Frank Autschbach

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells
    Martin Klemke
    Department of Immunology and Serology, University of Heidelberg, D 69120 Heidelberg, Germany
    Int J Cancer 120:2590-9. 2007
  2. ncbi request reprint Idiopathic megacolon
    Frank Autschbach
    University Heidelberg, Institute of Pathology, Heidelberg, Germany
    Eur J Gastroenterol Hepatol 19:399-400. 2007
  3. ncbi request reprint Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease
    Frank Autschbach
    Institute of Pathology, Heidelberg University, Im Neuenheimer Feld 220 221, 69120 Heidelberg, Germany
    Virchows Arch 441:500-13. 2002
  4. ncbi request reprint Expression of chemokine receptors in normal and inflamed human intestine, tonsil, and liver--an immunohistochemical analysis with new monoclonal antibodies from the 8th international workshop and conference on human leucocyte differentiation antigens
    Frank Autschbach
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Cell Immunol 236:110-4. 2005
  5. ncbi request reprint The pathological assessment of total mesorectal excision: what are the relevant resection margins?
    Frank Autschbach
    Institute of Pathology, Heidelberg University, Im Neuenheimer Feld 220 221, 69120 Heidelberg, Germany
    Recent Results Cancer Res 165:30-9. 2005
  6. doi request reprint Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in Crohn's disease
    Benjamin Funke
    Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Inflamm Bowel Dis 17:1943-54. 2011
  7. doi request reprint DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands
    Caroline End
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Eur J Immunol 39:833-42. 2009
  8. ncbi request reprint A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation
    Bernd Sido
    Department of Surgery, Ruprecht Karls University, Heidelberg, Germany
    Gastroenterology 134:179-91. 2008
  9. pmc Decoy receptor 3 is a prognostic factor in renal cell cancer
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
    Neoplasia 10:1049-56. 2008
  10. ncbi request reprint Aberrant gata-3 expression in human pancreatic cancer
    Antanas Gulbinas
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110 69120, Heidelberg, Germany
    J Histochem Cytochem 54:161-9. 2006

Detail Information

Publications54

  1. ncbi request reprint Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells
    Martin Klemke
    Department of Immunology and Serology, University of Heidelberg, D 69120 Heidelberg, Germany
    Int J Cancer 120:2590-9. 2007
    ..These data show that an increase in melanoma cell invasiveness requires not only expression but also phosphorylation of L-plastin...
  2. ncbi request reprint Idiopathic megacolon
    Frank Autschbach
    University Heidelberg, Institute of Pathology, Heidelberg, Germany
    Eur J Gastroenterol Hepatol 19:399-400. 2007
    ..Innovative molecular techniques are needed to get further insights into the pathogenesis of these intestinal motility disorders...
  3. ncbi request reprint Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease
    Frank Autschbach
    Institute of Pathology, Heidelberg University, Im Neuenheimer Feld 220 221, 69120 Heidelberg, Germany
    Virchows Arch 441:500-13. 2002
    ..Local recruitment of MRP-14 positive leukocytes might contribute to this phenomenon. In inactive UC a phenotypically altered population of macrophages expressing CD14 might play an additional role...
  4. ncbi request reprint Expression of chemokine receptors in normal and inflamed human intestine, tonsil, and liver--an immunohistochemical analysis with new monoclonal antibodies from the 8th international workshop and conference on human leucocyte differentiation antigens
    Frank Autschbach
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Cell Immunol 236:110-4. 2005
    ..Enhanced expression of such molecules likely contributes to the maintenance of inflammation in chronic inflammatory bowel disease...
  5. ncbi request reprint The pathological assessment of total mesorectal excision: what are the relevant resection margins?
    Frank Autschbach
    Institute of Pathology, Heidelberg University, Im Neuenheimer Feld 220 221, 69120 Heidelberg, Germany
    Recent Results Cancer Res 165:30-9. 2005
    ..Careful macroscopic assessment of the resection specimen should be performed to monitor the quality of mesorectal excision...
  6. doi request reprint Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in Crohn's disease
    Benjamin Funke
    Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Inflamm Bowel Dis 17:1943-54. 2011
    ..Employing a global gene expression analysis, this study was aimed at identifying specifically regulated genes within the epithelial compartment in inflammatory bowel disease (IBD)...
  7. doi request reprint DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands
    Caroline End
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Eur J Immunol 39:833-42. 2009
    ....
  8. ncbi request reprint A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation
    Bernd Sido
    Department of Surgery, Ruprecht Karls University, Heidelberg, Germany
    Gastroenterology 134:179-91. 2008
    ..We aimed to determine the role of the redoxactive microenvironment for hyporeactivity of LP-T in normal human gut vs hyperreactivity of LP-T in inflammatory bowel disease...
  9. pmc Decoy receptor 3 is a prognostic factor in renal cell cancer
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
    Neoplasia 10:1049-56. 2008
    ..Decoy receptor 3 (DcR3) is a soluble protein that binds to and inactivates the death ligand CD95L. Here, we studied a possible association between DcR3 expression and prognosis in patients with renal cell carcinomas (RCCs)...
  10. ncbi request reprint Aberrant gata-3 expression in human pancreatic cancer
    Antanas Gulbinas
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110 69120, Heidelberg, Germany
    J Histochem Cytochem 54:161-9. 2006
    ..Furthermore, strong specific upregulation of Gata-3 impaired nuclear translocation and its cooperative action with the TGF-beta pathway, suggesting that Gata-3 plays a central role in human pancreatic cancer...
  11. ncbi request reprint Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine
    Nikolaus Gassler
    Department of Pathology, University of Heidelberg, Heidelberg, Germany
    J Pathol 202:188-96. 2004
    ..These results suggest that deranged acyl-CoA synthetase 5 expression, synthesis, and activity are closely related to the state of villus architecture and epithelial homeostasis in human small intestine...
  12. doi request reprint CT and endoscopic ultrasound in comparison to endoluminal MRI: preliminary results in staging gastric carcinoma
    Tobias Heye
    Department of Diagnostic Radiology, University Hospital, Heidelberg, Germany
    Eur J Radiol 70:336-41. 2009
    ..To prospectively compare diagnostic parameters of a newly developed endoluminal MRI (endo-MRI) concept with endoscopic ultrasound (EUS) and hydro-computer tomography (Hydro-CT) in T-staging of gastric carcinoma on one patient collective...
  13. doi request reprint High nuclear Livin expression is a favourable prognostic indicator in renal cell carcinoma
    Axel Haferkamp
    Department of Urology, University of Heidelberg, Heidelberg, Germany
    BJU Int 102:1700-6. 2008
    ..To assess the protein expression of Livin, an apoptosis inhibitor, in renal cell carcinoma (RCC) and to determine its prognostic relevance...
  14. ncbi request reprint Wnt-signaling and apoptosis after neoadjuvant short-term radiotherapy for rectal cancer
    Nikolaus Gassler
    Department of Pathology, University of Heidelberg, Heidelberg, Germany
    Int J Oncol 25:1543-9. 2004
    ..The molecular profile suggests that STNR interferes with Wnt-signaling and c-Myc expression. STNR in its present form is not suitable to fully complete the sequence of apoptosis in all rectal adenocarcinomas...
  15. doi request reprint Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study
    Wolfgang Stremmel
    Department of Gastroenterology, University Hospital Heidelberg, Heidelberg, Germany
    J Clin Gastroenterol 44:e101-7. 2010
    ..In 2 preceding studies, delayed release phosphatidylcholine (rPC) was found to (a) improve disease activity and (b) withdraw steroids in patients with chronic-active ulcerative colitis...
  16. doi request reprint High-mobility group box-1 in ischemia-reperfusion injury of the heart
    Martin Andrassy
    Department of Medicine III, University of Heidelberg, Heidelberg, Germany
    Circulation 117:3216-26. 2008
    ..Although HMGB1 has been implicated in ischemia/reperfusion (I/R) injury of the liver and lung, its role in I/R injury of the heart remains unclear...
  17. ncbi request reprint Endoscopic posterior mesorectal resection as an option to combine local treatment of early stage rectal cancer with partial mesorectal lymphadenectomy
    Jörg Köninger
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany
    Langenbecks Arch Surg 392:567-71. 2007
    ..Local excision of low rectal cancer is regarded as an alternative to radical surgery; however, occurrence of lymph node metastasis even in patients with highly differentiated early-stage rectal cancer may be underestimated...
  18. ncbi request reprint DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease
    Marcus Renner
    Division of Molecular Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Gastroenterology 133:1499-509. 2007
    ..Here, we aimed at analyzing the role of DMBT1 in IBD...
  19. ncbi request reprint Diagnosing pouchitis: comparative validation of two scoring systems in routine follow-up
    Udo A Heuschen
    Department of Surgery, University of Heidelberg, Heidelberg, Germany
    Dis Colon Rectum 45:776-86; discussion 786-8. 2002
    ..The aim of the present study was to validate two existing scoring systems in routine outpatient practice...
  20. ncbi request reprint Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing
    Nikolaus Gassler
    Institute of Pathology, Rheinisch Westfälische Technische Hochschule RWTH Aachen University, Aachen, Germany
    Gastroenterology 133:587-98. 2007
    ..The aim of the present study was to examine underlying molecular mechanisms of the cell death at the villus tip...
  21. doi request reprint Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect
    Annika Braun
    Department of Gastroenterology, University Hospital Heidelberg, INF 410, 69120, Heidelberg, Germany
    Int J Colorectal Dis 26:989-98. 2011
    ..The hydrophobicity of the colonic mucosal surface is a measure of its resistance to luminal antigens, e.g. of bacterial origin. Therefore, the purpose of this study was to determine this parameter in patients suffering from IBD...
  22. pmc Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E
    Johannes Kapeller
    Department of Human Molecular Genetics, University of Heidelberg, Germany
    J Comp Neurol 519:420-32. 2011
    ....
  23. doi request reprint First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome
    Johannes Kapeller
    Department of Human Molecular Genetics, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany
    Hum Mol Genet 17:2967-77. 2008
    ..This is the first example indicating micro RNA-related expression regulation of a serotonin receptor gene with a cis-regulatory variant affecting this regulation and appearing to be associated with female IBS-D...
  24. pmc Posttranslationally modified proteins as mediators of sustained intestinal inflammation
    Martin Andrassy
    Department of Medicine I, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Am J Pathol 169:1223-37. 2006
    ..Thus, CML-mps generated in inflammatory lesions have the capacity to elicit a RAGE-dependent intestinal inflammatory response...
  25. doi request reprint Noncompaction myocardium in association with type Ib glycogen storage disease
    Benjamin Goeppert
    Institute of Pathology, University Hospital Heidelberg, Germany
    Pathol Res Pract 208:620-2. 2012
    ..The present case represents the first report of a noncompaction myocardium in a child with type Ib GSD who died of sudden clinical deterioration at the age of four...
  26. ncbi request reprint Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment
    Pascal O Berberat
    Division of Pancreatic Surgery and Molecular Pancreatic Research, Department of General Surgery, Institute of Immunology, University of Heidelberg, Heidelberg, Germany
    Clin Cancer Res 11:3790-8. 2005
    ..Therefore, specific inhibition of HO-1 expression may be a new option in pancreatic cancer therapy and may be used as sensitizer to chemotherapy and radiotherapy...
  27. doi request reprint Prognostic value of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors in renal cell cancer
    Stephan Macher-Goeppinger
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Clin Cancer Res 15:650-9. 2009
    ..Here, we studied a possible association between the expression of TRAIL/TRAIL-Rs and the prognosis in patients with renal cell carcinomas (RCC)...
  28. ncbi request reprint Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial
    Wolfgang Stremmel
    Department of Gastroenterology, University Hospital Heidelberg, Heidelberg, Germany
    Ann Intern Med 147:603-10. 2007
    ..An insufficient level of phosphatidylcholine in colonic mucus is a possible pathogenetic factor for ulcerative colitis...
  29. ncbi request reprint Impaired expression of acyl-CoA-synthetase 5 in epithelial tumors of the small intestine
    Nikolaus Gassler
    Department of Pathology, University of Heidelberg, Germany
    Hum Pathol 34:1048-52. 2003
    ..In conclusion, altered expression of ACS5 is probably related to the adenoma-carcinoma sequence of small intestinal epithelial tumors due to an impaired acyl-CoA thioester synthesis...
  30. pmc Decreased detection rate of disseminated tumor cells of rectal cancer patients after preoperative chemoradiation: a first step towards a molecular surrogate marker for neoadjuvant treatment in colorectal cancer
    Peter Kienle
    Division for Molecular Diagnostics and Therapy and Division for Surgical Oncology of the Department of Surgery, University of Heidelberg, Germany
    Ann Surg 238:324-30; discussion 330-1. 2003
    ..To compare the detection rates for rectal cancer cells in blood and bone marrow in patients with or without preoperative chemoradiation...
  31. ncbi request reprint Increase in substance P precursor mRNA in noninflamed small-bowel sections in patients with Crohn's disease
    Christoph W Michalski
    Department of General Surgery, University of Heidelberg, Im Neuenheimer Feld 110, D 69120 Heidelberg, Germany
    Am J Surg 193:476-81. 2007
    ....
  32. ncbi request reprint Liver-homing of purified glucose oxidase: a novel in vivo model of physiological hepatic oxidative stress (H2O2)
    Daniel Rost
    Department of Medicine, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    J Hepatol 46:482-91. 2007
    ..Reactive oxygen species (ROS), such as H2O2, are implicated in normal and pathological liver function. However, due to the lack of suitable in vivo models of ROS generation the (patho) physiological relevance of H2O2 remains controversial...
  33. ncbi request reprint Familial early onset sarcoidosis with bone cysts and erosions
    Norbert Blank
    Department of Internal Medicine V, Division of Rheumatology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Skeletal Radiol 36:891-3. 2007
    ..This is the first report demonstrating bone cysts and erosions which could be a diagnostic feature in this rare disease and may help to differentiate other rheumatoid disorders...
  34. ncbi request reprint Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis
    Alexandra Zahn
    Department of Gastroenterology, University Hospital of Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    World J Gastroenterol 13:1687-95. 2007
    ..To study susceptibility genes which may play a potential role in the pathogenesis and etiology of inflammatory bowel disease (IBD)...
  35. ncbi request reprint Expression of calnexin reflects paneth cell differentiation and function
    Nikolaus Gassler
    Department of Pathology, Heidelberg University, Mannheim, Germany
    Lab Invest 82:1647-59. 2002
    ..In conclusion, calnexin probably reflects the status of Paneth cell differentiation and function. The results do not necessarily indicate that calnexin has a function in Paneth cell proliferation...
  36. ncbi request reprint Sulfated glycosphingolipid as mediator of phagocytosis: SM4s enhances apoptotic cell clearance and modulates macrophage activity
    Zoran V Popovic
    Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany
    J Immunol 179:6770-82. 2007
    ..These data suggest that SM4s within tumors may promote apoptotic cell removal and alter the phenotype of tumor-associated macrophages...
  37. ncbi request reprint Pathology of the large intestine in patients with vascular type Ehlers-Danlos syndrome
    Hendrik Blaker
    Institute of Pathology, University of Heidelberg, INF 220, 69120 Heidelberg, Germany
    Virchows Arch 450:713-7. 2007
    ..These findings are not seen in other diseases of the colon and should prompt the pathologist to include Ehlers-Danlos syndrome type IV in the differential diagnosis of spontaneous bowel perforation in younger patients...
  38. ncbi request reprint Control of T-cell-mediated immune response by HLA class I in human pancreatic carcinoma
    Eduard Ryschich
    Unit for Documentation and Statistics, Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
    Clin Cancer Res 11:498-504. 2005
    ..Cell surface HLA class I molecules present peptides derived from human cellular proteins to T cells. In the present study, we investigated the expression of HLA class I in human pancreatic carcinoma...
  39. ncbi request reprint CD4+CD25+ cell depletion from the normal CD4+ T cell pool prevents tolerance toward the intestinal flora and leads to chronic colitis in immunodeficient mice
    Claudia Veltkamp
    Department of Gastroenterology, Ruprecht Karls University, Heidelberg, Germany
    Inflamm Bowel Dis 12:437-46. 2006
    ....
  40. doi request reprint Sexual pseudo-precocity caused by a somatic activating mutation of the LH receptor preceding true sexual precocity
    Daniela Kiepe
    Division of Pediatric Endocrinology and Diabetology, University Children s Hospital, Heidelberg, Germany
    Horm Res 70:249-53. 2008
    ..We describe the clinical features of a 6-year-old boy with sexual precocity caused by a somatic activating mutation of the luteinizing hormone (LH) receptor gene preceding gonadotropin-releasing hormone (GnRH)-dependent sexual precocity...
  41. ncbi request reprint Analysis of chromosomal imbalances by comparative genomic hybridisation of pigmented villonodular synovitis
    Irina Berger
    Institute of Pathology, Ruprecht Karls University, Im Neienheimer Feld 220 221, Heidelberg D 69120, Germany
    Cancer Lett 220:231-6. 2005
    ..No losses were found. One of the cases showed an aneuploid DNA-pattern, which actually proved to be the case with the most numerical chromosomal changes...
  42. ncbi request reprint Endothelial inducible costimulator ligand expression is increased during human cardiac allograft rejection and regulates endothelial cell-dependent allo-activation of CD8+ T cells in vitro
    Roland Klingenberg
    Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany
    Eur J Immunol 35:1712-21. 2005
    ..04). Our data indicate a distinct role for ICOSL in EC-mediated CD8(+) T cell costimulation with implications for human cardiac allograft rejection...
  43. doi request reprint Primary chondrosarcoma of the kidney: case report and review of the literature
    Stephan Buse
    Department of Urology, University of Heidelberg Medical School, Heidelberg, Germany
    Urol Int 83:116-8. 2009
    ..We present a case of primary renal chondrosarcoma, its diagnosis and management...
  44. pmc New coil concept for endoluminal MR imaging: initial results in staging of gastric carcinoma in correlation with histopathology
    Tobias Heye
    Department of Diagnostic Radiology, Ruprecht Karls University, Heidelberg, Germany
    Eur Radiol 16:2401-9. 2006
    ..Further investigations in in vivo settings should explore the potential of our coil concept for endoluminal MR imaging...
  45. ncbi request reprint Potential role of thioredoxin in immune responses in intestinal lamina propria T lymphocytes
    Bernd Sido
    Department of Surgery, University of Heidelberg, Heidelberg, Germany
    Eur J Immunol 35:408-17. 2005
    ..TRX may play a key role in the specialized intestinal microenvironment in amplifying immediate immune responses of LP-T whenever appropriate costimulation of LP-T is provided...
  46. ncbi request reprint Diagnostic accuracy of staging renal cell carcinomas using multidetector-row computed tomography and magnetic resonance imaging: a prospective study with histopathologic correlation
    Peter J Hallscheidt
    Department of Diagnostic Radiology, University of Heidelberg, Germany
    J Comput Assist Tomogr 28:333-9. 2004
    ..The aim of this prospective study is to compare the diagnostic accuracy of multidetector-row computed tomography (CT) and magnetic resonance imaging (MRI) in tumor staging of renal cell carcinomas...
  47. pmc Risk factors for ileoanal J pouch-related septic complications in ulcerative colitis and familial adenomatous polyposis
    Udo A Heuschen
    Department of Surgery, University of Heidelberg, Heidelberg, Germany
    Ann Surg 235:207-16. 2002
    ..To analyze the association between pre- and perioperative factors and pouch-related septic complications (PRSC) in ulcerative colitis (UC) and in familial adenomatous polyposis (FAP) after ileal pouch-anal anastomosis (IPAA)...
  48. ncbi request reprint Isolated left ventricular noncompaction of the myocardium as a cause of embolic superior mesenteric artery occlusion
    Erwin Blessing
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    J Am Soc Echocardiogr 18:693. 2005
    ..We describe a case where isolated noncompaction of the LV myocardium was diagnosed after an embolic occlusion of the superior mesenteric artery in a 40-year-old Caucasian woman...
  49. ncbi request reprint Calcification of myocardial necrosis is common in mice
    Susanne Korff
    Department of Medicine III, Division of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany
    Virchows Arch 448:630-8. 2006
    ..We concluded that the susceptibility to calcification of myocardial necrosis may be common among inbred strains and should be recognised as a strong genetic modifier of experimental myocardial injury...
  50. ncbi request reprint Chronic corticosterone-induced deterioration in rat behaviour is not paralleled by changes in hippocampal NF-kappaB-activation
    Konstanze Plaschke
    Clinic of Anaesthesiology, University of Heidelberg, Im Neuenheimer Feld 110, D 69120, Heidelberg, Germany
    Stress 9:97-106. 2006
    ..Thus, cognitive alterations in rats seen after chronic corticosterone exposure are not paralleled by hippocampal NF-kappaB modulation...
  51. ncbi request reprint Differential expression of toll-like receptor 3 and 5 in ileal pouch mucosa of ulcerative colitis patients
    Gundi Heuschen
    Department of Surgery, St Vincenz Krankenhaus, Limburg, Germany
    Int J Colorectal Dis 22:293-301. 2007
    ..Their activation can lead to secretion of proinflammatory mediators. In this study, TLR2, 3, 4, and 5 expression profiles in the pouch mucosa of patients with UC and IPAA were analyzed and correlated with pouchitis...
  52. doi request reprint Schistosomiasis in an HIV-positive patient presenting as an anal fissure and giant anal polyp
    Patrick Gholam
    Arch Dermatol 144:950-2. 2008
  53. ncbi request reprint Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion
    Philip Rosenstiel
    Institute of Clinical Molecular Biology, University Hospital Schleswig Holstein, Campus Kiel, Schittenhelmstrache 12, Kiel, Germany
    J Immunol 178:8203-11. 2007
    ..Dysregulated intestinal DMBT1 expression due to mutations in the NOD2/CARD15 gene may be part of the complex pathophysiology of barrier dysfunction in Crohn's disease...
  54. ncbi request reprint Prevalence of silent gastric ulcer, erosions or severe acute gastritis in patients with type 2 diabetes mellitus--a cross-sectional study
    Michael W J Boehme
    Wilhelm Fresenius Klinik Dr Horst Schmidt Kliniken, Department of Internal Medicine, Wiesbaden, Germany
    Hepatogastroenterology 54:643-8. 2007
    ..The aim of the present study was to evaluate the prevalence of silent severe acute gastritis, gastric ulcers or erosions in asymptomatic patients with diabetes mellitus and to determine potential predictive parameters...