Marek Bartkuhn

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. pmc Active promoters and insulators are marked by the centrosomal protein 190
    Marek Bartkuhn
    Institute for Genetics, Justus Liebig University Giessen, Giessen, Germany
    EMBO J 28:877-88. 2009
  2. pmc The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner
    Frank Sleutels
    Department of Cell Biology Erasmus Medical Center, Rotterdam, The Netherlands
    Epigenetics Chromatin 5:8. 2012
  3. pmc Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation
    Dmitry Popichenko
    Department of Biology, University of Osnabruck, Zoology, Osnabruck, Germany
    BMC Dev Biol 7:49. 2007
  4. pmc The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning
    Man Mohan
    Institute for Genetics, Justus Liebig University Giessen, Heinrich Buff Ring, Giessen, Germany
    EMBO J 26:4203-14. 2007
  5. pmc Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites
    Oliver Weth
    Institute for Genetics, Justus Liebig University Giessen, Giessen, Germany
    PLoS ONE 5:e10119. 2010
  6. pmc Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
    Katharina Günther
    Institute for Genetics, Justus Liebig University, D35392 Giessen, Germany
    Nucleic Acids Res 41:3010-21. 2013
  7. doi request reprint Long range chromatin interactions involved in gene regulation
    Marek Bartkuhn
    Institute for Genetics, Justus Liebig University Giessen, Heinrich Buff Ring 58 62, 35392 Giessen, Germany
    Biochim Biophys Acta 1783:2161-6. 2008
  8. doi request reprint The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men
    Cornelia Steilmann
    Department of Urology, Pediatric Urology and Andrology, Rudolf Buchheim Strasse 7, Justus Liebig University, 35385 Giessen, Germany
    Reproduction 140:435-43. 2010
  9. doi request reprint Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression
    Katja Handschick
    Rudolf Buchheim Institute of Pharmacology, Justus Liebig University Giessen, 35392 Giessen, Germany
    Mol Cell 53:193-208. 2014
  10. pmc Genome wide identification of promoter binding sites for H4K12ac in human sperm and its relevance for early embryonic development
    Agnieszka S Paradowska
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
    Epigenetics 7:1057-70. 2012

Collaborators

Detail Information

Publications13

  1. pmc Active promoters and insulators are marked by the centrosomal protein 190
    Marek Bartkuhn
    Institute for Genetics, Justus Liebig University Giessen, Giessen, Germany
    EMBO J 28:877-88. 2009
    ..Loss of either dCTCF or CP190 causes an increase of H3 and H3K27 trimethylation at these sites. Thus, for both types of cis-regulatory elements, domain borders and promoters, the chromatin structure is dependent on CP190...
  2. pmc The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner
    Frank Sleutels
    Department of Cell Biology Erasmus Medical Center, Rotterdam, The Netherlands
    Epigenetics Chromatin 5:8. 2012
    ..abstract:..
  3. pmc Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation
    Dmitry Popichenko
    Department of Biology, University of Osnabruck, Zoology, Osnabruck, Germany
    BMC Dev Biol 7:49. 2007
    ..In our report we focus on the analysis of the transcriptional control of the highly conserved transcription factor Hand in circular visceral muscle cells, providing evidence that the hand gene is a direct target of Biniou...
  4. pmc The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning
    Man Mohan
    Institute for Genetics, Justus Liebig University Giessen, Heinrich Buff Ring, Giessen, Germany
    EMBO J 26:4203-14. 2007
    ..A short pulse of dCTCF expression during larval development rescues the dCTCF loss of function phenotype. Overall, we demonstrate the importance of dCTCF in fly development and in the regulation of abdominal segmentation...
  5. pmc Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites
    Oliver Weth
    Institute for Genetics, Justus Liebig University Giessen, Giessen, Germany
    PLoS ONE 5:e10119. 2010
    ..Thus, a number of composite CTCF/TR binding sites may represent a subset of other modular CTCF composite sites, such as groups of multiple CTCF sites or of CTCF/Oct4, CTCF/Kaiso or CTCF/Yy1 combinations...
  6. pmc Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
    Katharina Günther
    Institute for Genetics, Justus Liebig University, D35392 Giessen, Germany
    Nucleic Acids Res 41:3010-21. 2013
    ..Most strikingly, MBD3 is enriched at active promoters, whereas MBD2 is bound at methylated promoters and enriched at exon sequences of active genes...
  7. doi request reprint Long range chromatin interactions involved in gene regulation
    Marek Bartkuhn
    Institute for Genetics, Justus Liebig University Giessen, Heinrich Buff Ring 58 62, 35392 Giessen, Germany
    Biochim Biophys Acta 1783:2161-6. 2008
    ..With more sophisticated and sensitive methods combined with deep sequencing and array technology, a huge number of long range interactions can expected to be characterized in the near future...
  8. doi request reprint The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men
    Cornelia Steilmann
    Department of Urology, Pediatric Urology and Andrology, Rudolf Buchheim Strasse 7, Justus Liebig University, 35385 Giessen, Germany
    Reproduction 140:435-43. 2010
    ..Our data suggest that reduced histone methylation in the promoter of BRDT may be associated with increased transcript levels in subfertile patients...
  9. doi request reprint Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression
    Katja Handschick
    Rudolf Buchheim Institute of Pharmacology, Justus Liebig University Giessen, 35392 Giessen, Germany
    Mol Cell 53:193-208. 2014
    ....
  10. pmc Genome wide identification of promoter binding sites for H4K12ac in human sperm and its relevance for early embryonic development
    Agnieszka S Paradowska
    Department of Urology, Pediatric Urology and Andrology, Justus Liebig University of Giessen, Giessen, Germany
    Epigenetics 7:1057-70. 2012
    ..Aberrant histone acetylation within developmentally important gene promoters in infertile men may reflect insufficient sperm chromatin compaction, which may result in inappropriate transfer of epigenetic information to the oocyte...
  11. pmc CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin
    Les J Burke
    Institute for Genetics, Justus Liebig Universitaet Giessen, Giessen, Germany
    EMBO J 24:3291-300. 2005
    ..In contrast, the enhancer/promoter loop of the same locus is lost in mitosis. This may provide a novel form of epigenetic memory during cell division...
  12. pmc From human monocytes to genome-wide binding sites--a protocol for small amounts of blood: monocyte isolation/ChIP-protocol/library amplification/genome wide computational data analysis
    Sebastian Weiterer
    Department of Anesthesiology and Intensive Care Medicine, Justus Liebig University Giessen, Germany German Centre for Infection Research DZIF, partner site Giessen Marburg Langen, Giessen, Germany
    PLoS ONE 9:e94164. 2014
    ....
  13. pmc The chromatin insulator CTCF and the emergence of metazoan diversity
    Peter Heger
    Institute for Genetics, Cologne Biocenter, University of Cologne, 50674 Cologne, Germany
    Proc Natl Acad Sci U S A 109:17507-12. 2012
    ..Such a kernel could explain (i) the formation of Hox clusters in Bilateria, (ii) the diversity of bilaterian body plans, and (iii) the uniqueness and time of onset of the Cambrian explosion...