Affiliation: University of Giessen
Colasante C, Chen J, Ahlemeyer B, Baumgart Vogt E. Peroxisomes in cardiomyocytes and the peroxisome / peroxisome proliferator-activated receptor-loop. Thromb Haemost. 2015;113:452-63 pubmed publisher
..The possible impact of peroxisomal dysfunction in the heart is discussed and a model for the modulation of myocardial metabolism via a peroxisome/PPAR-loop is proposed. ..
Oruqaj G, Karnati S, Vijayan V, Kotarkonda L, Boateng E, Zhang W, et al
. Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-Î² signaling. Proc Natl Acad Sci U S A. 2015;112:E2048-57 pubmed publisher
Karnati S, Palaniswamy S, Alam M, Oruqaj G, Stamme C, Baumgart Vogt E. C22-bronchial and T7-alveolar epithelial cell lines of the immortomouse are excellent murine cell culture model systems to study pulmonary peroxisome biology and metabolism. Histochem Cell Biol. 2016;145:287-304 pubmed publisher
Karnati S, Graulich T, Oruqaj G, Pfreimer S, Seimetz M, Stamme C, et al
. Postnatal development of the bronchiolar club cells of distal airways in the mouse lung: stereological and molecular biological studies. Cell Tissue Res. 2016;364:543-57 pubmed publisher
..Taken together, our data are consistent with the concept that the morphological and functional differentiation of club cells is a postnatal phenomenon. ..
Vijayan V, Srinu T, Karnati S, Garikapati V, Linke M, Kamalyan L, et al
. A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide. J Immunol. 2017;198:2414-2425 pubmed publisher
..In conclusion, our findings identify a previously unidentified role for peroxisomes in macrophage inflammatory responses and suggest that peroxisomes are involved in the physiological cessation of macrophage activation. ..
Anthonio E, Brees C, Baumgart Vogt E, Hongu T, Huybrechts S, Van Dijck P, et al
. Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6. BMC Cell Biol. 2009;10:58 pubmed publisher
..In addition, they also lend strong support to and extend the concept that specific Arf isoform pairs may act in tandem to regulate exclusive trafficking pathways. ..