Research Topics
Genomes and GenesSpecies | Heiko BecherSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Analysing covariates with spike at zero: a modified FP procedure and conceptual issuesHeiko Becher
Institute of Public Health, Medical Faculty, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Biom J 54:686-700. 2012..Further, we check the performance of the procedure in a simulation study and compare it to the previously suggested method, and finally we illustrate the procedures with data from a case-control study on breast cancer...
Process and effects of a community intervention on malaria in rural Burkina Faso: randomized controlled trialBocar Kouyate
Centre de Recherche en Santé de Nouna, Nouna, Burkina Faso, Africa
Malar J 7:50. 2008..Home treatment through mothers of febrile children supported by mother groups and local health workers has the potential to reduce malaria morbidity and mortality...
Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer riskHeiko Becher
Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany
Int J Cancer 116:451-7. 2005..Our study contributes to classifying polycyclic aromatic hydrocarbons as a risk factor for laryngeal cancer...
Risk factors of infant and child mortality in rural Burkina FasoHeiko Becher
University of Heidelberg, Department of Tropical Hygiene and Public Health, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Bull World Health Organ 82:265-73. 2004..The aim of the study was to quantify the effect of risk factors for childhood mortality in a typical rural setting in sub-Saharan Africa...
Reproductive factors and familial predisposition for breast cancer by age 50 years. A case-control-family study for assessing main effects and possible gene-environment interactionHeiko Becher
University of Heidelberg, Department of Tropical Hygiene and Public Health, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Int J Epidemiol 32:38-48. 2003..The effect of environmental/lifestyle factors on breast cancer risk may be modified by genetic predisposition...
Patterns of malaria: cause-specific and all-cause mortality in a malaria-endemic area of west AfricaHeiko Becher
Department of Tropical Hygiene and Public Health, University of Heidelberg, Im Neuenheimer Feld 324, Heidelberg, Germany
Am J Trop Med Hyg 78:106-13. 2008..It is well described parametrically with a sinusoidal function. In adults, the highest all-cause mortality rates were observed in the dry season. Here, HIV/AIDS has become a leading cause of mortality...
Pattern of cause-specific childhood mortality in a malaria endemic area of Burkina FasoGaël P Hammer
Department of Epidemiology, Institute for Tropical Hygiene and Public Health, University of Heidelberg, Germany
Malar J 5:47. 2006..Demographic surveillance systems (DSS) implementing the verbal autopsy (VA) method are the only possibility to observe cause-specific mortality of a population on a longitudinal basis in many countries...
Long-term effects of malaria prevention with insecticide-treated mosquito nets on morbidity and mortality in African children: randomised controlled trialValérie R Louis
Institute of Public Health, Ruprecht Karls University, Heidelberg, Germany
Trop Med Int Health 17:733-41. 2012....
Distribution systems of insecticide-treated bed nets for malaria control in rural Burkina Faso: cluster-randomized controlled trialOlaf Müller
Department of Tropical Hygiene and Public Health, Ruprecht Karls University Heidelberg, Heidelberg, Germany
PLoS ONE 3:e3182. 2008..The objective of this study was to evaluate the effects of free ITN distribution through antenatal care services in addition to an ITN social marketing programme in an area typical for rural SSA...
Effects of insecticide-treated bednets during early infancy in an African area of intense malaria transmission: a randomized controlled trialOlaf Müller
Department of Tropical Hygiene and Public Health, Ruprecht Karls University Heidelberg, Heidelberg, Germany
Bull World Health Organ 84:120-6. 2006..To clarify this issue, we did a randomized controlled trial to assess the long-term effects of bednet protection during early infancy...
Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1Angela Risch
Division of Toxicology and Cancer Risk Factors German Cancer Research Center DKFZ, Heidelberg, Germany
Pharmacogenetics 13:225-30. 2003..As part of the Rhein-Neckar Larynx-case-control study, this study investigated the potential risk-modifying effect of genetic polymorphisms in enzymes involved in ethanol and tobacco carcinogen metabolism for laryngeal cancer in Germany...
Using penalized splines to model age- and season-of-birth-dependent effects of childhood mortality risk factors in rural Burkina FasoHeiko Becher
Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany
Biom J 51:110-22. 2009..Ethnicity is more related to death at early age, as well as age of mother. The effect of the risk factors considered also appear to be related with season of birth...
Cause of death distribution with InterVA and physician coding in a rural area of Burkina FasoHeribert Ramroth
Institute of Public Health, University Hospital of Heidelberg, Heidelberg, Germany
Trop Med Int Health 17:904-13. 2012..To compare the cause of death distribution using the Physician Coded Verbal Autopsy approach versus the Interpreting Verbal Autopsy model, based on information from a French verbal autopsy questionnaire, in rural north-western Burkina Faso...
Prostate cancer in Germany among migrants from the Former Soviet UnionVolker Winkler
University Hospital Heidelberg, Institute of Public Health, Unit of Epidemiology and Biostatistics, Heidelberg, Germany
Glob Health Action 5:9135. 2012..We investigate prostate cancer in Gernmany among migrants from the Former Soviet Union (FSU) and compare them to indigenous German population with regard to prostate cancer incidence, mortality and longitudinal effects...
Multiple pregnancy in rural Burkina Faso: frequency, survival, and use of health servicesAlbrecht Jahn
Department of Tropical Hygiene and Public Health, Ruprecht Karls Universitat Heidelberg, Germany
Acta Obstet Gynecol Scand 85:26-32. 2006..To assess the birth of twins in rural Burkina Faso with respect to prevalence, mortality, and provision of obstetric care...
Mortality from external causes among ethnic German immigrants from former Soviet Union countries, in GermanyCatherine Kyobutungi
Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany
Eur J Public Health 16:376-82. 2006..CONCLUSION: While ethnic German immigrants have a mortality disadvantage compared to the NRW population, it is on a much lower scale than expected if they were representative of their source populations in former Soviet Union countries...
Season of death and birth predict patterns of mortality in Burkina FasoGisela Kynast-Wolf
University of Heidelberg, Germany, Department of Tropical Hygiene and Public Health, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Int J Epidemiol 35:427-35. 2006..Mortality in developing countries has multiple causes. Some of these causes are linked to climatic conditions that differ over the year. Data on season-specific mortality are sparse...
Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control studyAndreas Dietz
Department of Otolaryngology, Head and Neck Surgery, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
Int J Cancer 108:907-11. 2004..We conclude that there is good evidence for cement dust exposure acting as a tobacco, alcohol and asbestos independent risk factor for laryngeal carcinoma. Our study gives a base for further toxicologic investigations on this topic...
Mortality from cancer among ethnic German immigrants from the Former Soviet Union, in GermanyCatherine Kyobutungi
Department of Tropical Hygiene and Public Health, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany
Eur J Cancer 42:2577-84. 2006..Compared to the Russian Federation, Aussiedler had lower all-cancer mortality; males had similar mortality from lung cancers. Better health care in Germany could have resulted in reduced mortality from certain cancers among Aussiedler...
Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genesRashda Abbasi
Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany
Int J Cancer 125:1431-9. 2009..1-fold. SNPs in the other genes did not show a significant association with laryngeal cancer risk. We conclude that common genetic variations in NER genes can significantly modify laryngeal cancer risk...
Risk factors for childhood mortality in sub-Saharan Africa. A comparison of data from a Demographic and Health Survey and from a Demographic Surveillance SystemGaël P Hammer
Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany
Acta Trop 98:212-8. 2006..While most analyses so far determined levels of risk factors, this analysis focuses on the effects of those risk factors...
Seasonal patterns of cardiovascular disease mortality of adults in Burkina Faso, West AfricaGisela Kynast-Wolf
Department of Tropical Hygiene and Public Health, University of Heidelberg, Heidelberg, Germany
Trop Med Int Health 15:1082-9. 2010..To evaluate seasonal patterns of cardiovascular death in adults, which are possibly influenced by hot and dry climate, in a rural setting of Burkina Faso...
ITN protection, MSP1 antibody levels and malaria episodes in young children of rural Burkina FasoGisela Kynast-Wolf
Institute of Public Health, Ruprecht Karls University Heidelberg, Germany
Acta Trop 123:117-22. 2012..The study provides no evidence for antibodies against a subunit of MSP1 being protective against new malaria episodes in infants...
Comparison of all-cause and malaria-specific mortality from two West African countries with different malaria transmission patternsRobert P Ndugwa
Department of Tropical Hygiene and Public Health, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Malar J 7:15. 2008..All-cause and malaria-specific mortality rates for children under-five years old in a mesoendemic malaria area (The Gambia) were compared with those from a hyper/holoendemic area (Burkina Faso)...
All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort studyUlrich Ronellenfitsch
Department of Tropical Hygiene and Public Health, University Hospital of Heidelberg, INF 324, 69120 Heidelberg, Germany
BMC Public Health 6:16. 2006..Because of high overall and CVD mortality in the FSU and low socio-economic status of Aussiedler in Germany, we hypothesize that their mortality is higher...
Cancer profile of migrants from the Former Soviet Union in Germany: incidence and mortalityVolker Winkler
Institute of Public Health, Unit Epidemiology and Biostatistics, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Cancer Causes Control 20:1873-9. 2009..Results confirm that FSU-migrants suffer from cancers, which may be prevented by prevention programs. Furthermore, we cannot conclude a different health-seeking behavior compared to Germans...
The effect of distance to health-care facilities on childhood mortality in rural Burkina FasoAnja Schoeps
Institute of Public Health, University of Heidelberg, Germany
Am J Epidemiol 173:492-8. 2011..The findings of this study emphasize the importance of geographic accessibility of health care for child survival in sub-Saharan Africa and demonstrate the need to improve health-care access to achieve the Millennium Development Goals...
Occupational wood dust exposure and the risk of laryngeal cancer: a population based case-control study in GermanyHeribert Ramroth
Department of Tropical Hygiene and Public Health, University of Heidelberg, Heidelberg, Germany
Am J Ind Med 51:648-55. 2008..To investigate the effect of exposure to wood dust on the risk of laryngeal cancer...
Noncommunicable disease mortality and life expectancy in immigrants to Israel from the former Soviet Union: country of origin compared with host countryJördis Jennifer Ott
Institute of Hygiene, University of Heidelberg, Heidelberg, Germany
Bull World Health Organ 87:20-9. 2009....
Apparent bias for P. falciparum parasites carrying the wild-type pfcrt allele in the placentaNadja Oster
Hygiene Institut, Abteilung Parasitologie, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
Parasitol Res 106:1065-70. 2010..falciparum populations...
Racial differences in breast cancer survival in women under age 60Malabika Sarker
Department of Tropical Hygiene and Public Health, University of Heidelberg, INF 324, 69120, Heidelberg, Germany
Breast Cancer Res Treat 106:135-41. 2007..There is a known difference in breast cancer survival between races in the US for which several factors such as social, lifestyle and genetic factors may be relevant...
The association between protein-energy malnutrition, malaria morbidity and all-cause mortality in West African childrenOlaf Müller
Department of Tropical Hygiene and Public Health, Ruprecht Karls University, Heidelberg, Germany
Trop Med Int Health 8:507-11. 2003..There was no association between PEM and malaria morbidity, but malnourished children had a more than two-fold higher risk of dying than non-malnourished children...
Occupational asbestos exposure as a risk factor for laryngeal carcinoma in a population-based case-control study from GermanyHeribert Ramroth
Institute of Public Health, University of Heidelberg, Germany
Am J Ind Med 54:510-4. 2011..As several studies have identified asbestos exposure as an independent occupational risk factor for laryngeal cancer, the aim of our study was to confirm this association...
Exploring the role narrative free-text plays in discrepancies between physician coding and the InterVA regarding determination of malaria as cause of death, in a malaria holo-endemic regionJohanna C Rankin
Institute of Public Health, University Hospital of Heidelberg, Heidelberg, Germany
Malar J 11:51. 2012....
Chronic disease mortality associated with infectious agents: a comparative cohort study of migrants from the Former Soviet Union in Israel and GermanyJördis J Ott
Department of Tropical Hygiene and Public Health, Medical Faculty of University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
BMC Public Health 8:110. 2008..This study investigates mortality related to infectious diseases with a specific focus on cancers of possibly infectious origin in voluntary migrants from the Former Soviet Union residing in Israel and in Germany...
Patterns of adult and old-age mortality in rural Burkina FasoOsman A Sankoh
Department of Tropical Hygiene and Public Health, University of Heidelberg-Medical School, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany
J Public Health Med 25:372-6. 2003..A seasonal trend in mortality for older people with a peak in February was identified. The study shows that malaria is an important cause of death in adulthood...
Effects of residential changes and time patterns on external-cause mortality in migrants: results of a German cohort studyJördis Jennifer Ott
University of Heidelberg, Institute of Hygiene, Unit of Epidemiology and Biostatistics, Heidelberg, Germany
Scand J Public Health 36:524-31. 2008..Number of residential changes after migration and time period between residential change and death are analysed as predictors for suicide and other causes of mortality...
Environmental tobacco smoke and laryngeal cancer: results from a population-based case-control studyHeribert Ramroth
Department of Tropical Hygiene and Public Health, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Eur Arch Otorhinolaryngol 265:1367-71. 2008..Our findings are in line with the hypothesis that ETS increases the risk of laryngeal cancer. Meta-analyses based on subgroups of nonsmokers from earlier studies are warranted to confirm our findings...
Understanding enrolment in community health insurance in sub-Saharan Africa: a population-based case-control study in rural Burkina FasoManuela De Allegri
Department of Tropical Hygiene and Public Health, University of Heidelberg, Heidelberg, Germany
Bull World Health Organ 84:852-8. 2006..To identify factors associated with decision to enrol in a community health insurance (CHI) scheme...
Predicting lung cancer deaths from smoking prevalence dataVolker Winkler
Institute of Public Health, Unit of Epidemiology and Biostatistics, University of Heidelberg, Heidelberg, Germany
Lung Cancer 74:170-7. 2011..If Ethiopian lung cancer mortality rates in never-smokers and smoking relative risks are the same as in industrialised countries, our models suggests that WHO lung cancer deaths may be underestimated in Ethiopia...
Factors predicting survival after diagnosis of laryngeal cancerHeribert Ramroth
Institute of Public Health, University of Heidelberg, Germany
Oral Oncol 47:1154-8. 2011..For future research it would be desirable to study the effect of treatment on quality of life in multivariate analysis as well as other modifiable risk factors as smoking and drinking reduction or cessation after diagnosis...
Time trends in cardiovascular disease mortality in Russia and Germany from 1980 to 2007 - are there migration effects?Andreas Deckert
Institute of Public Health, University of Heidelberg, INF 324, 69120 Heidelberg, Germany
BMC Public Health 10:488. 2010..We examined to what degree the migration of large subgroups influenced national CVD mortality rates...
Drug utilization patterns and reported health status in ethnic German migrants (Aussiedler) in Germany: a cross-sectional studyAnna Volodina
Institute of Public Health, University of Heidelberg, Germany
BMC Public Health 11:509. 2011..The objective of this study is to investigate drug consumption patterns of ethnic German migrants (Aussiedler) and their current health status...
Malaria in a holoendemic area of Burkina Faso: a cross-sectional studyAugust Stich
Hygiene Institut, Abteilung Parasitologie, , Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
Parasitol Res 98:596-9. 2006..However, the symptom of splenomegaly did show a highly significant association with infection by multiple species of Plasmodium...
Intensity and inhalation of smoking in the aetiology of laryngeal cancerHeribert Ramroth
Institute of Public Health, University of Heidelberg, Im Neuenheimer Feld 324, D 69120 Heidelberg, Germany
Int J Environ Res Public Health 8:976-84. 2011..Changing inhalation habits might be considered as a first step to reducing the risk of developing laryngeal cancer. However, the best way to effectively reduce laryngeal cancer risk is to quit smoking...
Malaria morbidity, treatment-seeking behaviour, and mortality in a cohort of young children in rural Burkina FasoOlaf Müller
Department of Tropical Hygiene and Public Health of the Ruprecht Karls University, Heidelberg, Germany
Trop Med Int Health 8:290-6. 2003..To describe the pattern of fever-associated morbidity, treatment-seeking behaviour for fever episodes, and cause-specific mortality in young children of a malaria-holoendemic area in rural Burkina Faso...
Periodontal disease as a risk factor for ischemic strokeArmin J Grau
Department of Neurology, University of Heidelberg, Heidelberg, Germany
Stroke 35:496-501. 2004..Chronic infectious diseases may increase the risk of stroke. We investigated whether periodontal disease, including periodontitis and gingivitis, is a risk factor for cerebral ischemia...
Reliability of coding causes of death with ICD-10 in GermanyVolker Winkler
Unit of Epidemiology and Biostatistics, Institute of Public Health, University of Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
Int J Public Health 55:43-8. 2010..This study investigates the reliability of national ICD-10 coding practice by assessing agreement of two official coding offices in Germany...
Large-scale, population-based epidemiological studies with record linkage can be done in GermanyUlrich Ronellenfitsch
Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany
Eur J Epidemiol 19:1073-4. 2004..Using the example of a large retrospective cohort study among migrants, we show that this method is also feasible in Germany, a country without central registries and unique identification numbers for citizens...
Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: results of a case-control studyNahid Rajaee-Behbahani
Division of Toxicology and Cancer Risk Factors, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Int J Cancer 98:780-4. 2002..Our results suggest that a reduced capacity of somatic cells to synthesize poly(ADP-ribose) might be associated with an increased risk for laryngeal cancer. The underlying mechanism remains to be investigated...
Effects of tumour stage, comorbidity and therapy on survival of laryngeal cancer patients: a systematic review and a meta-analysisElisabeth Rudolph
Institute of Public Health, University of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany
Eur Arch Otorhinolaryngol 268:165-79. 2011..7-64.7%). Different study aims and patient selection criteria prohibit general conclusions. However, this review may provide an actual picture of the complexity of factors influencing the survival of laryngeal cancer patients...
Widening disparity in survival between white and African-American patients with breast carcinoma treated in the U. S. Department of Defense Healthcare systemIsmail Jatoi
Department of Surgery, U S Army Hospital, Heidelberg, Germany
Cancer 98:894-9. 2003..To examine this issue further, the authors compared trends in survival among white and African-American women diagnosed with breast carcinoma in the U. S. Department of Defense (DoD), an equal access healthcare system...
Seroprevalence of six different viruses among pregnant women and blood donors in rural and urban Burkina Faso: A comparative analysisEllen Collenberg
Abteilung Virologie, Universitaetsklinikum Heidelberg, Heidelberg, Germany
J Med Virol 78:683-92. 2006..3%) than in urban (36.5%) Burkina Faso...
Stomach cancer mortality in two large cohorts of migrants from the Former Soviet Union to Israel and Germany: are there implications for prevention?Ulrich Ronellenfitsch
Department of Surgery, University Medicine Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany
Eur J Gastroenterol Hepatol 21:409-16. 2009..To apply pertinent measures effectively, high-risk groups need to be identified. With this aim, we assessed stomach cancer mortality among migrants from the Former Soviet Union (FSU), a high-risk area, to Germany and Israel...
The association of gingivitis and periodontitis with ischemic strokeChristof E Dorfer
Policlinic for Conservative Dentistry and Periodontology, University of Heidelberg Dental School, Germany
J Clin Periodontol 31:396-401. 2004..The aim of this study was to assess the associations of different periodontal parameters with cerebral ischemia...
Risk factors for cardiovascular and cerebrovascular diseases among ethnic Germans from the former Soviet Union: results of a nested case-control studyEma Kuhrs
Institute of Public Health, University of Heidelberg, Im Neuenheimer Feld 324, Heidelberg 69120, Germany
BMC Public Health 12:190. 2012..In a recent retrospective cohort study it was unexpectedly found that CVD mortality is lower among "Aussiedler" (ethnic Germans from the former Soviet Union) compared to the German population...
Transmission dynamics of pulmonary tuberculosis between autochthonous and immigrant sub-populationsJudit Barniol
Section Clinical Tropical Medicine, Department for Infectious Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany
BMC Infect Dis 9:197. 2009..Besides, we assessed transmission in relation to social mixing using an innovative tool that measures the integration of immigrants into the local social environment...
Intron 3 16 bp duplication polymorphism of p53 is associated with an increased risk for breast cancer by the age of 50 yearsShan Wang-Gohrke
Department of Obstetrics and Gynaecology, Molecular Biology Laboratory, University of Ulm, Germany
Pharmacogenetics 12:269-72. 2002..Our data suggest that inheritance of an intronic polymorphism in the p53 gene increases breast cancer risk appreciably in women by the age of 50 years with a family history of breast cancer in the German population...
Severe anaemia in west African children: malaria or malnutrition?Olaf Müller
Lancet 361:86-7. 2003
Factors affecting the incident juvenile bone tumors in an Austrian case-control studyRainer Frentzel-Beyme
Bremen Institute for Prevention Research, Social Medicine and Epidemiology, University of Bremen, Linzer Strasse 8, D 28359 Bremen, Germany
Cancer Detect Prev 28:159-69. 2004..The factors may become relevant for preventive psychotherapy applied to susceptible persons for improvement of prognosis after surgical therapy in preventing recurrences...
Sex-specific responses to zinc supplementation in Nouna, Burkina FasoMichel Garenne
IRD and Institut Pasteur, Unité d Epidémiologie des Maladies Emergentes, Paris, France
J Pediatr Gastroenterol Nutr 44:619-28. 2007..Children received either a 12.5-mg zinc sulfate tablet or a placebo every day for about 6 months. Outcomes were morbidity, nutritional status, and mortality...
Improving malaria mortality estimates for rural Africa by adding further studiesRobert Peter Ndugwa
Int J Epidemiol 36:242-3; author reply 243-4. 2007
Malnutrition and childhood mortality in developing countriesOlaf Müller
Lancet 367:1978. 2006
Malnutrition, zinc deficiency, and malaria in AfricaOlaf Müller
Lancet 369:2155-6; author reply 2156-7. 2007
Methylene blue as an antimalarial agentR Heiner Schirmer
Biochemistry Center, Heidelberg University, Heidelberg Germany
Redox Rep 8:272-5. 2003..A pilot study with glucose-6-phosphate dehydrogenase-sufficient adult patients has been conducted recently...
