
    Uta Ceglarek
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103 Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University Leipzig, Philipp Rosenthal Strasse 27, 04103 Leipzig, Germany
    Clin Chim Acta 435:1-6. 2014
    ..Preanalytical standardization is required for a reliable quantification of the signaling molecules sphingosine-1-phosphate (S1P), sphinganine-1-phosphate (SA1P) and sphingosine (SPH)...
  5. doi request reprint Sample preparation strategies for targeted proteomics via proteotypic peptides in human blood using liquid chromatography tandem mass spectrometry
    Julia Dittrich
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University Leipzig, Leipzig, Germany
    Proteomics Clin Appl 9:5-16. 2015
    ..The main focus is on the tryptic digestion as a bottleneck of protein quantification via proteotypic peptides. Conclusively, requirements for a high-throughput application are discussed. ..
  6. doi request reprint Quantification of seven apolipoproteins in human plasma by proteotypic peptides using fast LC-MS/MS
    Uta Ceglarek
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany
    Proteomics Clin Appl 7:794-801. 2013
    ....
  7. doi request reprint Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque
    Christin Helmschrodt
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Germany LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Germany Electronic address
    Clin Chim Acta 425:3-8. 2013
    ....
  8. doi request reprint Fast liquid chromatography-quadrupole linear ion trap-mass spectrometry analysis of polyunsaturated fatty acids and eicosanoids in human plasma
    Linda Kortz
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstr 27, 04103 Leipzig, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 927:209-13. 2013
    ..The lower limit of quantitation ranged between 200 and 1000ng/mL for the PUFAs and 10-1000pg/mL for the metabolites. The method was applied to a study on plasma samples from 50 healthy subjects...
  9. ncbi request reprint Impact of clozapine, N-desmethylclozapine and chlorpromazine on thromboxane production in vitro
    Hubertus Himmerich
    Department of Psychiatry, University of Leipzig, Leipzig, Germany
    Med Chem 8:1032-8. 2012
    ..Additionally, known side effects of APs such as orthostatic hypotension may be a result of changes in the concentrations of TxA2 or TxB2...
  10. doi request reprint LC-MS-based metabolomics in the clinical laboratory
    Susen Becker
    Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 883:68-75. 2012
    ..In this context an overview on recent LC-MS/MS based metabolome studies for cancer, diabetes and coronary heart disease is presented...